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The map label for this gene is yabC

Identifier: 116515077

GI number: 116515077

Start: 161767

End: 162690

Strand: Reverse

Name: yabC

Synonym: BCc_137

Alternate gene names: 116515077

Gene position: 162690-161767 (Counterclockwise)

Preceding gene: 116515078

Following gene: 116515076

Centisome position: 39.07

GC content: 20.56

Gene sequence:

>924_bases
ATGTCACATATACCTGTATTACTTAAAGAAACAATTAATGCTTTAAATATTAAGAAAAATGGCATATATATTGATGGAAC
ATTTGGAAACGGAGGACATACAAAAGAAATATTAAAGTATTTAGGACAATCTGGTAAACTATATTCTATTGATCAAGATA
TTAAATCAGTAAATAAAGGAAAAAAAATAAAAGACAAGAGATTTTCTATAATATTTGGAAAATTTTCTAAAAAAATACCT
TATATATATAAAAAAAATAAAAAAAAAAAAATTGATGGAATTTTATTAGATTTAGGAATTTCATCAAATCAAATTAATCA
AAATGATAGAGGTTTTTCATTTATGAAAAACGGACTATTAGATATGCGTATGAACAATACAACAGGTATACCAGCTTGGA
AATGGCTTAAAAAATCTAGTCAAAAAGAAATAGAGAAAGTGCTAAGAAAATATGGAGAAGAAAGATATTCTAAAAAAATT
TCTTATGCTATCTATAATAGAAATAAAAAAAAAACAATAACTCAAACATTAGATTTAGTACAAATTATAAAAAAAGCAAT
TCCAAAAATAGATAAATATAAACATCCGGCAACAAGAACTTTTCAAGCTATACGTATTCATATAAATAATGAAATTAAAG
AATTAAAAAAAACATTAAAAATATCAATAAAGATATTAAAAAAAAAAAGAAGATTAGTTATTATTTGTTTTCATTCTCTT
GAAAATAGAATAGTAAAAAATTTTTTTAAAAAACATGGTAAAACTTTTTTTATACCAAGAGGATTACCTATTACCGAAAA
AAAAATCAAAAAAATTGAAAATAAAAAAATAAAAATTATCAAAAAAATTAAACCTAAAAAAACTGAAATTCAAAAAAATA
AAAGATCTAGAAGTGCAATATTAAGAATTGCAGAAATGTTATAA

Upstream 100 bases:

>100_bases
AACAAAACTTTTATACATTTTCTATTAAATTTTAAAAATTATTTTTTAAAATAATTTCTTTAGAGAATGTATAGAATTAA
ATTCTAATAAATATAAAATT

Downstream 100 bases:

>100_bases
TAAATATTTTTTTTAAAAAAAATATTAGACAATATTTATATTGTAAATAAATTAAAAAAAAATATATTTTTATCTTAATT
AAGATATATAATTTATTTTT

Product: S-adenosyl-dependent methyl transferase

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSHIPVLLKETINALNIKKNGIYIDGTFGNGGHTKEILKYLGQSGKLYSIDQDIKSVNKGKKIKDKRFSIIFGKFSKKIP
YIYKKNKKKKIDGILLDLGISSNQINQNDRGFSFMKNGLLDMRMNNTTGIPAWKWLKKSSQKEIEKVLRKYGEERYSKKI
SYAIYNRNKKKTITQTLDLVQIIKKAIPKIDKYKHPATRTFQAIRIHINNEIKELKKTLKISIKILKKKRRLVIICFHSL
ENRIVKNFFKKHGKTFFIPRGLPITEKKIKKIENKKIKIIKKIKPKKTEIQKNKRSRSAILRIAEML

Sequences:

>Translated_307_residues
MSHIPVLLKETINALNIKKNGIYIDGTFGNGGHTKEILKYLGQSGKLYSIDQDIKSVNKGKKIKDKRFSIIFGKFSKKIP
YIYKKNKKKKIDGILLDLGISSNQINQNDRGFSFMKNGLLDMRMNNTTGIPAWKWLKKSSQKEIEKVLRKYGEERYSKKI
SYAIYNRNKKKTITQTLDLVQIIKKAIPKIDKYKHPATRTFQAIRIHINNEIKELKKTLKISIKILKKKRRLVIICFHSL
ENRIVKNFFKKHGKTFFIPRGLPITEKKIKKIENKKIKIIKKIKPKKTEIQKNKRSRSAILRIAEML
>Mature_306_residues
SHIPVLLKETINALNIKKNGIYIDGTFGNGGHTKEILKYLGQSGKLYSIDQDIKSVNKGKKIKDKRFSIIFGKFSKKIPY
IYKKNKKKKIDGILLDLGISSNQINQNDRGFSFMKNGLLDMRMNNTTGIPAWKWLKKSSQKEIEKVLRKYGEERYSKKIS
YAIYNRNKKKTITQTLDLVQIIKKAIPKIDKYKHPATRTFQAIRIHINNEIKELKKTLKISIKILKKKRRLVIICFHSLE
NRIVKNFFKKHGKTFFIPRGLPITEKKIKKIENKKIKIIKKIKPKKTEIQKNKRSRSAILRIAEML

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=344, Percent_Identity=33.1395348837209, Blast_Score=181, Evalue=7e-46,
Organism=Homo sapiens, GI165377202, Length=191, Percent_Identity=35.6020942408377, Blast_Score=119, Evalue=5e-27,
Organism=Escherichia coli, GI1786270, Length=303, Percent_Identity=48.1848184818482, Blast_Score=329, Evalue=2e-91,
Organism=Drosophila melanogaster, GI62472493, Length=328, Percent_Identity=35.3658536585366, Blast_Score=171, Evalue=6e-43,
Organism=Drosophila melanogaster, GI28571637, Length=328, Percent_Identity=35.3658536585366, Blast_Score=171, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_BUCCC (Q057T6)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802706.1
- ProteinModelPortal:   Q057T6
- SMR:   Q057T6
- STRING:   Q057T6
- EnsemblBacteria:   EBBUCT00000001426
- GeneID:   4440878
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_137
- eggNOG:   COG0275
- GeneTree:   EBGT00050000007757
- HOGENOM:   HBG302779
- OMA:   RQKVIQK
- BioCyc:   BAPH372461:BCC_137-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 35909; Mature: 35777

Theoretical pI: Translated: 11.15; Mature: 11.15

Prosite motif: NA

Important sites: BINDING 51-51 BINDING 83-83 BINDING 97-97 BINDING 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHIPVLLKETINALNIKKNGIYIDGTFGNGGHTKEILKYLGQSGKLYSIDQDIKSVNKG
CCCCCHHHHHHHHHHEEECCCEEEEECCCCCCCHHHHHHHHCCCCCEEECHHHHHHHHCC
KKIKDKRFSIIFGKFSKKIPYIYKKNKKKKIDGILLDLGISSNQINQNDRGFSFMKNGLL
CCCCCCHHEEEEECHHCCCCCCEECCCCHHHCEEEEEECCCCCCCCCCCCCHHHHHCCCE
DMRMNNTTGIPAWKWLKKSSQKEIEKVLRKYGEERYSKKISYAIYNRNKKKTITQTLDLV
EEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHH
QIIKKAIPKIDKYKHPATRTFQAIRIHINNEIKELKKTLKISIKILKKKRRLVIICFHSL
HHHHHHCCHHHHCCCCCHHHEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHH
ENRIVKNFFKKHGKTFFIPRGLPITEKKIKKIENKKIKIIKKIKPKKTEIQKNKRSRSAI
HHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHH
LRIAEML
HHHHHHC
>Mature Secondary Structure 
SHIPVLLKETINALNIKKNGIYIDGTFGNGGHTKEILKYLGQSGKLYSIDQDIKSVNKG
CCCCHHHHHHHHHHEEECCCEEEEECCCCCCCHHHHHHHHCCCCCEEECHHHHHHHHCC
KKIKDKRFSIIFGKFSKKIPYIYKKNKKKKIDGILLDLGISSNQINQNDRGFSFMKNGLL
CCCCCCHHEEEEECHHCCCCCCEECCCCHHHCEEEEEECCCCCCCCCCCCCHHHHHCCCE
DMRMNNTTGIPAWKWLKKSSQKEIEKVLRKYGEERYSKKISYAIYNRNKKKTITQTLDLV
EEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHH
QIIKKAIPKIDKYKHPATRTFQAIRIHINNEIKELKKTLKISIKILKKKRRLVIICFHSL
HHHHHHCCHHHHCCCCCHHHEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHH
ENRIVKNFFKKHGKTFFIPRGLPITEKKIKKIENKKIKIIKKIKPKKTEIQKNKRSRSAI
HHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHH
LRIAEML
HHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA