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The map label for this gene is dsdA

Identifier: 116493473

GI number: 116493473

Start: 1721362

End: 1722660

Strand: Reverse

Name: dsdA

Synonym: PEPE_1745

Alternate gene names: 116493473

Gene position: 1722660-1721362 (Counterclockwise)

Preceding gene: 116493474

Following gene: 116493470

Centisome position: 94.01

GC content: 38.95

Gene sequence:

>1299_bases
ATGATTGATGTTGATGCTCTAAGCAAAAAATATCCAGCGATTAAGCAGATGCAAGCTTACGAACCAATTTTTTGGAAGAA
CCTGAATTATAAAAAGGAAGCTGAATTACCGGTTGGAGTTGAACATATCTTCGATGCTGAAGCTCGTTTTCAACGGTTTG
CACCTTATTTTGAGGTAGCATTCCCAGAAACTTTACCAACACATGGAATTTTAGAATCCCCTTTGCTCAAAATGGATAAG
ATGAAGGCTGTTTTAAATGCCGAAGCTCAAAACCAAGTTAAGGGTGATTTGTATCTTAAGGCTGATAATTATCTACCAAT
TTCGGGCTCAATTAAGTCACGTGGTGGAATCTACGAAGTGTTGAAATTTGCCGAAAAAGTAGCAATGAAACACGGTGAAA
TTGTATATGGTGATAATTATGCTAAATTAAATGAACCACGCTTCAAGGATTTATTTGGACAATATGGAATTGTCGTGGGC
TCAACGGGAAATCTTGGACTATCGATTGGTATTGTAGCTTGTAAACTAGGTTTTAGAACTAGCGTACATATGTCGAGCGA
TGCCGCTCAATGGAAGAAGGATATGTTACGTGAAAAGGGCGTTAATGTTGTTGAATATAACGACAATTTCACTCATGCTA
TTACAGAAGCACGTAAATCTGCTGAAGCAGATCCTATGGCTTACTTCATCGATGATGAAGGGTCGTACGATTTATTCTTG
GGATATTCGGTTGCTGCAGTTCGTCTTCAAGCTCAATTGAAGGCTCAAAATATCAAAGTTGATGCAGAACATCCATTATT
TGTATATCTACCTGCTGGAGTAGGTGGCAGTCCCAGTGGTGTAGCCTTTGGTCTAAAGAAGATTATTGGCGAAAACGTTC
ATCCAATTTTTGCGGAACCAACTCATATTCCATCTGTTTCACTAGGAATGATGACCGGCTTAAATGATCAAATTTCAGTT
TATGATGCTGGAATTGATGGAGTAACTAAGGCTGACGGTCTTGCTGTTGGGCGTCCATCTAGAATTGCTGGTAAGATGAT
GGATACATTATTATATGGAATTCAAACTTTTGATGATCAAAAGATGATGAAGAATGTTGCAGAATTGCATGACTCAGAAA
ATGTGGATGTTGAACCATCAGCTGCTTCTGGTTTTACGATTTTAGATGACGTTCAAGCTCAATTGGAACAGGATTATCCA
ATGGAAAATGCTAGCCATATTGTTTGGGCGACGGGTGGTAGCATGGTGCCTAAGAATGATATGGACCAGTATGTGGCTGA
AGGACATCAAGTTAAATAA

Upstream 100 bases:

>100_bases
AATTTGTGAATGAATACATTAATTCTTGAAATAGGGGTTAGCAAAGCATTCTAGGCGTTGTATACTAAATGTGAATACAA
TAACGAGGAGATAAAAAATT

Downstream 100 bases:

>100_bases
TTGAATACTAGGATATAAAAAAAGGTGAACCTCTATGGGTTCACCTTTTTATTTATTTCTTTTTAGGCAATACGATTAAT
TTATATAACCAAGTTGTTAG

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MIDVDALSKKYPAIKQMQAYEPIFWKNLNYKKEAELPVGVEHIFDAEARFQRFAPYFEVAFPETLPTHGILESPLLKMDK
MKAVLNAEAQNQVKGDLYLKADNYLPISGSIKSRGGIYEVLKFAEKVAMKHGEIVYGDNYAKLNEPRFKDLFGQYGIVVG
STGNLGLSIGIVACKLGFRTSVHMSSDAAQWKKDMLREKGVNVVEYNDNFTHAITEARKSAEADPMAYFIDDEGSYDLFL
GYSVAAVRLQAQLKAQNIKVDAEHPLFVYLPAGVGGSPSGVAFGLKKIIGENVHPIFAEPTHIPSVSLGMMTGLNDQISV
YDAGIDGVTKADGLAVGRPSRIAGKMMDTLLYGIQTFDDQKMMKNVAELHDSENVDVEPSAASGFTILDDVQAQLEQDYP
MENASHIVWATGGSMVPKNDMDQYVAEGHQVK

Sequences:

>Translated_432_residues
MIDVDALSKKYPAIKQMQAYEPIFWKNLNYKKEAELPVGVEHIFDAEARFQRFAPYFEVAFPETLPTHGILESPLLKMDK
MKAVLNAEAQNQVKGDLYLKADNYLPISGSIKSRGGIYEVLKFAEKVAMKHGEIVYGDNYAKLNEPRFKDLFGQYGIVVG
STGNLGLSIGIVACKLGFRTSVHMSSDAAQWKKDMLREKGVNVVEYNDNFTHAITEARKSAEADPMAYFIDDEGSYDLFL
GYSVAAVRLQAQLKAQNIKVDAEHPLFVYLPAGVGGSPSGVAFGLKKIIGENVHPIFAEPTHIPSVSLGMMTGLNDQISV
YDAGIDGVTKADGLAVGRPSRIAGKMMDTLLYGIQTFDDQKMMKNVAELHDSENVDVEPSAASGFTILDDVQAQLEQDYP
MENASHIVWATGGSMVPKNDMDQYVAEGHQVK
>Mature_432_residues
MIDVDALSKKYPAIKQMQAYEPIFWKNLNYKKEAELPVGVEHIFDAEARFQRFAPYFEVAFPETLPTHGILESPLLKMDK
MKAVLNAEAQNQVKGDLYLKADNYLPISGSIKSRGGIYEVLKFAEKVAMKHGEIVYGDNYAKLNEPRFKDLFGQYGIVVG
STGNLGLSIGIVACKLGFRTSVHMSSDAAQWKKDMLREKGVNVVEYNDNFTHAITEARKSAEADPMAYFIDDEGSYDLFL
GYSVAAVRLQAQLKAQNIKVDAEHPLFVYLPAGVGGSPSGVAFGLKKIIGENVHPIFAEPTHIPSVSLGMMTGLNDQISV
YDAGIDGVTKADGLAVGRPSRIAGKMMDTLLYGIQTFDDQKMMKNVAELHDSENVDVEPSAASGFTILDDVQAQLEQDYP
MENASHIVWATGGSMVPKNDMDQYVAEGHQVK

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily

Homologues:

Organism=Escherichia coli, GI1788708, Length=437, Percent_Identity=51.0297482837529, Blast_Score=405, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHD_PEDPA (Q03DF6)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_805208.1
- STRING:   Q03DF6
- GeneID:   4417441
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1745
- NMPDR:   fig|278197.10.peg.1544
- eggNOG:   COG3048
- HOGENOM:   HBG288722
- OMA:   WKKDLLR
- PhylomeDB:   Q03DF6
- ProtClustDB:   PRK02991
- BioCyc:   PPEN278197:PEPE_1745-MONOMER
- HAMAP:   MF_01030
- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634
- PANTHER:   PTHR10314:SF9
- TIGRFAMs:   TIGR02035

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.3.1.18

Molecular weight: Translated: 47550; Mature: 47550

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDVDALSKKYPAIKQMQAYEPIFWKNLNYKKEAELPVGVEHIFDAEARFQRFAPYFEVA
CCCHHHHHHCCCHHHHHHHCCCHHCCCCCCCCCCCCCCCHHHHHCHHHHHHHCCCCEEEE
FPETLPTHGILESPLLKMDKMKAVLNAEAQNQVKGDLYLKADNYLPISGSIKSRGGIYEV
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCEEEEEECCEEECCCCCCCCCCHHHH
LKFAEKVAMKHGEIVYGDNYAKLNEPRFKDLFGQYGIVVGSTGNLGLSIGIVACKLGFRT
HHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHCCCCEEEECCCCCCEEEEEEEEECCCCE
SVHMSSDAAQWKKDMLREKGVNVVEYNDNFTHAITEARKSAEADPMAYFIDDEGSYDLFL
EEECCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEE
GYSVAAVRLQAQLKAQNIKVDAEHPLFVYLPAGVGGSPSGVAFGLKKIIGENVHPIFAEP
CCCEEEHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEECCC
THIPSVSLGMMTGLNDQISVYDAGIDGVTKADGLAVGRPSRIAGKMMDTLLYGIQTFDDQ
CCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHCCCHH
KMMKNVAELHDSENVDVEPSAASGFTILDDVQAQLEQDYPMENASHIVWATGGSMVPKND
HHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCH
MDQYVAEGHQVK
HHHHHHCCCCCC
>Mature Secondary Structure
MIDVDALSKKYPAIKQMQAYEPIFWKNLNYKKEAELPVGVEHIFDAEARFQRFAPYFEVA
CCCHHHHHHCCCHHHHHHHCCCHHCCCCCCCCCCCCCCCHHHHHCHHHHHHHCCCCEEEE
FPETLPTHGILESPLLKMDKMKAVLNAEAQNQVKGDLYLKADNYLPISGSIKSRGGIYEV
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCEEEEEECCEEECCCCCCCCCCHHHH
LKFAEKVAMKHGEIVYGDNYAKLNEPRFKDLFGQYGIVVGSTGNLGLSIGIVACKLGFRT
HHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHCCCCEEEECCCCCCEEEEEEEEECCCCE
SVHMSSDAAQWKKDMLREKGVNVVEYNDNFTHAITEARKSAEADPMAYFIDDEGSYDLFL
EEECCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEE
GYSVAAVRLQAQLKAQNIKVDAEHPLFVYLPAGVGGSPSGVAFGLKKIIGENVHPIFAEP
CCCEEEHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEECCC
THIPSVSLGMMTGLNDQISVYDAGIDGVTKADGLAVGRPSRIAGKMMDTLLYGIQTFDDQ
CCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHCCCHH
KMMKNVAELHDSENVDVEPSAASGFTILDDVQAQLEQDYPMENASHIVWATGGSMVPKND
HHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCH
MDQYVAEGHQVK
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA