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The map label for this gene is guaA [H]

Identifier: 114799238

GI number: 114799238

Start: 3408015

End: 3408746

Strand: Reverse

Name: guaA [H]

Synonym: HNE_3240

Alternate gene names: 114799238

Gene position: 3408746-3408015 (Counterclockwise)

Preceding gene: 114799785

Following gene: 114798536

Centisome position: 92.0

GC content: 65.16

Gene sequence:

>732_bases
GTGAAGCTGACAATTATTGAAACGGGCCTCGCGCCCGCCGCGATCCGCGACCGGTTTCCGAGCTATCCGGAGATGTTTGC
GCAGATGTTTGCCGGGGTGGACGCCGGGATCGTGTGCGAGACGGTGTCGCTGGTGAAGGGGGCGGCGTTGCCTGACCCGG
CGCGCCTTGAGGCTGTGCTCTACACAGGCTCGCCCGCAGGGGTTTATGATGATGAGCCGTGGATGGCGCCGCTTATGGAT
TTCATCCGGGCAGGCGCGCAGGCGAAGTGCCCGCAGCTGGGCATCTGCTTCGGGCACCAGGTGATGGCGCAGGCGCTGGG
CGGCAACGTGGTCAAGTCTGACAAGGGCTGGGGCGTGGGCGCGCATACGTATGAGATCGCGGCCCTGCCGGGCTGGCGAG
GCGGCGCGGCGCCCGCGCAGATGCGCGTGGGTGTGAGCCATCAGGATCAGGTGGTCGCCGTGCCACCGGGCGCGGATGTG
ATTGCGCATTCGGATTTTACCGAGTTTGCCGGACTTTCCTATGCGGGCTTCCCGGCGATCAGTTTTCAATGCCACCCTGA
GTTTGAGGCGGATTTTCTCGCCGCGCTGTATACGGCGCGCCGGGGACAGTCGCTGAGCGAAGATCTGGCCGATGCGGCGG
TCGCTTCCCTGCAGGAAGAAAACGACCGCCGGTTTCTGGCGCAGTGGCTTGCCAGCTTCCTTAGGGAAACGGCAGGCCCG
GCGAAGGCTTAG

Upstream 100 bases:

>100_bases
CAGCAGGCGGTCTCTATGCGGAGCTTTGGGCGCGCCAGTCCGGCGGGTTCCTGATCGAGCCTGAGCCGATTGAGAGAGAC
CTCGCCACGGAGCCGGCAGA

Downstream 100 bases:

>100_bases
CCGCCGAAGCGATAGCGCGCGCCGACGCTGAGGACGGTTTGCGTGTTCTCGATGTTCAGCGTGCCGGGGAAGAGTTGGTT
GCTGAGTTCCACGTCATCTG

Product: class I glutamine amidotransferase domain-containing protein

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKLTIIETGLAPAAIRDRFPSYPEMFAQMFAGVDAGIVCETVSLVKGAALPDPARLEAVLYTGSPAGVYDDEPWMAPLMD
FIRAGAQAKCPQLGICFGHQVMAQALGGNVVKSDKGWGVGAHTYEIAALPGWRGGAAPAQMRVGVSHQDQVVAVPPGADV
IAHSDFTEFAGLSYAGFPAISFQCHPEFEADFLAALYTARRGQSLSEDLADAAVASLQEENDRRFLAQWLASFLRETAGP
AKA

Sequences:

>Translated_243_residues
MKLTIIETGLAPAAIRDRFPSYPEMFAQMFAGVDAGIVCETVSLVKGAALPDPARLEAVLYTGSPAGVYDDEPWMAPLMD
FIRAGAQAKCPQLGICFGHQVMAQALGGNVVKSDKGWGVGAHTYEIAALPGWRGGAAPAQMRVGVSHQDQVVAVPPGADV
IAHSDFTEFAGLSYAGFPAISFQCHPEFEADFLAALYTARRGQSLSEDLADAAVASLQEENDRRFLAQWLASFLRETAGP
AKA
>Mature_243_residues
MKLTIIETGLAPAAIRDRFPSYPEMFAQMFAGVDAGIVCETVSLVKGAALPDPARLEAVLYTGSPAGVYDDEPWMAPLMD
FIRAGAQAKCPQLGICFGHQVMAQALGGNVVKSDKGWGVGAHTYEIAALPGWRGGAAPAQMRVGVSHQDQVVAVPPGADV
IAHSDFTEFAGLSYAGFPAISFQCHPEFEADFLAALYTARRGQSLSEDLADAAVASLQEENDRRFLAQWLASFLRETAGP
AKA

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GMP-binding domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323155, Length=154, Percent_Identity=31.8181818181818, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR004739
- InterPro:   IPR022955
- InterPro:   IPR022310
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00117 GATase; PF00958 GMP_synt_C; PF02540 NAD_synthase [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 25773; Mature: 25773

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTIIETGLAPAAIRDRFPSYPEMFAQMFAGVDAGIVCETVSLVKGAALPDPARLEAVL
CEEEEEECCCCCHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHEEEEE
YTGSPAGVYDDEPWMAPLMDFIRAGAQAKCPQLGICFGHQVMAQALGGNVVKSDKGWGVG
EECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCC
AHTYEIAALPGWRGGAAPAQMRVGVSHQDQVVAVPPGADVIAHSDFTEFAGLSYAGFPAI
CCEEEEEECCCCCCCCCCCCEEECCCCCCCEEEECCCCCEEECCCHHHHHCCCCCCCCEE
SFQCHPEFEADFLAALYTARRGQSLSEDLADAAVASLQEENDRRFLAQWLASFLRETAGP
EEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AKA
CCC
>Mature Secondary Structure
MKLTIIETGLAPAAIRDRFPSYPEMFAQMFAGVDAGIVCETVSLVKGAALPDPARLEAVL
CEEEEEECCCCCHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHEEEEE
YTGSPAGVYDDEPWMAPLMDFIRAGAQAKCPQLGICFGHQVMAQALGGNVVKSDKGWGVG
EECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCC
AHTYEIAALPGWRGGAAPAQMRVGVSHQDQVVAVPPGADVIAHSDFTEFAGLSYAGFPAI
CCEEEEEECCCCCCCCCCCCEEECCCCCCCEEEECCCCCEEECCCHHHHHCCCCCCCCEE
SFQCHPEFEADFLAALYTARRGQSLSEDLADAAVASLQEENDRRFLAQWLASFLRETAGP
EEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AKA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA