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The map label for this gene is aroC

Identifier: 114797430

GI number: 114797430

Start: 845285

End: 846376

Strand: Reverse

Name: aroC

Synonym: HNE_0823

Alternate gene names: 114797430

Gene position: 846376-845285 (Counterclockwise)

Preceding gene: 114798862

Following gene: 114799517

Centisome position: 22.84

GC content: 65.2

Gene sequence:

>1092_bases
ATGTCGCATAACACATTTGGCCACCTTTTCCGCGTCACGACCTGGGGCGAAAGCCATGGGCCGGCCCTTGGCTGCGTCAT
TGACGGCTGCCCGCCAGGACTTTCGCTGGACGCTCCGTTCATCCAGCAGTTCCTGGACAAGCGGCGGCCGGGAACTTCCC
GTTTCGTGACCCAGCGCCAGGAAGCCGATGAGGTGAAGATCCTCTCCGGCGTGTTCGAGGACGACCGCACAGATGGCCCG
GTCACCACCGGCACGCCGATCTCGCTGATGATCGAAAACACCGACCAGCGCTCCAAAGATTACCGCGAAATCCGCGACCG
CTACCGCCCCGGCCATGCCGATTATGCCTATGACCAGAAATACGGCGTGCGCGACTATCGCGGCGGGGGGCGCTCCTCGG
CGCGCGAAACCGCCGCGCGGGTGGCCGCTGGCGCCGTTGCCCGGCGGGTGCTCGGCGAGGACATTCTTCTGCGCGGCGCC
GTCGTGCAGATCGGGCCACACATGATCGACCCGAAAAACTGGGACTGGGCGGAAACGCAGAACAACCCCTTCTGGTGCCC
GGACGCGAAGATGGCCGCGCAATGGGAAACCTATCTGGACAGCGTCCGTAAATCCGGCAGCTCAACAGGCGCGATTGTCG
AAGTTCACGCCTCTGGTGTTCCCGCCGGCTGGGGCGCGCCGGTCTATGGCAAGCTCGACGCGGAGCTGGCCGGGGCAATG
ATGAGCATCAACGCCGCCAAGGGCGTCGAAATCGGCGCTGGCTTTGCGGCCGCCTCCATGAGCGGCGAAGAAAATGCCGA
CGAGATGCGGGCGGGCAATGATGCGCCGCGTTTCCTGGCCAACAACAATGGCGGCGTCGCGGGCGGCATTTCCACAGGGC
AGGACATAGTCGTCCGTATCGCGATCAAACCGACCTCCTCCATCCTGAACGAAGTCAAATCGATCACGCGGGATGGCGAG
GAAGTGGACGTGCGCACCATTGGCCGCCACGACCCCTGCGTCGGCATCCGCGCGGTGCCGGTGGCCGAGGCGATGCTGGC
CTGTGTGCTGGCAGATGCGAAGCTGCGCCACCGGGGGCAGACGGGCCACTGA

Upstream 100 bases:

>100_bases
TTACAGAAGACGTCATGGGACGGCCCACCTTTTCGCGGTTTGTAAGGCTTCGTTTTTCATATAGGACGAGGCCCGCAGCC
GCGAGAGGATAGCCTGTCAC

Downstream 100 bases:

>100_bases
ACACTAACTCTTCTGCCTGATGAACAAAAAAACCCCAGCGCGTTCTGCGCCGGGGTTTTCGAGTTGAGGTAAGCAGGGAA
AGCTTAGAAGCGAACCACTG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSHNTFGHLFRVTTWGESHGPALGCVIDGCPPGLSLDAPFIQQFLDKRRPGTSRFVTQRQEADEVKILSGVFEDDRTDGP
VTTGTPISLMIENTDQRSKDYREIRDRYRPGHADYAYDQKYGVRDYRGGGRSSARETAARVAAGAVARRVLGEDILLRGA
VVQIGPHMIDPKNWDWAETQNNPFWCPDAKMAAQWETYLDSVRKSGSSTGAIVEVHASGVPAGWGAPVYGKLDAELAGAM
MSINAAKGVEIGAGFAAASMSGEENADEMRAGNDAPRFLANNNGGVAGGISTGQDIVVRIAIKPTSSILNEVKSITRDGE
EVDVRTIGRHDPCVGIRAVPVAEAMLACVLADAKLRHRGQTGH

Sequences:

>Translated_363_residues
MSHNTFGHLFRVTTWGESHGPALGCVIDGCPPGLSLDAPFIQQFLDKRRPGTSRFVTQRQEADEVKILSGVFEDDRTDGP
VTTGTPISLMIENTDQRSKDYREIRDRYRPGHADYAYDQKYGVRDYRGGGRSSARETAARVAAGAVARRVLGEDILLRGA
VVQIGPHMIDPKNWDWAETQNNPFWCPDAKMAAQWETYLDSVRKSGSSTGAIVEVHASGVPAGWGAPVYGKLDAELAGAM
MSINAAKGVEIGAGFAAASMSGEENADEMRAGNDAPRFLANNNGGVAGGISTGQDIVVRIAIKPTSSILNEVKSITRDGE
EVDVRTIGRHDPCVGIRAVPVAEAMLACVLADAKLRHRGQTGH
>Mature_362_residues
SHNTFGHLFRVTTWGESHGPALGCVIDGCPPGLSLDAPFIQQFLDKRRPGTSRFVTQRQEADEVKILSGVFEDDRTDGPV
TTGTPISLMIENTDQRSKDYREIRDRYRPGHADYAYDQKYGVRDYRGGGRSSARETAARVAAGAVARRVLGEDILLRGAV
VQIGPHMIDPKNWDWAETQNNPFWCPDAKMAAQWETYLDSVRKSGSSTGAIVEVHASGVPAGWGAPVYGKLDAELAGAMM
SINAAKGVEIGAGFAAASMSGEENADEMRAGNDAPRFLANNNGGVAGGISTGQDIVVRIAIKPTSSILNEVKSITRDGEE
VDVRTIGRHDPCVGIRAVPVAEAMLACVLADAKLRHRGQTGH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=362, Percent_Identity=57.7348066298343, Blast_Score=390, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6321290, Length=373, Percent_Identity=42.0911528150134, Blast_Score=281, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_HYPNA (Q0C3Z3)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_759550.1
- ProteinModelPortal:   Q0C3Z3
- STRING:   Q0C3Z3
- GeneID:   4287167
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_0823
- NMPDR:   fig|228405.5.peg.805
- TIGR:   HNE_0823
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   Q0C3Z3
- ProtClustDB:   PRK05382
- BioCyc:   HNEP81032:HNE_0823-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39015; Mature: 38884

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNTFGHLFRVTTWGESHGPALGCVIDGCPPGLSLDAPFIQQFLDKRRPGTSRFVTQRQ
CCCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
EADEVKILSGVFEDDRTDGPVTTGTPISLMIENTDQRSKDYREIRDRYRPGHADYAYDQK
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCC
YGVRDYRGGGRSSARETAARVAAGAVARRVLGEDILLRGAVVQIGPHMIDPKNWDWAETQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCEECCCCCCCCCCCC
NNPFWCPDAKMAAQWETYLDSVRKSGSSTGAIVEVHASGVPAGWGAPVYGKLDAELAGAM
CCCEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHH
MSINAAKGVEIGAGFAAASMSGEENADEMRAGNDAPRFLANNNGGVAGGISTGQDIVVRI
HCCCCCCCCEECCCCCEECCCCCCCHHHHHCCCCCCCEEECCCCCEECCCCCCCEEEEEE
AIKPTSSILNEVKSITRDGEEVDVRTIGRHDPCVGIRAVPVAEAMLACVLADAKLRHRGQ
EECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCC
TGH
CCC
>Mature Secondary Structure 
SHNTFGHLFRVTTWGESHGPALGCVIDGCPPGLSLDAPFIQQFLDKRRPGTSRFVTQRQ
CCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
EADEVKILSGVFEDDRTDGPVTTGTPISLMIENTDQRSKDYREIRDRYRPGHADYAYDQK
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCC
YGVRDYRGGGRSSARETAARVAAGAVARRVLGEDILLRGAVVQIGPHMIDPKNWDWAETQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCEECCCCCCCCCCCC
NNPFWCPDAKMAAQWETYLDSVRKSGSSTGAIVEVHASGVPAGWGAPVYGKLDAELAGAM
CCCEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHH
MSINAAKGVEIGAGFAAASMSGEENADEMRAGNDAPRFLANNNGGVAGGISTGQDIVVRI
HCCCCCCCCEECCCCCEECCCCCCCHHHHHCCCCCCCEEECCCCCEECCCCCCCEEEEEE
AIKPTSSILNEVKSITRDGEEVDVRTIGRHDPCVGIRAVPVAEAMLACVLADAKLRHRGQ
EECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCC
TGH
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA