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The map label for this gene is xerD [H]

Identifier: 116492850

GI number: 116492850

Start: 1083302

End: 1084189

Strand: Reverse

Name: xerD [H]

Synonym: PEPE_1088

Alternate gene names: 116492850

Gene position: 1084189-1083302 (Counterclockwise)

Preceding gene: 116492851

Following gene: 116492849

Centisome position: 59.17

GC content: 35.14

Gene sequence:

>888_bases
ATGAATGATTTAATCAATGACTATTTACATTCTCTTAAAGTAGAGCGAGGCTTATCTGATAATACAATTATTAGTTACCG
CCAAGAATTACGTCACTTGAATGACTATTTGACTAAAGAAAAAATTACAGATATAAAAAAAATTGATCGGTATGCAATCT
TAGATTATTTAGATGAGCTCAAGAAAACTGGTAGGGCAAGAAGTTCTTCAATTCATACCATTTCAAGTTTAAGAAAGTTT
TTTAAGTACTTATTGATTGTGGATAAGATTGATGTTGATCCCATGGTTAATATTGATCCACCTAAAAGAGCTCACCATTT
GCCTTCAGTACTAACGACAGCGGAAGTAGAAAAGCTGTTGCAGGTTCCAAATACAAATGAACCACTTGGAATGCGGGATC
GAACTATTCTAGAAGTTATGTATGCAACAGGATTACGAGTTAGTGAGTTAATTACATTGAATTTAAACGAACTCCATCTG
GAGATGGGACTAATTGAAACGATTGGGAAAGGGAATAAAAAACGAATCATTCCAATCGGTGACGTGGCGATTAAATGGCT
TAATCGATATATTAATGGACCGCGTAGAATTTTATTGGGTGATAAAAAGTACAATGAAATCTTCTTAAACCAACATGGAC
ATCCATTAACAAGACAAGGGATTTGGAAGAATCTTAAAGCTCAGGTTAAAAAAGCTGGAATTGAAAAAAATATTACTCCC
CATACCCTTCGGCATTCTTTTGCGACCCATTTGTTAGAGAATGGAGCAGATCTCAGGATTGTCCAGGAGTTATTAGGTCA
TGCTGATATTTCAACGACTCAAATTTACACGCATATTACGCAGCAAAGGTTGGTTGATGTATATGACAAATATCATCCAC
GAGCCTAA

Upstream 100 bases:

>100_bases
GTATTAGTAAAGGACGTTTCAAAATGGCATTGGGACATTTGCTTAAGGCTGGTGTAATCCAACAAACTGAAGATGGGATT
GTTTTAAAGGAGAAATAGTC

Downstream 100 bases:

>100_bases
AGATAAAGGAGCAACATGTTAGTAAAATATTCGGATTCAAAAAGACAAATTGCGATGGGATTATTGTCGACTGTTCAAGC
ATTTAATTCAATTGATGTAG

Product: tyrosine recombinase XerD subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNDLINDYLHSLKVERGLSDNTIISYRQELRHLNDYLTKEKITDIKKIDRYAILDYLDELKKTGRARSSSIHTISSLRKF
FKYLLIVDKIDVDPMVNIDPPKRAHHLPSVLTTAEVEKLLQVPNTNEPLGMRDRTILEVMYATGLRVSELITLNLNELHL
EMGLIETIGKGNKKRIIPIGDVAIKWLNRYINGPRRILLGDKKYNEIFLNQHGHPLTRQGIWKNLKAQVKKAGIEKNITP
HTLRHSFATHLLENGADLRIVQELLGHADISTTQIYTHITQQRLVDVYDKYHPRA

Sequences:

>Translated_295_residues
MNDLINDYLHSLKVERGLSDNTIISYRQELRHLNDYLTKEKITDIKKIDRYAILDYLDELKKTGRARSSSIHTISSLRKF
FKYLLIVDKIDVDPMVNIDPPKRAHHLPSVLTTAEVEKLLQVPNTNEPLGMRDRTILEVMYATGLRVSELITLNLNELHL
EMGLIETIGKGNKKRIIPIGDVAIKWLNRYINGPRRILLGDKKYNEIFLNQHGHPLTRQGIWKNLKAQVKKAGIEKNITP
HTLRHSFATHLLENGADLRIVQELLGHADISTTQIYTHITQQRLVDVYDKYHPRA
>Mature_295_residues
MNDLINDYLHSLKVERGLSDNTIISYRQELRHLNDYLTKEKITDIKKIDRYAILDYLDELKKTGRARSSSIHTISSLRKF
FKYLLIVDKIDVDPMVNIDPPKRAHHLPSVLTTAEVEKLLQVPNTNEPLGMRDRTILEVMYATGLRVSELITLNLNELHL
EMGLIETIGKGNKKRIIPIGDVAIKWLNRYINGPRRILLGDKKYNEIFLNQHGHPLTRQGIWKNLKAQVKKAGIEKNITP
HTLRHSFATHLLENGADLRIVQELLGHADISTTQIYTHITQQRLVDVYDKYHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=40.7534246575342, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI1790244, Length=298, Percent_Identity=37.9194630872483, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1790767, Length=188, Percent_Identity=28.1914893617021, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790768, Length=185, Percent_Identity=28.1081081081081, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34099; Mature: 34099

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLINDYLHSLKVERGLSDNTIISYRQELRHLNDYLTKEKITDIKKIDRYAILDYLDEL
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKTGRARSSSIHTISSLRKFFKYLLIVDKIDVDPMVNIDPPKRAHHLPSVLTTAEVEKLL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QVPNTNEPLGMRDRTILEVMYATGLRVSELITLNLNELHLEMGLIETIGKGNKKRIIPIG
HCCCCCCCCCCCHHHHHHHHHHCCCCHHHEEEECHHHHHHHHHHHHHHCCCCCEEEEEHH
DVAIKWLNRYINGPRRILLGDKKYNEIFLNQHGHPLTRQGIWKNLKAQVKKAGIEKNITP
HHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCH
HTLRHSFATHLLENGADLRIVQELLGHADISTTQIYTHITQQRLVDVYDKYHPRA
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNDLINDYLHSLKVERGLSDNTIISYRQELRHLNDYLTKEKITDIKKIDRYAILDYLDEL
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKTGRARSSSIHTISSLRKFFKYLLIVDKIDVDPMVNIDPPKRAHHLPSVLTTAEVEKLL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QVPNTNEPLGMRDRTILEVMYATGLRVSELITLNLNELHLEMGLIETIGKGNKKRIIPIG
HCCCCCCCCCCCHHHHHHHHHHCCCCHHHEEEECHHHHHHHHHHHHHHCCCCCEEEEEHH
DVAIKWLNRYINGPRRILLGDKKYNEIFLNQHGHPLTRQGIWKNLKAQVKKAGIEKNITP
HHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCH
HTLRHSFATHLLENGADLRIVQELLGHADISTTQIYTHITQQRLVDVYDKYHPRA
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]