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The map label for this gene is manX [H]

Identifier: 116493489

GI number: 116493489

Start: 1736356

End: 1736751

Strand: Reverse

Name: manX [H]

Synonym: PEPE_1761

Alternate gene names: 116493489

Gene position: 1736751-1736356 (Counterclockwise)

Preceding gene: 116493490

Following gene: 116493488

Centisome position: 94.78

GC content: 39.65

Gene sequence:

>396_bases
ATGAGATTATTGTTAATGAGTCACGGAAATATGGCGGTTGAAACTTTAGCTAGTGCGGAAATGATTCTTGGGCATATTGA
TAACATGAAGGCTATTGGGCTTCAACCTAATCAAGGTCCAGAAGATTTACAGGCCGAAGCAGAGCAGTTTATCAATGACA
ACCCCAATAACGAAAAGACAATGGTGGCGGTTGATTTACTAGGTGGAACCCCCTCCAATGTTGTGGTTCGTTTGATGGCT
GAACATCCAGAACTTGAAGTAGTTAGTGGTTTGAATCTTCCCATGGTGATTGGTTTTGCCAATCAAGTAATGATGGGAAT
GGAAGTAAGTAAACAATCTGTAATTGATGAAGCACAAAATGGAATTATTGACGTAAATGCAAAACTAAACGGGTAA

Upstream 100 bases:

>100_bases
TATGATATGAATTGAGCTGGTAGTAATATCAGCTGTTTATTTACAGGTGTTTGTAAGCGTATACAACATAATTACAAACC
CTGGGATGGAGGAATGTTAC

Downstream 100 bases:

>100_bases
AAAATATGGCAGAAACCTATCAATATTCATTAAGATTCGCAATTGATCCTTTTAACTGGAATGAAGAACGAGCGAAGAAG
TTAATTAAATTTTGTCAGGA

Product: phosphotransferase system, mannose/fructose-specific component IIA

Products: NA

Alternate protein names: EIIAB-Man; Mannose-specific phosphotransferase enzyme IIA component; EIII-Man; PTS system mannose-specific EIIA component; Mannose-specific phosphotransferase enzyme IIB component; PTS system mannose-specific EIIB component [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MRLLLMSHGNMAVETLASAEMILGHIDNMKAIGLQPNQGPEDLQAEAEQFINDNPNNEKTMVAVDLLGGTPSNVVVRLMA
EHPELEVVSGLNLPMVIGFANQVMMGMEVSKQSVIDEAQNGIIDVNAKLNG

Sequences:

>Translated_131_residues
MRLLLMSHGNMAVETLASAEMILGHIDNMKAIGLQPNQGPEDLQAEAEQFINDNPNNEKTMVAVDLLGGTPSNVVVRLMA
EHPELEVVSGLNLPMVIGFANQVMMGMEVSKQSVIDEAQNGIIDVNAKLNG
>Mature_131_residues
MRLLLMSHGNMAVETLASAEMILGHIDNMKAIGLQPNQGPEDLQAEAEQFINDNPNNEKTMVAVDLLGGTPSNVVVRLMA
EHPELEVVSGLNLPMVIGFANQVMMGMEVSKQSVIDEAQNGIIDVNAKLNG

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2893

COG function: function code G; Phosphotransferase system, mannose/fructose-specific component IIA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-4 domain [H]

Homologues:

None

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004701
- InterPro:   IPR004720 [H]

Pfam domain/function: PF03610 EIIA-man; PF03830 PTSIIB_sorb [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 14080; Mature: 14080

Theoretical pI: Translated: 4.10; Mature: 4.10

Prosite motif: PS51096 PTS_EIIA_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
8.4 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
8.4 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLLMSHGNMAVETLASAEMILGHIDNMKAIGLQPNQGPEDLQAEAEQFINDNPNNEKT
CEEEEEECCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCEE
MVAVDLLGGTPSNVVVRLMAEHPELEVVSGLNLPMVIGFANQVMMGMEVSKQSVIDEAQN
EEEEEECCCCCHHHHEEEECCCCCEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHCC
GIIDVNAKLNG
CEEEEEEEECC
>Mature Secondary Structure
MRLLLMSHGNMAVETLASAEMILGHIDNMKAIGLQPNQGPEDLQAEAEQFINDNPNNEKT
CEEEEEECCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCEE
MVAVDLLGGTPSNVVVRLMAEHPELEVVSGLNLPMVIGFANQVMMGMEVSKQSVIDEAQN
EEEEEECCCCCHHHHEEEECCCCCEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHCC
GIIDVNAKLNG
CEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA