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The map label for this gene is nuoL [H]

Identifier: 116515048

GI number: 116515048

Start: 121241

End: 123106

Strand: Direct

Name: nuoL [H]

Synonym: BCc_107

Alternate gene names: 116515048

Gene position: 121241-123106 (Clockwise)

Preceding gene: 116515047

Following gene: 116515049

Centisome position: 29.12

GC content: 16.08

Gene sequence:

>1866_bases
ATGAATTTAATTTTTTATATTGTTTTATTTCCATTATTAAGTTTTTTTTTATTGTTTTTTTTTCAGAATTTTTTTTCAAA
AAAAAATATTTCAATGATTTGTATTTTTTCTCTTATAGTTTCGTTTGTTTTTTATTTATATGTTTTTTATAATTATTATA
AAAATAATGTTTTTAAAGTTTTTTTTATTTCAGTATGTAATTGGATTACTTTAAATAATTATAATATTAAATTAAAATTC
TTAATAGATATTTTTTCTTTAACTATGTTAGGAATATTACAATTAATAAGTTTATGTGTTTTTATTTTTTCATTATGGTA
TATGAAAAAATCTCAAGAATATAAAAAATATTTTTTATATATGAATCTATTTGTTTTTTTTATGATGATATTTTTATTAA
CTTCAAATTTTTTAAGTATGTTTTTTGTTTGGGAATTAGTCGGACTTTGTTCTTATTTATTAATTGGTTTTTATTATAAA
AAAAAAAAAAATGGATATGCAGCTATTAAATCATTTTTAATGACTAGAATAAGTGATTTATTTTTTTTGATTGCTATTTT
TTTAATTTTTTTAAAATTTAATACACTAGATTTTTTTGTATTAAAATATTATTTAAAAGAAATTATTTTTTTAAATAATT
ATACTAATGATTTGTTTTGGATTACTTTTTTTTTAACAATTGCAGTAATAGGTAAATCAGCACAAGTTCCTCTTCATACT
TGGTTAACAGGAGCTATGGTAGGTCCAACTCCAGCTTCAGCATTAATTCATGCAGCTACTATGGTAACTATGGGTATTTA
TTTAATTATTCGTGTAAATTTTTTATTTTTTTCTTGCATAGAAATAATGAAATTATTTCTTATAATAGGTAGTATTACAA
TTTTAATATCAAGTATTTCAGCTATTTATGAAAAAAATATTAAATGTATTTTAGCATATTCTACTATGAGTCAAATTGGT
TATATGTTATTAGCATTAGGAACAAAAAATATTTTTGGTGCTTTTTTTCATTTAATTATTCATGCATTTTTTAAATCTTT
ATTATTTTTATCTGCTGGATCTATTATAAAGTATACAAATAATGAATTTAATATTTTTAAGATGGGTTGTAGATATCAAG
AAGTACCTTTTTTATATATCTTATTTTTAATATGTTGTTTTTCTTTAATGTCTTTTCCTTTAATTACTTCGGGTTATTAT
AGTAAAAAAAACATTTTATTTTATATTTATAATCAAAAAAATTATTTAGTTTTATTCATGTTTTTTTTAGGAGTATTTTT
TACATCAATATATTCTATGAGAATGATATTTGTTATTTTTCATAATATTAATAAAAAAAAATATTTATATATAAAAAAAA
ATTTTTTTTATAATTTTTCTTTATTTGTATTGTTTTTAGGATGTACTCCACTTACTTGGTATTTATTTTATAATATTTTT
TCTAAGTATTTTATTTTATCTAACCATATTTGTGCTGAATCTTTATATATTGAATATATTTCTTTTTGTTGTTCGTTATT
AGGATTAATCTATTCATATTTTATGTATTATAAAAAAGATTTTTCTTCAAAGAATAATTTCTTTAAAAGTATTTTTTATC
CAATATATATTTTAATAAATAATTCTTGGTATTTTGATATTTTTTATTTTTATATTTTTATTCAATCATACTGTAATATA
TCTCAATATATAAATAATAAAAATTTTTTTTATATAGAAAATTTCTTTTTAAATAAAAAAAAATTTTTTAAAAAAAAAAT
ATTTAAAATTAATATTGTTGATATTGTATATCATATTAGATGGTATATTTTTTGTTTATTTTCAGTTTTATTAATTATTT
TTATAAATATAAATTATTATTATTAA

Upstream 100 bases:

>100_bases
CCATAGCTACAGTAGAAGTTAGTGTAATGCTAGCAATTTTTTTAAGAATATATCAACGTTATCATACATTAGATATATAT
AAATTAAGAGAGATTTCTAA

Downstream 100 bases:

>100_bases
TATTTTATTAATTATATTTAATAAGGATTATATATTATATGATATTACTTATATTAGTTTTAATACCTATTTTTGGTGCG
ATATTATCATGTTTAATGTT

Product: NADH dehydrogenase I chain L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MNLIFYIVLFPLLSFFLLFFFQNFFSKKNISMICIFSLIVSFVFYLYVFYNYYKNNVFKVFFISVCNWITLNNYNIKLKF
LIDIFSLTMLGILQLISLCVFIFSLWYMKKSQEYKKYFLYMNLFVFFMMIFLLTSNFLSMFFVWELVGLCSYLLIGFYYK
KKKNGYAAIKSFLMTRISDLFFLIAIFLIFLKFNTLDFFVLKYYLKEIIFLNNYTNDLFWITFFLTIAVIGKSAQVPLHT
WLTGAMVGPTPASALIHAATMVTMGIYLIIRVNFLFFSCIEIMKLFLIIGSITILISSISAIYEKNIKCILAYSTMSQIG
YMLLALGTKNIFGAFFHLIIHAFFKSLLFLSAGSIIKYTNNEFNIFKMGCRYQEVPFLYILFLICCFSLMSFPLITSGYY
SKKNILFYIYNQKNYLVLFMFFLGVFFTSIYSMRMIFVIFHNINKKKYLYIKKNFFYNFSLFVLFLGCTPLTWYLFYNIF
SKYFILSNHICAESLYIEYISFCCSLLGLIYSYFMYYKKDFSSKNNFFKSIFYPIYILINNSWYFDIFYFYIFIQSYCNI
SQYINNKNFFYIENFFLNKKKFFKKKIFKINIVDIVYHIRWYIFCLFSVLLIIFININYYY

Sequences:

>Translated_621_residues
MNLIFYIVLFPLLSFFLLFFFQNFFSKKNISMICIFSLIVSFVFYLYVFYNYYKNNVFKVFFISVCNWITLNNYNIKLKF
LIDIFSLTMLGILQLISLCVFIFSLWYMKKSQEYKKYFLYMNLFVFFMMIFLLTSNFLSMFFVWELVGLCSYLLIGFYYK
KKKNGYAAIKSFLMTRISDLFFLIAIFLIFLKFNTLDFFVLKYYLKEIIFLNNYTNDLFWITFFLTIAVIGKSAQVPLHT
WLTGAMVGPTPASALIHAATMVTMGIYLIIRVNFLFFSCIEIMKLFLIIGSITILISSISAIYEKNIKCILAYSTMSQIG
YMLLALGTKNIFGAFFHLIIHAFFKSLLFLSAGSIIKYTNNEFNIFKMGCRYQEVPFLYILFLICCFSLMSFPLITSGYY
SKKNILFYIYNQKNYLVLFMFFLGVFFTSIYSMRMIFVIFHNINKKKYLYIKKNFFYNFSLFVLFLGCTPLTWYLFYNIF
SKYFILSNHICAESLYIEYISFCCSLLGLIYSYFMYYKKDFSSKNNFFKSIFYPIYILINNSWYFDIFYFYIFIQSYCNI
SQYINNKNFFYIENFFLNKKKFFKKKIFKINIVDIVYHIRWYIFCLFSVLLIIFININYYY
>Mature_621_residues
MNLIFYIVLFPLLSFFLLFFFQNFFSKKNISMICIFSLIVSFVFYLYVFYNYYKNNVFKVFFISVCNWITLNNYNIKLKF
LIDIFSLTMLGILQLISLCVFIFSLWYMKKSQEYKKYFLYMNLFVFFMMIFLLTSNFLSMFFVWELVGLCSYLLIGFYYK
KKKNGYAAIKSFLMTRISDLFFLIAIFLIFLKFNTLDFFVLKYYLKEIIFLNNYTNDLFWITFFLTIAVIGKSAQVPLHT
WLTGAMVGPTPASALIHAATMVTMGIYLIIRVNFLFFSCIEIMKLFLIIGSITILISSISAIYEKNIKCILAYSTMSQIG
YMLLALGTKNIFGAFFHLIIHAFFKSLLFLSAGSIIKYTNNEFNIFKMGCRYQEVPFLYILFLICCFSLMSFPLITSGYY
SKKNILFYIYNQKNYLVLFMFFLGVFFTSIYSMRMIFVIFHNINKKKYLYIKKNFFYNFSLFVLFLGCTPLTWYLFYNIF
SKYFILSNHICAESLYIEYISFCCSLLGLIYSYFMYYKKDFSSKNNFFKSIFYPIYILINNSWYFDIFYFYIFIQSYCNI
SQYINNKNFFYIENFFLNKKKFFKKKIFKINIVDIVYHIRWYIFCLFSVLLIIFININYYY

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=472, Percent_Identity=32.4152542372881, Blast_Score=224, Evalue=1e-58,
Organism=Escherichia coli, GI1788614, Length=626, Percent_Identity=33.0670926517572, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1788829, Length=427, Percent_Identity=25.9953161592506, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1788827, Length=313, Percent_Identity=27.7955271565495, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1788613, Length=488, Percent_Identity=24.3852459016393, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788831, Length=334, Percent_Identity=25.1497005988024, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI2367154, Length=375, Percent_Identity=23.4666666666667, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI145693160, Length=251, Percent_Identity=27.0916334661355, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 74824; Mature: 74824

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]