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The map label for this gene is tqsA [H]

Identifier: 114798684

GI number: 114798684

Start: 3285977

End: 3287065

Strand: Reverse

Name: tqsA [H]

Synonym: HNE_3106

Alternate gene names: 114798684

Gene position: 3287065-3285977 (Counterclockwise)

Preceding gene: 114798945

Following gene: 114799217

Centisome position: 88.72

GC content: 60.06

Gene sequence:

>1089_bases
ATGGGCAGCGCCACCAAGTCCGGCATCTGGATTATCGCGACCGGCGTTATCATCGCGCTGCTCTATTTCGGCCGTGAAAT
CCTCGCCACTTTCGCCATGGCGGTATTCCTGTTCCTCATCATTGAGGGCTTCGGCACCGTCATCAACAATGCCTCGCGCA
CCATCCATATCGGCCCCGCCAGAATACTGGCCGTGTTGCTCGTAGTCGGCGGCTTTGTCGGTTTCATCGCGCTGATGGCA
GACGGGGTCGCGGAGTTTGGCCGCGATGGCAGCGAGTATGAGGAGAAGATCAACGCCCTGATCGCCGATGTCTATCGCCT
CGCAGGCCTGAAGGACGCGCCAACGCTGACCCAGCTGGCCTTCGATGAAGGCGGCCAGCGCTTCTTCGCCAACATTGCCA
ATTCCGTCCGCGGCCTCTCTGGCGACATTGTGCTGATCCTGATCTATGTCGCCTTCCTCTTCACCGCCCAGTCAATGTGG
ACGCAGAAGCTCGACAATATTTTCCCGGAGGCAGACCGGCGGGAAATGGTCCGCCGCATCGGCAATGATGCGCGCCTCGC
CATCGAGAAATATCTGTGGACGCAGACGGTGATCTCGGCGCTGATCACGCTGCTTTCCTACATCTCGCTTTTGGCACTGG
GCGTGCAAAATGCCCTGTTCCTGTCAGCCGTCATATTCGTGCTGAACTACATCCCGACGGTCGGCTCAATTGTCGCAGCT
CTGGTCCCGCCGCTGTTCGCCCTGGTACAGCCGGTGATCCCCGGCTGGGTGCCCGCGCTCGCACTCGACGAATCCTATGT
CTACGCTGTCATCGTGTTCGCGATTGTCAGCTTCTGGCAGTTCTCGATCGGCAATTTCATCCAGCCCCGGATGATGGGGG
ATTCGCTGAATCTCTCGGCACTTGTGGTCCTTCTGGCCCTGGCGATCTGGGGCGTGCTGTGGGGAATCCCCGGCATGTTC
CTGTCGGCGCCGCTGACGGTCCTGATGATGATCCTGTTCGCCCAGTCGCCTCATACGCGATGGATCGCCATCCTGCTTTC
GGCTGATGGAAAACCCCAGGTCCGTGCCGCTGCCGAAACCGCGGGTTGA

Upstream 100 bases:

>100_bases
ATTCCGGCAATTTGAGCAAGTCAAGGCGCGCAGGTTTCTCCCCGCTTGACGGGTGTGAGGCGGGGCCGCACTGATGGGAA
AGGGTCAATCGGAGCAATAC

Downstream 100 bases:

>100_bases
CTGTGCGGAAGACTAGTCAGCCCGCCATTGAAATGTTACATCATGAACGGGTTGAGGCTGTGGGTTAGCGATTCTGGCTT
TCCTTACTACCGAAAATTAA

Product: hypothetical protein

Products: NA

Alternate protein names: Transport of quorum-sensing signal protein [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MGSATKSGIWIIATGVIIALLYFGREILATFAMAVFLFLIIEGFGTVINNASRTIHIGPARILAVLLVVGGFVGFIALMA
DGVAEFGRDGSEYEEKINALIADVYRLAGLKDAPTLTQLAFDEGGQRFFANIANSVRGLSGDIVLILIYVAFLFTAQSMW
TQKLDNIFPEADRREMVRRIGNDARLAIEKYLWTQTVISALITLLSYISLLALGVQNALFLSAVIFVLNYIPTVGSIVAA
LVPPLFALVQPVIPGWVPALALDESYVYAVIVFAIVSFWQFSIGNFIQPRMMGDSLNLSALVVLLALAIWGVLWGIPGMF
LSAPLTVLMMILFAQSPHTRWIAILLSADGKPQVRAAAETAG

Sequences:

>Translated_362_residues
MGSATKSGIWIIATGVIIALLYFGREILATFAMAVFLFLIIEGFGTVINNASRTIHIGPARILAVLLVVGGFVGFIALMA
DGVAEFGRDGSEYEEKINALIADVYRLAGLKDAPTLTQLAFDEGGQRFFANIANSVRGLSGDIVLILIYVAFLFTAQSMW
TQKLDNIFPEADRREMVRRIGNDARLAIEKYLWTQTVISALITLLSYISLLALGVQNALFLSAVIFVLNYIPTVGSIVAA
LVPPLFALVQPVIPGWVPALALDESYVYAVIVFAIVSFWQFSIGNFIQPRMMGDSLNLSALVVLLALAIWGVLWGIPGMF
LSAPLTVLMMILFAQSPHTRWIAILLSADGKPQVRAAAETAG
>Mature_361_residues
GSATKSGIWIIATGVIIALLYFGREILATFAMAVFLFLIIEGFGTVINNASRTIHIGPARILAVLLVVGGFVGFIALMAD
GVAEFGRDGSEYEEKINALIADVYRLAGLKDAPTLTQLAFDEGGQRFFANIANSVRGLSGDIVLILIYVAFLFTAQSMWT
QKLDNIFPEADRREMVRRIGNDARLAIEKYLWTQTVISALITLLSYISLLALGVQNALFLSAVIFVLNYIPTVGSIVAAL
VPPLFALVQPVIPGWVPALALDESYVYAVIVFAIVSFWQFSIGNFIQPRMMGDSLNLSALVVLLALAIWGVLWGIPGMFL
SAPLTVLMMILFAQSPHTRWIAILLSADGKPQVRAAAETAG

Specific function: Controls the transport of the quorum-sensing signal AI-2 either by enhancing its secretion or inhibiting its uptake and consequently represses biofilm formation and motility and affects the global gene expression in biofilms [H]

COG id: COG0628

COG function: function code R; Predicted permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0118 (perM) family [H]

Homologues:

Organism=Escherichia coli, GI1787885, Length=165, Percent_Identity=38.1818181818182, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87082271, Length=174, Percent_Identity=33.9080459770115, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002549 [H]

Pfam domain/function: PF01594 UPF0118 [H]

EC number: NA

Molecular weight: Translated: 39202; Mature: 39071

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSATKSGIWIIATGVIIALLYFGREILATFAMAVFLFLIIEGFGTVINNASRTIHIGPA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHH
RILAVLLVVGGFVGFIALMADGVAEFGRDGSEYEEKINALIADVYRLAGLKDAPTLTQLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
FDEGGQRFFANIANSVRGLSGDIVLILIYVAFLFTAQSMWTQKLDNIFPEADRREMVRRI
HHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GNDARLAIEKYLWTQTVISALITLLSYISLLALGVQNALFLSAVIFVLNYIPTVGSIVAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVPPLFALVQPVIPGWVPALALDESYVYAVIVFAIVSFWQFSIGNFIQPRMMGDSLNLSA
HHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHCHHHCCCCCCHHH
LVVLLALAIWGVLWGIPGMFLSAPLTVLMMILFAQSPHTRWIAILLSADGKPQVRAAAET
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHC
AG
CC
>Mature Secondary Structure 
GSATKSGIWIIATGVIIALLYFGREILATFAMAVFLFLIIEGFGTVINNASRTIHIGPA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHH
RILAVLLVVGGFVGFIALMADGVAEFGRDGSEYEEKINALIADVYRLAGLKDAPTLTQLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
FDEGGQRFFANIANSVRGLSGDIVLILIYVAFLFTAQSMWTQKLDNIFPEADRREMVRRI
HHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GNDARLAIEKYLWTQTVISALITLLSYISLLALGVQNALFLSAVIFVLNYIPTVGSIVAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVPPLFALVQPVIPGWVPALALDESYVYAVIVFAIVSFWQFSIGNFIQPRMMGDSLNLSA
HHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHCHHHCCCCCCHHH
LVVLLALAIWGVLWGIPGMFLSAPLTVLMMILFAQSPHTRWIAILLSADGKPQVRAAAET
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHC
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]