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The map label for this gene is arsC [H]

Identifier: 114799478

GI number: 114799478

Start: 1005770

End: 1006189

Strand: Reverse

Name: arsC [H]

Synonym: HNE_0991

Alternate gene names: 114799478

Gene position: 1006189-1005770 (Counterclockwise)

Preceding gene: 114797435

Following gene: 114799094

Centisome position: 27.16

GC content: 65.71

Gene sequence:

>420_bases
ATGATCGTCATCCACCACAATCCGGACTGCGGCACCTCCCGCAACGTCCTCGCCATCATCAAGGCCAGCGGCGCCGAGCC
GGTCGTAATCGACTATCTCAAGGAAGGCTGGACCCGGCCCCAGCTCCTCGGCCTCTTCGCCGCAGCCGGCCTCACGCCCC
GCGCCGCCCTGCGCGAAAGCAAATCCCCCGCCAAGGAGCTTGGCCTGCTGGAGCCCGGCATCAGTGATGAGGCGATCCTC
GCCGCCATGCTGGAACACCCCATCCTCGTCAACCGCCCCCTCGTCTGCTCCCCCAAGGGCGTGCGCCTCTGCCGCCCCAG
CGAAGCGGTGCTCGATCTTCTCGAATCCCTGCCGCCCGGCCCTCTTTACAAGGAAGATGGCGAGATGATCATCGACGAGA
AAGGACAGCGCATTGGCTGA

Upstream 100 bases:

>100_bases
GTCGGCGTCCTCGTGGAAGTCCCCGTCATGCTCACCCTCGTCGCCTTCGCCAACCGCACACGCGATGCCTTCCCGGTTGA
AGACTGAAAGGATCAGAAAG

Downstream 100 bases:

>100_bases
CCCCGAAACCACCCTGCCCGCGCTCGACGAAGCCAGCTTCCACCCGATAGACCGCGACGCGCTCCTCACGCCCCCGCCAA
AAACCCATCCCCCGCGCATA

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MIVIHHNPDCGTSRNVLAIIKASGAEPVVIDYLKEGWTRPQLLGLFAAAGLTPRAALRESKSPAKELGLLEPGISDEAIL
AAMLEHPILVNRPLVCSPKGVRLCRPSEAVLDLLESLPPGPLYKEDGEMIIDEKGQRIG

Sequences:

>Translated_139_residues
MIVIHHNPDCGTSRNVLAIIKASGAEPVVIDYLKEGWTRPQLLGLFAAAGLTPRAALRESKSPAKELGLLEPGISDEAIL
AAMLEHPILVNRPLVCSPKGVRLCRPSEAVLDLLESLPPGPLYKEDGEMIIDEKGQRIG
>Mature_139_residues
MIVIHHNPDCGTSRNVLAIIKASGAEPVVIDYLKEGWTRPQLLGLFAAAGLTPRAALRESKSPAKELGLLEPGISDEAIL
AAMLEHPILVNRPLVCSPKGVRLCRPSEAVLDLLESLPPGPLYKEDGEMIIDEKGQRIG

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=137, Percent_Identity=50.3649635036496, Blast_Score=146, Evalue=5e-37,
Organism=Escherichia coli, GI1788841, Length=114, Percent_Identity=35.0877192982456, Blast_Score=77, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 14950; Mature: 14950

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVIHHNPDCGTSRNVLAIIKASGAEPVVIDYLKEGWTRPQLLGLFAAAGLTPRAALRES
CEEEECCCCCCCCCCEEEEEECCCCCCEEHHHHHCCCCCHHHHHHHHHCCCCHHHHHHCC
KSPAKELGLLEPGISDEAILAAMLEHPILVNRPLVCSPKGVRLCRPSEAVLDLLESLPPG
CCCHHHCCCCCCCCCHHHHHHHHHHCCEECCCCEEECCCCCEEECCCHHHHHHHHHCCCC
PLYKEDGEMIIDEKGQRIG
CCCCCCCCEEECCCCCCCC
>Mature Secondary Structure
MIVIHHNPDCGTSRNVLAIIKASGAEPVVIDYLKEGWTRPQLLGLFAAAGLTPRAALRES
CEEEECCCCCCCCCCEEEEEECCCCCCEEHHHHHCCCCCHHHHHHHHHCCCCHHHHHHCC
KSPAKELGLLEPGISDEAILAAMLEHPILVNRPLVCSPKGVRLCRPSEAVLDLLESLPPG
CCCHHHCCCCCCCCCHHHHHHHHHHCCEECCCCEEECCCCCEEECCCHHHHHHHHHCCCC
PLYKEDGEMIIDEKGQRIG
CCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006011 [H]