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The map label for this gene is nagB [H]

Identifier: 116327908

GI number: 116327908

Start: 1409878

End: 1410549

Strand: Direct

Name: nagB [H]

Synonym: LBL_1194

Alternate gene names: 116327908

Gene position: 1409878-1410549 (Clockwise)

Preceding gene: 116327907

Following gene: 116327909

Centisome position: 39.01

GC content: 32.29

Gene sequence:

>672_bases
TTGCACATTCTAATGCAAATAATTGAATTTTATAATAAAAAAGATTTTTTGAGCGGTTGTTTGAGTAAAATCAAGGAAAT
TTCCGATTATAAAATCCAAAATAATGGTGTGTTTCATATAGTTTTAACCGGTGGAGATACTGCTCAACTTATTTATTCTG
AATTGAAATATTTAAAAACAGATTGGTCTAAGTGGTTTTTTTATTTTGGAGATGAGAGATGTGTGCCAGAAGGCCACGTC
GATTCGAATAGTCTAATGGTTCAAAAAAGTCTGTTCGAATTTCTGCCTGTGAATGAGAAACAAATCTTTATGATTCCGGG
TTATCTTGGAGCAAAAAAAGGTGCTTTAGAATATTCAAAATCTATTCAATTAATTCCTTCTTTTGATTTGGTTCTTTTGG
GTTTAGGTGAGGATGGCCACATTGCGAGCTTATTTCCAGGTATGAATTTGTCTGAAGAAAAAGATACAATTGAAATTTAC
GACTCCCCTAAGCCTCCGAAAGAGAGAATCAGCTTGTCTTTAAGAAAAATTAATTCATCAGATTGTATTTTGATTATCGC
AAAAGGAAGAAAGAAAAAGGAAATCATTGAAAGAATCAAGATGGGTGAAACTCTACCTGTCACTTCTCTTTTTCCTAAAA
AGTCAATTGAACTCTGTTATTTTTACGACTGA

Upstream 100 bases:

>100_bases
TACAAGATTTCCTATCTGAATACGGCAGAGTTAATGAAAATTGGTTTGTTGCTTGGAAATCATTTAGTGATCAGTTGCTT
CACCCCACTTTTTAGATCTT

Downstream 100 bases:

>100_bases
CCGCTTTCGTTAAATAGAAAGGATTTTTAAATGAAAAGGATTGTGAAAAATTATATTATTAAAATAGCTTCTTTTATTAT
TTTCCTCTTGAGAAAAGCAT

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MHILMQIIEFYNKKDFLSGCLSKIKEISDYKIQNNGVFHIVLTGGDTAQLIYSELKYLKTDWSKWFFYFGDERCVPEGHV
DSNSLMVQKSLFEFLPVNEKQIFMIPGYLGAKKGALEYSKSIQLIPSFDLVLLGLGEDGHIASLFPGMNLSEEKDTIEIY
DSPKPPKERISLSLRKINSSDCILIIAKGRKKKEIIERIKMGETLPVTSLFPKKSIELCYFYD

Sequences:

>Translated_223_residues
MHILMQIIEFYNKKDFLSGCLSKIKEISDYKIQNNGVFHIVLTGGDTAQLIYSELKYLKTDWSKWFFYFGDERCVPEGHV
DSNSLMVQKSLFEFLPVNEKQIFMIPGYLGAKKGALEYSKSIQLIPSFDLVLLGLGEDGHIASLFPGMNLSEEKDTIEIY
DSPKPPKERISLSLRKINSSDCILIIAKGRKKKEIIERIKMGETLPVTSLFPKKSIELCYFYD
>Mature_223_residues
MHILMQIIEFYNKKDFLSGCLSKIKEISDYKIQNNGVFHIVLTGGDTAQLIYSELKYLKTDWSKWFFYFGDERCVPEGHV
DSNSLMVQKSLFEFLPVNEKQIFMIPGYLGAKKGALEYSKSIQLIPSFDLVLLGLGEDGHIASLFPGMNLSEEKDTIEIY
DSPKPPKERISLSLRKINSSDCILIIAKGRKKKEIIERIKMGETLPVTSLFPKKSIELCYFYD

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912586, Length=202, Percent_Identity=32.6732673267327, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI52145310, Length=226, Percent_Identity=28.7610619469027, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115533058, Length=194, Percent_Identity=28.8659793814433, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533060, Length=194, Percent_Identity=28.8659793814433, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321957, Length=188, Percent_Identity=31.9148936170213, Blast_Score=92, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6321687, Length=187, Percent_Identity=33.1550802139037, Blast_Score=92, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6324362, Length=209, Percent_Identity=32.5358851674641, Blast_Score=82, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6319918, Length=219, Percent_Identity=29.2237442922374, Blast_Score=72, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24641119, Length=217, Percent_Identity=28.110599078341, Blast_Score=88, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25553; Mature: 25553

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHILMQIIEFYNKKDFLSGCLSKIKEISDYKIQNNGVFHIVLTGGDTAQLIYSELKYLKT
CHHHHHHHHHHCCHHHHHHHHHHHHHHHCEEEECCCEEEEEEECCCHHHHHHHHHHHHHC
DWSKWFFYFGDERCVPEGHVDSNSLMVQKSLFEFLPVNEKQIFMIPGYLGAKKGALEYSK
CCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHCC
SIQLIPSFDLVLLGLGEDGHIASLFPGMNLSEEKDTIEIYDSPKPPKERISLSLRKINSS
CEEEECCCEEEEEEECCCCCEEEECCCCCCCCCCCEEEEECCCCCHHHHHEEEEEEECCC
DCILIIAKGRKKKEIIERIKMGETLPVTSLFPKKSIELCYFYD
CEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MHILMQIIEFYNKKDFLSGCLSKIKEISDYKIQNNGVFHIVLTGGDTAQLIYSELKYLKT
CHHHHHHHHHHCCHHHHHHHHHHHHHHHCEEEECCCEEEEEEECCCHHHHHHHHHHHHHC
DWSKWFFYFGDERCVPEGHVDSNSLMVQKSLFEFLPVNEKQIFMIPGYLGAKKGALEYSK
CCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHCC
SIQLIPSFDLVLLGLGEDGHIASLFPGMNLSEEKDTIEIYDSPKPPKERISLSLRKINSS
CEEEECCCEEEEEEECCCCCEEEECCCCCCCCCCCEEEEECCCCCHHHHHEEEEEEECCC
DCILIIAKGRKKKEIIERIKMGETLPVTSLFPKKSIELCYFYD
CEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]