Click here to switch to the map view.

The map label for this gene is tldD [H]

Identifier: 114798375

GI number: 114798375

Start: 1043633

End: 1045036

Strand: Reverse

Name: tldD [H]

Synonym: HNE_1034

Alternate gene names: 114798375

Gene position: 1045036-1043633 (Counterclockwise)

Preceding gene: 114797233

Following gene: 114799605

Centisome position: 28.21

GC content: 65.46

Gene sequence:

>1404_bases
ATGACCCAATCTCCCCTGCCCTTTGACCTGACAGCCGCTTCCGCCATCCTGGCCGAAGCCACCCGCGGCGCCGATGATGG
CGACCTTTATGTGGAGCGGTCGCGCTCCGAGAGCTTCGTTTTTGACGATGGCCGGCTGAAATCGGCCGCCTATGACACCG
ATCAGGGCTTTGGCCTGCGGGTTGTGGCGGGCGAAGCGCAGGGCTCGGGCTATGCCTCGCAGCTGACCCTCGACGCCATT
CGCCGCGCAGGCGACACCGCCGCGCAGGCCAAACGCGGCCATTCCGGGACACTGGCGACCGGCCCGCAGCCAACCAACCG
CCGCCTTTACGCCCCCATCGACCCGACGCTGGCGCCGGCCTTTACCGACAAGACAAACCTTCTGGCCGAGATCGACGCCT
TTGCCCGCGCCAGCGACCCGCGCGTGGTGCAGGTGTCTGTGTCCCTCTCCGGCAGCCATAAGGAAATCGACATCCTGCGG
CCCGACGGCGCGCATTTTCATGAAGTGCGCCCGCTGGTGCGTCTCAATGTTTCCGTGACGCTGGAAGAGAACGGCCGGCG
CGAATCGGCCGGCGCAGGCGCAGGCGGACGCGCGGCCTATGATGAGTGGATTGCGCCCGAGCGCTGGAAGGCGATGGCGC
GGCGCGCGATTGAGAAGGCGTCTGTGAACCTCAAATCCATCCCCGCCCCGGCCGGCGAGATGGAAGTGGTGCTTGGCCCT
GGCTGGCCCGCTGTGCTGTTGCACGAGGCGGTTGGCCATGGCCTTGAAGGCGACTTCAACCGTAAGGGCACGAGCGTCTA
TTCCGGCCAGATCGGCCAGCAGGTTGCCGCCAGGGGCGTGACTGTAATTGATGACGGCTCGATCGAGGCGCGGCGCGGAT
CGCTGTCGTTTGATGACGAGGGCACGCCGACGCAGCGCACCGTGCTGATCGAAGACGGCATCCTCAAAGGCTATATGCAG
GACCGGATGAACGCCCGCCTGATGGGCATGGCGCCCACGGGCAATGGCCGGCGCGAAAGCTATGAAGCCCAGACCATGCC
GCGGATGACCAACACCGTGATGCTGGGCGGGGATAAAGACCCCGGCGAGATTGTCGCCTCGATCAAGCGCGGGCTTTGGG
CCGTGGATTTTGGCGGCGGACAGGTGGACATTACCTCCGGCAACTTCGTCTTTCAGTGCACGGAGGCTTACCTCGTCGAG
AATGGCAAGGTGGTTGCCCCGGTGAAGAATGCGACGCTGATCGGCCATGGGCCGACCGTGCTGCGCGATGTGACGATGAT
CGGCAATGACTTTGCCATGGATGACGGCGTGGGTGTGTGCGGCAAGGCCGGGCAGTCCATCCCCGTGGGCGTGGGCCAGC
CGACGCTGAAAGTCGGTTCCCTGACGGTTGGCGGGGCCGGGTAA

Upstream 100 bases:

>100_bases
GCCGAACAGGCGCTGAGCGCATTTCCGCCGGGCAAACCCGCAGGCTGAGGCTTGTAGAGAAGGCCTTGTATGGGGGCGCG
GAAGCCCGCATCTTGGGAAC

Downstream 100 bases:

>100_bases
GCCAGGGCGATGAACATCCAGTCCATCCTCGCGTCGATGTTTTCCCTGAAGGCGGAGACCCGCGCCGCGCCGCCCGTGCA
GCGCCTTTCGGCGCGCGAGG

Product: TldD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MTQSPLPFDLTAASAILAEATRGADDGDLYVERSRSESFVFDDGRLKSAAYDTDQGFGLRVVAGEAQGSGYASQLTLDAI
RRAGDTAAQAKRGHSGTLATGPQPTNRRLYAPIDPTLAPAFTDKTNLLAEIDAFARASDPRVVQVSVSLSGSHKEIDILR
PDGAHFHEVRPLVRLNVSVTLEENGRRESAGAGAGGRAAYDEWIAPERWKAMARRAIEKASVNLKSIPAPAGEMEVVLGP
GWPAVLLHEAVGHGLEGDFNRKGTSVYSGQIGQQVAARGVTVIDDGSIEARRGSLSFDDEGTPTQRTVLIEDGILKGYMQ
DRMNARLMGMAPTGNGRRESYEAQTMPRMTNTVMLGGDKDPGEIVASIKRGLWAVDFGGGQVDITSGNFVFQCTEAYLVE
NGKVVAPVKNATLIGHGPTVLRDVTMIGNDFAMDDGVGVCGKAGQSIPVGVGQPTLKVGSLTVGGAG

Sequences:

>Translated_467_residues
MTQSPLPFDLTAASAILAEATRGADDGDLYVERSRSESFVFDDGRLKSAAYDTDQGFGLRVVAGEAQGSGYASQLTLDAI
RRAGDTAAQAKRGHSGTLATGPQPTNRRLYAPIDPTLAPAFTDKTNLLAEIDAFARASDPRVVQVSVSLSGSHKEIDILR
PDGAHFHEVRPLVRLNVSVTLEENGRRESAGAGAGGRAAYDEWIAPERWKAMARRAIEKASVNLKSIPAPAGEMEVVLGP
GWPAVLLHEAVGHGLEGDFNRKGTSVYSGQIGQQVAARGVTVIDDGSIEARRGSLSFDDEGTPTQRTVLIEDGILKGYMQ
DRMNARLMGMAPTGNGRRESYEAQTMPRMTNTVMLGGDKDPGEIVASIKRGLWAVDFGGGQVDITSGNFVFQCTEAYLVE
NGKVVAPVKNATLIGHGPTVLRDVTMIGNDFAMDDGVGVCGKAGQSIPVGVGQPTLKVGSLTVGGAG
>Mature_466_residues
TQSPLPFDLTAASAILAEATRGADDGDLYVERSRSESFVFDDGRLKSAAYDTDQGFGLRVVAGEAQGSGYASQLTLDAIR
RAGDTAAQAKRGHSGTLATGPQPTNRRLYAPIDPTLAPAFTDKTNLLAEIDAFARASDPRVVQVSVSLSGSHKEIDILRP
DGAHFHEVRPLVRLNVSVTLEENGRRESAGAGAGGRAAYDEWIAPERWKAMARRAIEKASVNLKSIPAPAGEMEVVLGPG
WPAVLLHEAVGHGLEGDFNRKGTSVYSGQIGQQVAARGVTVIDDGSIEARRGSLSFDDEGTPTQRTVLIEDGILKGYMQD
RMNARLMGMAPTGNGRRESYEAQTMPRMTNTVMLGGDKDPGEIVASIKRGLWAVDFGGGQVDITSGNFVFQCTEAYLVEN
GKVVAPVKNATLIGHGPTVLRDVTMIGNDFAMDDGVGVCGKAGQSIPVGVGQPTLKVGSLTVGGAG

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=462, Percent_Identity=53.8961038961039, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI1790682, Length=446, Percent_Identity=23.7668161434978, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 49249; Mature: 49118

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSPLPFDLTAASAILAEATRGADDGDLYVERSRSESFVFDDGRLKSAAYDTDQGFGLR
CCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCCCEEE
VVAGEAQGSGYASQLTLDAIRRAGDTAAQAKRGHSGTLATGPQPTNRRLYAPIDPTLAPA
EEEECCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCC
FTDKTNLLAEIDAFARASDPRVVQVSVSLSGSHKEIDILRPDGAHFHEVRPLVRLNVSVT
CCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEECCCCCCHHHCCEEEEEEEEEE
LEENGRRESAGAGAGGRAAYDEWIAPERWKAMARRAIEKASVNLKSIPAPAGEMEVVLGP
ECCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECC
GWPAVLLHEAVGHGLEGDFNRKGTSVYSGQIGQQVAARGVTVIDDGSIEARRGSLSFDDE
CCHHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHCCCEEEECCCCEEECCCCCCCCC
GTPTQRTVLIEDGILKGYMQDRMNARLMGMAPTGNGRRESYEAQTMPRMTNTVMLGGDKD
CCCCEEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHCCCCCCEEEECCCCC
PGEIVASIKRGLWAVDFGGGQVDITSGNFVFQCTEAYLVENGKVVAPVKNATLIGHGPTV
HHHHHHHHHCCEEEEEECCCEEEEECCCEEEEEEEEEEEECCEEEEEECCCEEEECCCHH
LRDVTMIGNDFAMDDGVGVCGKAGQSIPVGVGQPTLKVGSLTVGGAG
HHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEECCEEECCCC
>Mature Secondary Structure 
TQSPLPFDLTAASAILAEATRGADDGDLYVERSRSESFVFDDGRLKSAAYDTDQGFGLR
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCCCEEE
VVAGEAQGSGYASQLTLDAIRRAGDTAAQAKRGHSGTLATGPQPTNRRLYAPIDPTLAPA
EEEECCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCC
FTDKTNLLAEIDAFARASDPRVVQVSVSLSGSHKEIDILRPDGAHFHEVRPLVRLNVSVT
CCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEECCCCCCHHHCCEEEEEEEEEE
LEENGRRESAGAGAGGRAAYDEWIAPERWKAMARRAIEKASVNLKSIPAPAGEMEVVLGP
ECCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECC
GWPAVLLHEAVGHGLEGDFNRKGTSVYSGQIGQQVAARGVTVIDDGSIEARRGSLSFDDE
CCHHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHCCCEEEECCCCEEECCCCCCCCC
GTPTQRTVLIEDGILKGYMQDRMNARLMGMAPTGNGRRESYEAQTMPRMTNTVMLGGDKD
CCCCEEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHCCCCCCEEEECCCCC
PGEIVASIKRGLWAVDFGGGQVDITSGNFVFQCTEAYLVENGKVVAPVKNATLIGHGPTV
HHHHHHHHHCCEEEEEECCCEEEEECCCEEEEEEEEEEEECCEEEEEECCCEEEECCCHH
LRDVTMIGNDFAMDDGVGVCGKAGQSIPVGVGQPTLKVGSLTVGGAG
HHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEECCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]