Click here to switch to the map view.

The map label for this gene is zwf [H]

Identifier: 116515135

GI number: 116515135

Start: 234325

End: 235785

Strand: Direct

Name: zwf [H]

Synonym: BCc_199

Alternate gene names: 116515135

Gene position: 234325-235785 (Clockwise)

Preceding gene: 116515133

Following gene: 116515136

Centisome position: 56.28

GC content: 17.11

Gene sequence:

>1461_bases
ATGAAATTACAAATGCATACACATGATTTAATTATTTTTGGAACTAAAGGTGATTTAGCTCAAAGAAAATTGTTTCCAGC
ATTATATTCGTTAGAAAAAAAAAATAAACTTGTAGATAATACACGAATTATTGGTGTTAGTAGATCAAATACTAATACAA
AAGAATATATTCAAATTATTTATAATGCATTAAAAAAATTTTTAAAAGAAAAAATAAATAAAAAAATATGGGAAAAATTC
AAAAAACGTTTTATTTTTTGTAAAATGAATATTAATTGTCTTCAAGATTTTAAAAAACTAAAAATAATACTAAAAAAAAA
AAAACATATATTACTTAATTATTTTGCAGTATCCTCAAATTTATTTATTAAAATTTGTAAAGGATTGTCTAATATTAATT
GTAATAGTAAAACATCAAAAATAATTATAGAAAAACCTATTGGTGATTCTTTAAAATCATTTAATTTTATTAATAAATCT
ATCAAAAAATATTTTTCAGAAAAACAAATATTTAGAATTGATCATTATTTAGGAAAAGAAGCATTATTAAATCTTATTAC
ATTAAAATTTTTTAATCCATTTTTTAATAATAATTTTAATAAAAAAACAATTGATCATATTCAAATAACATTATCTGAAA
GTCTAGGTATTGAAAAAAGATGGAGTTATTTTGATCAAACTGGACAAATTATAGATATGGTTCAAAATCATATGCTACAA
ATTATTTCTATTTTTGCTATGAATAAACCAAAATCATTAAAGAAAAAACATATTTGCTCTGAAAAAATAAAAATTTTAAA
ATCATTATATATTAAAAATAATGATATTAAAAATAATATATCATTAGGACAATATAAAAGTGGAAAAATTAATAATAATA
TTGTTCCATCATATGTGAATGAAGAAAATTCAAAAAAAAATAGTTTAACAGAAACTTTTGCAGCTATAAAATTATATATT
AATACAAAAAAATGGAAAAATGTTCCATTTTATATTCGTACTGGAAAAAGATTATTAAAAAAATGTTCTAAAATTATTAT
TTTTTTAAAAAAATCATCAGAAAACTTACTAAAAAATAATAAAAAAATATTTAATAATAGAATTATTATAAATTTACAAT
CACCTTTTAATATTAAAATAAAATTTTTTAATAAAATTCCTCAACTAAATTCAAAATTTAAATTAACTTCTAGTGAAATG
TTATTTAATTATAAAAAAATTACAAAAAATAATTTTTTTCCAGAAGAATATGAAAAATTATTATTAGAAAGTATGAAAGG
AAATCAATTTTTATTTGTTAATTACAAAGAAATTAAATATTCTTGGAAATGGATTGATTCTATAATAAAAATATATAAAA
AAAATCCATTATTACTCGAATATTATTCATCTGGTAGTTGGGGACCTAAATCATCAGAAAAATTAATAAAAAAAGATAAG
AGAAAATGGGATAATAATTAA

Upstream 100 bases:

>100_bases
TTACATATATATTTTAAAAATTTAATAAAATTAATATTTATAAAATAAAAAAAAATTTTTAAAATTCTTTAATTTTAATA
TTTTAATAATAGGGTTTAGT

Downstream 100 bases:

>100_bases
ATAATTATAAATATATTTTATATATATAGTTATTTAAAATTTTAAATATATTAATTTTTTTTATATAATACTTTTTATAT
ATAACAATAAAATTTTACAT

Product: hypothetical protein

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MKLQMHTHDLIIFGTKGDLAQRKLFPALYSLEKKNKLVDNTRIIGVSRSNTNTKEYIQIIYNALKKFLKEKINKKIWEKF
KKRFIFCKMNINCLQDFKKLKIILKKKKHILLNYFAVSSNLFIKICKGLSNINCNSKTSKIIIEKPIGDSLKSFNFINKS
IKKYFSEKQIFRIDHYLGKEALLNLITLKFFNPFFNNNFNKKTIDHIQITLSESLGIEKRWSYFDQTGQIIDMVQNHMLQ
IISIFAMNKPKSLKKKHICSEKIKILKSLYIKNNDIKNNISLGQYKSGKINNNIVPSYVNEENSKKNSLTETFAAIKLYI
NTKKWKNVPFYIRTGKRLLKKCSKIIIFLKKSSENLLKNNKKIFNNRIIINLQSPFNIKIKFFNKIPQLNSKFKLTSSEM
LFNYKKITKNNFFPEEYEKLLLESMKGNQFLFVNYKEIKYSWKWIDSIIKIYKKNPLLLEYYSSGSWGPKSSEKLIKKDK
RKWDNN

Sequences:

>Translated_486_residues
MKLQMHTHDLIIFGTKGDLAQRKLFPALYSLEKKNKLVDNTRIIGVSRSNTNTKEYIQIIYNALKKFLKEKINKKIWEKF
KKRFIFCKMNINCLQDFKKLKIILKKKKHILLNYFAVSSNLFIKICKGLSNINCNSKTSKIIIEKPIGDSLKSFNFINKS
IKKYFSEKQIFRIDHYLGKEALLNLITLKFFNPFFNNNFNKKTIDHIQITLSESLGIEKRWSYFDQTGQIIDMVQNHMLQ
IISIFAMNKPKSLKKKHICSEKIKILKSLYIKNNDIKNNISLGQYKSGKINNNIVPSYVNEENSKKNSLTETFAAIKLYI
NTKKWKNVPFYIRTGKRLLKKCSKIIIFLKKSSENLLKNNKKIFNNRIIINLQSPFNIKIKFFNKIPQLNSKFKLTSSEM
LFNYKKITKNNFFPEEYEKLLLESMKGNQFLFVNYKEIKYSWKWIDSIIKIYKKNPLLLEYYSSGSWGPKSSEKLIKKDK
RKWDNN
>Mature_486_residues
MKLQMHTHDLIIFGTKGDLAQRKLFPALYSLEKKNKLVDNTRIIGVSRSNTNTKEYIQIIYNALKKFLKEKINKKIWEKF
KKRFIFCKMNINCLQDFKKLKIILKKKKHILLNYFAVSSNLFIKICKGLSNINCNSKTSKIIIEKPIGDSLKSFNFINKS
IKKYFSEKQIFRIDHYLGKEALLNLITLKFFNPFFNNNFNKKTIDHIQITLSESLGIEKRWSYFDQTGQIIDMVQNHMLQ
IISIFAMNKPKSLKKKHICSEKIKILKSLYIKNNDIKNNISLGQYKSGKINNNIVPSYVNEENSKKNSLTETFAAIKLYI
NTKKWKNVPFYIRTGKRLLKKCSKIIIFLKKSSENLLKNNKKIFNNRIIINLQSPFNIKIKFFNKIPQLNSKFKLTSSEM
LFNYKKITKNNFFPEEYEKLLLESMKGNQFLFVNYKEIKYSWKWIDSIIKIYKKNPLLLEYYSSGSWGPKSSEKLIKKDK
RKWDNN

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI108773793, Length=487, Percent_Identity=30.3901437371663, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI109389365, Length=487, Percent_Identity=30.3901437371663, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI52145310, Length=378, Percent_Identity=24.6031746031746, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1788158, Length=477, Percent_Identity=42.1383647798742, Blast_Score=450, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17538218, Length=482, Percent_Identity=30.2904564315353, Blast_Score=225, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6324088, Length=480, Percent_Identity=32.0833333333333, Blast_Score=252, Evalue=9e-68,
Organism=Drosophila melanogaster, GI24643350, Length=479, Percent_Identity=30.2713987473904, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24643352, Length=479, Percent_Identity=30.2713987473904, Blast_Score=232, Evalue=4e-61,
Organism=Drosophila melanogaster, GI221513548, Length=486, Percent_Identity=25.3086419753086, Blast_Score=160, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 57616; Mature: 57616

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: PS00069 G6P_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLQMHTHDLIIFGTKGDLAQRKLFPALYSLEKKNKLVDNTRIIGVSRSNTNTKEYIQII
CEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHH
YNALKKFLKEKINKKIWEKFKKRFIFCKMNINCLQDFKKLKIILKKKKHILLNYFAVSSN
HHHHHHHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHHHHHHHHHHCHHEEEEEEEECCC
LFIKICKGLSNINCNSKTSKIIIEKPIGDSLKSFNFINKSIKKYFSEKQIFRIDHYLGKE
HHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHCHH
ALLNLITLKFFNPFFNNNFNKKTIDHIQITLSESLGIEKRWSYFDQTGQIIDMVQNHMLQ
HHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IISIFAMNKPKSLKKKHICSEKIKILKSLYIKNNDIKNNISLGQYKSGKINNNIVPSYVN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EENSKKNSLTETFAAIKLYINTKKWKNVPFYIRTGKRLLKKCSKIIIFLKKSSENLLKNN
CCCCCHHHHHHHHHHEEEEEECCCCCCCCEEEECHHHHHHHHHHEEEEEECCCCHHHHCC
KKIFNNRIIINLQSPFNIKIKFFNKIPQLNSKFKLTSSEMLFNYKKITKNNFFPEEYEKL
HHEECCEEEEEECCCCEEEEEEECCCCCCCCCEEECHHHHHHHHHHHHCCCCCHHHHHHH
LLESMKGNQFLFVNYKEIKYSWKWIDSIIKIYKKNPLLLEYYSSGSWGPKSSEKLIKKDK
HHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHH
RKWDNN
HHCCCC
>Mature Secondary Structure
MKLQMHTHDLIIFGTKGDLAQRKLFPALYSLEKKNKLVDNTRIIGVSRSNTNTKEYIQII
CEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHH
YNALKKFLKEKINKKIWEKFKKRFIFCKMNINCLQDFKKLKIILKKKKHILLNYFAVSSN
HHHHHHHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHHHHHHHHHHCHHEEEEEEEECCC
LFIKICKGLSNINCNSKTSKIIIEKPIGDSLKSFNFINKSIKKYFSEKQIFRIDHYLGKE
HHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHCHH
ALLNLITLKFFNPFFNNNFNKKTIDHIQITLSESLGIEKRWSYFDQTGQIIDMVQNHMLQ
HHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IISIFAMNKPKSLKKKHICSEKIKILKSLYIKNNDIKNNISLGQYKSGKINNNIVPSYVN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EENSKKNSLTETFAAIKLYINTKKWKNVPFYIRTGKRLLKKCSKIIIFLKKSSENLLKNN
CCCCCHHHHHHHHHHEEEEEECCCCCCCCEEEECHHHHHHHHHHEEEEEECCCCHHHHCC
KKIFNNRIIINLQSPFNIKIKFFNKIPQLNSKFKLTSSEMLFNYKKITKNNFFPEEYEKL
HHEECCEEEEEECCCCEEEEEEECCCCCCCCCEEECHHHHHHHHHHHHCCCCCHHHHHHH
LLESMKGNQFLFVNYKEIKYSWKWIDSIIKIYKKNPLLLEYYSSGSWGPKSSEKLIKKDK
HHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHH
RKWDNN
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]