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The map label for this gene is oxaA [H]

Identifier: 114798266

GI number: 114798266

Start: 412663

End: 414483

Strand: Direct

Name: oxaA [H]

Synonym: HNE_0414

Alternate gene names: 114798266

Gene position: 412663-414483 (Clockwise)

Preceding gene: 114798810

Following gene: 114797282

Centisome position: 11.14

GC content: 62.0

Gene sequence:

>1821_bases
ATGGAACCACAAGAACAACGCAACTTCCTGATCGCCATGGCAGCGATGATCGCGTTCGTTTTCCTGTACCAGTATTTCGT
GATGGAGCCCGCCCAGAAGCGCTATGAGGCTGAACAGGCTGTGGCGGTTGCGGCGGAGCAGGCGGCTGTCACTGATACCG
GTGTCGCCGAAATTCTGGGGCCGAAGTCACTTGAGGATGCCCTGGCCGAAGATGGCCGGGTGAAGTTTGACGCCAATGCC
GTAGACGGCACGATCCGTCTGGCTGGCGCGCGCATTGATGATCTCAGCCTCAAACAATTTTACACCACGGTCGAGCGCGA
AGCGGAAATCCGCCTGCTGCGCCCCGAGGCGACCGAAGGGGCCTATTTCGGCACCTATTACTGGGCGGACGGGAACGCGC
TGGTTGCCGGGCGCAATTCGGTCTGGACGCAGGTAGGCGGCGACACGCTGACGACGGCCACGCCGGTCACCCTGCGCCTT
GAAACCGAAGGCATGACCATCGACCGCGAAATCTCGATCGATGCCAACTACATGTTCTCCTTCCGCGACACGCTGACCAA
TACGTCCGGCGCCGCGCGCACGGTCCGCGCCATCGGCTCGTTCGAGCGTCATGGCGACTGGAAGCGCTTCCTCGAAATCA
CAGATCCCGCCTCCGCCACCAGCGGCGGCCCGGCCCATCTCGGCCTCATGGGCGTGGCTGATGGCGAGCTGCGCCTGCAG
AAATACAAACCGCTGATGCAATCGAAGAAGATCAGCGGCGAATCGGGTGAGGGCACCTTTTTCTCGGACGAAGGCGGCTG
GTGGGGGCTGACCGACATGTACTGGATGGGCGCTCTGGTGCCTGAACAGGCCCGCCCTTTCACGGCCAGCGTCAACCGCG
CCAGCCTCGCGCGCGGCGGTCCGCTGGAAGTGCGCACCGAAGGCGCGGCCATCGAAGTGGCGCCCGGCGCCAGCGTAACC
GTGGAGAACGGCCTGTTTGCCGGCGCCAAGCAGTTTGAAGTGCTTCAGGGCTATGAGAAATCCGGCTTGCCGCGCTTTGT
CGACGCCATCGACTGGGGCTGGGCCTACTTCCTGACCAAGCCATTCTTCTACGTGCTGCATTGGCTCAACGGCTATCTCG
GCTCGTTCGGCTGGTCGATCCTGGCATTCACGGTTCTGGTGAAACTCCCCCTCGTGCCGCTCTACAATGCGAGCTTCAAA
TCGATGGCCAAGCTGAAGAAGCTGCAGGAGCCGATGAAGCAGCTCAATGAGCGCTTTGCCGCTGACCCTCAGCGCAAGCA
GCAGGAGCTGATGAAGCTCTACAAGGAGGAGGGGGCCAACCCCATCGGCGGCTGCCTGCCGATCCTCTTCACCATCCCGA
TCTTCTACGCGCTCTACAAGACGCTCTACGTCTCGCTGGAAATGCGCCATGCGCCGTTCGCTTACCTGAAGGACCTGTCC
GCGCCCGATCCGACCGCCATCGGCAACCTCTTCGGCCTGATCCCGTTCTGGTCCGGCGCTGACGTGAAAAGCATCCCGAT
CATCGGCATCATCATCGGCATCGGCATCCTGCCGATCCTCTATGGCGCGACCATGGCGGCGCTTCAGTCGCTCTCCCCGC
CGCCGCCTGACAAGATGCAGGCGCGCATCATCATGGCCATGCCGATCGTCTTCATGTTCGTCTTCGGCGGCTTTGCGGCG
GGCCTCGTGATGTACTGGGTCTGGTCGAACGTGCTGACCTTCATCCAGCAATACATCATTATGCGCATGAACGGCGTGGA
GACCGAGCTTGGCAAATTCGTTGCCACGCGGCTCGGGCTCAAGAAGGCGCAGGCGGAATAG

Upstream 100 bases:

>100_bases
GCTTGACGATATGGAAAGCGCGCTGATAAGCCTCGCGCGCACTTGACCCTAGCCCCGCGCCTGCCGGACCGGCACGCTCT
CAGCCCCGCGGACACCCGAC

Downstream 100 bases:

>100_bases
ATCTTGGACGCAGCAGCAGCCCCGGAATTTACCGAAGAAGCCCTGGAGGCTGGCCGGCTGCTGTTTGCGGGCAAGGCAGA
GTTTGTGATGGGCGTTGTGA

Product: inner membrane protein, 60 kDa

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MEPQEQRNFLIAMAAMIAFVFLYQYFVMEPAQKRYEAEQAVAVAAEQAAVTDTGVAEILGPKSLEDALAEDGRVKFDANA
VDGTIRLAGARIDDLSLKQFYTTVEREAEIRLLRPEATEGAYFGTYYWADGNALVAGRNSVWTQVGGDTLTTATPVTLRL
ETEGMTIDREISIDANYMFSFRDTLTNTSGAARTVRAIGSFERHGDWKRFLEITDPASATSGGPAHLGLMGVADGELRLQ
KYKPLMQSKKISGESGEGTFFSDEGGWWGLTDMYWMGALVPEQARPFTASVNRASLARGGPLEVRTEGAAIEVAPGASVT
VENGLFAGAKQFEVLQGYEKSGLPRFVDAIDWGWAYFLTKPFFYVLHWLNGYLGSFGWSILAFTVLVKLPLVPLYNASFK
SMAKLKKLQEPMKQLNERFAADPQRKQQELMKLYKEEGANPIGGCLPILFTIPIFYALYKTLYVSLEMRHAPFAYLKDLS
APDPTAIGNLFGLIPFWSGADVKSIPIIGIIIGIGILPILYGATMAALQSLSPPPPDKMQARIIMAMPIVFMFVFGGFAA
GLVMYWVWSNVLTFIQQYIIMRMNGVETELGKFVATRLGLKKAQAE

Sequences:

>Translated_606_residues
MEPQEQRNFLIAMAAMIAFVFLYQYFVMEPAQKRYEAEQAVAVAAEQAAVTDTGVAEILGPKSLEDALAEDGRVKFDANA
VDGTIRLAGARIDDLSLKQFYTTVEREAEIRLLRPEATEGAYFGTYYWADGNALVAGRNSVWTQVGGDTLTTATPVTLRL
ETEGMTIDREISIDANYMFSFRDTLTNTSGAARTVRAIGSFERHGDWKRFLEITDPASATSGGPAHLGLMGVADGELRLQ
KYKPLMQSKKISGESGEGTFFSDEGGWWGLTDMYWMGALVPEQARPFTASVNRASLARGGPLEVRTEGAAIEVAPGASVT
VENGLFAGAKQFEVLQGYEKSGLPRFVDAIDWGWAYFLTKPFFYVLHWLNGYLGSFGWSILAFTVLVKLPLVPLYNASFK
SMAKLKKLQEPMKQLNERFAADPQRKQQELMKLYKEEGANPIGGCLPILFTIPIFYALYKTLYVSLEMRHAPFAYLKDLS
APDPTAIGNLFGLIPFWSGADVKSIPIIGIIIGIGILPILYGATMAALQSLSPPPPDKMQARIIMAMPIVFMFVFGGFAA
GLVMYWVWSNVLTFIQQYIIMRMNGVETELGKFVATRLGLKKAQAE
>Mature_606_residues
MEPQEQRNFLIAMAAMIAFVFLYQYFVMEPAQKRYEAEQAVAVAAEQAAVTDTGVAEILGPKSLEDALAEDGRVKFDANA
VDGTIRLAGARIDDLSLKQFYTTVEREAEIRLLRPEATEGAYFGTYYWADGNALVAGRNSVWTQVGGDTLTTATPVTLRL
ETEGMTIDREISIDANYMFSFRDTLTNTSGAARTVRAIGSFERHGDWKRFLEITDPASATSGGPAHLGLMGVADGELRLQ
KYKPLMQSKKISGESGEGTFFSDEGGWWGLTDMYWMGALVPEQARPFTASVNRASLARGGPLEVRTEGAAIEVAPGASVT
VENGLFAGAKQFEVLQGYEKSGLPRFVDAIDWGWAYFLTKPFFYVLHWLNGYLGSFGWSILAFTVLVKLPLVPLYNASFK
SMAKLKKLQEPMKQLNERFAADPQRKQQELMKLYKEEGANPIGGCLPILFTIPIFYALYKTLYVSLEMRHAPFAYLKDLS
APDPTAIGNLFGLIPFWSGADVKSIPIIGIIIGIGILPILYGATMAALQSLSPPPPDKMQARIIMAMPIVFMFVFGGFAA
GLVMYWVWSNVLTFIQQYIIMRMNGVETELGKFVATRLGLKKAQAE

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=330, Percent_Identity=34.2424242424242, Blast_Score=189, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 66859; Mature: 66859

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPQEQRNFLIAMAAMIAFVFLYQYFVMEPAQKRYEAEQAVAVAAEQAAVTDTGVAEILG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCC
PKSLEDALAEDGRVKFDANAVDGTIRLAGARIDDLSLKQFYTTVEREAEIRLLRPEATEG
CCHHHHHHHCCCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCC
AYFGTYYWADGNALVAGRNSVWTQVGGDTLTTATPVTLRLETEGMTIDREISIDANYMFS
CEEEEEEEECCCEEEECCCCCEEECCCCEECCCCCEEEEEECCCCEEEEEEEECCCEEEE
FRDTLTNTSGAARTVRAIGSFERHGDWKRFLEITDPASATSGGPAHLGLMGVADGELRLQ
EHHHHCCCCCHHHHHHHHHCHHHCCCHHHHEEECCCCCCCCCCCCEEEEEEECCCHHHHH
KYKPLMQSKKISGESGEGTFFSDEGGWWGLTDMYWMGALVPEQARPFTASVNRASLARGG
HHHHHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHCCCC
PLEVRTEGAAIEVAPGASVTVENGLFAGAKQFEVLQGYEKSGLPRFVDAIDWGWAYFLTK
CEEEEECCCEEEECCCCCEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHH
PFFYVLHWLNGYLGSFGWSILAFTVLVKLPLVPLYNASFKSMAKLKKLQEPMKQLNERFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
ADPQRKQQELMKLYKEEGANPIGGCLPILFTIPIFYALYKTLYVSLEMRHAPFAYLKDLS
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCC
APDPTAIGNLFGLIPFWSGADVKSIPIIGIIIGIGILPILYGATMAALQSLSPPPPDKMQ
CCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
ARIIMAMPIVFMFVFGGFAAGLVMYWVWSNVLTFIQQYIIMRMNGVETELGKFVATRLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
KKAQAE
HHHCCC
>Mature Secondary Structure
MEPQEQRNFLIAMAAMIAFVFLYQYFVMEPAQKRYEAEQAVAVAAEQAAVTDTGVAEILG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCC
PKSLEDALAEDGRVKFDANAVDGTIRLAGARIDDLSLKQFYTTVEREAEIRLLRPEATEG
CCHHHHHHHCCCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCC
AYFGTYYWADGNALVAGRNSVWTQVGGDTLTTATPVTLRLETEGMTIDREISIDANYMFS
CEEEEEEEECCCEEEECCCCCEEECCCCEECCCCCEEEEEECCCCEEEEEEEECCCEEEE
FRDTLTNTSGAARTVRAIGSFERHGDWKRFLEITDPASATSGGPAHLGLMGVADGELRLQ
EHHHHCCCCCHHHHHHHHHCHHHCCCHHHHEEECCCCCCCCCCCCEEEEEEECCCHHHHH
KYKPLMQSKKISGESGEGTFFSDEGGWWGLTDMYWMGALVPEQARPFTASVNRASLARGG
HHHHHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHCCCC
PLEVRTEGAAIEVAPGASVTVENGLFAGAKQFEVLQGYEKSGLPRFVDAIDWGWAYFLTK
CEEEEECCCEEEECCCCCEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHH
PFFYVLHWLNGYLGSFGWSILAFTVLVKLPLVPLYNASFKSMAKLKKLQEPMKQLNERFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
ADPQRKQQELMKLYKEEGANPIGGCLPILFTIPIFYALYKTLYVSLEMRHAPFAYLKDLS
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCC
APDPTAIGNLFGLIPFWSGADVKSIPIIGIIIGIGILPILYGATMAALQSLSPPPPDKMQ
CCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
ARIIMAMPIVFMFVFGGFAAGLVMYWVWSNVLTFIQQYIIMRMNGVETELGKFVATRLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
KKAQAE
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA