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The map label for this gene is azlB [H]

Identifier: 114799504

GI number: 114799504

Start: 3244228

End: 3244884

Strand: Reverse

Name: azlB [H]

Synonym: HNE_3069

Alternate gene names: 114799504

Gene position: 3244884-3244228 (Counterclockwise)

Preceding gene: 114797671

Following gene: 114798211

Centisome position: 87.58

GC content: 52.21

Gene sequence:

>657_bases
TTGTCGTCCAGCGTAACTTCACGATGTTTCATGGCAGACTCGCCCTCCGGGTGTCTGCGGCATATTATCATGAAAATCGA
ACGAAATAGCTTGCCTTTCTTGCAAGAAATTTGCTATTTCCGGGTATATTCTTCTAATTATCGAGGGGTTCCCGGTAAAT
TGTCCCAAGAGCTTGATACCATTGATGCCCGCATCCTGGACCTGATTCAGCATGATGCGAGCCTGTCAGTTGCAGAAATT
GCAGAACGGGTGGGACTTTCTTCTTCGCCCTGCTGGCGGCGTATCAAGCGGATGGAAGAGGCCGGTTTCATTCTCGGGCG
GGTGACGCTGATCAACAATCATGCGCTGGGGCTGAACTTCGAGGTGATTGCGAGCGTCAAACTTGCCCTACCGAGCCGGG
AAAATCTTGAGGCTTTTGAAGCACTTGTGCAGAATTGGCCGGAAGTAGTGGAATGTATGACAGTGACCGGCGCGGTGGAT
TACTCTATGCATATCGTGACGACAGACATGCATGCCTATGACAACTTCCTTCGAGACAAACTCCTTGGTTCCAAACTGGT
TTCTGACGTTCAGTCGCGGATTGTCATCCGCGTTGCGAAGCGGACCACGGCGCTGCCGCTCGGTCTTGTGCGCCAGACGA
CCAAGTCCAGCGACTAG

Upstream 100 bases:

>100_bases
GTTGTGGCCTGCGGCAAGGTCCAGGCGCTTGCGATCAAGGGGTAGGCGGACAAGGGCCTGGATGCCCGTCATATAGGCCT
TGCCCTCGACAAGTTCGTAT

Downstream 100 bases:

>100_bases
GCGCCTGCCCGCGTCGAAGGCCGTTATTTTCCTGATTTTGGCAGCCGTTTTCGTGTCAGGCCCGGTCACGGCCGAGACAA
ACTTGGACAAAACGGGACAA

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MSSSVTSRCFMADSPSGCLRHIIMKIERNSLPFLQEICYFRVYSSNYRGVPGKLSQELDTIDARILDLIQHDASLSVAEI
AERVGLSSSPCWRRIKRMEEAGFILGRVTLINNHALGLNFEVIASVKLALPSRENLEAFEALVQNWPEVVECMTVTGAVD
YSMHIVTTDMHAYDNFLRDKLLGSKLVSDVQSRIVIRVAKRTTALPLGLVRQTTKSSD

Sequences:

>Translated_218_residues
MSSSVTSRCFMADSPSGCLRHIIMKIERNSLPFLQEICYFRVYSSNYRGVPGKLSQELDTIDARILDLIQHDASLSVAEI
AERVGLSSSPCWRRIKRMEEAGFILGRVTLINNHALGLNFEVIASVKLALPSRENLEAFEALVQNWPEVVECMTVTGAVD
YSMHIVTTDMHAYDNFLRDKLLGSKLVSDVQSRIVIRVAKRTTALPLGLVRQTTKSSD
>Mature_217_residues
SSSVTSRCFMADSPSGCLRHIIMKIERNSLPFLQEICYFRVYSSNYRGVPGKLSQELDTIDARILDLIQHDASLSVAEIA
ERVGLSSSPCWRRIKRMEEAGFILGRVTLINNHALGLNFEVIASVKLALPSRENLEAFEALVQNWPEVVECMTVTGAVDY
SMHIVTTDMHAYDNFLRDKLLGSKLVSDVQSRIVIRVAKRTTALPLGLVRQTTKSSD

Specific function: Transcriptional repressor of the azlBCD operon involved in branched-chain amino acid transport [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=35.3333333333333, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1787116, Length=155, Percent_Identity=36.1290322580645, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 24392; Mature: 24260

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSVTSRCFMADSPSGCLRHIIMKIERNSLPFLQEICYFRVYSSNYRGVPGKLSQELDT
CCCCCCCCEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
IDARILDLIQHDASLSVAEIAERVGLSSSPCWRRIKRMEEAGFILGRVTLINNHALGLNF
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCCH
EVIASVKLALPSRENLEAFEALVQNWPEVVECMTVTGAVDYSMHIVTTDMHAYDNFLRDK
HHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHH
LLGSKLVSDVQSRIVIRVAKRTTALPLGLVRQTTKSSD
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
>Mature Secondary Structure 
SSSVTSRCFMADSPSGCLRHIIMKIERNSLPFLQEICYFRVYSSNYRGVPGKLSQELDT
CCCCCCCEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
IDARILDLIQHDASLSVAEIAERVGLSSSPCWRRIKRMEEAGFILGRVTLINNHALGLNF
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCCH
EVIASVKLALPSRENLEAFEALVQNWPEVVECMTVTGAVDYSMHIVTTDMHAYDNFLRDK
HHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHH
LLGSKLVSDVQSRIVIRVAKRTTALPLGLVRQTTKSSD
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9287000; 9308178; 9384377 [H]