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The map label for this gene is qseB [H]

Identifier: 114797742

GI number: 114797742

Start: 2460918

End: 2461580

Strand: Direct

Name: qseB [H]

Synonym: HNE_2361

Alternate gene names: 114797742

Gene position: 2460918-2461580 (Clockwise)

Preceding gene: 114797770

Following gene: 114798979

Centisome position: 66.42

GC content: 63.8

Gene sequence:

>663_bases
ATGCGCGTACTCCTCGTTGAAGACGAAGTCCTGATTGCAGACGATATTTCGGCCGCCCTGAAAGATTCCGGCTTTATGGT
AGACCTCGCCCGCGACGGCGAAGACGCCTGGTTCAAGGGCGATACCGAACCCTATGACGCGATCATTCTGGACCTCGGCC
TGCCCCGGATGGACGGCCTCTCGGTCCTCAAACGCTGGCGCGCTGCGGGCATGATCACGCCCATCCTCATCCTCTCTGCC
CGCGGCAGCTGGATGGAGCGGGTCGATGGCATCGAGGCCGGCGCCGATGACTACCTGCCTAAACCCTTTGAAATGGCGGA
GCTAATCGTTCGCCTACGCGCCCTCATCCGCCGCGCCGCCGGCATGGCTCAGCCCGTGCTTCAGGCCGGCGACCTGATGG
TCGATACCCGCCGCATGACCATCGCCTATGCCGGCCAGCCCGTGCGCGTCACGCCCCTGGAATTTCGCCTGGTGGACTAT
CTTGTCCACAACATGAACCGCACGGTTTCGGCCGGTGAACTCTCCGAACACCTTCACGGCGTTGAAGACACCGGCGACAC
CAACGCCATCGAGGCCATTGTCTCACGCCTGCGCCGCAAGCTTGGCCCGGGCGTGATCAGCACCCGGCGCGGTTTCGGCT
ACGTCATCGAAGCGGGCGCGTGA

Upstream 100 bases:

>100_bases
TGATCTATGAGATCGAAGTGCTGACTCGCCGGGGAACTGTGCTGGAAATGGACGTTGATGCCCGTACTGGCCGCATCCTC
GACATCGAAGAGGATGACTG

Downstream 100 bases:

>100_bases
GGCCCCTGCGATCCATCCGGCTTCGCCTGCTAGCAGGCGGCGCGCTGGCCATTGCGGCCGCCCTGCTGGTTTCATGGTTC
ACGCTTGTGCTGCTGTTCGA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MRVLLVEDEVLIADDISAALKDSGFMVDLARDGEDAWFKGDTEPYDAIILDLGLPRMDGLSVLKRWRAAGMITPILILSA
RGSWMERVDGIEAGADDYLPKPFEMAELIVRLRALIRRAAGMAQPVLQAGDLMVDTRRMTIAYAGQPVRVTPLEFRLVDY
LVHNMNRTVSAGELSEHLHGVEDTGDTNAIEAIVSRLRRKLGPGVISTRRGFGYVIEAGA

Sequences:

>Translated_220_residues
MRVLLVEDEVLIADDISAALKDSGFMVDLARDGEDAWFKGDTEPYDAIILDLGLPRMDGLSVLKRWRAAGMITPILILSA
RGSWMERVDGIEAGADDYLPKPFEMAELIVRLRALIRRAAGMAQPVLQAGDLMVDTRRMTIAYAGQPVRVTPLEFRLVDY
LVHNMNRTVSAGELSEHLHGVEDTGDTNAIEAIVSRLRRKLGPGVISTRRGFGYVIEAGA
>Mature_220_residues
MRVLLVEDEVLIADDISAALKDSGFMVDLARDGEDAWFKGDTEPYDAIILDLGLPRMDGLSVLKRWRAAGMITPILILSA
RGSWMERVDGIEAGADDYLPKPFEMAELIVRLRALIRRAAGMAQPVLQAGDLMVDTRRMTIAYAGQPVRVTPLEFRLVDY
LVHNMNRTVSAGELSEHLHGVEDTGDTNAIEAIVSRLRRKLGPGVISTRRGFGYVIEAGA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=43.37899543379, Blast_Score=174, Evalue=3e-45,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=36.1990950226244, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=37.8378378378378, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=33.7899543378995, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=31.651376146789, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=33.0316742081448, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=35.3448275862069, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=33.7837837837838, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.4841628959276, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=30.3964757709251, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=31.5789473684211, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=28.8888888888889, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=24.6696035242291, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=33.6206896551724, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=106, Percent_Identity=31.1320754716981, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24219; Mature: 24219

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLVEDEVLIADDISAALKDSGFMVDLARDGEDAWFKGDTEPYDAIILDLGLPRMDGL
CEEEEECCCEEEEHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHEEEEECCCCCCCHH
SVLKRWRAAGMITPILILSARGSWMERVDGIEAGADDYLPKPFEMAELIVRLRALIRRAA
HHHHHHHHCCCHHHHHHEECCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GMAQPVLQAGDLMVDTRRMTIAYAGQPVRVTPLEFRLVDYLVHNMNRTVSAGELSEHLHG
CHHHHHHHCCCEEEECEEEEEEECCCCEEECHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
VEDTGDTNAIEAIVSRLRRKLGPGVISTRRGFGYVIEAGA
CCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCEEEECCC
>Mature Secondary Structure
MRVLLVEDEVLIADDISAALKDSGFMVDLARDGEDAWFKGDTEPYDAIILDLGLPRMDGL
CEEEEECCCEEEEHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHEEEEECCCCCCCHH
SVLKRWRAAGMITPILILSARGSWMERVDGIEAGADDYLPKPFEMAELIVRLRALIRRAA
HHHHHHHHCCCHHHHHHEECCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GMAQPVLQAGDLMVDTRRMTIAYAGQPVRVTPLEFRLVDYLVHNMNRTVSAGELSEHLHG
CHHHHHHHCCCEEEECEEEEEEECCCCEEECHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
VEDTGDTNAIEAIVSRLRRKLGPGVISTRRGFGYVIEAGA
CCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]