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The map label for this gene is grp [H]

Identifier: 114798689

GI number: 114798689

Start: 170081

End: 170575

Strand: Direct

Name: grp [H]

Synonym: HNE_0182

Alternate gene names: 114798689

Gene position: 170081-170575 (Clockwise)

Preceding gene: 114800245

Following gene: 114798529

Centisome position: 4.59

GC content: 53.33

Gene sequence:

>495_bases
TTGGAAGAGTATAATTTTCGGAATAAATATCTATTTATGGAAAACATTGATGATACGGATCGATTGATCCTTCGCGCACT
GCAAGCGGACGGAAGCGCATCGCTCGAATCCATTTCGGCGGGCGCCAGCATTTCAGTGAACACCTGCTGGCGCCGGGTGA
AGCGGCTGGAAGAGGCCGGGATTGTCTCTAAGCGAGTAGCTTTGATTGATCCGGAAAAGGTTGGCTTGGCCCAAACCGTC
TTCGTTGCCATACGCACCCGAGATCATTCTGCCGCCTGGCTACAGCGCTTTTCGGCTGCAGTTAGCGCGGTCCCGGAAGT
CATAGAGTTCTATCGGATGGCGGGCGACGTGGATTACCTGCTGAAAATTCAGGTGGGTAGCGTCGCTGACTATGACCGTG
TTTACAAAGCGCTGATCGCGCGGGTCGACCTTGCCGATGTCAGCGCCACTTTTGCAATGGAGTGCCTGAAAAACACGACC
GAACTACCGCTTTAG

Upstream 100 bases:

>100_bases
AAACGGCGGGCGGCGTTATAGCGGAAGCGGGCTGAGGCATACGAGTAATGTCTCACGCCATTTACGCAGTTTCATCTTAG
AAAATTATCAAAAAGTACTA

Downstream 100 bases:

>100_bases
AAAGCAGGCGCGGGAGCGGGGAGCATAAGTTCCGGCATCAGGCAGCTGGCGAGGGGTTGGCCAGGGGTTGTTTTGGTCAG
GCCTTCGGGCTCGCGCAGAT

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MEEYNFRNKYLFMENIDDTDRLILRALQADGSASLESISAGASISVNTCWRRVKRLEEAGIVSKRVALIDPEKVGLAQTV
FVAIRTRDHSAAWLQRFSAAVSAVPEVIEFYRMAGDVDYLLKIQVGSVADYDRVYKALIARVDLADVSATFAMECLKNTT
ELPL

Sequences:

>Translated_164_residues
MEEYNFRNKYLFMENIDDTDRLILRALQADGSASLESISAGASISVNTCWRRVKRLEEAGIVSKRVALIDPEKVGLAQTV
FVAIRTRDHSAAWLQRFSAAVSAVPEVIEFYRMAGDVDYLLKIQVGSVADYDRVYKALIARVDLADVSATFAMECLKNTT
ELPL
>Mature_164_residues
MEEYNFRNKYLFMENIDDTDRLILRALQADGSASLESISAGASISVNTCWRRVKRLEEAGIVSKRVALIDPEKVGLAQTV
FVAIRTRDHSAAWLQRFSAAVSAVPEVIEFYRMAGDVDYLLKIQVGSVADYDRVYKALIARVDLADVSATFAMECLKNTT
ELPL

Specific function: Represses the secondary, H(+)-coupled glutamate uptake system (Gluemp) genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=46, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1787116, Length=150, Percent_Identity=30.6666666666667, Blast_Score=78, Evalue=2e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 18340; Mature: 18340

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEYNFRNKYLFMENIDDTDRLILRALQADGSASLESISAGASISVNTCWRRVKRLEEAG
CCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHC
IVSKRVALIDPEKVGLAQTVFVAIRTRDHSAAWLQRFSAAVSAVPEVIEFYRMAGDVDYL
HHHHHEEEECCHHHCHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LKIQVGSVADYDRVYKALIARVDLADVSATFAMECLKNTTELPL
EEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEEYNFRNKYLFMENIDDTDRLILRALQADGSASLESISAGASISVNTCWRRVKRLEEAG
CCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHC
IVSKRVALIDPEKVGLAQTVFVAIRTRDHSAAWLQRFSAAVSAVPEVIEFYRMAGDVDYL
HHHHHEEEECCHHHCHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LKIQVGSVADYDRVYKALIARVDLADVSATFAMECLKNTTELPL
EEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665494 [H]