Click here to switch to the map view.

The map label for this gene is benK [H]

Identifier: 116248890

GI number: 116248890

Start: 227554

End: 228966

Strand: Direct

Name: benK [H]

Synonym: pRL120220

Alternate gene names: 116248890

Gene position: 227554-228966 (Clockwise)

Preceding gene: 116248889

Following gene: 116248891

Centisome position: 26.16

GC content: 58.24

Gene sequence:

>1413_bases
TTGCGGGTGAGTCTGGCGCTGGGAGGAACCACGCCGGCAACGATCCAGGAGGATTTGTACACGGATCGACGCGGACCTGC
CGCTTGGCAGGAGCGTACTTCCTGTACGCAAATGTATGGGGAGGGAAAATTGGCCATACAAGATCTCGCTATTATCAACG
AACGCGTTCGCAGCCCGAATATCATCATCGCCCTTTGCGGTCTGCTGATCCTATTCGACGGCTATGACCTGATCGTTTAC
GGCGCAGTCGCGCCGGCGTTGCTCGGTGAAGCCAGTTGGGGCCTGACTCCGGGCATGGTCGGACGGGCTGCCTCCATCAC
CCTGTTCGGTATGCTGCTGGGCGCTCTCGTTGCCGGAACACTTGCTGACAGGATAGGTCGTCGCAAGGTCATCATCGGCA
GTCTGCTGAGCTTTTCCGTGATGATGATCGGTAGCGGTCTTGCGCCGAACTTTCTCGCTTTCGAGGGAACACGCTTTCTC
GCCGGCCTGGGCCTTGGAGCTCTTTTTCCCACGGTAACCGCTCTAATCATCGAGTTTTCTCCGCCGAAACGGAAGGCAAT
GGCCTATTCGATTGCTCTTCTGGGTTACCTGGCCGGCGGCATCATTTCGGGTATCCTCGGAATGCTGCTGATACAGAAAT
ACGGATGGCGTCCACTGATGATTATCGGCGGTGCACCGATCCTGCTTCTGCCTTTCTTCATCCGTCTCATACCCGAGTCC
CCCGAATGGCTGGCAACGAAGAACCGCCAGACCGAAGCCAACCAGATCGCAAACCAGTACGGGCTGCCCAATCCCGTAGC
CAGGCCTGCTGCATCACGCCAGGTCGGCATCCGCTCGCTGTTTTCTGAAGGTCGCCTGCTGCCGACATTGAACGCATGGG
GCATTCACTTCTGTTCGCTTCTGCTCACATTCGGCATGGTCAACTGGCTTCCGACCATCATGAACAAGATGGGCTATGAC
CTCGGTTCCGCCCTCCTCTTCTCCGTAACGCTCAATCTCGGAGCGGCCGTCGGCCTCCTGATCGGCGCAAGGATTGCCGA
CCGCGGAAACGTCAAAATAGTCGTGGCAGGCATGTTTCTTCTCGGAGCCTGCTCGATCTGGTTGCTGACGCAAGTGGATC
AGGGCCTCCAGGTTTATGGTCTCGTCGCACTTGCCGGTACGGGAACGATCGGCACGCAGATCCTCGCCAACGTTCTCGTT
GGAAACCTCTATCCGGTCGAAATCCGTGGAACCGGCCTTGGCTTCTCGCTCGGCATCGGCCGTATCGGCGGCATGATAGG
ACCGGCCATCGGCGGTGCGGTTCTGGGTGCGGGCCTGGCTCCGCAGTGGAACTTCTACATCTTCGCATCGGTCGGAGTCT
TGGGATGCGTCCTCGCGCTCATGACGTTGCTGTATCGCAAAAAGGCTGATTGA

Upstream 100 bases:

>100_bases
GTCCGGAAAGGGGAAAGTTGCGAACTGAAAAGTTTGCAGTTGCAAATATTTTATTCGCAAGTATTTAATAGCGTGTCATC
GTTGTCTTGACATAGCCCGT

Downstream 100 bases:

>100_bases
CGGCCAGATTGTCGGCAGGTCTGACATCCAGAACCTGCCGGCAATGCAAACTTTGCGAAGCCAATGCCTGATCATCGCCG
ACGGCTTTTACGCGGTCACC

Product: MFS family permease

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MRVSLALGGTTPATIQEDLYTDRRGPAAWQERTSCTQMYGEGKLAIQDLAIINERVRSPNIIIALCGLLILFDGYDLIVY
GAVAPALLGEASWGLTPGMVGRAASITLFGMLLGALVAGTLADRIGRRKVIIGSLLSFSVMMIGSGLAPNFLAFEGTRFL
AGLGLGALFPTVTALIIEFSPPKRKAMAYSIALLGYLAGGIISGILGMLLIQKYGWRPLMIIGGAPILLLPFFIRLIPES
PEWLATKNRQTEANQIANQYGLPNPVARPAASRQVGIRSLFSEGRLLPTLNAWGIHFCSLLLTFGMVNWLPTIMNKMGYD
LGSALLFSVTLNLGAAVGLLIGARIADRGNVKIVVAGMFLLGACSIWLLTQVDQGLQVYGLVALAGTGTIGTQILANVLV
GNLYPVEIRGTGLGFSLGIGRIGGMIGPAIGGAVLGAGLAPQWNFYIFASVGVLGCVLALMTLLYRKKAD

Sequences:

>Translated_470_residues
MRVSLALGGTTPATIQEDLYTDRRGPAAWQERTSCTQMYGEGKLAIQDLAIINERVRSPNIIIALCGLLILFDGYDLIVY
GAVAPALLGEASWGLTPGMVGRAASITLFGMLLGALVAGTLADRIGRRKVIIGSLLSFSVMMIGSGLAPNFLAFEGTRFL
AGLGLGALFPTVTALIIEFSPPKRKAMAYSIALLGYLAGGIISGILGMLLIQKYGWRPLMIIGGAPILLLPFFIRLIPES
PEWLATKNRQTEANQIANQYGLPNPVARPAASRQVGIRSLFSEGRLLPTLNAWGIHFCSLLLTFGMVNWLPTIMNKMGYD
LGSALLFSVTLNLGAAVGLLIGARIADRGNVKIVVAGMFLLGACSIWLLTQVDQGLQVYGLVALAGTGTIGTQILANVLV
GNLYPVEIRGTGLGFSLGIGRIGGMIGPAIGGAVLGAGLAPQWNFYIFASVGVLGCVLALMTLLYRKKAD
>Mature_470_residues
MRVSLALGGTTPATIQEDLYTDRRGPAAWQERTSCTQMYGEGKLAIQDLAIINERVRSPNIIIALCGLLILFDGYDLIVY
GAVAPALLGEASWGLTPGMVGRAASITLFGMLLGALVAGTLADRIGRRKVIIGSLLSFSVMMIGSGLAPNFLAFEGTRFL
AGLGLGALFPTVTALIIEFSPPKRKAMAYSIALLGYLAGGIISGILGMLLIQKYGWRPLMIIGGAPILLLPFFIRLIPES
PEWLATKNRQTEANQIANQYGLPNPVARPAASRQVGIRSLFSEGRLLPTLNAWGIHFCSLLLTFGMVNWLPTIMNKMGYD
LGSALLFSVTLNLGAAVGLLIGARIADRGNVKIVVAGMFLLGACSIWLLTQVDQGLQVYGLVALAGTGTIGTQILANVLV
GNLYPVEIRGTGLGFSLGIGRIGGMIGPAIGGAVLGAGLAPQWNFYIFASVGVLGCVLALMTLLYRKKAD

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=404, Percent_Identity=25.990099009901, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI166064021, Length=341, Percent_Identity=26.6862170087977, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI8923870, Length=384, Percent_Identity=25.5208333333333, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI7662270, Length=247, Percent_Identity=25.9109311740891, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI24497476, Length=378, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI20070188, Length=378, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI90669191, Length=376, Percent_Identity=25.2659574468085, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI166197673, Length=363, Percent_Identity=28.099173553719, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI24497497, Length=349, Percent_Identity=25.5014326647564, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI216548223, Length=218, Percent_Identity=24.7706422018349, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI213021148, Length=448, Percent_Identity=22.3214285714286, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI24497480, Length=152, Percent_Identity=32.2368421052632, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI24497478, Length=152, Percent_Identity=32.2368421052632, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI262399383, Length=176, Percent_Identity=26.7045454545455, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081723, Length=387, Percent_Identity=29.1989664082687, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI87082159, Length=370, Percent_Identity=28.6486486486486, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788074, Length=357, Percent_Identity=27.7310924369748, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788068, Length=344, Percent_Identity=26.7441860465116, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI87082231, Length=411, Percent_Identity=24.330900243309, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786229, Length=374, Percent_Identity=25.4010695187166, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87082404, Length=377, Percent_Identity=22.2811671087533, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32564663, Length=396, Percent_Identity=24.7474747474747, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71984734, Length=415, Percent_Identity=24.3373493975904, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24640198, Length=444, Percent_Identity=22.2972972972973, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24640196, Length=444, Percent_Identity=22.2972972972973, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24640200, Length=444, Percent_Identity=22.2972972972973, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24668440, Length=368, Percent_Identity=27.9891304347826, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24668456, Length=399, Percent_Identity=28.0701754385965, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19922874, Length=395, Percent_Identity=21.7721518987342, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19922616, Length=414, Percent_Identity=24.3961352657005, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24649616, Length=373, Percent_Identity=22.7882037533512, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221330907, Length=177, Percent_Identity=26.5536723163842, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49623; Mature: 49623

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSLALGGTTPATIQEDLYTDRRGPAAWQERTSCTQMYGEGKLAIQDLAIINERVRSPN
CEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
IIIALCGLLILFDGYDLIVYGAVAPALLGEASWGLTPGMVGRAASITLFGMLLGALVAGT
HHHHHHHHHHHHCCCHHEEHHHHHHHHHCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHH
LADRIGRRKVIIGSLLSFSVMMIGSGLAPNFLAFEGTRFLAGLGLGALFPTVTALIIEFS
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHCHHHHHHHHHHHHEECC
PPKRKAMAYSIALLGYLAGGIISGILGMLLIQKYGWRPLMIIGGAPILLLPFFIRLIPES
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCC
PEWLATKNRQTEANQIANQYGLPNPVARPAASRQVGIRSLFSEGRLLPTLNAWGIHFCSL
CHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LLTFGMVNWLPTIMNKMGYDLGSALLFSVTLNLGAAVGLLIGARIADRGNVKIVVAGMFL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHH
LGACSIWLLTQVDQGLQVYGLVALAGTGTIGTQILANVLVGNLYPVEIRGTGLGFSLGIG
HHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHCCEEEEEEEECCCCHHHCHH
RIGGMIGPAIGGAVLGAGLAPQWNFYIFASVGVLGCVLALMTLLYRKKAD
HHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVSLALGGTTPATIQEDLYTDRRGPAAWQERTSCTQMYGEGKLAIQDLAIINERVRSPN
CEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
IIIALCGLLILFDGYDLIVYGAVAPALLGEASWGLTPGMVGRAASITLFGMLLGALVAGT
HHHHHHHHHHHHCCCHHEEHHHHHHHHHCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHH
LADRIGRRKVIIGSLLSFSVMMIGSGLAPNFLAFEGTRFLAGLGLGALFPTVTALIIEFS
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHCHHHHHHHHHHHHEECC
PPKRKAMAYSIALLGYLAGGIISGILGMLLIQKYGWRPLMIIGGAPILLLPFFIRLIPES
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCC
PEWLATKNRQTEANQIANQYGLPNPVARPAASRQVGIRSLFSEGRLLPTLNAWGIHFCSL
CHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LLTFGMVNWLPTIMNKMGYDLGSALLFSVTLNLGAAVGLLIGARIADRGNVKIVVAGMFL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHH
LGACSIWLLTQVDQGLQVYGLVALAGTGTIGTQILANVLVGNLYPVEIRGTGLGFSLGIG
HHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHCCEEEEEEEECCCCHHHCHH
RIGGMIGPAIGGAVLGAGLAPQWNFYIFASVGVLGCVLALMTLLYRKKAD
HHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]