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The map label for this gene is czcB [H]

Identifier: 114798025

GI number: 114798025

Start: 2468562

End: 2469785

Strand: Direct

Name: czcB [H]

Synonym: HNE_2372

Alternate gene names: 114798025

Gene position: 2468562-2469785 (Clockwise)

Preceding gene: 114798628

Following gene: 114798897

Centisome position: 66.63

GC content: 67.89

Gene sequence:

>1224_bases
GTGCTGGTTGCCTGCGGGGCGGCAGACCCGGACACGGCCGGTCAGGCCGCGCCAGATCATGCCCATGAGGCGGACAAAGC
CGGACAGATCGGGACAGACGCGGACGCCGATCACGGGGACGAGGACGACCATGACCACGGCCATGAAAAGGCCGAGGGCG
ACCATGTGGAGCTGTCTGCCGAGGCGGCCCGTGACGCCGGAATCGTGATCGCGGCGGCCGAGCTTGCCGCGCTGCCTTCA
ACCCTGAAACTGCCCGCTGAAATCCGCTTTGATGCAGACCGGATCGCCAATGTGACGGCGAGCCTTGAGGGCATTGTCGC
CCGCGTGGAGGCGCGCGAGGGCGCCGTTGTACGCAAGGGCGCGACACTGGCAGTGCTGCGCAGCCGGGAGCTGGCGGGCC
TGAAGGCGGACTATCTGACGGCCGCCTCCACCGAAATGCTCGCCCGCGACACGCTGATGCGGGAGGAGCGGCTATGGGAG
CACCGGGTGACGCCGGAAGCCGACCTGCAAGCCGCCCGCGCGGGTGTGGCTGCCGCAGAGGCCGCGCGCAAGGCCGCGGA
GAACAAGCTGCATGCCGTCGGCGTCAGCGACGGCGCGCTGGAGAAGATGGTGGAGGCGCCCGATGGAGGCCTCGCCAGCG
CATCTATCCTTGCCCCGATTGGCGGCACTATCGTGCGCCGCAACCTCTCCCTGGGCGACATGGTGACCACGGAAGTGACC
GCGCCGCTGTTCGTCATCGCGGACGCCAGCGTGCTGTGGGCCGATATTGCCGTCTACAAGAATGACTATGGCCGCCTGCG
CGAGGGTATGGCTGTGACGCTGCGCCTGGAGACGGGCGACATCGCCGCCGAAGGCACCATCGGTCTCATCTTGCCACTGA
TCGAGGAAACCTCCCGCACGGCGACGGCACGGGTGATCCTCGACAATAAGGACGGGCGGCTGCGCCCCGGCCAGTTCGTG
ACGGCGGAGATCGCGGCGGGGACAAGCGCGGCGGTGCTGCGCGTGCCTGAAGGGTCCATCGTGGAGGTGGAGGGGACACC
GTCGGTGTTCGTGCCAACCGAGGACGGCTTTGAATCGCGCGCCGTTGAAACCGGCGGCAAGGCCGGAGGCTATGCCGAAA
TCCGATCCGGCCTTGAGACCGGCGACCGCTACGTATCCGAGGGCGCCTTCACGCTGAAAGCTCAGCTGGAAAAAGACGCG
TTCGGCGACGGCCACGCGCATTAG

Upstream 100 bases:

>100_bases
TTTCAAGATCGAATGCGCCTGTCGGGCGCGGGCTCTGCTTTTGCGGGGCAGTATGTTTAATAAAATCAATAGGTTGATAG
GCGCTGCGTCGCTGGCGTTC

Downstream 100 bases:

>100_bases
GAGGCGGCACACATGACATCCCTGATGCACCACATTGCGGGCGGACGCCTGCTGGCCGCCATCGCTGTTCTTGCGCTGAC
GCTGGGGGGCCTGTTTGCCT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MLVACGAADPDTAGQAAPDHAHEADKAGQIGTDADADHGDEDDHDHGHEKAEGDHVELSAEAARDAGIVIAAAELAALPS
TLKLPAEIRFDADRIANVTASLEGIVARVEAREGAVVRKGATLAVLRSRELAGLKADYLTAASTEMLARDTLMREERLWE
HRVTPEADLQAARAGVAAAEAARKAAENKLHAVGVSDGALEKMVEAPDGGLASASILAPIGGTIVRRNLSLGDMVTTEVT
APLFVIADASVLWADIAVYKNDYGRLREGMAVTLRLETGDIAAEGTIGLILPLIEETSRTATARVILDNKDGRLRPGQFV
TAEIAAGTSAAVLRVPEGSIVEVEGTPSVFVPTEDGFESRAVETGGKAGGYAEIRSGLETGDRYVSEGAFTLKAQLEKDA
FGDGHAH

Sequences:

>Translated_407_residues
MLVACGAADPDTAGQAAPDHAHEADKAGQIGTDADADHGDEDDHDHGHEKAEGDHVELSAEAARDAGIVIAAAELAALPS
TLKLPAEIRFDADRIANVTASLEGIVARVEAREGAVVRKGATLAVLRSRELAGLKADYLTAASTEMLARDTLMREERLWE
HRVTPEADLQAARAGVAAAEAARKAAENKLHAVGVSDGALEKMVEAPDGGLASASILAPIGGTIVRRNLSLGDMVTTEVT
APLFVIADASVLWADIAVYKNDYGRLREGMAVTLRLETGDIAAEGTIGLILPLIEETSRTATARVILDNKDGRLRPGQFV
TAEIAAGTSAAVLRVPEGSIVEVEGTPSVFVPTEDGFESRAVETGGKAGGYAEIRSGLETGDRYVSEGAFTLKAQLEKDA
FGDGHAH
>Mature_407_residues
MLVACGAADPDTAGQAAPDHAHEADKAGQIGTDADADHGDEDDHDHGHEKAEGDHVELSAEAARDAGIVIAAAELAALPS
TLKLPAEIRFDADRIANVTASLEGIVARVEAREGAVVRKGATLAVLRSRELAGLKADYLTAASTEMLARDTLMREERLWE
HRVTPEADLQAARAGVAAAEAARKAAENKLHAVGVSDGALEKMVEAPDGGLASASILAPIGGTIVRRNLSLGDMVTTEVT
APLFVIADASVLWADIAVYKNDYGRLREGMAVTLRLETGDIAAEGTIGLILPLIEETSRTATARVILDNKDGRLRPGQFV
TAEIAAGTSAAVLRVPEGSIVEVEGTPSVFVPTEDGFESRAVETGGKAGGYAEIRSGLETGDRYVSEGAFTLKAQLEKDA
FGDGHAH

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Inner Membrane By A Lipid Anchor [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=314, Percent_Identity=27.0700636942675, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786668, Length=341, Percent_Identity=24.633431085044, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789665, Length=360, Percent_Identity=23.8888888888889, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42415; Mature: 42415

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVACGAADPDTAGQAAPDHAHEADKAGQIGTDADADHGDEDDHDHGHEKAEGDHVELSA
CEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEH
EAARDAGIVIAAAELAALPSTLKLPAEIRFDADRIANVTASLEGIVARVEAREGAVVRKG
HHCCCCCEEEEEHHHHHCCCHHCCCCEEEECHHHHHHHHHHHHHHHHEEECCCCCEEECC
ATLAVLRSRELAGLKADYLTAASTEMLARDTLMREERLWEHRVTPEADLQAARAGVAAAE
CEEEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AARKAAENKLHAVGVSDGALEKMVEAPDGGLASASILAPIGGTIVRRNLSLGDMVTTEVT
HHHHHHHCCEEEEECCCHHHHHHHHCCCCCCCCHHHHHCCCCEEEEECCCCCCEEEHHHC
APLFVIADASVLWADIAVYKNDYGRLREGMAVTLRLETGDIAAEGTIGLILPLIEETSRT
CCEEEEECCHHHHHHHHHHHCCHHHHCCCCEEEEEEECCCEECCCCCEEEEHHHHHCCCC
ATARVILDNKDGRLRPGQFVTAEIAAGTSAAVLRVPEGSIVEVEGTPSVFVPTEDGFESR
EEEEEEEECCCCCCCCCCEEEEEECCCCCEEEEECCCCCEEEECCCCCEEEECCCCCCHH
AVETGGKAGGYAEIRSGLETGDRYVSEGAFTLKAQLEKDAFGDGHAH
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLVACGAADPDTAGQAAPDHAHEADKAGQIGTDADADHGDEDDHDHGHEKAEGDHVELSA
CEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEH
EAARDAGIVIAAAELAALPSTLKLPAEIRFDADRIANVTASLEGIVARVEAREGAVVRKG
HHCCCCCEEEEEHHHHHCCCHHCCCCEEEECHHHHHHHHHHHHHHHHEEECCCCCEEECC
ATLAVLRSRELAGLKADYLTAASTEMLARDTLMREERLWEHRVTPEADLQAARAGVAAAE
CEEEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AARKAAENKLHAVGVSDGALEKMVEAPDGGLASASILAPIGGTIVRRNLSLGDMVTTEVT
HHHHHHHCCEEEEECCCHHHHHHHHCCCCCCCCHHHHHCCCCEEEEECCCCCCEEEHHHC
APLFVIADASVLWADIAVYKNDYGRLREGMAVTLRLETGDIAAEGTIGLILPLIEETSRT
CCEEEEECCHHHHHHHHHHHCCHHHHCCCCEEEEEEECCCEECCCCCEEEEHHHHHCCCC
ATARVILDNKDGRLRPGQFVTAEIAAGTSAAVLRVPEGSIVEVEGTPSVFVPTEDGFESR
EEEEEEEECCCCCCCCCCEEEEEECCCCCEEEEECCCCCEEEECCCCCEEEECCCCCCHH
AVETGGKAGGYAEIRSGLETGDRYVSEGAFTLKAQLEKDAFGDGHAH
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]