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The map label for this gene is csdB [H]

Identifier: 116332565

GI number: 116332565

Start: 150876

End: 152033

Strand: Direct

Name: csdB [H]

Synonym: LBJ_4131

Alternate gene names: 116332565

Gene position: 150876-152033 (Clockwise)

Preceding gene: 116332564

Following gene: 116332566

Centisome position: 50.33

GC content: 40.5

Gene sequence:

>1158_bases
ATGCAATCCACCACGATCATCGATTGGAAAGAAATCCAAGATCTCTATCCCGTAAATCAGGAAATGATCTGGCTGAACAA
TTGTGGAACAACTCCTTGTAATCTAAATACAATCCAGGCGGTCGGGGAATATTTGGAAGGTTATTCTAGAAAAGGAAGCC
TAACGGAGGTACGTAAATATGCTTCCGTAAAACAATCGATTCGAAAGATTGTCGCAGGGCTCATCAATTGTGACGTGGAA
GAACTTTGTATCATCCACAACACGAATGAAGGGATGAATTTTCTTTCTCTCGGTTTTCATTTGAAAAACGGAGATGAAAT
TCTGCTCTTAGAGAACGAATATCCGAGTAATATTTATCCTTGGGAACATTGGAAAGAAAAAGGAATGAAAATAGGGTTCA
TTCCGATGGCCTTTACCCCGGATCAATTTTTAGAAAATCTGAAATCTTCCATTAGTTCTAAAACCAGAATCGTGGCTCTT
TCCGCCGTTCATTGGTGTACAGGAATGCCGTTTCCCTTGGAAGAGATCGGAACTTTTTTAGATTCTAGAGGGATTGAGTT
CGTTTTGGATGGCGCTCAAGGAATAGGTTTGGTTCCAGTTGATGTTAGAAAGATGAAATTAAAATACATCGCTTTCCCCG
CTTGGAAATGGCTTTTAGGTCCTCTTGGTTTGGGAATGTTATACATTCAACAAGATAAAATCGATACACTTTCATTTCCG
TTTAAAGGAACAGGCTCCGTAATCAACGACGAGGTTTACTTACCTTATCGCGCCGAACTAAAATCCGGAGCGGACCGTTA
TGAAATTTCGACCGGAAATTTTATCGACTGGGTATATTTTCAATCCACGCTCGAAATGCTTCAGAAAATAGGATTTCATT
CCGTCATGGAAAGAATTTATGAACTTGCGGATTATCTTTCCGAAGGAATGAAAAACGTCGGATTTCAAATAGAACTCGAT
CATTTCCCCGACAATCGAACTGGAATCGTGGTGGGATATAAAGAAGGAATTTCTATGGACGAACTCGTTTCTTACCTGAA
AAGAAACGGAGTCATGTGCGCCCTGCGCCTCGGGAAAGTGAGATTTTCTCCGCATATCTATAACCGCAAAGATCAACTGG
ATCGAGTTGTGACATTACTCAGTTCTTTTCCACGTTAA

Upstream 100 bases:

>100_bases
AACCGAGAAAGGCAGTGAAGAAAAGCGCAGCCAAAAAGGTTTCTCCCAAAAAATCGACTCCTAAAAAAAAGTCGGCGGCA
AAGGCTAAGAAAAAAAGGTA

Downstream 100 bases:

>100_bases
ACAAAACTAAGAGCCGATCTCAAAGCCTTAGGATGTAGGAGCTATTACAATCTTAAAAGACAGAAAAAAACCGTCAATAC
GACGGTTTCTGTGGGAACTC

Product: selenocysteine lyase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MQSTTIIDWKEIQDLYPVNQEMIWLNNCGTTPCNLNTIQAVGEYLEGYSRKGSLTEVRKYASVKQSIRKIVAGLINCDVE
ELCIIHNTNEGMNFLSLGFHLKNGDEILLLENEYPSNIYPWEHWKEKGMKIGFIPMAFTPDQFLENLKSSISSKTRIVAL
SAVHWCTGMPFPLEEIGTFLDSRGIEFVLDGAQGIGLVPVDVRKMKLKYIAFPAWKWLLGPLGLGMLYIQQDKIDTLSFP
FKGTGSVINDEVYLPYRAELKSGADRYEISTGNFIDWVYFQSTLEMLQKIGFHSVMERIYELADYLSEGMKNVGFQIELD
HFPDNRTGIVVGYKEGISMDELVSYLKRNGVMCALRLGKVRFSPHIYNRKDQLDRVVTLLSSFPR

Sequences:

>Translated_385_residues
MQSTTIIDWKEIQDLYPVNQEMIWLNNCGTTPCNLNTIQAVGEYLEGYSRKGSLTEVRKYASVKQSIRKIVAGLINCDVE
ELCIIHNTNEGMNFLSLGFHLKNGDEILLLENEYPSNIYPWEHWKEKGMKIGFIPMAFTPDQFLENLKSSISSKTRIVAL
SAVHWCTGMPFPLEEIGTFLDSRGIEFVLDGAQGIGLVPVDVRKMKLKYIAFPAWKWLLGPLGLGMLYIQQDKIDTLSFP
FKGTGSVINDEVYLPYRAELKSGADRYEISTGNFIDWVYFQSTLEMLQKIGFHSVMERIYELADYLSEGMKNVGFQIELD
HFPDNRTGIVVGYKEGISMDELVSYLKRNGVMCALRLGKVRFSPHIYNRKDQLDRVVTLLSSFPR
>Mature_385_residues
MQSTTIIDWKEIQDLYPVNQEMIWLNNCGTTPCNLNTIQAVGEYLEGYSRKGSLTEVRKYASVKQSIRKIVAGLINCDVE
ELCIIHNTNEGMNFLSLGFHLKNGDEILLLENEYPSNIYPWEHWKEKGMKIGFIPMAFTPDQFLENLKSSISSKTRIVAL
SAVHWCTGMPFPLEEIGTFLDSRGIEFVLDGAQGIGLVPVDVRKMKLKYIAFPAWKWLLGPLGLGMLYIQQDKIDTLSFP
FKGTGSVINDEVYLPYRAELKSGADRYEISTGNFIDWVYFQSTLEMLQKIGFHSVMERIYELADYLSEGMKNVGFQIELD
HFPDNRTGIVVGYKEGISMDELVSYLKRNGVMCALRLGKVRFSPHIYNRKDQLDRVVTLLSSFPR

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=236, Percent_Identity=25, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1787970, Length=386, Percent_Identity=26.6839378238342, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789175, Length=385, Percent_Identity=23.8961038961039, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI48994898, Length=167, Percent_Identity=23.3532934131737, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25143064, Length=225, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319831, Length=218, Percent_Identity=25.2293577981651, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129463, Length=240, Percent_Identity=25.4166666666667, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 43966; Mature: 43966

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSTTIIDWKEIQDLYPVNQEMIWLNNCGTTPCNLNTIQAVGEYLEGYSRKGSLTEVRKY
CCCCEECCHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
ASVKQSIRKIVAGLINCDVEELCIIHNTNEGMNFLSLGFHLKNGDEILLLENEYPSNIYP
HHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCC
WEHWKEKGMKIGFIPMAFTPDQFLENLKSSISSKTRIVALSAVHWCTGMPFPLEEIGTFL
CHHHHHCCCEEEEEEEECCHHHHHHHHHHHHCCCEEEEEEEHHHHHCCCCCCHHHHHHHH
DSRGIEFVLDGAQGIGLVPVDVRKMKLKYIAFPAWKWLLGPLGLGMLYIQQDKIDTLSFP
HCCCCEEEEECCCCCCEEEECHHHHEEEEEECHHHHHHHHHHCCCEEEEECCCCCEEECC
FKGTGSVINDEVYLPYRAELKSGADRYEISTGNFIDWVYFQSTLEMLQKIGFHSVMERIY
CCCCCCEECCCEECCCHHHHCCCCCEEEECCCCEEHHHHHHHHHHHHHHCCHHHHHHHHH
ELADYLSEGMKNVGFQIELDHFPDNRTGIVVGYKEGISMDELVSYLKRNGVMCALRLGKV
HHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCE
RFSPHIYNRKDQLDRVVTLLSSFPR
EECCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQSTTIIDWKEIQDLYPVNQEMIWLNNCGTTPCNLNTIQAVGEYLEGYSRKGSLTEVRKY
CCCCEECCHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
ASVKQSIRKIVAGLINCDVEELCIIHNTNEGMNFLSLGFHLKNGDEILLLENEYPSNIYP
HHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCC
WEHWKEKGMKIGFIPMAFTPDQFLENLKSSISSKTRIVALSAVHWCTGMPFPLEEIGTFL
CHHHHHCCCEEEEEEEECCHHHHHHHHHHHHCCCEEEEEEEHHHHHCCCCCCHHHHHHHH
DSRGIEFVLDGAQGIGLVPVDVRKMKLKYIAFPAWKWLLGPLGLGMLYIQQDKIDTLSFP
HCCCCEEEEECCCCCCEEEECHHHHEEEEEECHHHHHHHHHHCCCEEEEECCCCCEEECC
FKGTGSVINDEVYLPYRAELKSGADRYEISTGNFIDWVYFQSTLEMLQKIGFHSVMERIY
CCCCCCEECCCEECCCHHHHCCCCCEEEECCCCEEHHHHHHHHHHHHHHCCHHHHHHHHH
ELADYLSEGMKNVGFQIELDHFPDNRTGIVVGYKEGISMDELVSYLKRNGVMCALRLGKV
HHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCE
RFSPHIYNRKDQLDRVVTLLSSFPR
EECCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]