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The map label for this gene is cat2 [H]

Identifier: 114798989

GI number: 114798989

Start: 2419779

End: 2421032

Strand: Direct

Name: cat2 [H]

Synonym: HNE_2321

Alternate gene names: 114798989

Gene position: 2419779-2421032 (Clockwise)

Preceding gene: 114798793

Following gene: 114799189

Centisome position: 65.31

GC content: 67.15

Gene sequence:

>1254_bases
TTGCCCTATCCCAGCCTCGCCGAAGCCTTCGAGCAGTTCCGCCACCGTCTGCCGGCGCAGGCCCGCCTCTTCATCGGCGG
CGCCAGTGGCGAGCCGCTCGGCCTCGCCCGTCTCTTCAAGGCAGAACCGGACCTCAGCAGCGGCCTCACCTTCCTCGGCG
CCTGGATCGCGGGCATCAACATCACGGACTGGGCCGGCTTCCATAACAATGCCTACGCCGAAACCATCTTCCTGCCCCCT
GCCCAGCGCCCTTCCTATGATGCCGGCCGCACGCGCTTCCTGCCCCTGTCCTACAGCCAGGCCTGGCAGTGGATGGCCAC
CACGCCGCTCCACGGCGCCGTCGTCCTCGTCTCCCCGCCGGACGGGGACGGCAACGTCTCCCTCGGCGTCAGCCCGGATT
ATTCCCCCCTGATCTTCCAGCGCAGCGATGTGCCCGTCCTCGGCATCATCTGCCCCCACATGCCCGCGCCCCCGAATGCG
CCAAAAATCCCGCTATCGAAATTTGCTCAGCTGGCGGAGGATGATCACCCCCTCCTCGTGCTCCCCGGTGGCCCGCTCCC
GCCCGCCTTCGGAACTATCGCCAGCCATATCGCAAACCTGATTGACGCCGGCGACGCGCTGCAGTTCGGTGTCGGCAATG
TGCAGCAGGCCATCCTCACCGCCCTCAAGGGCCGGCGCGGCCTGCGCATCTATTCGGGCATGGTGTCAGATCCCATCCTC
GGCATGATGGACGACGACCCCACCCTGCGCGTCGATACCGGCGTCGCCGTCGGCACGCCCGCCCTCTATGCCCGCATGGC
AACGGCGCAGAACGTCCACTTCCACCCCGTCTCGAAAACCCATTTCGCCAGCGCGCTCGCCGCCGTCCCGCGCCTGCGCG
CTATCAATTCGGTCATCGAGATCGACCTTTTCGGCCAGGCCAACGCCGAATTCATCGGCGGGCGCCAGGTCGCCGGGCAA
GGCGGCCTCAACGACTTCCTGCGCGGCGCCGCCCTCTCCGAAGGCGGCCTCGCCATCACCGCCCTGATGGCCACCGCCAA
AGGCGGCGAAATCAGCCGCATCGTCCCGCGCCTCCCGCCCAACGCCGTCACCGTCATGCGCACAGACATGGATGTCGTCA
TCACAGAATTCGGCACCGCGCGCCTCCGAGGCAAAAGCATGGAAGCCCGCGCCGAAGCGCTGATTGCAATTGCCGACCCA
CGCCATCGGCCGATGCTGGCGGAAGAGTGGGAAGCGATGCGTAGGCGGATTTAA

Upstream 100 bases:

>100_bases
ACTCTCTTCAGGCCTCGTCTCGAAGGCTTCCCCCTTCTAAACCCGCGCCTGCGCCGCTAACAGAAAAGCCCGCCCCCGCT
TCAGCCGCGAAAGACGCCCC

Downstream 100 bases:

>100_bases
AGGCCAGATCGCAGCACCAACCAAACCATACAACGCTCATCCTGAGTATCCGTGTTGGTCAATTGGGTTTTGGTGTCCAT
TTCCGATTTTCTCGGATGAG

Product: putative 4-hydroxybutyrate coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MPYPSLAEAFEQFRHRLPAQARLFIGGASGEPLGLARLFKAEPDLSSGLTFLGAWIAGINITDWAGFHNNAYAETIFLPP
AQRPSYDAGRTRFLPLSYSQAWQWMATTPLHGAVVLVSPPDGDGNVSLGVSPDYSPLIFQRSDVPVLGIICPHMPAPPNA
PKIPLSKFAQLAEDDHPLLVLPGGPLPPAFGTIASHIANLIDAGDALQFGVGNVQQAILTALKGRRGLRIYSGMVSDPIL
GMMDDDPTLRVDTGVAVGTPALYARMATAQNVHFHPVSKTHFASALAAVPRLRAINSVIEIDLFGQANAEFIGGRQVAGQ
GGLNDFLRGAALSEGGLAITALMATAKGGEISRIVPRLPPNAVTVMRTDMDVVITEFGTARLRGKSMEARAEALIAIADP
RHRPMLAEEWEAMRRRI

Sequences:

>Translated_417_residues
MPYPSLAEAFEQFRHRLPAQARLFIGGASGEPLGLARLFKAEPDLSSGLTFLGAWIAGINITDWAGFHNNAYAETIFLPP
AQRPSYDAGRTRFLPLSYSQAWQWMATTPLHGAVVLVSPPDGDGNVSLGVSPDYSPLIFQRSDVPVLGIICPHMPAPPNA
PKIPLSKFAQLAEDDHPLLVLPGGPLPPAFGTIASHIANLIDAGDALQFGVGNVQQAILTALKGRRGLRIYSGMVSDPIL
GMMDDDPTLRVDTGVAVGTPALYARMATAQNVHFHPVSKTHFASALAAVPRLRAINSVIEIDLFGQANAEFIGGRQVAGQ
GGLNDFLRGAALSEGGLAITALMATAKGGEISRIVPRLPPNAVTVMRTDMDVVITEFGTARLRGKSMEARAEALIAIADP
RHRPMLAEEWEAMRRRI
>Mature_416_residues
PYPSLAEAFEQFRHRLPAQARLFIGGASGEPLGLARLFKAEPDLSSGLTFLGAWIAGINITDWAGFHNNAYAETIFLPPA
QRPSYDAGRTRFLPLSYSQAWQWMATTPLHGAVVLVSPPDGDGNVSLGVSPDYSPLIFQRSDVPVLGIICPHMPAPPNAP
KIPLSKFAQLAEDDHPLLVLPGGPLPPAFGTIASHIANLIDAGDALQFGVGNVQQAILTALKGRRGLRIYSGMVSDPILG
MMDDDPTLRVDTGVAVGTPALYARMATAQNVHFHPVSKTHFASALAAVPRLRAINSVIEIDLFGQANAEFIGGRQVAGQG
GLNDFLRGAALSEGGLAITALMATAKGGEISRIVPRLPPNAVTVMRTDMDVVITEFGTARLRGKSMEARAEALIAIADPR
HRPMLAEEWEAMRRRI

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI32563853, Length=312, Percent_Identity=32.6923076923077, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17538151, Length=359, Percent_Identity=28.133704735376, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21358615, Length=316, Percent_Identity=33.5443037974684, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 44563; Mature: 44432

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYPSLAEAFEQFRHRLPAQARLFIGGASGEPLGLARLFKAEPDLSSGLTFLGAWIAGIN
CCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCC
ITDWAGFHNNAYAETIFLPPAQRPSYDAGRTRFLPLSYSQAWQWMATTPLHGAVVLVSPP
EEECCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCHHHHCCEEECCCCCCEEEEEECC
DGDGNVSLGVSPDYSPLIFQRSDVPVLGIICPHMPAPPNAPKIPLSKFAQLAEDDHPLLV
CCCCCEEECCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCEEE
LPGGPLPPAFGTIASHIANLIDAGDALQFGVGNVQQAILTALKGRRGLRIYSGMVSDPIL
ECCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHCCCCCCEEECCCCCCCCE
GMMDDDPTLRVDTGVAVGTPALYARMATAQNVHFHPVSKTHFASALAAVPRLRAINSVIE
EECCCCCCEEEECCCEECCHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHEEE
IDLFGQANAEFIGGRQVAGQGGLNDFLRGAALSEGGLAITALMATAKGGEISRIVPRLPP
EEEECCCCCEEECCEEECCCCCHHHHHHCCCCCCCCEEEEEEEHHCCCCCHHHHCCCCCC
NAVTVMRTDMDVVITEFGTARLRGKSMEARAEALIAIADPRHRPMLAEEWEAMRRRI
CCEEEEECCCEEEEECCCCHHCCCCCHHHHCEEEEEEECCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PYPSLAEAFEQFRHRLPAQARLFIGGASGEPLGLARLFKAEPDLSSGLTFLGAWIAGIN
CCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCC
ITDWAGFHNNAYAETIFLPPAQRPSYDAGRTRFLPLSYSQAWQWMATTPLHGAVVLVSPP
EEECCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCHHHHCCEEECCCCCCEEEEEECC
DGDGNVSLGVSPDYSPLIFQRSDVPVLGIICPHMPAPPNAPKIPLSKFAQLAEDDHPLLV
CCCCCEEECCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCEEE
LPGGPLPPAFGTIASHIANLIDAGDALQFGVGNVQQAILTALKGRRGLRIYSGMVSDPIL
ECCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHCCCCCCEEECCCCCCCCE
GMMDDDPTLRVDTGVAVGTPALYARMATAQNVHFHPVSKTHFASALAAVPRLRAINSVIE
EECCCCCCEEEECCCEECCHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHEEE
IDLFGQANAEFIGGRQVAGQGGLNDFLRGAALSEGGLAITALMATAKGGEISRIVPRLPP
EEEECCCCCEEECCEEECCCCCHHHHHHCCCCCCCCEEEEEEEHHCCCCCHHHHCCCCCC
NAVTVMRTDMDVVITEFGTARLRGKSMEARAEALIAIADPRHRPMLAEEWEAMRRRI
CCEEEEECCCEEEEECCCCHHCCCCCHHHHCEEEEEEECCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]