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The map label for this gene is fpr [H]

Identifier: 116515292

GI number: 116515292

Start: 398079

End: 398825

Strand: Direct

Name: fpr [H]

Synonym: BCc_378

Alternate gene names: 116515292

Gene position: 398079-398825 (Clockwise)

Preceding gene: 116515291

Following gene: 116515295

Centisome position: 95.6

GC content: 19.41

Gene sequence:

>747_bases
ATGAATCCATGGTTAGAAATAAAATTAATTGCTATAAAAAAATGGAAAAACAATTTATTTTCATTAATTGTACAAGCACC
TATTAATAAATTTATAGCCGGACAATTTACTAAACTTTCTTATATAAAAAAAAATAAAAAAAGAATACAAAGAGCGTATT
CATTTGTTAATAGTCCAAATAGTAAAAATTTAGAATTCTATATCTTATTAATTAAAAATGGGTTATTAACACCAAAATTA
TATGATATAAAAAATAATAAAATTTTTATTTCAAAAAATTCCTTTGGTTTTTTTACTATTTCAGAATTACCTAAAAAAGA
AAATTTATGGATGATTGCTACTGGTACAGCAATAGGTCCTTATTGTTCTATTTTAAAATATGAAAATATATTAAAAAAAT
TTAAAAAAATCATATTAATACATGCAGTTAAATATAGTATTGATTTAAATTATTTAAATTTATTTAAAAAAATAAAAAAA
AAATATAAAAAAAACATAAAAATAAAAATAATATTAAGTCAAGAAAAAAGAAAAGATTATTTATTTGGTCGTATACCGAA
TTTAATTGCATCTGGAGAATTAGAAAAATCAGTCAAAGAACCATTAAATTCTAAAAATTCACATGTAATGTTATGCGGAA
ATCCTAATATGATTAAAGATACACAAAAAATATTATTACAGTATAAAAAAATGAAAAAACATTTCCGTAGAAATCCTGGA
CATATAACTAGTGAAAATTACTGGTAA

Upstream 100 bases:

>100_bases
TAATTGTATATATTTAAAATTAAAAAACAATATAATAATGAAAAACTATTTATAAAAATATTTTTATAATATAAGTATCT
TTATTCTGGAAAAATTTTAT

Downstream 100 bases:

>100_bases
TTTTTTAAAATTATATTTATTAAATATTCTTTAGGAATTGATTCCCGTACAATACAGGAATCAATTCCAAATACATGCAA
AAAAACAAAAATAATTTTTT

Product: Fpr

Products: NA

Alternate protein names: FNR; DA1; Flavodoxin reductase; FLDR; FLXR; Methyl viologen resistance protein A [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNPWLEIKLIAIKKWKNNLFSLIVQAPINKFIAGQFTKLSYIKKNKKRIQRAYSFVNSPNSKNLEFYILLIKNGLLTPKL
YDIKNNKIFISKNSFGFFTISELPKKENLWMIATGTAIGPYCSILKYENILKKFKKIILIHAVKYSIDLNYLNLFKKIKK
KYKKNIKIKIILSQEKRKDYLFGRIPNLIASGELEKSVKEPLNSKNSHVMLCGNPNMIKDTQKILLQYKKMKKHFRRNPG
HITSENYW

Sequences:

>Translated_248_residues
MNPWLEIKLIAIKKWKNNLFSLIVQAPINKFIAGQFTKLSYIKKNKKRIQRAYSFVNSPNSKNLEFYILLIKNGLLTPKL
YDIKNNKIFISKNSFGFFTISELPKKENLWMIATGTAIGPYCSILKYENILKKFKKIILIHAVKYSIDLNYLNLFKKIKK
KYKKNIKIKIILSQEKRKDYLFGRIPNLIASGELEKSVKEPLNSKNSHVMLCGNPNMIKDTQKILLQYKKMKKHFRRNPG
HITSENYW
>Mature_248_residues
MNPWLEIKLIAIKKWKNNLFSLIVQAPINKFIAGQFTKLSYIKKNKKRIQRAYSFVNSPNSKNLEFYILLIKNGLLTPKL
YDIKNNKIFISKNSFGFFTISELPKKENLWMIATGTAIGPYCSILKYENILKKFKKIILIHAVKYSIDLNYLNLFKKIKK
KYKKNIKIKIILSQEKRKDYLFGRIPNLIASGELEKSVKEPLNSKNSHVMLCGNPNMIKDTQKILLQYKKMKKHFRRNPG
HITSENYW

Specific function: Transports electrons between flavodoxin or ferredoxin and NADPH. Involved in the reductive activation of cobalamin- independent methionine synthase, pyruvate formate lyase and anaerobic ribonucleotide reductase. Also protects against superoxide radicals d

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790359, Length=249, Percent_Identity=46.5863453815261, Blast_Score=276, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 29207; Mature: 29207

Theoretical pI: Translated: 10.83; Mature: 10.83

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPWLEIKLIAIKKWKNNLFSLIVQAPINKFIAGQFTKLSYIKKNKKRIQRAYSFVNSPN
CCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
SKNLEFYILLIKNGLLTPKLYDIKNNKIFISKNSFGFFTISELPKKENLWMIATGTAIGP
CCCEEEEEEEEECCCCCCEEEEECCCEEEEEECCCCEEECCCCCCCCCEEEEEECCCCCH
YCSILKYENILKKFKKIILIHAVKYSIDLNYLNLFKKIKKKYKKNIKIKIILSQEKRKDY
HHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHH
LFGRIPNLIASGELEKSVKEPLNSKNSHVMLCGNPNMIKDTQKILLQYKKMKKHFRRNPG
HHHCCCHHHHCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
HITSENYW
CCCCCCCC
>Mature Secondary Structure
MNPWLEIKLIAIKKWKNNLFSLIVQAPINKFIAGQFTKLSYIKKNKKRIQRAYSFVNSPN
CCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
SKNLEFYILLIKNGLLTPKLYDIKNNKIFISKNSFGFFTISELPKKENLWMIATGTAIGP
CCCEEEEEEEEECCCCCCEEEEECCCEEEEEECCCCEEECCCCCCCCCEEEEEECCCCCH
YCSILKYENILKKFKKIILIHAVKYSIDLNYLNLFKKIKKKYKKNIKIKIILSQEKRKDY
HHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHH
LFGRIPNLIASGELEKSVKEPLNSKNSHVMLCGNPNMIKDTQKILLQYKKMKKHFRRNPG
HHHCCCHHHHCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
HITSENYW
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8449868; 8346018; 9278503; 1400248; 2834327; 7961651; 9149148 [H]