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The map label for this gene is sucC

Identifier: 114799396

GI number: 114799396

Start: 304074

End: 305267

Strand: Direct

Name: sucC

Synonym: HNE_0310

Alternate gene names: 114799396

Gene position: 304074-305267 (Clockwise)

Preceding gene: 114798591

Following gene: 114798328

Centisome position: 8.21

GC content: 59.63

Gene sequence:

>1194_bases
ATGAACATCCATGAATATCAGGCCAAGGCGCTGCTCAAATCCTTCGGGGCGCCTGTGGCAGAAGGCGTGCCTGTGCTCTC
GCTCGCCGATGTGCAGAAGGCAATCGACACCCTCCCAGGCCCGCTCTGGGTCGTGAAAAGCCAGATCCACGCAGGTGGCC
GCGGCAAGGGCAAATTCATCGAAAAAGAAGCCGGTGAAAAAGGCGGCGTTCGCCTCGCCTTCAACAAGGAAGACGTGAAA
AAGCACGCTGAAGCGATGCTGGGCAACCACCTCGTCACCGCGCAGACCTCTGCCGCCGGCAAACAGGTCAACCGCCTCTA
CATCGAAGACGGCGCCGACATCGAGAAAGAACTCTACCTCTCGATCCTCGTCGACCGCGCCACCTCGAACGTGGCCTTCG
TGGTCTCCACCGAAGGCGGCATGGACATCGAAGCGGTCGCCCATGACACGCCCGAGAAGATCCTCACCGTTCAGATCGAC
CCGATGGCCGGCGTCACGCCCGCTGATGCGGCCAAGATCAACTCGGCCCTGAACCTTTCAGGTTCGGCCGCTGAAGACGG
TCTCAAGCTCTACCCGATCCTCTACAAAGCCTTTGTCGAGAAAGACATGGCGATGCTGGAAGTGAACCCGTTGATCGTGA
TGAAGGACGGCCATCTGCGCGTCCTCGACGCGAAAGTGTCGTTCGACGGCAACGCGCTGTTCCGCCACCCTGACGTCGCC
GCCCTCAAGGACGAGACCGAACAGGACGCCAAGGAACTCGAAGCGGCTGAATGGGACCTTGCTTACATCGCCCTCGACGG
CACCATCGGCTGCATGGTCAACGGCGCAGGCCTTGCCATGGCAACCATGGACATCATCAAGCTCTATGGCGAAGAGCCAG
CCAACTTCTGTGACGTTGGCGGCGGCGCCGGCAAGGAGAAGGTGGCAGCTGCCTTCAAGATCATCATGAAGGACCCTAAC
GTGAAGGGTATCCTCGTGAACATCTTCGGCGGCATCATGAAGTGCGATGTCATCGCCGAAGGCGTGATCGCAGCCGTGAA
AGAAACCAATCTTGCCGTTCCGCTCGTTGTCCGCCTCGAAGGCACCAACGTCGACCTCGGCAAGAAGATCATCCGCGAGA
GCGGCCTGAACGTCATTCCGGCCGACGATCTCGACGATGCAGCCCAGAAAATTGTTAAAGCGGTGCGGGGATAG

Upstream 100 bases:

>100_bases
TCAGGCGTGTATATAGCGGCCCCGTCAACGAGGAACGGAAACGGCACCGGCACCGGCAGGCATGCTGGCGGGCTGTAAGG
CCGGACAGGGAAACCACTCC

Downstream 100 bases:

>100_bases
TTCCATGTCCATTCTGATCGACAAGAACACGAAAGTCCTGACGCAAGGCATGACCGGTAACACCGGCTCGTTCCACACCA
ATCAGGCGCTGGCTTATTAC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNIHEYQAKALLKSFGAPVAEGVPVLSLADVQKAIDTLPGPLWVVKSQIHAGGRGKGKFIEKEAGEKGGVRLAFNKEDVK
KHAEAMLGNHLVTAQTSAAGKQVNRLYIEDGADIEKELYLSILVDRATSNVAFVVSTEGGMDIEAVAHDTPEKILTVQID
PMAGVTPADAAKINSALNLSGSAAEDGLKLYPILYKAFVEKDMAMLEVNPLIVMKDGHLRVLDAKVSFDGNALFRHPDVA
ALKDETEQDAKELEAAEWDLAYIALDGTIGCMVNGAGLAMATMDIIKLYGEEPANFCDVGGGAGKEKVAAAFKIIMKDPN
VKGILVNIFGGIMKCDVIAEGVIAAVKETNLAVPLVVRLEGTNVDLGKKIIRESGLNVIPADDLDDAAQKIVKAVRG

Sequences:

>Translated_397_residues
MNIHEYQAKALLKSFGAPVAEGVPVLSLADVQKAIDTLPGPLWVVKSQIHAGGRGKGKFIEKEAGEKGGVRLAFNKEDVK
KHAEAMLGNHLVTAQTSAAGKQVNRLYIEDGADIEKELYLSILVDRATSNVAFVVSTEGGMDIEAVAHDTPEKILTVQID
PMAGVTPADAAKINSALNLSGSAAEDGLKLYPILYKAFVEKDMAMLEVNPLIVMKDGHLRVLDAKVSFDGNALFRHPDVA
ALKDETEQDAKELEAAEWDLAYIALDGTIGCMVNGAGLAMATMDIIKLYGEEPANFCDVGGGAGKEKVAAAFKIIMKDPN
VKGILVNIFGGIMKCDVIAEGVIAAVKETNLAVPLVVRLEGTNVDLGKKIIRESGLNVIPADDLDDAAQKIVKAVRG
>Mature_397_residues
MNIHEYQAKALLKSFGAPVAEGVPVLSLADVQKAIDTLPGPLWVVKSQIHAGGRGKGKFIEKEAGEKGGVRLAFNKEDVK
KHAEAMLGNHLVTAQTSAAGKQVNRLYIEDGADIEKELYLSILVDRATSNVAFVVSTEGGMDIEAVAHDTPEKILTVQID
PMAGVTPADAAKINSALNLSGSAAEDGLKLYPILYKAFVEKDMAMLEVNPLIVMKDGHLRVLDAKVSFDGNALFRHPDVA
ALKDETEQDAKELEAAEWDLAYIALDGTIGCMVNGAGLAMATMDIIKLYGEEPANFCDVGGGAGKEKVAAAFKIIMKDPN
VKGILVNIFGGIMKCDVIAEGVIAAVKETNLAVPLVVRLEGTNVDLGKKIIRESGLNVIPADDLDDAAQKIVKAVRG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=397, Percent_Identity=42.5692695214106, Blast_Score=315, Evalue=6e-86,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=43.7823834196891, Blast_Score=303, Evalue=3e-82,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=43.646408839779, Blast_Score=284, Evalue=1e-76,
Organism=Escherichia coli, GI1786948, Length=397, Percent_Identity=50.1259445843829, Blast_Score=391, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=43.2911392405063, Blast_Score=325, Evalue=3e-89,
Organism=Caenorhabditis elegans, GI17567829, Length=395, Percent_Identity=42.7848101265823, Blast_Score=307, Evalue=8e-84,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=41.1616161616162, Blast_Score=311, Evalue=9e-86,
Organism=Drosophila melanogaster, GI21356231, Length=401, Percent_Identity=47.3815461346633, Blast_Score=337, Evalue=6e-93,
Organism=Drosophila melanogaster, GI161078106, Length=406, Percent_Identity=45.8128078817734, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24645208, Length=406, Percent_Identity=45.8128078817734, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI281361397, Length=407, Percent_Identity=45.945945945946, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI281361395, Length=407, Percent_Identity=45.945945945946, Blast_Score=329, Evalue=2e-90,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_HYPNA (Q0C5F3)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_759040.1
- ProteinModelPortal:   Q0C5F3
- SMR:   Q0C5F3
- STRING:   Q0C5F3
- GeneID:   4288518
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_0310
- NMPDR:   fig|228405.5.peg.305
- TIGR:   HNE_0310
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   NPLIVMK
- PhylomeDB:   Q0C5F3
- BioCyc:   HNEP81032:HNE_0310-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42135; Mature: 42135

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKALLKSFGAPVAEGVPVLSLADVQKAIDTLPGPLWVVKSQIHAGGRGKGKFI
CCCHHHHHHHHHHHHCCCHHCCCCEEEHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCCCC
EKEAGEKGGVRLAFNKEDVKKHAEAMLGNHLVTAQTSAAGKQVNRLYIEDGADIEKELYL
HHCCCCCCCEEEEECHHHHHHHHHHHHCCCEEEEECHHCCCCEEEEEEECCCCHHHHHHH
SILVDRATSNVAFVVSTEGGMDIEAVAHDTPEKILTVQIDPMAGVTPADAAKINSALNLS
HHEEECCCCCEEEEEECCCCCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHCHHHCCC
GSAAEDGLKLYPILYKAFVEKDMAMLEVNPLIVMKDGHLRVLDAKVSFDGNALFRHPDVA
CCCCCCCCCHHHHHHHHHHHCCCEEEEECCEEEEECCCEEEEEEEEECCCCEEEECCCCH
ALKDETEQDAKELEAAEWDLAYIALDGTIGCMVNGAGLAMATMDIIKLYGEEPANFCDVG
HHCCCHHHHHHHHHHCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEECCC
GGAGKEKVAAAFKIIMKDPNVKGILVNIFGGIMKCDVIAEGVIAAVKETNLAVPLVVRLE
CCCCHHHHHHHHHHEEECCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEE
GTNVDLGKKIIRESGLNVIPADDLDDAAQKIVKAVRG
CCCCHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKALLKSFGAPVAEGVPVLSLADVQKAIDTLPGPLWVVKSQIHAGGRGKGKFI
CCCHHHHHHHHHHHHCCCHHCCCCEEEHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCCCC
EKEAGEKGGVRLAFNKEDVKKHAEAMLGNHLVTAQTSAAGKQVNRLYIEDGADIEKELYL
HHCCCCCCCEEEEECHHHHHHHHHHHHCCCEEEEECHHCCCCEEEEEEECCCCHHHHHHH
SILVDRATSNVAFVVSTEGGMDIEAVAHDTPEKILTVQIDPMAGVTPADAAKINSALNLS
HHEEECCCCCEEEEEECCCCCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHCHHHCCC
GSAAEDGLKLYPILYKAFVEKDMAMLEVNPLIVMKDGHLRVLDAKVSFDGNALFRHPDVA
CCCCCCCCCHHHHHHHHHHHCCCEEEEECCEEEEECCCEEEEEEEEECCCCEEEECCCCH
ALKDETEQDAKELEAAEWDLAYIALDGTIGCMVNGAGLAMATMDIIKLYGEEPANFCDVG
HHCCCHHHHHHHHHHCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEECCC
GGAGKEKVAAAFKIIMKDPNVKGILVNIFGGIMKCDVIAEGVIAAVKETNLAVPLVVRLE
CCCCHHHHHHHHHHEEECCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEE
GTNVDLGKKIIRESGLNVIPADDLDDAAQKIVKAVRG
CCCCHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA