Click here to switch to the map view.

The map label for this gene is dapD [H]

Identifier: 114799814

GI number: 114799814

Start: 418669

End: 419496

Strand: Direct

Name: dapD [H]

Synonym: HNE_0421

Alternate gene names: 114799814

Gene position: 418669-419496 (Clockwise)

Preceding gene: 114797054

Following gene: 114799481

Centisome position: 11.3

GC content: 65.22

Gene sequence:

>828_bases
ATGACCGACGCCCTTGCCCGTGTAATCGATGCTGCCTGGGAGGGCCGTGACCTCCTCTCCACCTCGACCACCGGTGAAGT
GCGCGACGCGGTCGACGCCGCCATCAGCCTGCTCGACAGCGGCGAAGCCCGCGTGGCCAGCAAGGAGGCCGATGGCAGCT
GGACCGTGCATCAATGGCTGAAGAAAGCCGTGCTGCTCTCCTTCCGCCTCAATGCCAATGGCGTAATGGGCGGCTCGCCC
GCCGGTGGCAACTGGTGGGACAAGGTGCCCTCCAAGTTTGAAGGCTGGGGCGAAAAGGAATTCCAGGAAGCCGGCTTCCG
CGCCGTCCCGCCGGCAGCTGTGCGCCGCGGCGCCTTCGTGGCAAAGAATGCGGTCCTGATGCCGTCTTACGTGAATATCG
GCGCCTATGTCGGCGAAGGCACGATGATCGACACCTGGGCCTCGGTCGGCTCTTGCGCGCAGGTCGGCGCCAACTGCCAC
ATCTCAGCGGGCACCGGCATCGGCGGCGTGCTGGAACCGCTGCAGGCCAACCCCACGATCATCGAGGACAACTGCTTCAT
CGGTGCGCGCTCCGAAGTGGTTGAAGGTGTCGTCGTCGGCGAAGGCTCTGTCCTCGCCATGGGCGTGTTCATCACGCAGA
GCACCAAGATCGTCTACCGCAGCACCGGCGAGATCATCTATGGCAAGGTCCCGCCATACTCCGTCGTCGTGCCCGGCACG
CTGCCCGATCCCAAAGGCGGTCCCTCGCTCGCCTGCGCCGTGATCGTGAAAACGGTCGACGCGCAGACCCGCTCGAAAAC
CGGCGTCAACGAACTGCTCCGCGACTAG

Upstream 100 bases:

>100_bases
GCACCGGACACATCGATTATGTCACCGGCGACCTCGCCAGTTTCCTGAGCACGGCGGTGTCGAGCCTGACCGTAAAAGAA
TAAGACCGAAGAGAGATGCC

Downstream 100 bases:

>100_bases
AGCGCCGCCTCCTCAGACATGATACAGCCCCGGCGTGCGCCGCCGGTGCATGTATTTTCCAGATGGAGGCTTTGATGGCC
GACGAAATCAACGGCACTGA

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTDALARVIDAAWEGRDLLSTSTTGEVRDAVDAAISLLDSGEARVASKEADGSWTVHQWLKKAVLLSFRLNANGVMGGSP
AGGNWWDKVPSKFEGWGEKEFQEAGFRAVPPAAVRRGAFVAKNAVLMPSYVNIGAYVGEGTMIDTWASVGSCAQVGANCH
ISAGTGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVVVGEGSVLAMGVFITQSTKIVYRSTGEIIYGKVPPYSVVVPGT
LPDPKGGPSLACAVIVKTVDAQTRSKTGVNELLRD

Sequences:

>Translated_275_residues
MTDALARVIDAAWEGRDLLSTSTTGEVRDAVDAAISLLDSGEARVASKEADGSWTVHQWLKKAVLLSFRLNANGVMGGSP
AGGNWWDKVPSKFEGWGEKEFQEAGFRAVPPAAVRRGAFVAKNAVLMPSYVNIGAYVGEGTMIDTWASVGSCAQVGANCH
ISAGTGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVVVGEGSVLAMGVFITQSTKIVYRSTGEIIYGKVPPYSVVVPGT
LPDPKGGPSLACAVIVKTVDAQTRSKTGVNELLRD
>Mature_274_residues
TDALARVIDAAWEGRDLLSTSTTGEVRDAVDAAISLLDSGEARVASKEADGSWTVHQWLKKAVLLSFRLNANGVMGGSPA
GGNWWDKVPSKFEGWGEKEFQEAGFRAVPPAAVRRGAFVAKNAVLMPSYVNIGAYVGEGTMIDTWASVGSCAQVGANCHI
SAGTGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVVVGEGSVLAMGVFITQSTKIVYRSTGEIIYGKVPPYSVVVPGTL
PDPKGGPSLACAVIVKTVDAQTRSKTGVNELLRD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786362, Length=271, Percent_Identity=65.6826568265683, Blast_Score=332, Evalue=2e-92,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005664
- InterPro:   IPR023180
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.117 [H]

Molecular weight: Translated: 28768; Mature: 28637

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDALARVIDAAWEGRDLLSTSTTGEVRDAVDAAISLLDSGEARVASKEADGSWTVHQWL
CCHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHH
KKAVLLSFRLNANGVMGGSPAGGNWWDKVPSKFEGWGEKEFQEAGFRAVPPAAVRRGAFV
HHHHHEEEEECCCCCCCCCCCCCCHHHHCCHHHCCCCHHHHHHCCCCCCCHHHHHCCCCE
AKNAVLMPSYVNIGAYVGEGTMIDTWASVGSCAQVGANCHISAGTGIGGVLEPLQANPTI
ECCEEECCCHHCCEEEECCCCEEEHHHHHCHHHHHCCCEEEECCCCCCHHHCCCCCCCCE
IEDNCFIGARSEVVEGVVVGEGSVLAMGVFITQSTKIVYRSTGEIIYGKVPPYSVVVPGT
EECCCEECCHHHHHCEEEECCCCEEEEEEEEECCCEEEEEECCCEEECCCCCCEEEECCC
LPDPKGGPSLACAVIVKTVDAQTRSKTGVNELLRD
CCCCCCCCCCEEEEHHHHHCCHHHCCCCHHHHHCC
>Mature Secondary Structure 
TDALARVIDAAWEGRDLLSTSTTGEVRDAVDAAISLLDSGEARVASKEADGSWTVHQWL
CHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHH
KKAVLLSFRLNANGVMGGSPAGGNWWDKVPSKFEGWGEKEFQEAGFRAVPPAAVRRGAFV
HHHHHEEEEECCCCCCCCCCCCCCHHHHCCHHHCCCCHHHHHHCCCCCCCHHHHHCCCCE
AKNAVLMPSYVNIGAYVGEGTMIDTWASVGSCAQVGANCHISAGTGIGGVLEPLQANPTI
ECCEEECCCHHCCEEEECCCCEEEHHHHHCHHHHHCCCEEEECCCCCCHHHCCCCCCCCE
IEDNCFIGARSEVVEGVVVGEGSVLAMGVFITQSTKIVYRSTGEIIYGKVPPYSVVVPGT
EECCCEECCHHHHHCEEEECCCCEEEEEEEEECCCEEEEEECCCEEECCCCCCEEEECCC
LPDPKGGPSLACAVIVKTVDAQTRSKTGVNELLRD
CCCCCCCCCCEEEEHHHHHCCHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA