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The map label for this gene is yfbQ [C]

Identifier: 116492051

GI number: 116492051

Start: 294485

End: 295660

Strand: Direct

Name: yfbQ [C]

Synonym: PEPE_0247

Alternate gene names: 116492051

Gene position: 294485-295660 (Clockwise)

Preceding gene: 116492050

Following gene: 116492053

Centisome position: 16.07

GC content: 42.26

Gene sequence:

>1176_bases
ATGGAATTTTCGAAGCGGGCTAATCAAGTTAGTCCATCAGCAACATTAGCAGTTTCAACTGAGGCAAAAAAAATGCAGGC
GGCCGGCATCGACGTTGTTAATTTGAGTACGGGAGAACCGGATTTTGCTACTCCTAAGGCGATTATTAAAGCGGCGATGG
AAAGCATGGAATCTGGTAAAGCAAGTTATTACACACCAGTCGGAGGGCTCCCAGAACTTCGCCAAGCAGTTGCTACGCAC
ATTAAAACCGATACAGGTTATGATGCCAAAATGGAACAAGTGGCAGTAACGGTAGGGGCTAAAATGGGGCTGTTCGAAAC
TTTCCAAGCTTTATTGAATGAAGGCGATGAAGTCATGATCGTTGCCCCATTCTGGGTTAGTTATGAGGAACAGGTGAAAT
TAGCCGGGGGTTCGGTGATTGCCATCCATCCTCAAGCTAGTGACTTGAAAACTACTCCTTCAGAATTAAGTCGTTTTAAA
ACAGCCAGCACAAAATTGTTAATTTTAAATACGCCTCAAAATCCCTCGGGATTGGTATATTCAGAAGAAGAAACACGGGC
GATTGCACAATGGGCGGTCGATAACAACGTAATATTAGTTGCAGATGAGATTTACGGTAAATTAGTTTACAATGGGGCAA
AATTCAGTTCAGTTATGAGTATGGGGAATGAAATTGTTAATAATACCATTTTAATCGATGGGGTTTCAAAAGCGTATGCA
ATGACTGGATGGCGAATTGGATATGTTGTAGCTGCTCCGCAAATTATTCGAAAAATATTGGCTTTACAAGGTCATATGAC
ATCAAATCCGACAGCGGTAGCGCAGTATGCCGCTCTGGAAGCTTTGCGTGGAGACCAATATCCAGTGGAAGAAATGCGAT
TGGCATTTGAAAAAAGGTTGAACCAAACTTTTGATTTAATGCAAGTAATCCCTGGTTTTAGTTTTGATTATAAGCCGGAA
GGGGCTTTCTATTTATTTCCGGATGTTACTGAAGCTATGAAAATTAAAGGATATGCCACATCTACGGACTTGGCGATGGC
TTTACTAAAGGAAGCGCATGTAGCCGTTGTCGCCGGTGAAGCGTTTGGAATGCCGGGACATATTCGACTTTCGTATGCGA
CGAGCCAAACATTATTGAGTGAAGCAGTTCGTCGGATCCAAAATTTTATGAATTAA

Upstream 100 bases:

>100_bases
AGAGCACCTTTCGACGCGACCATTAAGAAGATTTATGCTACCCCTGAAATGCAAATCGAGACGGGAGATTTATTGATTGA
ACTAGAAAAGGAGTAATCTG

Downstream 100 bases:

>100_bases
TTAGAGCTATATAAAAAGCAGATACCTAACCGGTACCTGCTTTTTATATGGTTTTATAACATAGGTAAGATAACGGTCAT
CCATAGCCACGAAATGGGCA

Product: aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MEFSKRANQVSPSATLAVSTEAKKMQAAGIDVVNLSTGEPDFATPKAIIKAAMESMESGKASYYTPVGGLPELRQAVATH
IKTDTGYDAKMEQVAVTVGAKMGLFETFQALLNEGDEVMIVAPFWVSYEEQVKLAGGSVIAIHPQASDLKTTPSELSRFK
TASTKLLILNTPQNPSGLVYSEEETRAIAQWAVDNNVILVADEIYGKLVYNGAKFSSVMSMGNEIVNNTILIDGVSKAYA
MTGWRIGYVVAAPQIIRKILALQGHMTSNPTAVAQYAALEALRGDQYPVEEMRLAFEKRLNQTFDLMQVIPGFSFDYKPE
GAFYLFPDVTEAMKIKGYATSTDLAMALLKEAHVAVVAGEAFGMPGHIRLSYATSQTLLSEAVRRIQNFMN

Sequences:

>Translated_391_residues
MEFSKRANQVSPSATLAVSTEAKKMQAAGIDVVNLSTGEPDFATPKAIIKAAMESMESGKASYYTPVGGLPELRQAVATH
IKTDTGYDAKMEQVAVTVGAKMGLFETFQALLNEGDEVMIVAPFWVSYEEQVKLAGGSVIAIHPQASDLKTTPSELSRFK
TASTKLLILNTPQNPSGLVYSEEETRAIAQWAVDNNVILVADEIYGKLVYNGAKFSSVMSMGNEIVNNTILIDGVSKAYA
MTGWRIGYVVAAPQIIRKILALQGHMTSNPTAVAQYAALEALRGDQYPVEEMRLAFEKRLNQTFDLMQVIPGFSFDYKPE
GAFYLFPDVTEAMKIKGYATSTDLAMALLKEAHVAVVAGEAFGMPGHIRLSYATSQTLLSEAVRRIQNFMN
>Mature_391_residues
MEFSKRANQVSPSATLAVSTEAKKMQAAGIDVVNLSTGEPDFATPKAIIKAAMESMESGKASYYTPVGGLPELRQAVATH
IKTDTGYDAKMEQVAVTVGAKMGLFETFQALLNEGDEVMIVAPFWVSYEEQVKLAGGSVIAIHPQASDLKTTPSELSRFK
TASTKLLILNTPQNPSGLVYSEEETRAIAQWAVDNNVILVADEIYGKLVYNGAKFSSVMSMGNEIVNNTILIDGVSKAYA
MTGWRIGYVVAAPQIIRKILALQGHMTSNPTAVAQYAALEALRGDQYPVEEMRLAFEKRLNQTFDLMQVIPGFSFDYKPE
GAFYLFPDVTEAMKIKGYATSTDLAMALLKEAHVAVVAGEAFGMPGHIRLSYATSQTLLSEAVRRIQNFMN

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=274, Percent_Identity=32.1167883211679, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI169881279, Length=274, Percent_Identity=32.1167883211679, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI56713254, Length=335, Percent_Identity=28.3582089552239, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI56713256, Length=335, Percent_Identity=28.3582089552239, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=24.1379310344828, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI169881281, Length=180, Percent_Identity=28.8888888888889, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1788627, Length=387, Percent_Identity=29.4573643410853, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786816, Length=371, Percent_Identity=26.4150943396226, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788722, Length=384, Percent_Identity=26.5625, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=374, Percent_Identity=26.4705882352941, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=302, Percent_Identity=29.8013245033113, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71994472, Length=302, Percent_Identity=29.8013245033113, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=268, Percent_Identity=29.4776119402985, Blast_Score=107, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6322401, Length=234, Percent_Identity=31.1965811965812, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320317, Length=401, Percent_Identity=24.1895261845387, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573069, Length=316, Percent_Identity=28.4810126582279, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24646114, Length=316, Percent_Identity=28.4810126582279, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28573067, Length=316, Percent_Identity=28.4810126582279, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28573065, Length=316, Percent_Identity=28.4810126582279, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI18859735, Length=393, Percent_Identity=25.4452926208651, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42509; Mature: 42509

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFSKRANQVSPSATLAVSTEAKKMQAAGIDVVNLSTGEPDFATPKAIIKAAMESMESGK
CCCCHHCCCCCCCEEEEEECHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
ASYYTPVGGLPELRQAVATHIKTDTGYDAKMEQVAVTVGAKMGLFETFQALLNEGDEVMI
CEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHEEEECCCCCCHHHHHHHHHCCCCEEEE
VAPFWVSYEEQVKLAGGSVIAIHPQASDLKTTPSELSRFKTASTKLLILNTPQNPSGLVY
EECEECCHHHHEEECCCCEEEECCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCEE
SEEETRAIAQWAVDNNVILVADEIYGKLVYNGAKFSSVMSMGNEIVNNTILIDGVSKAYA
CCHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCHHHHH
MTGWRIGYVVAAPQIIRKILALQGHMTSNPTAVAQYAALEALRGDQYPVEEMRLAFEKRL
HCCCEEEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
NQTFDLMQVIPGFSFDYKPEGAFYLFPDVTEAMKIKGYATSTDLAMALLKEAHVAVVAGE
HHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHEECCCCCHHHHHHHHHHHCCEEEEECC
AFGMPGHIRLSYATSQTLLSEAVRRIQNFMN
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEFSKRANQVSPSATLAVSTEAKKMQAAGIDVVNLSTGEPDFATPKAIIKAAMESMESGK
CCCCHHCCCCCCCEEEEEECHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
ASYYTPVGGLPELRQAVATHIKTDTGYDAKMEQVAVTVGAKMGLFETFQALLNEGDEVMI
CEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHEEEECCCCCCHHHHHHHHHCCCCEEEE
VAPFWVSYEEQVKLAGGSVIAIHPQASDLKTTPSELSRFKTASTKLLILNTPQNPSGLVY
EECEECCHHHHEEECCCCEEEECCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCEE
SEEETRAIAQWAVDNNVILVADEIYGKLVYNGAKFSSVMSMGNEIVNNTILIDGVSKAYA
CCHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCHHHHH
MTGWRIGYVVAAPQIIRKILALQGHMTSNPTAVAQYAALEALRGDQYPVEEMRLAFEKRL
HCCCEEEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
NQTFDLMQVIPGFSFDYKPEGAFYLFPDVTEAMKIKGYATSTDLAMALLKEAHVAVVAGE
HHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHEECCCCCHHHHHHHHHHHCCEEEEECC
AFGMPGHIRLSYATSQTLLSEAVRRIQNFMN
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1990006; 2155199 [H]