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The map label for this gene is fcbD [H]

Identifier: 116327944

GI number: 116327944

Start: 1450318

End: 1451163

Strand: Direct

Name: fcbD [H]

Synonym: LBL_1233

Alternate gene names: 116327944

Gene position: 1450318-1451163 (Clockwise)

Preceding gene: 116327943

Following gene: 116327945

Centisome position: 40.13

GC content: 34.04

Gene sequence:

>846_bases
ATGAATCCTTTAGTTTCTATCGTAATTCCATGTTATAATTATGGTCGATATATTCACGAAACCGTTGAGAGTATATTGAG
GCAGAGATATAAGTATTGGGAAGTAATAATCGTAGATGATGGGTCTAACGATCCATTTACAATTTCAATTCTAGAGGAAT
ACAAGAATAAATCCGGTTTTACGGTTCTTTCTATTCCGCGTTCTGGACCTTCTACAGCACGTAATATTGGGATTGATACG
GCTCAAGGAGAGTTTATACTTCCTTTAGATTCGGACGATATGATTCACGAGGATTATCTTTTGGAGGCGATATCCGCTTA
CGAAAAGAATCCGTCTTTAGGAATCGTATATTGTGAAGCGGAGTTTTTCGGATCTATAAAAGGGAAATGGAATCTTCCTG
AATATCGTTTTCCGAATATACTTTTGGACAATTGTATATTTGTGTCCGCTGTATTTAAAAAGTCGGATTGGAAGGAAGTC
GGTGGATTTAATGAAAACATGAAAAACGAATGGGAGGATTATGATTTTTGGCTTTCATTGATTGAAAAAGGGGGAAAGGT
TTATAGAATTCCCAAGGTTTTATTTTACTATAGGATTGGGCATTCGTCCCGTTCGCAAAGATCTCTCAAACATTTTCTTC
CATTATATATGCAACTATATGAAAATCATAAAGAATTGTATTTAAAGAATATTCAATTTTTATTTCAGAGACATTTGGAG
GCTAAGCGGCTGGAAGACGAATTTTTAATTTTGACTAAAAATCCATTCGTTTACTCGTTTATAAAGATGCTGATAACTTT
TCTAAAGTATCTTTCCCTAATAAAAAGAAAATTCTTAAACGTCTGA

Upstream 100 bases:

>100_bases
CCGGGATGTTTTTTGGCAAGTTCAAAGTAAGAGATATATAAGTTGGATTATCTTTAGTGCTTCTTAAAAAGAGATATTAA
AATAATATAATTTTACCTAA

Downstream 100 bases:

>100_bases
TTCAAAATTAAATGTAAGGCTTTAGATTTCGATTAACTGTAAACGGCAGAAAGACCTTAAAAAAATCTTAAAAGAGCGAT
TTTGAAATCGAATTTCCGTA

Product: glycosyltransferase

Products: NA

Alternate protein names: CS; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase; UDP-GalNAc transferase; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase; UDP-GlcUA transferase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MNPLVSIVIPCYNYGRYIHETVESILRQRYKYWEVIIVDDGSNDPFTISILEEYKNKSGFTVLSIPRSGPSTARNIGIDT
AQGEFILPLDSDDMIHEDYLLEAISAYEKNPSLGIVYCEAEFFGSIKGKWNLPEYRFPNILLDNCIFVSAVFKKSDWKEV
GGFNENMKNEWEDYDFWLSLIEKGGKVYRIPKVLFYYRIGHSSRSQRSLKHFLPLYMQLYENHKELYLKNIQFLFQRHLE
AKRLEDEFLILTKNPFVYSFIKMLITFLKYLSLIKRKFLNV

Sequences:

>Translated_281_residues
MNPLVSIVIPCYNYGRYIHETVESILRQRYKYWEVIIVDDGSNDPFTISILEEYKNKSGFTVLSIPRSGPSTARNIGIDT
AQGEFILPLDSDDMIHEDYLLEAISAYEKNPSLGIVYCEAEFFGSIKGKWNLPEYRFPNILLDNCIFVSAVFKKSDWKEV
GGFNENMKNEWEDYDFWLSLIEKGGKVYRIPKVLFYYRIGHSSRSQRSLKHFLPLYMQLYENHKELYLKNIQFLFQRHLE
AKRLEDEFLILTKNPFVYSFIKMLITFLKYLSLIKRKFLNV
>Mature_281_residues
MNPLVSIVIPCYNYGRYIHETVESILRQRYKYWEVIIVDDGSNDPFTISILEEYKNKSGFTVLSIPRSGPSTARNIGIDT
AQGEFILPLDSDDMIHEDYLLEAISAYEKNPSLGIVYCEAEFFGSIKGKWNLPEYRFPNILLDNCIFVSAVFKKSDWKEV
GGFNENMKNEWEDYDFWLSLIEKGGKVYRIPKVLFYYRIGHSSRSQRSLKHFLPLYMQLYENHKELYLKNIQFLFQRHLE
AKRLEDEFLILTKNPFVYSFIKMLITFLKYLSLIKRKFLNV

Specific function: Catalyzes the polymerization of chondroitin, a polysaccharide composed of a repeating disaccharide of N- acetylgalactosamine (GalNAc) and glucuronic acid (GlcUA) units. Each unit has the composition in beta-(1->4)-GlcUA-beta-(1->3)- GalNAc [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. CS/HAS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787259, Length=250, Percent_Identity=26, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788372, Length=248, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790044, Length=160, Percent_Identity=27.5, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.4.1.175; =2.4.1.226 [H]

Molecular weight: Translated: 33252; Mature: 33252

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLVSIVIPCYNYGRYIHETVESILRQRYKYWEVIIVDDGSNDPFTISILEEYKNKSGF
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCEEEEEHHHHCCCCCC
TVLSIPRSGPSTARNIGIDTAQGEFILPLDSDDMIHEDYLLEAISAYEKNPSLGIVYCEA
EEEEECCCCCCCHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEH
EFFGSIKGKWNLPEYRFPNILLDNCIFVSAVFKKSDWKEVGGFNENMKNEWEDYDFWLSL
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHH
IEKGGKVYRIPKVLFYYRIGHSSRSQRSLKHFLPLYMQLYENHKELYLKNIQFLFQRHLE
HHCCCCEEEHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKRLEDEFLILTKNPFVYSFIKMLITFLKYLSLIKRKFLNV
HHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNPLVSIVIPCYNYGRYIHETVESILRQRYKYWEVIIVDDGSNDPFTISILEEYKNKSGF
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCEEEEEHHHHCCCCCC
TVLSIPRSGPSTARNIGIDTAQGEFILPLDSDDMIHEDYLLEAISAYEKNPSLGIVYCEA
EEEEECCCCCCCHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEH
EFFGSIKGKWNLPEYRFPNILLDNCIFVSAVFKKSDWKEVGGFNENMKNEWEDYDFWLSL
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHH
IEKGGKVYRIPKVLFYYRIGHSSRSQRSLKHFLPLYMQLYENHKELYLKNIQFLFQRHLE
HHCCCCEEEHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKRLEDEFLILTKNPFVYSFIKMLITFLKYLSLIKRKFLNV
HHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10818104; 11230405; 11248100 [H]