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The map label for this gene is ctpA [H]

Identifier: 116492825

GI number: 116492825

Start: 1059135

End: 1060553

Strand: Reverse

Name: ctpA [H]

Synonym: PEPE_1062

Alternate gene names: 116492825

Gene position: 1060553-1059135 (Counterclockwise)

Preceding gene: 116492826

Following gene: 116492824

Centisome position: 57.88

GC content: 35.59

Gene sequence:

>1419_bases
ATGAAAAAAATAATAGAAAAACATCCGTATTTAACTATCGTATTTTCCATGATTTTAGGAGTTTTAATTACTATTGTCAG
TGGTTTAGTATTTTTTGTAGGGATTTTAGGTCATACCGATGGTGAGAAAAATGATTTTAATCGTGTAGCGAGTGTTTATA
ATCAAATTAATAGTGATTATTATAAAAAAGTCGACACTTCTAAATTAGCTACAGGAGCAATTGATGGAATGTTGAGCACT
TTAAATGACCCATTTTCGGACTATTTAACTGATAGTGATGCTACTAGTTTGAATGATAGTGTTTCAGGAGCCTTCGGTGG
TGTTGGTATTCAAGTTGTAAAGAAGAATCACCAAATTGAAGTTATGACTACCATTGATGGTACACCGGCCAAAAAAGCGG
GTCTGAAAGCCGGAGATGTGATTTTAGAAGTAGATGGTAAGAAATTAACTAATCAATCCCTTTCTAAAGCCACCACCTTA
ATGCGAGGAAAAGTTGGGACTAAAGTAAAGGTTAAATTGCAGCGAGGAAATGATACCTTTGATAAGGTGCTAACTCGTTC
TAAAATTCCAGTTGAGACCGTCACGGCTAAGATGTTGAAGAATAAAGTAGGTTATATAACTATCTCAACAGTGGCTGAAA
AAACTTCTAGTGAACTTAAACGGGCGCTTAAACGTTTAGATAAACAGGGAGCTAAATCTTATATTATTGATGTCCGAAAT
AATCCGGGTGGTCTGATGCAGGAAGCTTTAAAGATGTCTTCGATGTTTTTAAAGAATGGCAAAACTATTATGCAAGTTAA
AGCTCGGACTGGTAAAGCAGAAGTATACAAGGCGTCTAAAAAGTATGATGGTGGCTATAAAGTTACTAAACCTACTACAG
TTGTTATTAATGGCGAAAGCGCTAGTGCAGCTGAAATTTTTGCTGCAGCTTTACACCAATCGGCTAATGTTCCACTTGTA
GGTTCCAAAAGTTATGGAAAAGGCACCGTTCAAAATATTACCCAATATACAGATAGTGATGAATTAAAGCTAACGATTGC
AAAATGGTTAACGCCAAACGGTACTTGGATTCATGGAAAAGGGTTAAAACCAGACTATCAGGCTGATTATCCTGCCATGG
CATACATTACAGAATTTGATCAGAAAAAAACGTACTCCGTGGGAGAGAGCAATTCAGATATTAAAAATATTCAAATTGCC
TTAAAGGGATTAGGTTACTATGATGATAAAATTTCTAAAGAGTATACTGAGAAAGTCAAGCAGGCAGTGGAAGCTTATCA
AGAAAAGAATCAGCTAGCTGTTACTGGAAAAGTTGATGCGAAGACAATGCGTTCAATCGAACAGAATGTCATTAAAACTT
TAGCTAAAAATGATCCTGCTCTAGAAAAAGCGCAAAAAGTTATGAATGACGAAAAATAA

Upstream 100 bases:

>100_bases
ATGAGATCAGTAAATATTTAGAGCTCAATGCGGGCTATCTACAAAGTATGTCAATTTTTGATTCAGCGTGGCAAAGATAT
TTAGAAAGTGAACAGTTTTA

Downstream 100 bases:

>100_bases
ATTGATTTAAGGCCCTACAGTTGTAGGGCCTTTTTGATTGGAATTTTTGAACTAATTTAAATATGGTAACGTTTTATTCA
AACTTTCTAACAAAAAGTCA

Product: periplasmic protease

Products: NA

Alternate protein names: C-terminal processing protease [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MKKIIEKHPYLTIVFSMILGVLITIVSGLVFFVGILGHTDGEKNDFNRVASVYNQINSDYYKKVDTSKLATGAIDGMLST
LNDPFSDYLTDSDATSLNDSVSGAFGGVGIQVVKKNHQIEVMTTIDGTPAKKAGLKAGDVILEVDGKKLTNQSLSKATTL
MRGKVGTKVKVKLQRGNDTFDKVLTRSKIPVETVTAKMLKNKVGYITISTVAEKTSSELKRALKRLDKQGAKSYIIDVRN
NPGGLMQEALKMSSMFLKNGKTIMQVKARTGKAEVYKASKKYDGGYKVTKPTTVVINGESASAAEIFAAALHQSANVPLV
GSKSYGKGTVQNITQYTDSDELKLTIAKWLTPNGTWIHGKGLKPDYQADYPAMAYITEFDQKKTYSVGESNSDIKNIQIA
LKGLGYYDDKISKEYTEKVKQAVEAYQEKNQLAVTGKVDAKTMRSIEQNVIKTLAKNDPALEKAQKVMNDEK

Sequences:

>Translated_472_residues
MKKIIEKHPYLTIVFSMILGVLITIVSGLVFFVGILGHTDGEKNDFNRVASVYNQINSDYYKKVDTSKLATGAIDGMLST
LNDPFSDYLTDSDATSLNDSVSGAFGGVGIQVVKKNHQIEVMTTIDGTPAKKAGLKAGDVILEVDGKKLTNQSLSKATTL
MRGKVGTKVKVKLQRGNDTFDKVLTRSKIPVETVTAKMLKNKVGYITISTVAEKTSSELKRALKRLDKQGAKSYIIDVRN
NPGGLMQEALKMSSMFLKNGKTIMQVKARTGKAEVYKASKKYDGGYKVTKPTTVVINGESASAAEIFAAALHQSANVPLV
GSKSYGKGTVQNITQYTDSDELKLTIAKWLTPNGTWIHGKGLKPDYQADYPAMAYITEFDQKKTYSVGESNSDIKNIQIA
LKGLGYYDDKISKEYTEKVKQAVEAYQEKNQLAVTGKVDAKTMRSIEQNVIKTLAKNDPALEKAQKVMNDEK
>Mature_472_residues
MKKIIEKHPYLTIVFSMILGVLITIVSGLVFFVGILGHTDGEKNDFNRVASVYNQINSDYYKKVDTSKLATGAIDGMLST
LNDPFSDYLTDSDATSLNDSVSGAFGGVGIQVVKKNHQIEVMTTIDGTPAKKAGLKAGDVILEVDGKKLTNQSLSKATTL
MRGKVGTKVKVKLQRGNDTFDKVLTRSKIPVETVTAKMLKNKVGYITISTVAEKTSSELKRALKRLDKQGAKSYIIDVRN
NPGGLMQEALKMSSMFLKNGKTIMQVKARTGKAEVYKASKKYDGGYKVTKPTTVVINGESASAAEIFAAALHQSANVPLV
GSKSYGKGTVQNITQYTDSDELKLTIAKWLTPNGTWIHGKGLKPDYQADYPAMAYITEFDQKKTYSVGESNSDIKNIQIA
LKGLGYYDDKISKEYTEKVKQAVEAYQEKNQLAVTGKVDAKTMRSIEQNVIKTLAKNDPALEKAQKVMNDEK

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Associated With The Periplasmic Protein Side Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=309, Percent_Identity=29.7734627831715, Blast_Score=115, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 51652; Mature: 51652

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIEKHPYLTIVFSMILGVLITIVSGLVFFVGILGHTDGEKNDFNRVASVYNQINSDY
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCHHH
YKKVDTSKLATGAIDGMLSTLNDPFSDYLTDSDATSLNDSVSGAFGGVGIQVVKKNHQIE
HHHCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEE
VMTTIDGTPAKKAGLKAGDVILEVDGKKLTNQSLSKATTLMRGKVGTKVKVKLQRGNDTF
EEEECCCCCCHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHH
DKVLTRSKIPVETVTAKMLKNKVGYITISTVAEKTSSELKRALKRLDKQGAKSYIIDVRN
HHHHHCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
NPGGLMQEALKMSSMFLKNGKTIMQVKARTGKAEVYKASKKYDGGYKVTKPTTVVINGES
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCCCCCEEECCCEEEEEECCC
ASAAEIFAAALHQSANVPLVGSKSYGKGTVQNITQYTDSDELKLTIAKWLTPNGTWIHGK
CCHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHCCCCCCEEEEEEEEECCCCCEEECC
GLKPDYQADYPAMAYITEFDQKKTYSVGESNSDIKNIQIALKGLGYYDDKISKEYTEKVK
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHEEEEEECCCCCHHHHHHHHHHHHH
QAVEAYQEKNQLAVTGKVDAKTMRSIEQNVIKTLAKNDPALEKAQKVMNDEK
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKIIEKHPYLTIVFSMILGVLITIVSGLVFFVGILGHTDGEKNDFNRVASVYNQINSDY
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCHHH
YKKVDTSKLATGAIDGMLSTLNDPFSDYLTDSDATSLNDSVSGAFGGVGIQVVKKNHQIE
HHHCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEE
VMTTIDGTPAKKAGLKAGDVILEVDGKKLTNQSLSKATTLMRGKVGTKVKVKLQRGNDTF
EEEECCCCCCHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHH
DKVLTRSKIPVETVTAKMLKNKVGYITISTVAEKTSSELKRALKRLDKQGAKSYIIDVRN
HHHHHCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
NPGGLMQEALKMSSMFLKNGKTIMQVKARTGKAEVYKASKKYDGGYKVTKPTTVVINGES
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCCCCCEEECCCEEEEEECCC
ASAAEIFAAALHQSANVPLVGSKSYGKGTVQNITQYTDSDELKLTIAKWLTPNGTWIHGK
CCHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHCCCCCCEEEEEEEEECCCCCEEECC
GLKPDYQADYPAMAYITEFDQKKTYSVGESNSDIKNIQIALKGLGYYDDKISKEYTEKVK
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHEEEEEECCCCCHHHHHHHHHHHHH
QAVEAYQEKNQLAVTGKVDAKTMRSIEQNVIKTLAKNDPALEKAQKVMNDEK
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8996100; 9734814; 9384377 [H]