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The map label for this gene is 116327498

Identifier: 116327498

GI number: 116327498

Start: 817900

End: 819474

Strand: Direct

Name: 116327498

Synonym: LBL_0722

Alternate gene names: NA

Gene position: 817900-819474 (Clockwise)

Preceding gene: 116327495

Following gene: 116327499

Centisome position: 22.63

GC content: 42.67

Gene sequence:

>1575_bases
ATGTGTTTTCTAAAACCGATCTTAAGACTTTTCATGATCTATGTCCTTCTTTCGAGCGTTTCTTTATATGCGGACGCAGC
GATCTTTTCCGGGCTTAAGAAATCCTTGGAAGAAAAGACGAAAACGTTTCGGATGGATAACGGACTGAGAGTTCTCATGA
TGAAACGAGAGGATTCTCCCACTATCGCCGTTTATACGAAATTTTTAGTAGGTTCCGCGGATGAAACTCCAGAGATCTCG
GGCACGGCGCATCTCTTAGAGCATATGCTTTTTAAGGGAACGAAGAATATCGGAACCACGAACTACGAAAAAGAAAAACC
GTATCTGGAACAAATCGCTGTCTGGGGAAAACGATTGGATTCTCTTCGCATTCAAGAACTGGAAATGAAATCCAGAGGAG
AAGAACCGTCTGCGGAATTTAAGGATCAAATCGACGTTTTGAGTAAACGATTCTCCGCGCTTCTGGAACTTCATCGTAAA
TTCGTAATATCGAACGAAGACAATTATATCTATTCCAGAAACGGAGGGGTGGGATTCAACGCATATACTTCGAACGACGT
TACCAACTATCAGATTCTTCTTCCCGCAAATCGTTTGGAAATTTGGGCTAAACTTGAATCGGATCGATTGAAAAATCCCA
TATTCAGAGAATATTATACGGAAAGAGACGTGGTTCTGGAAGAAAGAAGAATGCGCGTCGAAAATAGAGGGATGGGAATC
TTAAGGGAAAAATATTTGGATGCGGCTTTTCCGGAAGGTCATCCGTACCGAATGCCTGTGATCGGTTATGAGAAGAATTT
GGGATTTTTGGATTTGGAAAATACCCGAACGTTTTTTAGGAATTACTACGATCCTCAAAGAATGGTGATTGCCGTTGTGG
GTTCTTTGGATTTCGAAAAGACCGAAAAAATTCTTCGCAACTATTTCGGAGATTTGAAAAAAGGAAGTGCTCCAATTTCA
AAAAAAGCGACCGAAGCCGGATGGACCGGACCGAAGTTCGTGTCCGTGGTTCATCCGAGCGCTCCTTCTAAAATCATCGG
CTTTCATAAACCCGCTTTTCCTCATCCGGACGACGCAGTATTTAGCGTGATTGATACTCTGCTCGCGGAAGGAGAATCCG
GAAGACTTTTCAAAAAGCTGGTTTTAGAGGAGCAAGTCGCTCAAGGGGTGTATTGCTGGAACGGAGATCCGGGCGATAGG
CTTTCCAATTTGTTTTCGATCTATATCACCAACAATCAAAATGCGGATCAAAAGAAAGTGGAGAGTATCGTTCAAGGAGA
ACTAGACCGGTTGAAAACGGAACTCATCACTTCGGAAGTTTTATTTAAAATCAAGAATCAGATCTTAGGTGAATATCTAC
GTGCCTTGGACGATAACGGCAAATTGGCGGATGTTCTTTCCCTTTATCAATTGTTATACGGAGATTGGAAGGAACTTTTG
AGGGGTTACGAAGAATTGGATACGGTGACTCCGGAAGATGTTAGGAGGGTCGCAAAAAAATATTTCGTACCCGAAAACAG
AACGATCGCGGAATTGAATCCGCCCGTAAAAGAAACAAAAGGGATCGGAAACTAG

Upstream 100 bases:

>100_bases
GCCGCATGAGACAAACGTTTCCGAATCAACTTGAAAAGGAAGCAGGATTTTTCCGGGAACTTTCTGGACACCAGGTTCCA
AAGGGGAAAGTCTGTAAGCT

Downstream 100 bases:

>100_bases
GATGAAAAACTTCGAAAGAACTATGATCCATAAAACAGACAGTCTACGGAGTGTTCCGCAACAGAATGATATTTTTTGTG
AGAACTCGTCTTTCGGCCCA

Product: Zn-dependent peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MCFLKPILRLFMIYVLLSSVSLYADAAIFSGLKKSLEEKTKTFRMDNGLRVLMMKREDSPTIAVYTKFLVGSADETPEIS
GTAHLLEHMLFKGTKNIGTTNYEKEKPYLEQIAVWGKRLDSLRIQELEMKSRGEEPSAEFKDQIDVLSKRFSALLELHRK
FVISNEDNYIYSRNGGVGFNAYTSNDVTNYQILLPANRLEIWAKLESDRLKNPIFREYYTERDVVLEERRMRVENRGMGI
LREKYLDAAFPEGHPYRMPVIGYEKNLGFLDLENTRTFFRNYYDPQRMVIAVVGSLDFEKTEKILRNYFGDLKKGSAPIS
KKATEAGWTGPKFVSVVHPSAPSKIIGFHKPAFPHPDDAVFSVIDTLLAEGESGRLFKKLVLEEQVAQGVYCWNGDPGDR
LSNLFSIYITNNQNADQKKVESIVQGELDRLKTELITSEVLFKIKNQILGEYLRALDDNGKLADVLSLYQLLYGDWKELL
RGYEELDTVTPEDVRRVAKKYFVPENRTIAELNPPVKETKGIGN

Sequences:

>Translated_524_residues
MCFLKPILRLFMIYVLLSSVSLYADAAIFSGLKKSLEEKTKTFRMDNGLRVLMMKREDSPTIAVYTKFLVGSADETPEIS
GTAHLLEHMLFKGTKNIGTTNYEKEKPYLEQIAVWGKRLDSLRIQELEMKSRGEEPSAEFKDQIDVLSKRFSALLELHRK
FVISNEDNYIYSRNGGVGFNAYTSNDVTNYQILLPANRLEIWAKLESDRLKNPIFREYYTERDVVLEERRMRVENRGMGI
LREKYLDAAFPEGHPYRMPVIGYEKNLGFLDLENTRTFFRNYYDPQRMVIAVVGSLDFEKTEKILRNYFGDLKKGSAPIS
KKATEAGWTGPKFVSVVHPSAPSKIIGFHKPAFPHPDDAVFSVIDTLLAEGESGRLFKKLVLEEQVAQGVYCWNGDPGDR
LSNLFSIYITNNQNADQKKVESIVQGELDRLKTELITSEVLFKIKNQILGEYLRALDDNGKLADVLSLYQLLYGDWKELL
RGYEELDTVTPEDVRRVAKKYFVPENRTIAELNPPVKETKGIGN
>Mature_524_residues
MCFLKPILRLFMIYVLLSSVSLYADAAIFSGLKKSLEEKTKTFRMDNGLRVLMMKREDSPTIAVYTKFLVGSADETPEIS
GTAHLLEHMLFKGTKNIGTTNYEKEKPYLEQIAVWGKRLDSLRIQELEMKSRGEEPSAEFKDQIDVLSKRFSALLELHRK
FVISNEDNYIYSRNGGVGFNAYTSNDVTNYQILLPANRLEIWAKLESDRLKNPIFREYYTERDVVLEERRMRVENRGMGI
LREKYLDAAFPEGHPYRMPVIGYEKNLGFLDLENTRTFFRNYYDPQRMVIAVVGSLDFEKTEKILRNYFGDLKKGSAPIS
KKATEAGWTGPKFVSVVHPSAPSKIIGFHKPAFPHPDDAVFSVIDTLLAEGESGRLFKKLVLEEQVAQGVYCWNGDPGDR
LSNLFSIYITNNQNADQKKVESIVQGELDRLKTELITSEVLFKIKNQILGEYLRALDDNGKLADVLSLYQLLYGDWKELL
RGYEELDTVTPEDVRRVAKKYFVPENRTIAELNPPVKETKGIGN

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: NA

Molecular weight: Translated: 60063; Mature: 60063

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCFLKPILRLFMIYVLLSSVSLYADAAIFSGLKKSLEEKTKTFRMDNGLRVLMMKREDSP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
TIAVYTKFLVGSADETPEISGTAHLLEHMLFKGTKNIGTTNYEKEKPYLEQIAVWGKRLD
EEEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
SLRIQELEMKSRGEEPSAEFKDQIDVLSKRFSALLELHRKFVISNEDNYIYSRNGGVGFN
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCEEC
AYTSNDVTNYQILLPANRLEIWAKLESDRLKNPIFREYYTERDVVLEERRMRVENRGMGI
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHHHHHHHCCCHH
LREKYLDAAFPEGHPYRMPVIGYEKNLGFLDLENTRTFFRNYYDPQRMVIAVVGSLDFEK
HHHHHHHHCCCCCCCEECCEEEEECCCCEEECCHHHHHHHHCCCHHHHHHHHHHCCCHHH
TEKILRNYFGDLKKGSAPISKKATEAGWTGPKFVSVVHPSAPSKIIGFHKPAFPHPDDAV
HHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHH
FSVIDTLLAEGESGRLFKKLVLEEQVAQGVYCWNGDPGDRLSNLFSIYITNNQNADQKKV
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHCEEEEEEECCCCCHHHHH
ESIVQGELDRLKTELITSEVLFKIKNQILGEYLRALDDNGKLADVLSLYQLLYGDWKELL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
RGYEELDTVTPEDVRRVAKKYFVPENRTIAELNPPVKETKGIGN
HHHHHHCCCCHHHHHHHHHHHCCCCCCEEECCCCCHHHCCCCCC
>Mature Secondary Structure
MCFLKPILRLFMIYVLLSSVSLYADAAIFSGLKKSLEEKTKTFRMDNGLRVLMMKREDSP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
TIAVYTKFLVGSADETPEISGTAHLLEHMLFKGTKNIGTTNYEKEKPYLEQIAVWGKRLD
EEEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
SLRIQELEMKSRGEEPSAEFKDQIDVLSKRFSALLELHRKFVISNEDNYIYSRNGGVGFN
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCEEC
AYTSNDVTNYQILLPANRLEIWAKLESDRLKNPIFREYYTERDVVLEERRMRVENRGMGI
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHHHHHHHCCCHH
LREKYLDAAFPEGHPYRMPVIGYEKNLGFLDLENTRTFFRNYYDPQRMVIAVVGSLDFEK
HHHHHHHHCCCCCCCEECCEEEEECCCCEEECCHHHHHHHHCCCHHHHHHHHHHCCCHHH
TEKILRNYFGDLKKGSAPISKKATEAGWTGPKFVSVVHPSAPSKIIGFHKPAFPHPDDAV
HHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHH
FSVIDTLLAEGESGRLFKKLVLEEQVAQGVYCWNGDPGDRLSNLFSIYITNNQNADQKKV
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHCEEEEEEECCCCCHHHHH
ESIVQGELDRLKTELITSEVLFKIKNQILGEYLRALDDNGKLADVLSLYQLLYGDWKELL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
RGYEELDTVTPEDVRRVAKKYFVPENRTIAELNPPVKETKGIGN
HHHHHHCCCCHHHHHHHHHHHCCCCCCEEECCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]