Definition Hyphomonas neptunium ATCC 15444 chromosome, complete genome.
Accession NC_008358
Length 3,705,021

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The map label for this gene is lolD [C]

Identifier: 114797981

GI number: 114797981

Start: 173147

End: 173842

Strand: Direct

Name: lolD [C]

Synonym: HNE_0186

Alternate gene names: 114797981

Gene position: 173147-173842 (Clockwise)

Preceding gene: 114798529

Following gene: 114800526

Centisome position: 4.67

GC content: 64.22

Gene sequence:

>696_bases
ATGGCTGACCCGGTTATTGATATCGAAGGGCTGCGCTTTGCCTGGAAGAGCGGCCCGCAGGTGCTCGACATGGATACGTT
TCGTGTCGATGCCGGAGAGCGCGTGTTCCTGCGGGGACCGTCGGGCTCTGGGAAATCCACGCTGCTCGGCCTGATCGCCG
GCGTTCTTCAGCCCCAGGCGGGGCGCATCTGCGTGTTGGGCGAAGATATGAACGTGCTCAAAGCTGGCCGCCGCGACAGG
CTGCGCGCTGACCGGATGGGCGTGATATTCCAGATGTTCAATCTGGTGCCGTATCTGTCGGTAACGGGAAACGTCCTGCT
GCCGCTGCGCTTTTCCCCGGCGCGCCGGATGGCTGCCGGAAATGATCCGCAGGCGGAAGCCCGCAGGTTGTTGGCGCGGC
TGGGTCTGGAAGATAAAGAGTTGCTGGAGCGCCGGGTATCAGACCTGTCTGTCGGGCAACAACAGCGCGTGGCGGCCGCG
CGTGCCCTTATCGGCAGCCCGAGCCTCGTCATCGCCGACGAGCCGACTTCAGCCCTCGACGCCGACGCGCGGGACCGGTT
CATCACCCTGCTCTCCGAAGAGGTAGAGCGGTCAGGCGCAACGCTTCTGTTCGTCAGTCATGACGCATCCCTCGCCGGAT
TGTTTACGCGCGCTGCCGATCTCACGGCAATAAACCGGGCAGGGGCGCCGGCATGA

Upstream 100 bases:

>100_bases
GTTTTGAAACGATCAATGCCGTCTTTGTTGGCGATACGGTTCAGAAAGCCGCAGAGCTGACGCCTTCCTCCCCAGAGCTT
TCCCTGAAATAACGGCTGAG

Downstream 100 bases:

>100_bases
CCGCCCTGTTTTCGCTGGCCTGGGCAAGCCTTCTGAACCGCAAGGGCTCAGTGATCCTTACGATTGTCGCCGTCGCGCTG
TCGGTTGCGTTGTTTCTCGG

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MADPVIDIEGLRFAWKSGPQVLDMDTFRVDAGERVFLRGPSGSGKSTLLGLIAGVLQPQAGRICVLGEDMNVLKAGRRDR
LRADRMGVIFQMFNLVPYLSVTGNVLLPLRFSPARRMAAGNDPQAEARRLLARLGLEDKELLERRVSDLSVGQQQRVAAA
RALIGSPSLVIADEPTSALDADARDRFITLLSEEVERSGATLLFVSHDASLAGLFTRAADLTAINRAGAPA

Sequences:

>Translated_231_residues
MADPVIDIEGLRFAWKSGPQVLDMDTFRVDAGERVFLRGPSGSGKSTLLGLIAGVLQPQAGRICVLGEDMNVLKAGRRDR
LRADRMGVIFQMFNLVPYLSVTGNVLLPLRFSPARRMAAGNDPQAEARRLLARLGLEDKELLERRVSDLSVGQQQRVAAA
RALIGSPSLVIADEPTSALDADARDRFITLLSEEVERSGATLLFVSHDASLAGLFTRAADLTAINRAGAPA
>Mature_230_residues
ADPVIDIEGLRFAWKSGPQVLDMDTFRVDAGERVFLRGPSGSGKSTLLGLIAGVLQPQAGRICVLGEDMNVLKAGRRDRL
RADRMGVIFQMFNLVPYLSVTGNVLLPLRFSPARRMAAGNDPQAEARRLLARLGLEDKELLERRVSDLSVGQQQRVAAAR
ALIGSPSLVIADEPTSALDADARDRFITLLSEEVERSGATLLFVSHDASLAGLFTRAADLTAINRAGAPA

Specific function: Part Of The Abc Transporter Complex Lolcde Involved In The Translocation Of Mature Outer Membrane-Directed Lipoproteins, From The Inner Membrane To The Periplasmic Chaperone, Lola. Responsible For The Formation Of The Lola-Lipoprotein Complex In An ATP-De

COG id: COG1136

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9665248, Length=209, Percent_Identity=30.1435406698565, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI42490749, Length=205, Percent_Identity=29.2682926829268, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI255708477, Length=228, Percent_Identity=28.9473684210526, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI9955968, Length=212, Percent_Identity=28.7735849056604, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI9955966, Length=212, Percent_Identity=28.7735849056604, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI45243524, Length=212, Percent_Identity=28.7735849056604, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI105990541, Length=196, Percent_Identity=30.1020408163265, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI42741659, Length=225, Percent_Identity=28, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI156105685, Length=215, Percent_Identity=29.7674418604651, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI150417984, Length=210, Percent_Identity=29.0476190476191, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI11967969, Length=236, Percent_Identity=28.8135593220339, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI87081834, Length=204, Percent_Identity=37.2549019607843, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1789873, Length=207, Percent_Identity=40.0966183574879, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1786703, Length=214, Percent_Identity=35.981308411215, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787105, Length=221, Percent_Identity=33.9366515837104, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1787029, Length=208, Percent_Identity=39.4230769230769, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1786398, Length=213, Percent_Identity=35.2112676056338, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786563, Length=196, Percent_Identity=36.2244897959184, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87081791, Length=225, Percent_Identity=34.6666666666667, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786253, Length=183, Percent_Identity=37.1584699453552, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1789672, Length=216, Percent_Identity=36.5740740740741, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1788761, Length=209, Percent_Identity=36.3636363636364, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1787089, Length=210, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87081709, Length=192, Percent_Identity=36.9791666666667, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787370, Length=211, Percent_Identity=34.1232227488152, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI87082267, Length=203, Percent_Identity=34.4827586206897, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1788225, Length=209, Percent_Identity=35.4066985645933, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790467, Length=205, Percent_Identity=34.1463414634146, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787712, Length=183, Percent_Identity=36.0655737704918, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1786872, Length=174, Percent_Identity=38.5057471264368, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1790544, Length=219, Percent_Identity=35.6164383561644, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787759, Length=241, Percent_Identity=31.9502074688797, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787500, Length=210, Percent_Identity=30.4761904761905, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI145693107, Length=221, Percent_Identity=33.4841628959276, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1786319, Length=213, Percent_Identity=29.1079812206573, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788506, Length=220, Percent_Identity=36.3636363636364, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI48994997, Length=221, Percent_Identity=32.1266968325792, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789962, Length=205, Percent_Identity=31.219512195122, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1790534, Length=195, Percent_Identity=33.8461538461538, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790190, Length=205, Percent_Identity=30.2439024390244, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI48994883, Length=222, Percent_Identity=31.5315315315315, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1789891, Length=223, Percent_Identity=31.8385650224215, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1787758, Length=187, Percent_Identity=32.620320855615, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788644, Length=203, Percent_Identity=32.512315270936, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48995001, Length=208, Percent_Identity=32.2115384615385, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87081782, Length=185, Percent_Identity=31.8918918918919, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788053, Length=186, Percent_Identity=34.9462365591398, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790525, Length=215, Percent_Identity=26.9767441860465, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789032, Length=205, Percent_Identity=29.7560975609756, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787164, Length=192, Percent_Identity=36.9791666666667, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1788450, Length=172, Percent_Identity=37.2093023255814, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789963, Length=216, Percent_Identity=30.5555555555556, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787547, Length=209, Percent_Identity=29.6650717703349, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788210, Length=195, Percent_Identity=31.2820512820513, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1789864, Length=225, Percent_Identity=26.2222222222222, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789991, Length=191, Percent_Identity=30.8900523560209, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788897, Length=191, Percent_Identity=34.0314136125654, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1787548, Length=231, Percent_Identity=28.1385281385281, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786981, Length=198, Percent_Identity=32.8282828282828, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788472, Length=192, Percent_Identity=30.7291666666667, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI48994943, Length=190, Percent_Identity=30, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786975, Length=202, Percent_Identity=33.1683168316832, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790162, Length=196, Percent_Identity=32.1428571428571, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790739, Length=196, Percent_Identity=29.0816326530612, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789586, Length=191, Percent_Identity=32.9842931937173, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787792, Length=197, Percent_Identity=28.9340101522843, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788165, Length=194, Percent_Identity=28.8659793814433, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=206, Percent_Identity=29.126213592233, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71996809, Length=213, Percent_Identity=30.5164319248826, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193211015, Length=213, Percent_Identity=30.5164319248826, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193211017, Length=213, Percent_Identity=30.5164319248826, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71983516, Length=192, Percent_Identity=30.7291666666667, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71983510, Length=192, Percent_Identity=30.7291666666667, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71983523, Length=192, Percent_Identity=30.7291666666667, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565586, Length=191, Percent_Identity=34.0314136125654, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17510237, Length=217, Percent_Identity=26.7281105990783, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=210, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17541710, Length=230, Percent_Identity=30, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI115533608, Length=203, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17567265, Length=203, Percent_Identity=30.0492610837438, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193202349, Length=205, Percent_Identity=29.2682926829268, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=190, Percent_Identity=28.4210526315789, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115535101, Length=212, Percent_Identity=32.5471698113208, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567269, Length=200, Percent_Identity=29.5, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17569143, Length=216, Percent_Identity=29.1666666666667, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324985, Length=208, Percent_Identity=25.9615384615385, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323217, Length=228, Percent_Identity=28.5087719298246, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323959, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24666092, Length=210, Percent_Identity=30.952380952381, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281363262, Length=204, Percent_Identity=31.8627450980392, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24653245, Length=204, Percent_Identity=31.8627450980392, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI85726357, Length=227, Percent_Identity=30.8370044052863, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24643674, Length=196, Percent_Identity=29.5918367346939, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221512771, Length=182, Percent_Identity=27.4725274725275, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17136662, Length=204, Percent_Identity=29.9019607843137, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28571209, Length=211, Percent_Identity=26.5402843601896, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641565, Length=226, Percent_Identity=32.3008849557522, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 24891; Mature: 24760

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MADPVIDIEGLRFAWKSGPQVLDMDTFRVDAGERVFLRGPSGSGKSTLLGLIAGVLQPQA
CCCCCEECCCCEEEECCCCEEEECCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCC
GRICVLGEDMNVLKAGRRDRLRADRMGVIFQMFNLVPYLSVTGNVLLPLRFSPARRMAAG
CEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEECHHHHHCCC
NDPQAEARRLLARLGLEDKELLERRVSDLSVGQQQRVAAARALIGSPSLVIADEPTSALD
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCC
ADARDRFITLLSEEVERSGATLLFVSHDASLAGLFTRAADLTAINRAGAPA
CCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ADPVIDIEGLRFAWKSGPQVLDMDTFRVDAGERVFLRGPSGSGKSTLLGLIAGVLQPQA
CCCCEECCCCEEEECCCCEEEECCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCC
GRICVLGEDMNVLKAGRRDRLRADRMGVIFQMFNLVPYLSVTGNVLLPLRFSPARRMAAG
CEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEECHHHHHCCC
NDPQAEARRLLARLGLEDKELLERRVSDLSVGQQQRVAAARALIGSPSLVIADEPTSALD
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCC
ADARDRFITLLSEEVERSGATLLFVSHDASLAGLFTRAADLTAINRAGAPA
CCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]