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The map label for this gene is nudL [H]

Identifier: 114799866

GI number: 114799866

Start: 339131

End: 339754

Strand: Direct

Name: nudL [H]

Synonym: HNE_0344

Alternate gene names: 114799866

Gene position: 339131-339754 (Clockwise)

Preceding gene: 114798915

Following gene: 114798320

Centisome position: 9.15

GC content: 63.62

Gene sequence:

>624_bases
ATGGCCTGGCAAAACCTTGATGACTTTGTAGATCGCGTCACCGCGAAGCTCGACCCGCCCGCCGGGCAGGGGCGCCTCAC
CGAAATGGGCGACATGGATTTCCTCACGCCCGAGGAAGTCGCCATCATCCGCCCGGCCGCTGTTCTCTTCGGCGTTATCC
CCCGCAAGGAAGGCCCCACCGCGCTGCTCACCCTGCGCCCCACCACAATGGCAGACCATGCCGGCCAGGTCGCGCTGCCC
GGCGGCAAGGTGGACCCGATTGATCTGGATGAAGTCGCCGCTGCCCTGCGCGAAGCGCATGAAGAAGTCGGCGCGCATCC
CGATGATGTCGATGTGCTGGGCAAGGCCTCGCCCTACATCACCGGCACGCGCTACCGCATCACGCCGGTCGTCGGCCTCC
TTCCGGCAGACTTCATACCCATCCCGGAGCCCGGCGAAGTGGCCGCCATCTTCGAGACCCCGCTCGAGCTGTTGATGAAC
CCCAAAAGCTACACGACGGGCCAGGCCTTCTACAAAGGCGCCCACCGCGAATATTACGAAATGCCTTATAATGGCTTCCG
CATCTGGGGCGTTACCGCCGGCATTATCCGCCGCCTCTACCAGACGCTCTACGAAAGCGATTGA

Upstream 100 bases:

>100_bases
GGTCGAACTGGCCGTTCCGGCGCCAAATGACAGCAATTTGCTCGGCGTGTGGAGCAAAGGGAGTTTCTTTCCGCTCGGAC
CTGTGGCTTGAGACCTGCCG

Downstream 100 bases:

>100_bases
GCCGCGCGGCGCCTTCAGGGTTTCTCAAACGCTTTCAGAGCCCTATGTAAGCTCTAGTGTTACAATGTGGGGAGAAGCAC
CGACATGGCCGGACGGCTGC

Product: NUDIX family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MAWQNLDDFVDRVTAKLDPPAGQGRLTEMGDMDFLTPEEVAIIRPAAVLFGVIPRKEGPTALLTLRPTTMADHAGQVALP
GGKVDPIDLDEVAAALREAHEEVGAHPDDVDVLGKASPYITGTRYRITPVVGLLPADFIPIPEPGEVAAIFETPLELLMN
PKSYTTGQAFYKGAHREYYEMPYNGFRIWGVTAGIIRRLYQTLYESD

Sequences:

>Translated_207_residues
MAWQNLDDFVDRVTAKLDPPAGQGRLTEMGDMDFLTPEEVAIIRPAAVLFGVIPRKEGPTALLTLRPTTMADHAGQVALP
GGKVDPIDLDEVAAALREAHEEVGAHPDDVDVLGKASPYITGTRYRITPVVGLLPADFIPIPEPGEVAAIFETPLELLMN
PKSYTTGQAFYKGAHREYYEMPYNGFRIWGVTAGIIRRLYQTLYESD
>Mature_206_residues
AWQNLDDFVDRVTAKLDPPAGQGRLTEMGDMDFLTPEEVAIIRPAAVLFGVIPRKEGPTALLTLRPTTMADHAGQVALPG
GKVDPIDLDEVAAALREAHEEVGAHPDDVDVLGKASPYITGTRYRITPVVGLLPADFIPIPEPGEVAAIFETPLELLMNP
KSYTTGQAFYKGAHREYYEMPYNGFRIWGVTAGIIRRLYQTLYESD

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=147, Percent_Identity=38.7755102040816, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1788115, Length=156, Percent_Identity=42.3076923076923, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 22723; Mature: 22592

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWQNLDDFVDRVTAKLDPPAGQGRLTEMGDMDFLTPEEVAIIRPAAVLFGVIPRKEGPT
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHEEECHHHHHHHHCCCCCCCE
ALLTLRPTTMADHAGQVALPGGKVDPIDLDEVAAALREAHEEVGAHPDDVDVLGKASPYI
EEEEECCCHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCE
TGTRYRITPVVGLLPADFIPIPEPGEVAAIFETPLELLMNPKSYTTGQAFYKGAHREYYE
ECCEEEECHHHECCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHH
MPYNGFRIWGVTAGIIRRLYQTLYESD
CCCCCEEEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AWQNLDDFVDRVTAKLDPPAGQGRLTEMGDMDFLTPEEVAIIRPAAVLFGVIPRKEGPT
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHEEECHHHHHHHHCCCCCCCE
ALLTLRPTTMADHAGQVALPGGKVDPIDLDEVAAALREAHEEVGAHPDDVDVLGKASPYI
EEEEECCCHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCE
TGTRYRITPVVGLLPADFIPIPEPGEVAAIFETPLELLMNPKSYTTGQAFYKGAHREYYE
ECCEEEECHHHECCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHH
MPYNGFRIWGVTAGIIRRLYQTLYESD
CCCCCEEEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]