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The map label for this gene is fucA [H]

Identifier: 114797608

GI number: 114797608

Start: 2527861

End: 2528514

Strand: Direct

Name: fucA [H]

Synonym: HNE_2420

Alternate gene names: 114797608

Gene position: 2527861-2528514 (Clockwise)

Preceding gene: 114797283

Following gene: 114800178

Centisome position: 68.23

GC content: 61.47

Gene sequence:

>654_bases
ATGAGCGAACAGGAAACAAAGCTGCGCGAGCAGGTGGTTGAGGTGATGGCGGCGATGGATGCGCGCGGCCTGAACCGGGG
CACTTCGGGCAATGTGTCGGCGCGGCTGGGCGAGGATATGCTGGTGACGCCGACGGGGGTTCCGCCCTCGATGCTGGCGC
CGGAACATATCGTGCGGATGGCGCCGGATGGGAGCTTTGATCCAGCGGGCATGAAGCCGTCGAGCGAATGGCAGATGCAC
TGGAAACTGTTGCAGCTGCGCCAGGATGTGAACGCCGTGGTGCATTGCCATTCTCGCTTTGCAACGACGCTGGCCTGCGC
GAACAAGCCCATCCCTGCCCTGCATTATATGGTGGCTGTGAGCGGGGGGCCTTCTGTGCCGGTGGCGCCTTATGCGACAT
TTGGATCTGCTGAGTTGGCCGAGGCCGTTTGCGAGACACTTTCGGGACAATTCGGGACACTTATGGCCAATCACGGACAA
ATCGTGGTCGCGCCGAGCCTCAAACAGGCGCTTCTGATCGCCGAGGAGATTGAGGAACAGGCGGCCATCTATTGGGGCAC
GTTGGCCATCGGCGGACCGACCCTACTGGCCGATGATGAGATGACGCGCATCGCTGACCGGTTCCGGTCCTATGGGCAGA
AGAAGAAGCCTTGA

Upstream 100 bases:

>100_bases
CGATGGTGGCCCAGGGGCTGGCGACGTATGGTAAGCTGGAGAGCTTTGATCAGGTGGAAGCGGCGATGAAAACCCTTCCG
ATTCAGGAGGCTGGCGCATG

Downstream 100 bases:

>100_bases
TCCAAGGTGCGGCGGGATTGCGCTTGCGCATACGGTAATGATGGCTACCATTAGTCCAGAGTGATTGATGGGAGCCCCCT
ATGCTGGCCTGCTATACTGA

Product: putative L-ribulose-5-phosphate 4-epimerase

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MSEQETKLREQVVEVMAAMDARGLNRGTSGNVSARLGEDMLVTPTGVPPSMLAPEHIVRMAPDGSFDPAGMKPSSEWQMH
WKLLQLRQDVNAVVHCHSRFATTLACANKPIPALHYMVAVSGGPSVPVAPYATFGSAELAEAVCETLSGQFGTLMANHGQ
IVVAPSLKQALLIAEEIEEQAAIYWGTLAIGGPTLLADDEMTRIADRFRSYGQKKKP

Sequences:

>Translated_217_residues
MSEQETKLREQVVEVMAAMDARGLNRGTSGNVSARLGEDMLVTPTGVPPSMLAPEHIVRMAPDGSFDPAGMKPSSEWQMH
WKLLQLRQDVNAVVHCHSRFATTLACANKPIPALHYMVAVSGGPSVPVAPYATFGSAELAEAVCETLSGQFGTLMANHGQ
IVVAPSLKQALLIAEEIEEQAAIYWGTLAIGGPTLLADDEMTRIADRFRSYGQKKKP
>Mature_216_residues
SEQETKLREQVVEVMAAMDARGLNRGTSGNVSARLGEDMLVTPTGVPPSMLAPEHIVRMAPDGSFDPAGMKPSSEWQMHW
KLLQLRQDVNAVVHCHSRFATTLACANKPIPALHYMVAVSGGPSVPVAPYATFGSAELAEAVCETLSGQFGTLMANHGQI
VVAPSLKQALLIAEEIEEQAAIYWGTLAIGGPTLLADDEMTRIADRFRSYGQKKKP

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789164, Length=212, Percent_Identity=42.9245283018868, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI1789094, Length=188, Percent_Identity=33.5106382978723, Blast_Score=93, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004782 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 23356; Mature: 23225

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQETKLREQVVEVMAAMDARGLNRGTSGNVSARLGEDMLVTPTGVPPSMLAPEHIVRM
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCHHHHEEE
APDGSFDPAGMKPSSEWQMHWKLLQLRQDVNAVVHCHSRFATTLACANKPIPALHYMVAV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
SGGPSVPVAPYATFGSAELAEAVCETLSGQFGTLMANHGQIVVAPSLKQALLIAEEIEEQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHH
AAIYWGTLAIGGPTLLADDEMTRIADRFRSYGQKKKP
HHEEEEEEEECCCEEECCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEQETKLREQVVEVMAAMDARGLNRGTSGNVSARLGEDMLVTPTGVPPSMLAPEHIVRM
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCHHHHEEE
APDGSFDPAGMKPSSEWQMHWKLLQLRQDVNAVVHCHSRFATTLACANKPIPALHYMVAV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
SGGPSVPVAPYATFGSAELAEAVCETLSGQFGTLMANHGQIVVAPSLKQALLIAEEIEEQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHH
AAIYWGTLAIGGPTLLADDEMTRIADRFRSYGQKKKP
HHEEEEEEEECCCEEECCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]