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The map label for this gene is 116248882

Identifier: 116248882

GI number: 116248882

Start: 220723

End: 221769

Strand: Direct

Name: 116248882

Synonym: pRL120212

Alternate gene names: NA

Gene position: 220723-221769 (Clockwise)

Preceding gene: 116248880

Following gene: 116248889

Centisome position: 25.37

GC content: 62.94

Gene sequence:

>1047_bases
ATGAAGCGCCCGCGCCGCCCACTGCCCTTGCTCGACGAATCTCACTCAACGCTGCAGTCTCGTCCGATCCGCAAGCGCGA
TCCTGACCAGCCCAGTCTGCCCTTCGATCCTATGCCGTCGCGCGTCGAGCCCTGCCTTGCACTGCTGAAGCCGACTGTGC
CCGTCGGGCCGGATTGGCTCTACGAGGTGAAGCTGGATGGCTATCGATTGGCAATCCACGTTGAGCCGAAGGGCGTGCGG
GTCATCACCCGCGGCGGCCATGACTGGACCCACCGCTTCCCCACCATCGCCGCGGCAGCCAAAGAGCTTGGCGTAGCAAC
CGCCATTCTCGATGGCGAGGCCGTTGTACTCGATGATCACGGCCGCTCGGATTTTGGCGCCCTGCAGCGTTCGCTCGGCG
GGCGGGGCGGCAAGCGAGTATCGACCGAGTCGATCCTCGTCGCCTTCGACCTTCTCTATCTCGATGGACACGATCTGACC
GGCACCGAGCTTGAGGTACGCCGGCATCTGCTTGAAGACCTGATACCGGAAGGCGATGATCGAGCGATCCGACTCTCCGA
GGAGATAGAGCTGCCGGCAGAAGAACTCCTCGAGCACGCCTGCCATCATCATCTGGAAGGCATCATCGCCAAGCATCGCG
ACCGGCCCTACGGCAGTGGCCGCACGGGCGACTGGCTGAAGATCAAATGCGTGCAGAGCGAGAGCTTCATGGTCGTCGGT
TATGAGCAGTCCGCATCCGCCCGCGGCGGCATCGGCAGGCTGCTGCTGGCCGGCAGACGAGGCCTCGACTGGATCTACGT
TGGCTCCGTCGGAACCGGTTTCGGTGCCAGCGATGCTGAATACCTGAAAAAGACGCTAGACCGGTTGAAGACGAGCCGGC
CGGTCGTTCCGCTGAAGGGCAATCGCCTCGTCCTCGTGCAGCCGACGCTGATTGCCGAGATCGAGTTTCGCGGCTGGACG
GATGACGGCAATCTCCGCCATGCCTCGTACAAGGGGCTGCGCGAGGTTCAGGACAACGCCGCTGTCTTCGAAATGACCTA
CATCTGA

Upstream 100 bases:

>100_bases
AAAAGCAGGGGCCGGCACCGGGCAATGTTGTCAGAATCATGAGTGCTGGGCGTAAGCCGGTCGAAGTGGAAAACGGCTCG
GGGAGGCGTCGGACTTAATC

Downstream 100 bases:

>100_bases
TCGCTTTCAGCAGGTCAAAACGCCGATCAGAGACTCTCCAGAAGAAGCCCAAGACTGGGCCGCCATTCGAATATATCGAC
GCTCGCGTAAACGCCGGAGC

Product: putative DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKRPRRPLPLLDESHSTLQSRPIRKRDPDQPSLPFDPMPSRVEPCLALLKPTVPVGPDWLYEVKLDGYRLAIHVEPKGVR
VITRGGHDWTHRFPTIAAAAKELGVATAILDGEAVVLDDHGRSDFGALQRSLGGRGGKRVSTESILVAFDLLYLDGHDLT
GTELEVRRHLLEDLIPEGDDRAIRLSEEIELPAEELLEHACHHHLEGIIAKHRDRPYGSGRTGDWLKIKCVQSESFMVVG
YEQSASARGGIGRLLLAGRRGLDWIYVGSVGTGFGASDAEYLKKTLDRLKTSRPVVPLKGNRLVLVQPTLIAEIEFRGWT
DDGNLRHASYKGLREVQDNAAVFEMTYI

Sequences:

>Translated_348_residues
MKRPRRPLPLLDESHSTLQSRPIRKRDPDQPSLPFDPMPSRVEPCLALLKPTVPVGPDWLYEVKLDGYRLAIHVEPKGVR
VITRGGHDWTHRFPTIAAAAKELGVATAILDGEAVVLDDHGRSDFGALQRSLGGRGGKRVSTESILVAFDLLYLDGHDLT
GTELEVRRHLLEDLIPEGDDRAIRLSEEIELPAEELLEHACHHHLEGIIAKHRDRPYGSGRTGDWLKIKCVQSESFMVVG
YEQSASARGGIGRLLLAGRRGLDWIYVGSVGTGFGASDAEYLKKTLDRLKTSRPVVPLKGNRLVLVQPTLIAEIEFRGWT
DDGNLRHASYKGLREVQDNAAVFEMTYI
>Mature_348_residues
MKRPRRPLPLLDESHSTLQSRPIRKRDPDQPSLPFDPMPSRVEPCLALLKPTVPVGPDWLYEVKLDGYRLAIHVEPKGVR
VITRGGHDWTHRFPTIAAAAKELGVATAILDGEAVVLDDHGRSDFGALQRSLGGRGGKRVSTESILVAFDLLYLDGHDLT
GTELEVRRHLLEDLIPEGDDRAIRLSEEIELPAEELLEHACHHHLEGIIAKHRDRPYGSGRTGDWLKIKCVQSESFMVVG
YEQSASARGGIGRLLLAGRRGLDWIYVGSVGTGFGASDAEYLKKTLDRLKTSRPVVPLKGNRLVLVQPTLIAEIEFRGWT
DDGNLRHASYKGLREVQDNAAVFEMTYI

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 38717; Mature: 38717

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPRRPLPLLDESHSTLQSRPIRKRDPDQPSLPFDPMPSRVEPCLALLKPTVPVGPDWL
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEE
YEVKLDGYRLAIHVEPKGVRVITRGGHDWTHRFPTIAAAAKELGVATAILDGEAVVLDDH
EEEEECCEEEEEEECCCCEEEEEECCCCHHHHCHHHHHHHHHHCEEEEEECCCEEEEECC
GRSDFGALQRSLGGRGGKRVSTESILVAFDLLYLDGHDLTGTELEVRRHLLEDLIPEGDD
CCCHHHHHHHHHCCCCCCEECHHHEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
RAIRLSEEIELPAEELLEHACHHHLEGIIAKHRDRPYGSGRTGDWLKIKCVQSESFMVVG
CEEEECHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEE
YEQSASARGGIGRLLLAGRRGLDWIYVGSVGTGFGASDAEYLKKTLDRLKTSRPVVPLKG
ECCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECC
NRLVLVQPTLIAEIEFRGWTDDGNLRHASYKGLREVQDNAAVFEMTYI
CEEEEECCCEEEEEEEECCCCCCCEEHHHHHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure
MKRPRRPLPLLDESHSTLQSRPIRKRDPDQPSLPFDPMPSRVEPCLALLKPTVPVGPDWL
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEE
YEVKLDGYRLAIHVEPKGVRVITRGGHDWTHRFPTIAAAAKELGVATAILDGEAVVLDDH
EEEEECCEEEEEEECCCCEEEEEECCCCHHHHCHHHHHHHHHHCEEEEEECCCEEEEECC
GRSDFGALQRSLGGRGGKRVSTESILVAFDLLYLDGHDLTGTELEVRRHLLEDLIPEGDD
CCCHHHHHHHHHCCCCCCEECHHHEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
RAIRLSEEIELPAEELLEHACHHHLEGIIAKHRDRPYGSGRTGDWLKIKCVQSESFMVVG
CEEEECHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEE
YEQSASARGGIGRLLLAGRRGLDWIYVGSVGTGFGASDAEYLKKTLDRLKTSRPVVPLKG
ECCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECC
NRLVLVQPTLIAEIEFRGWTDDGNLRHASYKGLREVQDNAAVFEMTYI
CEEEEECCCEEEEEEEECCCCCCCEEHHHHHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]