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The map label for this gene is yfmJ [H]

Identifier: 114798815

GI number: 114798815

Start: 2368931

End: 2369962

Strand: Direct

Name: yfmJ [H]

Synonym: HNE_2266

Alternate gene names: 114798815

Gene position: 2368931-2369962 (Clockwise)

Preceding gene: 114798803

Following gene: 114799351

Centisome position: 63.94

GC content: 62.6

Gene sequence:

>1032_bases
GTGAGCGGCGCGGAGACCCTGCAGCAGATCGTGCTTGCCCAATATTGCGACGGGGTCCCGAAGCCTTCAGACTTCCGGCT
GGAAACCGCGCCCCTTCCAGAGCCCAAGGACGGCCAGTTCCGCGTGGCGCATGTCTGGTGCTCAGTTGATCCTGGCACCC
GCTCACGCCTCTCAGGCGGCGACAGCTACGCCGCTGCGCTTCCACTCGGCAAACCCATCGACGGCTTCAGCGTGGGCGTC
GTTGATGCCTCCAGCAATCCTGACTGGCCGGTCGGCACGAAGGTGTTCTGTGCGGGCGGCTGGAAGACGCATTCGATCCA
GTCCGGCAAGGGCTTCATCGGCAAGGTGATGGACGTTCCGGGCGTGCCGCTCTCTGCCTGGATCGGCGTACTCGGCGTGC
CGGGGCTGACGGCGTGGTTTGGCATGAAGGACGTGGCGCGCTTCAAGGAAGGCGACGCCGTGCTTGTTACCTCCGCCGCT
GGTCCTGTAGGCGCCACAGCAGGACAGCTCGCCAAGGGCTGGGGCGCGTCAAAGGTTGTGGGCGTGGCAGGCAGCGACGA
GAAGTGCCGCTGGCTGGTCTCCGAAGCGGGCTTTGACGCAGCCATCAACTACAAGACGGCGAGCGATCTTTCCGGCGCGA
TAGCAGCCGAGTTTCCCAAGGGCGTCGATGTGCTGTTCGACAATGTGGGGAATGCGATGGTCGATACCGTGCTGCCACTG
ATGGCGCTGAACGGGCGGATATGCATTTCGGGTCAGGTGGCCGATTACAACCTGAAGCCCGAGGAAACACCCGGCATTGT
CCACACCAAACCCTTCATCACCCACCGGGTGAACATGCAGGGGCTGGTGGTGTTTGATTTTGCGCGTGGTTTCCCGGAAG
CCCTTGGTTCGATGGCGAAAATGATCGCCTCAGGCGCCCTCAAAATTCAGGAGGATCGCTTCGAGGGCATCGCGGAAATA
CCTGAAGCCTTCTGTGGACTTTTCCGGGGGGAAAATTCGGGCCGCCGGGTGGTCAAGGTCGGCGCAGAATAG

Upstream 100 bases:

>100_bases
CGGGCTTCAAGATCGTTCCGGTCTGCCCCTATGTGCGCGGCCAGTACGCCAAACACCCCGAATGGTCTGACCTGTTCACA
ACGAAGCCGGGCGAAGACCC

Downstream 100 bases:

>100_bases
CGAGGTTTAGTCCTCGTCGTCCTCGTCATCATCCTTGTTCAGGAAGCTGGAGAGGATGAGACCGGCAATCGCGGTGATGG
CGACAATCTGTTTGCCACTG

Product: zinc-binding dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSGAETLQQIVLAQYCDGVPKPSDFRLETAPLPEPKDGQFRVAHVWCSVDPGTRSRLSGGDSYAAALPLGKPIDGFSVGV
VDASSNPDWPVGTKVFCAGGWKTHSIQSGKGFIGKVMDVPGVPLSAWIGVLGVPGLTAWFGMKDVARFKEGDAVLVTSAA
GPVGATAGQLAKGWGASKVVGVAGSDEKCRWLVSEAGFDAAINYKTASDLSGAIAAEFPKGVDVLFDNVGNAMVDTVLPL
MALNGRICISGQVADYNLKPEETPGIVHTKPFITHRVNMQGLVVFDFARGFPEALGSMAKMIASGALKIQEDRFEGIAEI
PEAFCGLFRGENSGRRVVKVGAE

Sequences:

>Translated_343_residues
MSGAETLQQIVLAQYCDGVPKPSDFRLETAPLPEPKDGQFRVAHVWCSVDPGTRSRLSGGDSYAAALPLGKPIDGFSVGV
VDASSNPDWPVGTKVFCAGGWKTHSIQSGKGFIGKVMDVPGVPLSAWIGVLGVPGLTAWFGMKDVARFKEGDAVLVTSAA
GPVGATAGQLAKGWGASKVVGVAGSDEKCRWLVSEAGFDAAINYKTASDLSGAIAAEFPKGVDVLFDNVGNAMVDTVLPL
MALNGRICISGQVADYNLKPEETPGIVHTKPFITHRVNMQGLVVFDFARGFPEALGSMAKMIASGALKIQEDRFEGIAEI
PEAFCGLFRGENSGRRVVKVGAE
>Mature_342_residues
SGAETLQQIVLAQYCDGVPKPSDFRLETAPLPEPKDGQFRVAHVWCSVDPGTRSRLSGGDSYAAALPLGKPIDGFSVGVV
DASSNPDWPVGTKVFCAGGWKTHSIQSGKGFIGKVMDVPGVPLSAWIGVLGVPGLTAWFGMKDVARFKEGDAVLVTSAAG
PVGATAGQLAKGWGASKVVGVAGSDEKCRWLVSEAGFDAAINYKTASDLSGAIAAEFPKGVDVLFDNVGNAMVDTVLPLM
ALNGRICISGQVADYNLKPEETPGIVHTKPFITHRVNMQGLVVFDFARGFPEALGSMAKMIASGALKIQEDRFEGIAEIP
EAFCGLFRGENSGRRVVKVGAE

Specific function: Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds (Potential) [H]

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226059159, Length=335, Percent_Identity=37.0149253731343, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI226059133, Length=335, Percent_Identity=37.0149253731343, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI226246682, Length=337, Percent_Identity=31.4540059347181, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI226246680, Length=337, Percent_Identity=31.4540059347181, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI22748929, Length=337, Percent_Identity=31.4540059347181, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI226056130, Length=306, Percent_Identity=36.2745098039216, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI28557745, Length=220, Percent_Identity=32.7272727272727, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI194239674, Length=252, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI13236495, Length=252, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI226510941, Length=340, Percent_Identity=35.2941176470588, Blast_Score=201, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI133901710, Length=327, Percent_Identity=31.8042813455657, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI133901712, Length=327, Percent_Identity=31.8042813455657, Blast_Score=141, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6323504, Length=330, Percent_Identity=29.3939393939394, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35942; Mature: 35811

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGAETLQQIVLAQYCDGVPKPSDFRLETAPLPEPKDGQFRVAHVWCSVDPGTRSRLSGG
CCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCEEEEEEEEECCCCCCHHCCCC
DSYAAALPLGKPIDGFSVGVVDASSNPDWPVGTKVFCAGGWKTHSIQSGKGFIGKVMDVP
CCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCEECCCCCCCCCEEHHHCCC
GVPLSAWIGVLGVPGLTAWFGMKDVARFKEGDAVLVTSAAGPVGATAGQLAKGWGASKVV
CCCHHHHHHHHCCCCHHHHHCHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCCCEEE
GVAGSDEKCRWLVSEAGFDAAINYKTASDLSGAIAAEFPKGVDVLFDNVGNAMVDTVLPL
EECCCCCHHEEEEECCCCCEEEECCCHHCCCCCHHHCCCCCHHHHHHHCCHHHHHHHHHH
MALNGRICISGQVADYNLKPEETPGIVHTKPFITHRVNMQGLVVFDFARGFPEALGSMAK
HHCCCEEEEECEEECCCCCCCCCCCEEECCCCEEEEECCCEEEEEEHHCCCHHHHHHHHH
MIASGALKIQEDRFEGIAEIPEAFCGLFRGENSGRRVVKVGAE
HHHHCCEEEEHHHHCCHHHHHHHHHHHHCCCCCCCEEEEECCC
>Mature Secondary Structure 
SGAETLQQIVLAQYCDGVPKPSDFRLETAPLPEPKDGQFRVAHVWCSVDPGTRSRLSGG
CHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCEEEEEEEEECCCCCCHHCCCC
DSYAAALPLGKPIDGFSVGVVDASSNPDWPVGTKVFCAGGWKTHSIQSGKGFIGKVMDVP
CCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCEECCCCCCCCCEEHHHCCC
GVPLSAWIGVLGVPGLTAWFGMKDVARFKEGDAVLVTSAAGPVGATAGQLAKGWGASKVV
CCCHHHHHHHHCCCCHHHHHCHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCCCEEE
GVAGSDEKCRWLVSEAGFDAAINYKTASDLSGAIAAEFPKGVDVLFDNVGNAMVDTVLPL
EECCCCCHHEEEEECCCCCEEEECCCHHCCCCCHHHCCCCCHHHHHHHCCHHHHHHHHHH
MALNGRICISGQVADYNLKPEETPGIVHTKPFITHRVNMQGLVVFDFARGFPEALGSMAK
HHCCCEEEEECEEECCCCCCCCCCCEEECCCCEEEEECCCEEEEEEHHCCCHHHHHHHHH
MIASGALKIQEDRFEGIAEIPEAFCGLFRGENSGRRVVKVGAE
HHHHCCEEEEHHHHCCHHHHHHHHHHHHCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]