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The map label for this gene is serC

Identifier: 116515128

GI number: 116515128

Start: 225626

End: 226714

Strand: Reverse

Name: serC

Synonym: BCc_192

Alternate gene names: 116515128

Gene position: 226714-225626 (Counterclockwise)

Preceding gene: 116515129

Following gene: 116515127

Centisome position: 54.45

GC content: 22.5

Gene sequence:

>1089_bases
ATGTCAAAAATTTATAATTTTAATCCTGGTCCAGCAATGCTGCCAAAAGAAGTTTTATTAGAAATAAAGAAAAATTTTCT
TAATTGGAATAATTCTGGATTTTCAATTACTGAAATTAGTCATCGTAGTTCTAGTTTTATTGAATTTACCATTCAAGTAG
AAAAAGATTTACGTAATTTATTACATATTCCAGAAAATTATAATATTTTATTTTCTCATGGAGGTGCTAGAGGACAATTT
TCTGCTATACCTATGAATTTAATTAAAAAATTTAAAAAACCAGACTATATCAATAGTGGTTATTGGTCGAAATGTGCTGC
TAAAGAAGCTAAAAAATATTGTGAACCAAATATTATTAATGTAAAAAGATATACAAAAAATAAACAGAAATATATTGAAT
CACCTATAAATTGGAAAATAACATCAAAACATACATATTTGCATTATTGTCCAAATGAAACTATTGAAGGAATAGAAATT
TTTGAAGAACCAATTTTATTGAACAAAATTATTATAGGAGATTTTTCTTCTACAATTTTATCTAGAAAAATCAATATAAA
AAAATATGGTATGATTTATGCATGTGCACAAAAAAATATTGGTCCTGCAGGAATTACAATAATTATTATTCGAAACGATT
TATTAATATCTTGTAAAAAAAAAATTCCATCTATTTTAGATTATCAATTATTATTTAAATCAAAATCTATGTTAAATACT
CCTAGTATTTTTTCATGGTATGTTTCAGGATTAGTATTTAAATGGATAAAAAATTTAGGTGGTTTAAATGTTATTGAGAA
AAAAAATATAAAAAAAGCAAAAATTTTATATAAATATTTAAACTCTACAAATTTTTATTATAACTGTATTCTACCTTCTA
ATCAATCACGAATGAATGTAACATTTAATTTATACAAGAATGAATTAACTAATTTTTTTATTCAAGAATCTGAAAAATCT
GGATTATATGGTTTAAAAGGACATTCAATAATTGGAGGCTTAAGAGCATCTATATATAACGCAATGCCGATAGAAGGTGT
AAAAAAACTTATTCAATTTATGAAAAATTTTGAAAAAAAATTTGGTTAA

Upstream 100 bases:

>100_bases
TTATAATAATATTTATAAATATTTTTTTAAAAAATAATATTATTTATATGATGAATTATTAATCATATTTAATATATAAA
TATTAATATTGGTAATTAAT

Downstream 100 bases:

>100_bases
AATTATGTAAAAAAATAACTACATTTTTGATTTTTATAAATTTTTATTTATAGGATTATTTAAATAATGCAAGATAGTTT
AACTTTAAAACCAGTAGATT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSKIYNFNPGPAMLPKEVLLEIKKNFLNWNNSGFSITEISHRSSSFIEFTIQVEKDLRNLLHIPENYNILFSHGGARGQF
SAIPMNLIKKFKKPDYINSGYWSKCAAKEAKKYCEPNIINVKRYTKNKQKYIESPINWKITSKHTYLHYCPNETIEGIEI
FEEPILLNKIIIGDFSSTILSRKINIKKYGMIYACAQKNIGPAGITIIIIRNDLLISCKKKIPSILDYQLLFKSKSMLNT
PSIFSWYVSGLVFKWIKNLGGLNVIEKKNIKKAKILYKYLNSTNFYYNCILPSNQSRMNVTFNLYKNELTNFFIQESEKS
GLYGLKGHSIIGGLRASIYNAMPIEGVKKLIQFMKNFEKKFG

Sequences:

>Translated_362_residues
MSKIYNFNPGPAMLPKEVLLEIKKNFLNWNNSGFSITEISHRSSSFIEFTIQVEKDLRNLLHIPENYNILFSHGGARGQF
SAIPMNLIKKFKKPDYINSGYWSKCAAKEAKKYCEPNIINVKRYTKNKQKYIESPINWKITSKHTYLHYCPNETIEGIEI
FEEPILLNKIIIGDFSSTILSRKINIKKYGMIYACAQKNIGPAGITIIIIRNDLLISCKKKIPSILDYQLLFKSKSMLNT
PSIFSWYVSGLVFKWIKNLGGLNVIEKKNIKKAKILYKYLNSTNFYYNCILPSNQSRMNVTFNLYKNELTNFFIQESEKS
GLYGLKGHSIIGGLRASIYNAMPIEGVKKLIQFMKNFEKKFG
>Mature_361_residues
SKIYNFNPGPAMLPKEVLLEIKKNFLNWNNSGFSITEISHRSSSFIEFTIQVEKDLRNLLHIPENYNILFSHGGARGQFS
AIPMNLIKKFKKPDYINSGYWSKCAAKEAKKYCEPNIINVKRYTKNKQKYIESPINWKITSKHTYLHYCPNETIEGIEIF
EEPILLNKIIIGDFSSTILSRKINIKKYGMIYACAQKNIGPAGITIIIIRNDLLISCKKKIPSILDYQLLFKSKSMLNTP
SIFSWYVSGLVFKWIKNLGGLNVIEKKNIKKAKILYKYLNSTNFYYNCILPSNQSRMNVTFNLYKNELTNFFIQESEKSG
LYGLKGHSIIGGLRASIYNAMPIEGVKKLIQFMKNFEKKFG

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily

Homologues:

Organism=Homo sapiens, GI17402893, Length=364, Percent_Identity=41.4835164835165, Blast_Score=299, Evalue=3e-81,
Organism=Homo sapiens, GI10863955, Length=360, Percent_Identity=39.1666666666667, Blast_Score=261, Evalue=7e-70,
Organism=Escherichia coli, GI1787136, Length=363, Percent_Identity=49.5867768595041, Blast_Score=406, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17506897, Length=362, Percent_Identity=39.2265193370166, Blast_Score=266, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6324758, Length=384, Percent_Identity=38.0208333333333, Blast_Score=233, Evalue=3e-62,
Organism=Drosophila melanogaster, GI21356589, Length=364, Percent_Identity=42.3076923076923, Blast_Score=294, Evalue=7e-80,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SERC_BUCCC (Q057N5)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802757.1
- ProteinModelPortal:   Q057N5
- SMR:   Q057N5
- STRING:   Q057N5
- EnsemblBacteria:   EBBUCT00000001226
- GeneID:   4440686
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_192
- eggNOG:   COG1932
- GeneTree:   EBGT00050000007909
- HOGENOM:   HBG289982
- OMA:   TFAWYLA
- ProtClustDB:   PRK05355
- BioCyc:   BAPH372461:BCC_192-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00160
- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PIRSF:   PIRSF000525
- TIGRFAMs:   TIGR01364

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.52

Molecular weight: Translated: 41794; Mature: 41662

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: BINDING 42-42 BINDING 102-102 BINDING 154-154 BINDING 174-174 BINDING 197-197

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIYNFNPGPAMLPKEVLLEIKKNFLNWNNSGFSITEISHRSSSFIEFTIQVEKDLRNL
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEEEHHHHHHH
LHIPENYNILFSHGGARGQFSAIPMNLIKKFKKPDYINSGYWSKCAAKEAKKYCEPNIIN
HCCCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEE
VKRYTKNKQKYIESPINWKITSKHTYLHYCPNETIEGIEIFEEPILLNKIIIGDFSSTIL
EHHHHCCHHHHHCCCCCEEEECCEEEEEECCCCCCCHHHHHHCCHHHHEEEECCHHHHHH
SRKINIKKYGMIYACAQKNIGPAGITIIIIRNDLLISCKKKIPSILDYQLLFKSKSMLNT
HHCCCEECCCEEEEEECCCCCCCCEEEEEEECCEEEEEHHHCCHHHHHHHHHHCHHHCCC
PSIFSWYVSGLVFKWIKNLGGLNVIEKKNIKKAKILYKYLNSTNFYYNCILPSNQSRMNV
CHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEE
TFNLYKNELTNFFIQESEKSGLYGLKGHSIIGGLRASIYNAMPIEGVKKLIQFMKNFEKK
EEEEEHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FG
CC
>Mature Secondary Structure 
SKIYNFNPGPAMLPKEVLLEIKKNFLNWNNSGFSITEISHRSSSFIEFTIQVEKDLRNL
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEEEHHHHHHH
LHIPENYNILFSHGGARGQFSAIPMNLIKKFKKPDYINSGYWSKCAAKEAKKYCEPNIIN
HCCCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEE
VKRYTKNKQKYIESPINWKITSKHTYLHYCPNETIEGIEIFEEPILLNKIIIGDFSSTIL
EHHHHCCHHHHHCCCCCEEEECCEEEEEECCCCCCCHHHHHHCCHHHHEEEECCHHHHHH
SRKINIKKYGMIYACAQKNIGPAGITIIIIRNDLLISCKKKIPSILDYQLLFKSKSMLNT
HHCCCEECCCEEEEEECCCCCCCCEEEEEEECCEEEEEHHHCCHHHHHHHHHHCHHHCCC
PSIFSWYVSGLVFKWIKNLGGLNVIEKKNIKKAKILYKYLNSTNFYYNCILPSNQSRMNV
CHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEE
TFNLYKNELTNFFIQESEKSGLYGLKGHSIIGGLRASIYNAMPIEGVKKLIQFMKNFEKK
EEEEEHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA