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The map label for this gene is rpoC

Identifier: 116514967

GI number: 116514967

Start: 19824

End: 24056

Strand: Reverse

Name: rpoC

Synonym: BCc_018

Alternate gene names: 116514967

Gene position: 24056-19824 (Counterclockwise)

Preceding gene: 116514968

Following gene: 116514963

Centisome position: 5.78

GC content: 28.37

Gene sequence:

>4233_bases
ATGAAAGATATATTAAAACTTTTTAAAAAAAATAAAAAAGTAGAAGAATTTGATTCTATTAAAATTTCGTTAGCATCACC
TGAAGTTATACGATCATGGTCTTTTGGAGAAGTTAAAAAACCTGAAACAATAAACTATAGAACTTTAAACCCAGAACGTG
ATGGATTATTTTGCGCTCGTATATTCGGTCCAATAAAAGATTATGAATGCCTATGCGGTAAATATAAACGATTAAAACAT
AGAGGTGTAATATGCGAAAAATGCGGTGTTGAAGTTACACAAAGCAAAGTTAGAAGAGACAGGATGGGTCATATTGAATT
AGCTGCTCCAATAGCTCATATCTGGTTTTTAAAATCATTACCTTCAAGAATCGGACTATTATTAGATATGCCTTTAAGAG
ATATTGAAAGAGTTTTATATTTTGAATCTTATGTTATAACTGATCCAGGAATAACTAATTTAGAAAAATATCAAGTATTA
TCAGAAGATCAATATATTCAGGCTTTAGAAGAAAATGAAGATGAATTTGAAGCAAAAATGGGAGCTGAAGCTATACAAAA
TCTTTTAAAAAATATGGATTTAAAAAAAACATGTAAAATTCTTAAAAAAGAAGTGTTAAAAGTCAATTCAGAAACAAAAA
GAAAAAAAGTAACAAAACGAATAAAATTAATAGAATCACTATTAACTTCAAAAAATAAACCGGAATGGATGATTCTAACA
GTATTACCAATATTACCACCAGATTTAAGACCATTAGTACCATTAGACGGAGGAAGATTTGCAACATCAGATTTAAATGA
TCTATATCGAAGAGTTATAAATAGAAATAACAGATTAAAACGTTTATTAGAATTATTTGCTCCTGAAATTATTGTGAGAA
ACGAAAAAAGAATGCTCCAAGAAGCTATTGATGCATTATTAGATAATGGTCGAAGAGGCAGATCAATAACGGGATCAAAT
AAAAGACCGTTAAAATCTTTAGCTGATATGATTAAAGGAAAACAAGGTAGATTTAGACAAAATTTATTAGGAAAAAGAGT
AGATTATTCTGGAAGATCTGTTATCACTGTAGGTCCGTATTTACATTTAAATCAATGCGGAATACCTAAAAAAATGGCTT
TAGAATTATTTAAACCTTTTATATATGGAAAATTAGAGCAAAGAAATTTAGCTACAACAATTAAATCTGCTAAAAAAATG
GTGGAGAAGGAAGAACCTATAGTGTGGGATATACTAGATGAAGTAATTCATAAACATCCAATATTATTAAATCGAGCTCC
TACATTACATCGATTAGGAATACAAGCTTTTGAACCAATTCTAATTGAAGGAAAAGCTATACAACTACATCCTTTAGTAT
GTGCAGCTTATAATGCGGATTTTGATGGTGATCAAATGGCTATTCATATACCTTTAACTAAAACAGCACAAAAAGAAGCA
TGTTCCTTAATGATGTCAACAAAAAATATACTTTCTCCTGCTAATGGAGAACCAATTATTGTTCCATCTCAAGACGTAGT
TCTTGGAATATATTATATGACAAGAAAAAAAATTAATGGAAAAGGCGAAAATATGTTGCTATCAAGTCCTAAAGAAGCTG
AGTATATGTACTCCCTCGGAGCCGTAGATTTGCATTCTATTGTTAAAATCCGCATATTAGAATATAAAAAGGATGAAAAA
AAAAATTTAACTGAAAAAAAAAAAATAATCAAAACAACTATTGGAAGAGCTATTCTTTGGATTCATGTTCCAATGGGATT
ACCTTTTAAAATTTTTAATAAAACATTAAGAAAATCTCATATATCTGAAATTTTAAATACATGTTATAGATTATTAGGAC
TTAAAAAAACAGTACGATTAGCGGATCAAATGATGTATATAGGATTTTCATATGCAGCTAAATCTGGAGTATCAGTTGGA
ATTAATGACATAATAATTCCTAAAGAAAAAGAAAAAATTATATTTCAAGCTGAAAAAGAAGTATTAGAAATAGATAAACA
GTTTCAAACTGGACTAGTAACTTCTAGTGAAAGATATAATAAAGTTATTGATATCTGGGCAATAGCTAATGAAAATATTG
CTGATGCTATGATGAAAAATTTATCTTATGAAATTATTTTTCAAAAAAACAAAAAAAAAATAACACAAAAATCTTTTAAC
AATATTTTTATTATGGCAGATTCTGGAGCAAGAGGATCGGCAGCTCAAATTAGACAATTAGCGGGTATGCGTGGATTAAT
GGCAAAACCAGATGGTTCAATAATAGAAACACCAATAACAGCGAATTTTAGAGAAGGACTAAATGTTTTACAATATTTTA
TTTCAACACATGGGGCGAGAAAAGGATTAGCTGATACAGCATTAAAAACAGCTAATTCAGGATACTTAACTAGAAGATTA
GTAGATGTTGCTCAAGATTTAGTAATTACACAAACTAACTGTAAAACTAAAAAAGGAATTTTAATGAATTCTTTAATTGA
AGGGGGTGATATTAAAGAAACGTTAAAAGAAAGAGTTTTAGGAAGAATTACAGTTGAAAATATTTATCATTTAAATTCTA
AAAATATCATAATACCAAAAAATACATTATTAAATGAAAAATGGTGCAATATTTTAGAAAAAAATTTTATTGATTCAATT
ATTGTAAGATCTGTAGTACATTGTGAAACAAGTTTTGGTGTCTGTGCTTATTGTTACGGACGTGATTTAGCACGAGGTAA
AATAGTTAAAAAAGGTGAAGCTGTGGGAGTTATAGCTGCACAATCGATTGGAGAACCCGGAACTCAATTAACTATGCGAA
CATTTCATATTGGAGGAGCAGCTTCAAAAGTAGCATCAGAATCAAGTATACAAATTCGAAAAAACGGAATTATTCATTTA
AATCAAGCAAAATCAGTAATAAATTCTAATGGAAAAATTGTTATTATTTCACGAAATGTTGAATTAAAAATGTTAGATAA
AACAGGAAAAACACAGGAAAGTTATAAAATTCCATATGGATCAATATTAACTAAAGGAGAAGGTCAAAAAGTTAAAGCAG
GGGAAATAATTGCAAAATGGGATCCACATACTATTCCAGTTATTACTGAAGTTAATGGATATATAAAATTTATTGATATG
GTTGATGGAAAAAGTATTACTAAACAAAATGATGAACTAACAGGATTATCTTCTATTGTTGTATTAGATATTTCTGAGAG
AAATATACTAGGAAAAGATTTAAAACCAGCATTAAAGATTATAGGTAAAAATGAGGAAGATATCTTTATTCCTGGAACAG
ATATGCCAGCACAATATTTTCTTCCTGGAAAATCAATTATTTTATTAGAAGATGGTATGAAAATTTCTTCTGGAGATATT
TTAGCTCGTGTTCCACAAGAATCAGTAGGAACAAAAGACATTACTGGAGGATTACCTAGAGTAGCAGATCTATTTGAAGC
TCGAAAACCAAAAGAATTGGCTATTCTAGCAGAAATAAATGGTATAGTTTCTTTTGGAAAAGAAACAAAAGGAAAAAGAA
GATTAATTCTAACTCCAATAGATGGAAATAACATTTATGAAGAAATGATTCCTAAATGGAGACAATTAAATGTTTTTGAA
GGAGAAAGAGTAGAAAAAGGAGATATAATTTCAGATGGACCAGAATCACCACATGATATCTTACGATTAAGAGGAGTGCA
AGCTGTTACAAACTATATTGTAAATGAAGTTCAAGAAGTTTATCGTTTACAAGGAGTTAAAATTAATGATAAACATATCG
AAGTTATTATCAGGCAAATGTTAAGAAAAGCAACAATAATAAATCCAGGTGATTCTAATTTTTTACAAGGAGAACAAATA
GAATATTCAAAAATCACATCAGAAAATAAAAAACTAAAAAAAAATAAAAAAGAAACAGCAACATTTTCTCGTGATTTATT
AGGTATTACTAAAGCATCATTAGCTACAGAATCATTTATTTCTGCTGCATCATTTCAAGAAACTACTAGAGTATTAACAG
AAGCAGCTGTAGCTGGAAAAAAAGATAAGCTAAGAGGATTAAAAGAAAATGTAATTGTTGGTAGATTAATTCCTGCGGGA
ACTGGATATAAATATCATAAAAAAAGATTAAAAAATAGAATAAAAAATTCTGTCAATAAAAAAAACAACATGAGTTCTAT
TAGTGTAGAAGAAGCTGCGGCTAATTTATCTGAATTATTAAATTCAACAGAAAACATAAATAATAGAATATAA

Upstream 100 bases:

>100_bases
TGAATTAAACAATAATTAAGAAAATTATTTTTAATATAACAATATAATTCATTATCATTATCCTGTTTGCTAACTATTAT
ATATTTATAAGAAATAATCT

Downstream 100 bases:

>100_bases
AATTTACTATTCGAGCTGAAATTAATTAACAGCTCGAGAATATTTTTATTAATTCTGATAAAACTATAAATCAAATACAA
AAATAATTTTAAAAAATTAA

Product: RNA polymerase, b' subunit

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1410; Mature: 1410

Protein sequence:

>1410_residues
MKDILKLFKKNKKVEEFDSIKISLASPEVIRSWSFGEVKKPETINYRTLNPERDGLFCARIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTQSKVRRDRMGHIELAAPIAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVITDPGITNLEKYQVL
SEDQYIQALEENEDEFEAKMGAEAIQNLLKNMDLKKTCKILKKEVLKVNSETKRKKVTKRIKLIESLLTSKNKPEWMILT
VLPILPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELFAPEIIVRNEKRMLQEAIDALLDNGRRGRSITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLHLNQCGIPKKMALELFKPFIYGKLEQRNLATTIKSAKKM
VEKEEPIVWDILDEVIHKHPILLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAYNADFDGDQMAIHIPLTKTAQKEA
CSLMMSTKNILSPANGEPIIVPSQDVVLGIYYMTRKKINGKGENMLLSSPKEAEYMYSLGAVDLHSIVKIRILEYKKDEK
KNLTEKKKIIKTTIGRAILWIHVPMGLPFKIFNKTLRKSHISEILNTCYRLLGLKKTVRLADQMMYIGFSYAAKSGVSVG
INDIIIPKEKEKIIFQAEKEVLEIDKQFQTGLVTSSERYNKVIDIWAIANENIADAMMKNLSYEIIFQKNKKKITQKSFN
NIFIMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVITQTNCKTKKGILMNSLIEGGDIKETLKERVLGRITVENIYHLNSKNIIIPKNTLLNEKWCNILEKNFIDSI
IVRSVVHCETSFGVCAYCYGRDLARGKIVKKGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASKVASESSIQIRKNGIIHL
NQAKSVINSNGKIVIISRNVELKMLDKTGKTQESYKIPYGSILTKGEGQKVKAGEIIAKWDPHTIPVITEVNGYIKFIDM
VDGKSITKQNDELTGLSSIVVLDISERNILGKDLKPALKIIGKNEEDIFIPGTDMPAQYFLPGKSIILLEDGMKISSGDI
LARVPQESVGTKDITGGLPRVADLFEARKPKELAILAEINGIVSFGKETKGKRRLILTPIDGNNIYEEMIPKWRQLNVFE
GERVEKGDIISDGPESPHDILRLRGVQAVTNYIVNEVQEVYRLQGVKINDKHIEVIIRQMLRKATIINPGDSNFLQGEQI
EYSKITSENKKLKKNKKETATFSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKKDKLRGLKENVIVGRLIPAG
TGYKYHKKRLKNRIKNSVNKKNNMSSISVEEAAANLSELLNSTENINNRI

Sequences:

>Translated_1410_residues
MKDILKLFKKNKKVEEFDSIKISLASPEVIRSWSFGEVKKPETINYRTLNPERDGLFCARIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTQSKVRRDRMGHIELAAPIAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVITDPGITNLEKYQVL
SEDQYIQALEENEDEFEAKMGAEAIQNLLKNMDLKKTCKILKKEVLKVNSETKRKKVTKRIKLIESLLTSKNKPEWMILT
VLPILPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELFAPEIIVRNEKRMLQEAIDALLDNGRRGRSITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLHLNQCGIPKKMALELFKPFIYGKLEQRNLATTIKSAKKM
VEKEEPIVWDILDEVIHKHPILLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAYNADFDGDQMAIHIPLTKTAQKEA
CSLMMSTKNILSPANGEPIIVPSQDVVLGIYYMTRKKINGKGENMLLSSPKEAEYMYSLGAVDLHSIVKIRILEYKKDEK
KNLTEKKKIIKTTIGRAILWIHVPMGLPFKIFNKTLRKSHISEILNTCYRLLGLKKTVRLADQMMYIGFSYAAKSGVSVG
INDIIIPKEKEKIIFQAEKEVLEIDKQFQTGLVTSSERYNKVIDIWAIANENIADAMMKNLSYEIIFQKNKKKITQKSFN
NIFIMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVITQTNCKTKKGILMNSLIEGGDIKETLKERVLGRITVENIYHLNSKNIIIPKNTLLNEKWCNILEKNFIDSI
IVRSVVHCETSFGVCAYCYGRDLARGKIVKKGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASKVASESSIQIRKNGIIHL
NQAKSVINSNGKIVIISRNVELKMLDKTGKTQESYKIPYGSILTKGEGQKVKAGEIIAKWDPHTIPVITEVNGYIKFIDM
VDGKSITKQNDELTGLSSIVVLDISERNILGKDLKPALKIIGKNEEDIFIPGTDMPAQYFLPGKSIILLEDGMKISSGDI
LARVPQESVGTKDITGGLPRVADLFEARKPKELAILAEINGIVSFGKETKGKRRLILTPIDGNNIYEEMIPKWRQLNVFE
GERVEKGDIISDGPESPHDILRLRGVQAVTNYIVNEVQEVYRLQGVKINDKHIEVIIRQMLRKATIINPGDSNFLQGEQI
EYSKITSENKKLKKNKKETATFSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKKDKLRGLKENVIVGRLIPAG
TGYKYHKKRLKNRIKNSVNKKNNMSSISVEEAAANLSELLNSTENINNRI
>Mature_1410_residues
MKDILKLFKKNKKVEEFDSIKISLASPEVIRSWSFGEVKKPETINYRTLNPERDGLFCARIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTQSKVRRDRMGHIELAAPIAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVITDPGITNLEKYQVL
SEDQYIQALEENEDEFEAKMGAEAIQNLLKNMDLKKTCKILKKEVLKVNSETKRKKVTKRIKLIESLLTSKNKPEWMILT
VLPILPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELFAPEIIVRNEKRMLQEAIDALLDNGRRGRSITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLHLNQCGIPKKMALELFKPFIYGKLEQRNLATTIKSAKKM
VEKEEPIVWDILDEVIHKHPILLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAYNADFDGDQMAIHIPLTKTAQKEA
CSLMMSTKNILSPANGEPIIVPSQDVVLGIYYMTRKKINGKGENMLLSSPKEAEYMYSLGAVDLHSIVKIRILEYKKDEK
KNLTEKKKIIKTTIGRAILWIHVPMGLPFKIFNKTLRKSHISEILNTCYRLLGLKKTVRLADQMMYIGFSYAAKSGVSVG
INDIIIPKEKEKIIFQAEKEVLEIDKQFQTGLVTSSERYNKVIDIWAIANENIADAMMKNLSYEIIFQKNKKKITQKSFN
NIFIMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVITQTNCKTKKGILMNSLIEGGDIKETLKERVLGRITVENIYHLNSKNIIIPKNTLLNEKWCNILEKNFIDSI
IVRSVVHCETSFGVCAYCYGRDLARGKIVKKGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASKVASESSIQIRKNGIIHL
NQAKSVINSNGKIVIISRNVELKMLDKTGKTQESYKIPYGSILTKGEGQKVKAGEIIAKWDPHTIPVITEVNGYIKFIDM
VDGKSITKQNDELTGLSSIVVLDISERNILGKDLKPALKIIGKNEEDIFIPGTDMPAQYFLPGKSIILLEDGMKISSGDI
LARVPQESVGTKDITGGLPRVADLFEARKPKELAILAEINGIVSFGKETKGKRRLILTPIDGNNIYEEMIPKWRQLNVFE
GERVEKGDIISDGPESPHDILRLRGVQAVTNYIVNEVQEVYRLQGVKINDKHIEVIIRQMLRKATIINPGDSNFLQGEQI
EYSKITSENKKLKKNKKETATFSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKKDKLRGLKENVIVGRLIPAG
TGYKYHKKRLKNRIKNSVNKKNNMSSISVEEAAANLSELLNSTENINNRI

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=854, Percent_Identity=24.4730679156909, Blast_Score=184, Evalue=5e-46,
Organism=Homo sapiens, GI39725938, Length=310, Percent_Identity=30.9677419354839, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI103471997, Length=596, Percent_Identity=25, Blast_Score=130, Evalue=7e-30,
Organism=Escherichia coli, GI2367335, Length=1402, Percent_Identity=74.679029957204, Blast_Score=2233, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=971, Percent_Identity=23.1719876416066, Blast_Score=179, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25145495, Length=691, Percent_Identity=26.6280752532561, Blast_Score=179, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6320061, Length=882, Percent_Identity=24.6031746031746, Blast_Score=193, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6324917, Length=827, Percent_Identity=24.0628778718259, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324690, Length=229, Percent_Identity=34.061135371179, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI17530899, Length=841, Percent_Identity=23.9001189060642, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI281360912, Length=696, Percent_Identity=25.2873563218391, Blast_Score=171, Evalue=3e-42,
Organism=Drosophila melanogaster, GI17647875, Length=329, Percent_Identity=27.6595744680851, Blast_Score=105, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_BUCCC (Q058E6)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802596.1
- ProteinModelPortal:   Q058E6
- STRING:   Q058E6
- EnsemblBacteria:   EBBUCT00000001377
- GeneID:   4440658
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_018
- eggNOG:   COG0086
- GeneTree:   EBGT00050000008021
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- BioCyc:   BAPH372461:BCC_018-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 158600; Mature: 158600

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDILKLFKKNKKVEEFDSIKISLASPEVIRSWSFGEVKKPETINYRTLNPERDGLFCAR
CHHHHHHHHCCCCCCCCCCEEEEECCHHHHHCCCCCCCCCCCCCEEEECCCCCCCEEEEH
IFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTQSKVRRDRMGHIELAAPIAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRIGLLLDMPLRDIERVLYFESYVITDPGITNLEKYQVLSEDQYIQALEENEDEFEAKM
HHHHCEEECCCHHHHHHHHHHHHEEEECCCCCCHHHHHHHCCHHHHHHHHCCHHHHHHHH
GAEAIQNLLKNMDLKKTCKILKKEVLKVNSETKRKKVTKRIKLIESLLTSKNKPEWMILT
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPILPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELFAPEIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHEECCHHHHHH
EAIDALLDNGRRGRSITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPY
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCE
LHLNQCGIPKKMALELFKPFIYGKLEQRNLATTIKSAKKMVEKEEPIVWDILDEVIHKHP
EEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
ILLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAYNADFDGDQMAIHIPLTKTAQKEA
EEECCCCCHHHHCHHHCCCEEEECCEEEEECEEEEEECCCCCCCEEEEEECCCCCHHHHH
CSLMMSTKNILSPANGEPIIVPSQDVVLGIYYMTRKKINGKGENMLLSSPKEAEYMYSLG
HHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEHHHHHCCCCCCCEEECCCCHHHHHHHCC
AVDLHSIVKIRILEYKKDEKKNLTEKKKIIKTTIGRAILWIHVPMGLPFKIFNKTLRKSH
CHHHHHHHEEHEECCCCCHHHCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHH
ISEILNTCYRLLGLKKTVRLADQMMYIGFSYAAKSGVSVGINDIIIPKEKEKIIFQAEKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEECCCCHHHHHHHHHHH
VLEIDKQFQTGLVTSSERYNKVIDIWAIANENIADAMMKNLSYEIIFQKNKKKITQKSFN
HHHHHHHHHHCCCCCCHHHCCEEEEEEECCCCHHHHHHHCCCEEEEEECCHHHHHHHCCC
NIFIMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDVAQDLVITQTNCKTKKGILMNSLIEGGDIKETLKERVL
CCHHHHHHHHCCCCHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHH
GRITVENIYHLNSKNIIIPKNTLLNEKWCNILEKNFIDSIIVRSVVHCETSFGVCAYCYG
CEEEHHHEEEECCCCEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
RDLARGKIVKKGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASKVASESSIQIRKNGIIHL
CCHHCCCEEECCCEEEEEEHHCCCCCCCEEEEEEEEECCHHHHHCCCCCEEEECCCEEEE
NQAKSVINSNGKIVIISRNVELKMLDKTGKTQESYKIPYGSILTKGEGQKVKAGEIIAKW
HHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCHHEEECCCCCEEECCCEEEEC
DPHTIPVITEVNGYIKFIDMVDGKSITKQNDELTGLSSIVVLDISERNILGKDLKPALKI
CCCCEEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHH
IGKNEEDIFIPGTDMPAQYFLPGKSIILLEDGMKISSGDILARVPQESVGTKDITGGLPR
HCCCCCCEEECCCCCCCEEECCCCEEEEEECCCEECCCCEEEECCCHHCCCCCCCCCCHH
VADLFEARKPKELAILAEINGIVSFGKETKGKRRLILTPIDGNNIYEEMIPKWRQLNVFE
HHHHHHCCCCCCEEEEEEHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHCCHHHCCCCCC
GERVEKGDIISDGPESPHDILRLRGVQAVTNYIVNEVQEVYRLQGVKINDKHIEVIIRQM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRKATIINPGDSNFLQGEQIEYSKITSENKKLKKNKKETATFSRDLLGITKASLATESFI
HHHHCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVAGKKDKLRGLKENVIVGRLIPAGTGYKYHKKRLKNRIKNSVNK
HHHHHHHHHHHHHHHHHCCCHHHHCCHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHCC
KNNMSSISVEEAAANLSELLNSTENINNRI
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKDILKLFKKNKKVEEFDSIKISLASPEVIRSWSFGEVKKPETINYRTLNPERDGLFCAR
CHHHHHHHHCCCCCCCCCCEEEEECCHHHHHCCCCCCCCCCCCCEEEECCCCCCCEEEEH
IFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTQSKVRRDRMGHIELAAPIAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRIGLLLDMPLRDIERVLYFESYVITDPGITNLEKYQVLSEDQYIQALEENEDEFEAKM
HHHHCEEECCCHHHHHHHHHHHHEEEECCCCCCHHHHHHHCCHHHHHHHHCCHHHHHHHH
GAEAIQNLLKNMDLKKTCKILKKEVLKVNSETKRKKVTKRIKLIESLLTSKNKPEWMILT
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPILPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELFAPEIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHEECCHHHHHH
EAIDALLDNGRRGRSITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPY
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCE
LHLNQCGIPKKMALELFKPFIYGKLEQRNLATTIKSAKKMVEKEEPIVWDILDEVIHKHP
EEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
ILLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAYNADFDGDQMAIHIPLTKTAQKEA
EEECCCCCHHHHCHHHCCCEEEECCEEEEECEEEEEECCCCCCCEEEEEECCCCCHHHHH
CSLMMSTKNILSPANGEPIIVPSQDVVLGIYYMTRKKINGKGENMLLSSPKEAEYMYSLG
HHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEHHHHHCCCCCCCEEECCCCHHHHHHHCC
AVDLHSIVKIRILEYKKDEKKNLTEKKKIIKTTIGRAILWIHVPMGLPFKIFNKTLRKSH
CHHHHHHHEEHEECCCCCHHHCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHH
ISEILNTCYRLLGLKKTVRLADQMMYIGFSYAAKSGVSVGINDIIIPKEKEKIIFQAEKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEECCCCHHHHHHHHHHH
VLEIDKQFQTGLVTSSERYNKVIDIWAIANENIADAMMKNLSYEIIFQKNKKKITQKSFN
HHHHHHHHHHCCCCCCHHHCCEEEEEEECCCCHHHHHHHCCCEEEEEECCHHHHHHHCCC
NIFIMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDVAQDLVITQTNCKTKKGILMNSLIEGGDIKETLKERVL
CCHHHHHHHHCCCCHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHH
GRITVENIYHLNSKNIIIPKNTLLNEKWCNILEKNFIDSIIVRSVVHCETSFGVCAYCYG
CEEEHHHEEEECCCCEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
RDLARGKIVKKGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASKVASESSIQIRKNGIIHL
CCHHCCCEEECCCEEEEEEHHCCCCCCCEEEEEEEEECCHHHHHCCCCCEEEECCCEEEE
NQAKSVINSNGKIVIISRNVELKMLDKTGKTQESYKIPYGSILTKGEGQKVKAGEIIAKW
HHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCHHEEECCCCCEEECCCEEEEC
DPHTIPVITEVNGYIKFIDMVDGKSITKQNDELTGLSSIVVLDISERNILGKDLKPALKI
CCCCEEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHH
IGKNEEDIFIPGTDMPAQYFLPGKSIILLEDGMKISSGDILARVPQESVGTKDITGGLPR
HCCCCCCEEECCCCCCCEEECCCCEEEEEECCCEECCCCEEEECCCHHCCCCCCCCCCHH
VADLFEARKPKELAILAEINGIVSFGKETKGKRRLILTPIDGNNIYEEMIPKWRQLNVFE
HHHHHHCCCCCCEEEEEEHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHCCHHHCCCCCC
GERVEKGDIISDGPESPHDILRLRGVQAVTNYIVNEVQEVYRLQGVKINDKHIEVIIRQM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRKATIINPGDSNFLQGEQIEYSKITSENKKLKKNKKETATFSRDLLGITKASLATESFI
HHHHCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVAGKKDKLRGLKENVIVGRLIPAGTGYKYHKKRLKNRIKNSVNK
HHHHHHHHHHHHHHHHHCCCHHHHCCHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHCC
KNNMSSISVEEAAANLSELLNSTENINNRI
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA