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The map label for this gene is luxS

Identifier: 116494309

GI number: 116494309

Start: 760265

End: 760738

Strand: Direct

Name: luxS

Synonym: LSEI_0765

Alternate gene names: 116494309

Gene position: 760265-760738 (Clockwise)

Preceding gene: 116494308

Following gene: 116494310

Centisome position: 26.26

GC content: 48.31

Gene sequence:

>474_bases
ATGGCAAAAGTTGAAAGTTTCACCTTGGATCACACAGCTGTTAAAGCACCTTATGTTCGGTTGATTACGACAGAGCACGG
TGCAAAGGGTGATGTGATTTCAAACTATGATTTGCGGTTGGTACAACCAAACACAGCAGCCATTGATACGGCTGGCTTGC
ACACGATTGAACACTTGCTGGCATCGTTATTGCGCGATCGGATGGACGGCGTTATTGATTGTTCACCATTCGGCTGCCGC
ACCGGTTTCCACTTGATTACTTGGGGTGAGCACAGCACAACCGAAGTGGCCAAGGCTTTGAAGTCAAGCTTAGAGGCCAT
TGCCAATGACATTACTTGGGATGACGTCCCTGGTGTTGACATCAAGAGTTGTGGCAATTACAAGGATCACAGCCTGTTTT
CAGCAAAGGAGTGGGCGAAGTTAATTTTGAGCCGCGGCATTTCAAATGACCCGTACACGCGTCAGGTTGTCTGA

Upstream 100 bases:

>100_bases
TTCTGAGCGCTCCTGCTCGCGCTCAGATTTTTTTAACAGATACCACTGTTGTGTTATATGATAAATGTGTCATCAAAACT
AAAAGGGAGATTTCTACATT

Downstream 100 bases:

>100_bases
GGCTTGGTTTCAATCCCACCAGCTCAAAATTGCCGCATAAAAATGGCACTGCTACAACTCGCTAAATGAGTTTGACAGTG
CCATTTTCATGTTCGAAGGA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MAKVESFTLDHTAVKAPYVRLITTEHGAKGDVISNYDLRLVQPNTAAIDTAGLHTIEHLLASLLRDRMDGVIDCSPFGCR
TGFHLITWGEHSTTEVAKALKSSLEAIANDITWDDVPGVDIKSCGNYKDHSLFSAKEWAKLILSRGISNDPYTRQVV

Sequences:

>Translated_157_residues
MAKVESFTLDHTAVKAPYVRLITTEHGAKGDVISNYDLRLVQPNTAAIDTAGLHTIEHLLASLLRDRMDGVIDCSPFGCR
TGFHLITWGEHSTTEVAKALKSSLEAIANDITWDDVPGVDIKSCGNYKDHSLFSAKEWAKLILSRGISNDPYTRQVV
>Mature_156_residues
AKVESFTLDHTAVKAPYVRLITTEHGAKGDVISNYDLRLVQPNTAAIDTAGLHTIEHLLASLLRDRMDGVIDCSPFGCRT
GFHLITWGEHSTTEVAKALKSSLEAIANDITWDDVPGVDIKSCGNYKDHSLFSAKEWAKLILSRGISNDPYTRQVV

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=151, Percent_Identity=37.7483443708609, Blast_Score=119, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_LACC3 (Q03B21)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_806043.1
- ProteinModelPortal:   Q03B21
- SMR:   Q03B21
- STRING:   Q03B21
- GeneID:   4419370
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_0765
- eggNOG:   COG1854
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- PhylomeDB:   Q03B21
- ProtClustDB:   PRK02260
- BioCyc:   LCAS321967:LSEI_0765-MONOMER
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 17267; Mature: 17136

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVESFTLDHTAVKAPYVRLITTEHGAKGDVISNYDLRLVQPNTAAIDTAGLHTIEHLL
CCCCCCEECCCHHHCCCEEEEEEECCCCCCCEECCCCEEEECCCCCEECHHHHHHHHHHH
ASLLRDRMDGVIDCSPFGCRTGFHLITWGEHSTTEVAKALKSSLEAIANDITWDDVPGVD
HHHHHHHHCCEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
IKSCGNYKDHSLFSAKEWAKLILSRGISNDPYTRQVV
HHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AKVESFTLDHTAVKAPYVRLITTEHGAKGDVISNYDLRLVQPNTAAIDTAGLHTIEHLL
CCCCCEECCCHHHCCCEEEEEEECCCCCCCEECCCCEEEECCCCCEECHHHHHHHHHHH
ASLLRDRMDGVIDCSPFGCRTGFHLITWGEHSTTEVAKALKSSLEAIANDITWDDVPGVD
HHHHHHHHCCEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
IKSCGNYKDHSLFSAKEWAKLILSRGISNDPYTRQVV
HHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA