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The map label for this gene is cheB [H]

Identifier: 116328731

GI number: 116328731

Start: 2463302

End: 2464369

Strand: Reverse

Name: cheB [H]

Synonym: LBL_2105

Alternate gene names: 116328731

Gene position: 2464369-2463302 (Counterclockwise)

Preceding gene: 116328732

Following gene: 116328730

Centisome position: 68.18

GC content: 45.32

Gene sequence:

>1068_bases
ATGGTTCCGAGTCCGGTTCGTGTGGTTATTATCGATGATTCTCTACTAGTCAGAAATATCATCTCCGATCAGATTCAAAA
AGATTCGAACATTCACGTTATTGCAACCGGCAAGACCGGAGTGGATTGTATCGATCTTGCGCAGAAAATGAATCCGGATG
TGATCATTCTCGATGTGGAAATGCCTGTCATGGACGGTCTCACGGCGCTTCATGAACTTCAAAAAAAGAAACTTGGAATT
CCGGTCATCATGCTTTCCGTTTTGACTCAAAACGGCGCCGAAGCGACTTTCAAAGCTTTGGAATACGGCGCCATTGACTT
TGTGCCCAAACCTTCCAGCGTCTTTCAATTCGATCCGGAGGAAATCGGAAAGATCTTAAAATCTAAAATTCTTGCTTACT
TCGAAAGCCGGGTTCGAAGGGAAGTTTTAAAGAAAGTCTCCGTACTTGCAAAGGTTCCGGTAGGAGAACCTCACGTAAAA
AAATCTCCGGTTCAAGCGATTTGTATCGGTACTTCCACCGGCGGTCCTCGGGCGCTTCAGGAGGTATTTTCCAGAATTCC
CGAAGATATTTCCCTGCCTATCTTTGTCGTACAACATATGCCGGCAGGTTTTACTAAGGCCTTTGCAATGAGACTTAACG
ATCACTCGAAAATCAAAGTAAAGGAAGCCGAGGATGGAGAATCCATCGAACCAAATACGGGTTATGTGGCTCCGGGTGAT
GCGCATTTGTCCATTCACTCTAAAGGTGGAAGGAAATGGATTGCCCTAAGCAGGGAAGGACTTGTAAATGGACACAGACC
TTCCATCGAAGTTCTCCTAAACAGTGCAATTGAGGAATATAAGAGTGGAATGATCGGCGTAATTATGACCGGCATGGGCA
AGGACGGTTCAGCGGCCATGGTAAAAGTCAGGGAAGCCGGAGGTTCTACGATCGCACAGGACGAACAAACTTCCGTAATT
TATGGAATGAACCGTCAGGCCGTTGAAATGGGAGGCGTCGAATATATCGAGCCTGTTACTGAAATCATCAATAGGATCCA
AATCATTTTGAAAGAGAGAGGAATTTAA

Upstream 100 bases:

>100_bases
TGACGGAATTCAATCACGAGGGTAATGATCTTTTGGGTGTATTGTTGTTCCTTCCGGATTTTGACGAATTACTTCAACTG
ATTCCGAGGTTTTAATTCCG

Downstream 100 bases:

>100_bases
TATGGCCAGAATTCTCGTTGTGGATGATGCCAAATTTATGAGAACCATGGTAAAAGACGCCCTTACCCAAACCGGTCATG
AGATCGTAGGGGAAGCAGAA

Product: chemotaxis response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MVPSPVRVVIIDDSLLVRNIISDQIQKDSNIHVIATGKTGVDCIDLAQKMNPDVIILDVEMPVMDGLTALHELQKKKLGI
PVIMLSVLTQNGAEATFKALEYGAIDFVPKPSSVFQFDPEEIGKILKSKILAYFESRVRREVLKKVSVLAKVPVGEPHVK
KSPVQAICIGTSTGGPRALQEVFSRIPEDISLPIFVVQHMPAGFTKAFAMRLNDHSKIKVKEAEDGESIEPNTGYVAPGD
AHLSIHSKGGRKWIALSREGLVNGHRPSIEVLLNSAIEEYKSGMIGVIMTGMGKDGSAAMVKVREAGGSTIAQDEQTSVI
YGMNRQAVEMGGVEYIEPVTEIINRIQIILKERGI

Sequences:

>Translated_355_residues
MVPSPVRVVIIDDSLLVRNIISDQIQKDSNIHVIATGKTGVDCIDLAQKMNPDVIILDVEMPVMDGLTALHELQKKKLGI
PVIMLSVLTQNGAEATFKALEYGAIDFVPKPSSVFQFDPEEIGKILKSKILAYFESRVRREVLKKVSVLAKVPVGEPHVK
KSPVQAICIGTSTGGPRALQEVFSRIPEDISLPIFVVQHMPAGFTKAFAMRLNDHSKIKVKEAEDGESIEPNTGYVAPGD
AHLSIHSKGGRKWIALSREGLVNGHRPSIEVLLNSAIEEYKSGMIGVIMTGMGKDGSAAMVKVREAGGSTIAQDEQTSVI
YGMNRQAVEMGGVEYIEPVTEIINRIQIILKERGI
>Mature_355_residues
MVPSPVRVVIIDDSLLVRNIISDQIQKDSNIHVIATGKTGVDCIDLAQKMNPDVIILDVEMPVMDGLTALHELQKKKLGI
PVIMLSVLTQNGAEATFKALEYGAIDFVPKPSSVFQFDPEEIGKILKSKILAYFESRVRREVLKKVSVLAKVPVGEPHVK
KSPVQAICIGTSTGGPRALQEVFSRIPEDISLPIFVVQHMPAGFTKAFAMRLNDHSKIKVKEAEDGESIEPNTGYVAPGD
AHLSIHSKGGRKWIALSREGLVNGHRPSIEVLLNSAIEEYKSGMIGVIMTGMGKDGSAAMVKVREAGGSTIAQDEQTSVI
YGMNRQAVEMGGVEYIEPVTEIINRIQIILKERGI

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=348, Percent_Identity=41.3793103448276, Blast_Score=251, Evalue=3e-68,
Organism=Escherichia coli, GI1788550, Length=125, Percent_Identity=31.2, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 38652; Mature: 38652

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPSPVRVVIIDDSLLVRNIISDQIQKDSNIHVIATGKTGVDCIDLAQKMNPDVIILDVE
CCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEC
MPVMDGLTALHELQKKKLGIPVIMLSVLTQNGAEATFKALEYGAIDFVPKPSSVFQFDPE
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCEEECCCCCCCEEECHH
EIGKILKSKILAYFESRVRREVLKKVSVLAKVPVGEPHVKKSPVQAICIGTSTGGPRALQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHH
EVFSRIPEDISLPIFVVQHMPAGFTKAFAMRLNDHSKIKVKEAEDGESIEPNTGYVAPGD
HHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEECCCC
AHLSIHSKGGRKWIALSREGLVNGHRPSIEVLLNSAIEEYKSGMIGVIMTGMGKDGSAAM
CEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEE
VKVREAGGSTIAQDEQTSVIYGMNRQAVEMGGVEYIEPVTEIINRIQIILKERGI
EEEECCCCCCCCCCCCCEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVPSPVRVVIIDDSLLVRNIISDQIQKDSNIHVIATGKTGVDCIDLAQKMNPDVIILDVE
CCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEC
MPVMDGLTALHELQKKKLGIPVIMLSVLTQNGAEATFKALEYGAIDFVPKPSSVFQFDPE
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCEEECCCCCCCEEECHH
EIGKILKSKILAYFESRVRREVLKKVSVLAKVPVGEPHVKKSPVQAICIGTSTGGPRALQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHH
EVFSRIPEDISLPIFVVQHMPAGFTKAFAMRLNDHSKIKVKEAEDGESIEPNTGYVAPGD
HHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEECCCC
AHLSIHSKGGRKWIALSREGLVNGHRPSIEVLLNSAIEEYKSGMIGVIMTGMGKDGSAAM
CEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEE
VKVREAGGSTIAQDEQTSVIYGMNRQAVEMGGVEYIEPVTEIINRIQIILKERGI
EEEECCCCCCCCCCCCCEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA