| Definition | Hyphomonas neptunium ATCC 15444 chromosome, complete genome. |
|---|---|
| Accession | NC_008358 |
| Length | 3,705,021 |
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The map label for this gene is linX [H]
Identifier: 114798449
GI number: 114798449
Start: 3424306
End: 3425079
Strand: Reverse
Name: linX [H]
Synonym: HNE_3259
Alternate gene names: 114798449
Gene position: 3425079-3424306 (Counterclockwise)
Preceding gene: 114800220
Following gene: 114799477
Centisome position: 92.44
GC content: 62.14
Gene sequence:
>774_bases ATGGGCCGCGTTTCAGGTAAAATGGCACTCATCACGGGCGGGGCCCAGGGCCTCGGCGAAGCCACCGCCCGCATGTTCGC CCGCGAAGGCGCCAAGGTCACGGTCACCGACGTGAACGGCGCCGGCGCCGAAAAGGTCGCCGCCTCCATCAACGAGGCCC ACGGGCCCGGCACCGCCTTTGCCTTCCAGCATGACGTCACCAGCGAAGAACAGTGGAAAGACGTCGCCCAGAAAGCCCAT GACGCGATGGGCGGCCTCAACATCCTCATCAACAATGCCGGCATCGGCGGCCTCGGCTCGGTCGAGGACGAAACCTATGA GCGCTTCCGGAAAGTGCAGGCCGTGGACGTCGATTCCATCTTTCTGGGGTGCAAATATTCCATCCCCCTGATGCGCGACC ATGGCCTCGGCTCCATCGTCAACATCTCGTCCATCGCGGGCATCATCGCCAGCGCCAATTATATCTCCTACAACACGGCC AAAGCGGCGGTGCGTCACATGTCGAAATCCATCGCGCTCCACCTTGCCAAGACCGGCGGCCAGATCCGCTGTAACTCCGT CCACCCCGTATTCATCAACACGCCGATCCTTGATGGCATCAAGGAAATGTTCGGCGAGGAGAAGGGCCTGCAAAAGCTCG CCCGCCAGGTCCCGCTCGGCAAGGTGGGTGAGCCCGACGACATCGCCTATGCCGTGCTTTATCTGGCGTCGGACGAATCC AAACTCGTCACCGGCGCCGAACTGAAAGTCGATGGCGGCATCAGCGCGATGTAG
Upstream 100 bases:
>100_bases GGATTGTTGGAAATTTGATCGATCGGGCAAAAGCCGGGCTTGGCGAGCGGGGAAGCGGGCTGCTAGGGCTGGGATCAGGA AAAAATCAGGAGGAAATTCA
Downstream 100 bases:
>100_bases GCGGTAGACAGCGCTGGCCAAATCACTCCAGAAATAACCGTCACCTATTGGCGCATGGCTCGTTTCAGCAAGGTCTGCAT GAAGAAATCGGGTTTTTGCC
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 2,5-DDOL dehydrogenase [H]
Number of amino acids: Translated: 257; Mature: 256
Protein sequence:
>257_residues MGRVSGKMALITGGAQGLGEATARMFAREGAKVTVTDVNGAGAEKVAASINEAHGPGTAFAFQHDVTSEEQWKDVAQKAH DAMGGLNILINNAGIGGLGSVEDETYERFRKVQAVDVDSIFLGCKYSIPLMRDHGLGSIVNISSIAGIIASANYISYNTA KAAVRHMSKSIALHLAKTGGQIRCNSVHPVFINTPILDGIKEMFGEEKGLQKLARQVPLGKVGEPDDIAYAVLYLASDES KLVTGAELKVDGGISAM
Sequences:
>Translated_257_residues MGRVSGKMALITGGAQGLGEATARMFAREGAKVTVTDVNGAGAEKVAASINEAHGPGTAFAFQHDVTSEEQWKDVAQKAH DAMGGLNILINNAGIGGLGSVEDETYERFRKVQAVDVDSIFLGCKYSIPLMRDHGLGSIVNISSIAGIIASANYISYNTA KAAVRHMSKSIALHLAKTGGQIRCNSVHPVFINTPILDGIKEMFGEEKGLQKLARQVPLGKVGEPDDIAYAVLYLASDES KLVTGAELKVDGGISAM >Mature_256_residues GRVSGKMALITGGAQGLGEATARMFAREGAKVTVTDVNGAGAEKVAASINEAHGPGTAFAFQHDVTSEEQWKDVAQKAHD AMGGLNILINNAGIGGLGSVEDETYERFRKVQAVDVDSIFLGCKYSIPLMRDHGLGSIVNISSIAGIIASANYISYNTAK AAVRHMSKSIALHLAKTGGQIRCNSVHPVFINTPILDGIKEMFGEEKGLQKLARQVPLGKVGEPDDIAYAVLYLASDESK LVTGAELKVDGGISAM
Specific function: Catalyzes the degradation of 2,5-dichloro-2,5- cyclohexadiene-1,4-diol (2,5-DDOL) into 2,5-dichlorohydroquinone (2,5-DCHQ). LinX appears not to be involved in gamma-HCH degradation pathway [H]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=30.6818181818182, Blast_Score=113, Evalue=2e-25, Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=34.6303501945525, Blast_Score=108, Evalue=5e-24, Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=30.241935483871, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=3e-23, Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=29.6442687747036, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI59889578, Length=234, Percent_Identity=30.3418803418803, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=27.8195488721804, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=30.241935483871, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=33.5294117647059, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=29.3650793650794, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=25.5905511811024, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI4758504, Length=264, Percent_Identity=30.6818181818182, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI109715829, Length=249, Percent_Identity=24.4979919678715, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI142976729, Length=247, Percent_Identity=27.5303643724696, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=30.8510638297872, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI83715985, Length=264, Percent_Identity=29.5454545454545, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI40807363, Length=197, Percent_Identity=30.4568527918782, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI310128830, Length=207, Percent_Identity=28.5024154589372, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI310115468, Length=207, Percent_Identity=28.5024154589372, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI4504505, Length=199, Percent_Identity=28.643216080402, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=29.8969072164948, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI126723750, Length=259, Percent_Identity=24.3243243243243, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI210032110, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI40254986, Length=224, Percent_Identity=27.2321428571429, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=32.5581395348837, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=35.8565737051793, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=34.2412451361868, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=32.421875, Blast_Score=108, Evalue=4e-25, Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=5e-24, Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=30.6201550387597, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=26.1904761904762, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=26.7441860465116, Blast_Score=91, Evalue=5e-20, Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=28.4, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=26.8774703557312, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI2367365, Length=260, Percent_Identity=28.0769230769231, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=24.2063492063492, Blast_Score=71, Evalue=9e-14, Organism=Escherichia coli, GI1787526, Length=252, Percent_Identity=25, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=33.59375, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI25147288, Length=255, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=7e-27, Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=32.3420074349442, Blast_Score=106, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=33.210332103321, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562906, Length=271, Percent_Identity=31.3653136531365, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17563726, Length=273, Percent_Identity=32.2344322344322, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=29.1187739463602, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17562910, Length=272, Percent_Identity=30.8823529411765, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI193204405, Length=281, Percent_Identity=30.6049822064057, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI72000259, Length=270, Percent_Identity=30.3703703703704, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=31.6205533596838, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17531453, Length=275, Percent_Identity=32.3636363636364, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=29.7619047619048, Blast_Score=99, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=31.8518518518519, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17562904, Length=274, Percent_Identity=30.6569343065693, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17560150, Length=269, Percent_Identity=30.4832713754647, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17564282, Length=201, Percent_Identity=33.8308457711443, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=29.4776119402985, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17562908, Length=275, Percent_Identity=29.8181818181818, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17560220, Length=279, Percent_Identity=31.5412186379928, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=29.9625468164794, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=31.3207547169811, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17567345, Length=195, Percent_Identity=32.8205128205128, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17538182, Length=262, Percent_Identity=29.0076335877863, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=28.1853281853282, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=30.0395256916996, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=30.3030303030303, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=30.1115241635688, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI193203115, Length=197, Percent_Identity=29.9492385786802, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17508651, Length=258, Percent_Identity=31.0077519379845, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17568967, Length=204, Percent_Identity=32.843137254902, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=27.6923076923077, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=26.953125, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17536025, Length=260, Percent_Identity=26.5384615384615, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI71982365, Length=167, Percent_Identity=27.5449101796407, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=25.4980079681275, Blast_Score=65, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=245, Percent_Identity=26.9387755102041, Blast_Score=64, Evalue=2e-11, Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=34.5098039215686, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI21357041, Length=263, Percent_Identity=33.4600760456274, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=32.156862745098, Blast_Score=114, Evalue=6e-26, Organism=Drosophila melanogaster, GI28571526, Length=263, Percent_Identity=31.9391634980989, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=30.3501945525292, Blast_Score=111, Evalue=5e-25, Organism=Drosophila melanogaster, GI24644337, Length=257, Percent_Identity=33.852140077821, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI21355319, Length=265, Percent_Identity=29.811320754717, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI17737361, Length=267, Percent_Identity=30.7116104868914, Blast_Score=95, Evalue=6e-20, Organism=Drosophila melanogaster, GI24640492, Length=203, Percent_Identity=29.064039408867, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI281364892, Length=211, Percent_Identity=27.9620853080569, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24649181, Length=193, Percent_Identity=27.979274611399, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI21355631, Length=146, Percent_Identity=29.4520547945205, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI18859837, Length=196, Percent_Identity=30.1020408163265, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24581726, Length=199, Percent_Identity=27.6381909547739, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI21356301, Length=269, Percent_Identity=28.6245353159851, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI21357673, Length=147, Percent_Identity=27.891156462585, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 26986; Mature: 26855
Theoretical pI: Translated: 6.63; Mature: 6.63
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGRVSGKMALITGGAQGLGEATARMFAREGAKVTVTDVNGAGAEKVAASINEAHGPGTAF CCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCEE AFQHDVTSEEQWKDVAQKAHDAMGGLNILINNAGIGGLGSVEDETYERFRKVQAVDVDSI EEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCE FLGCKYSIPLMRDHGLGSIVNISSIAGIIASANYISYNTAKAAVRHMSKSIALHLAKTGG EEECEECCCEEECCCCCCEEHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHEEEEECCCC QIRCNSVHPVFINTPILDGIKEMFGEEKGLQKLARQVPLGKVGEPDDIAYAVLYLASDES EEEECCCCEEEEECHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCC KLVTGAELKVDGGISAM CEEECCEEEECCCCCCC >Mature Secondary Structure GRVSGKMALITGGAQGLGEATARMFAREGAKVTVTDVNGAGAEKVAASINEAHGPGTAF CCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCEE AFQHDVTSEEQWKDVAQKAHDAMGGLNILINNAGIGGLGSVEDETYERFRKVQAVDVDSI EEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCE FLGCKYSIPLMRDHGLGSIVNISSIAGIIASANYISYNTAKAAVRHMSKSIALHLAKTGG EEECEECCCEEECCCCCCEEHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHEEEEECCCC QIRCNSVHPVFINTPILDGIKEMFGEEKGLQKLARQVPLGKVGEPDDIAYAVLYLASDES EEEECCCCEEEEECHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCC KLVTGAELKVDGGISAM CEEECCEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7515041; 12450824 [H]