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The map label for this gene is gstA [H]

Identifier: 114798341

GI number: 114798341

Start: 319630

End: 320253

Strand: Direct

Name: gstA [H]

Synonym: HNE_0324

Alternate gene names: 114798341

Gene position: 319630-320253 (Clockwise)

Preceding gene: 114797102

Following gene: 114798651

Centisome position: 8.63

GC content: 63.14

Gene sequence:

>624_bases
ATGTCTGCCTCACACTATGGCGGGTTTACGCTTTACGGAGACCCCGTCTCCGGCAACTGCCTCAAGCCCAGATGGACCGC
TGACCTCCTCGGCATCCCCTACACATGGGTGGATGTGGACGTGGTGAAGGGCGAAACGCGCACGCCGCAATTTCTCGCCA
TGAACCCCGCCGGCCAGGTGCCCTTGGCGCGCTGGCCCGATGGCCGCACGCTGCCCCAGTCCAACGCCATCATGCTCTAT
CTCGCTGAAGGCTCAAGCCTTCTCCCAAGCGATGCCTTCGCCCGCGCCGAAGCGCTCAGCTGGCTCTTCTGGGAACAGTA
TTCCCATGAAACCGCCATCGCCGTGCGCCGTTTCCAGAAACACTATCTGAAGAAATCCGACACCGAGATCGACCCGGCGC
TTCTGGTGCGCGGCAACAATGCCCTCGGCGTGATGGAGCAGCGCCTCACGGGCCGCGACTGGTTTGCCGGCGGCGCGCTC
TCGGTCGCAGATATTGCCCTTGTCGCCTATACGCGCGTAGCGCATGAGGGCGGCTTCGATATTCGACTTTACCCGGCAGT
CGCGCGCTGGGTTTCCCGCACTGAAGATGCGCTGGGCGTCCCCCATGCGCAGGAGTTTGTCTGA

Upstream 100 bases:

>100_bases
ATGGCCAGATCACCGGCCGCGAGACGCTGCGCGAATCCCTGCGCGCGCACTTCTCCGAGGGCGGGTTAGACGGGGCAATG
AGCGAGCAGGAAACGGCCTG

Downstream 100 bases:

>100_bases
TGTATCGTTATGACCAATTCGACGCCCGCATTGTTGCCGAGCGTGTCGCCCAGTTCCGGGGGCAGGTGGCCCGCCGCCTG
TCCGGTGAGCTGCTGGAGGA

Product: glutathione S-transferase

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSASHYGGFTLYGDPVSGNCLKPRWTADLLGIPYTWVDVDVVKGETRTPQFLAMNPAGQVPLARWPDGRTLPQSNAIMLY
LAEGSSLLPSDAFARAEALSWLFWEQYSHETAIAVRRFQKHYLKKSDTEIDPALLVRGNNALGVMEQRLTGRDWFAGGAL
SVADIALVAYTRVAHEGGFDIRLYPAVARWVSRTEDALGVPHAQEFV

Sequences:

>Translated_207_residues
MSASHYGGFTLYGDPVSGNCLKPRWTADLLGIPYTWVDVDVVKGETRTPQFLAMNPAGQVPLARWPDGRTLPQSNAIMLY
LAEGSSLLPSDAFARAEALSWLFWEQYSHETAIAVRRFQKHYLKKSDTEIDPALLVRGNNALGVMEQRLTGRDWFAGGAL
SVADIALVAYTRVAHEGGFDIRLYPAVARWVSRTEDALGVPHAQEFV
>Mature_206_residues
SASHYGGFTLYGDPVSGNCLKPRWTADLLGIPYTWVDVDVVKGETRTPQFLAMNPAGQVPLARWPDGRTLPQSNAIMLYL
AEGSSLLPSDAFARAEALSWLFWEQYSHETAIAVRRFQKHYLKKSDTEIDPALLVRGNNALGVMEQRLTGRDWFAGGALS
VADIALVAYTRVAHEGGFDIRLYPAVARWVSRTEDALGVPHAQEFV

Specific function: Unknown

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=171, Percent_Identity=29.2397660818713, Blast_Score=68, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17864598, Length=191, Percent_Identity=28.2722513089005, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19922532, Length=204, Percent_Identity=28.921568627451, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24654992, Length=200, Percent_Identity=29, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24646249, Length=185, Percent_Identity=29.1891891891892, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI17864592, Length=184, Percent_Identity=27.7173913043478, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646251, Length=194, Percent_Identity=28.3505154639175, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 22909; Mature: 22778

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASHYGGFTLYGDPVSGNCLKPRWTADLLGIPYTWVDVDVVKGETRTPQFLAMNPAGQV
CCCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCEEEEEEEEECCCCCCCEEEEECCCCCC
PLARWPDGRTLPQSNAIMLYLAEGSSLLPSDAFARAEALSWLFWEQYSHETAIAVRRFQK
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
HYLKKSDTEIDPALLVRGNNALGVMEQRLTGRDWFAGGALSVADIALVAYTRVAHEGGFD
HHHCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCE
IRLYPAVARWVSRTEDALGVPHAQEFV
EEEHHHHHHHHHHCHHHCCCCCHHHCC
>Mature Secondary Structure 
SASHYGGFTLYGDPVSGNCLKPRWTADLLGIPYTWVDVDVVKGETRTPQFLAMNPAGQV
CCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCEEEEEEEEECCCCCCCEEEEECCCCCC
PLARWPDGRTLPQSNAIMLYLAEGSSLLPSDAFARAEALSWLFWEQYSHETAIAVRRFQK
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
HYLKKSDTEIDPALLVRGNNALGVMEQRLTGRDWFAGGALSVADIALVAYTRVAHEGGFD
HHHCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCE
IRLYPAVARWVSRTEDALGVPHAQEFV
EEEHHHHHHHHHHCHHHCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA