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The map label for this gene is serB [C]

Identifier: 114797368

GI number: 114797368

Start: 448141

End: 449040

Strand: Direct

Name: serB [C]

Synonym: HNE_0453

Alternate gene names: 114797368

Gene position: 448141-449040 (Clockwise)

Preceding gene: 114798870

Following gene: 114799399

Centisome position: 12.1

GC content: 65.67

Gene sequence:

>900_bases
ATGGATTGGGTCTTGGTTGCTGTCTCCAGCGCGGCAGATGCCCGCCTCGGCGAGCTGGCAAAAAATTCAGTCAGCGCCGT
TGGTGGCACACCAAACGGCTGGTCCAGCCTCTCCGATACCGGCCCGCTTCAGGCCGGCGCCCTGCGCTTTTCAGCCGCCA
GCGAGAGCCTCGGCGCCCTCCGCGCCGCGCTGGAAGCGGCTGGCCCCATCGATGCCGCCATCCTCCCCGCCGCCCGCTTC
GGCAGGAAACGCCTTATCATCTCCGACATGGACTCCACCATCATCGGCCAGGAATGCATCGACGAAATCGCTGACGCGGT
CGGCCTCAAAGCCAAAATCTCGGAAATCACCGAACGCGCCATGCGCGGCGAGTTGGATTTCGAGGCTGCCCTGACAGAAC
GCGTCGCCATGCTGAAGGGCCTGCCGCTGGACGCGCTCGCCCGCACGCTGGAAGAGCGCATCACGCTGAACCCCGGCGCC
CGCACACTCATCGCCACAATGAAAGCCCACGGCGCCGCCACGCTGCTCGTCTCAGGCGGCTTCACCTATTTCACCTCCCG
TGTTGCCGCCCTTGCAGGCTTTGAAAGCCATCAGGGCAACACGCTCATAGATGACGGCGCCGCGCTGACCGGCGAAGTCG
GCCAGCCCATCCTCGGGCGCGTCGCCAAACGCACCGCGCTTCTGGAGGCTGCCGCCAGCCTTGGCGCCGCTGCGGAAGAC
GCGATCGCCATGGGCGACGGGGCGAATGATCTCGACATGATCCGCGCCTCCGGTCTCGGCGTTGCCTACAAGGCAAAGCC
GGTGGTGGCTGCCGAGGCTGCCGGGTCCATCCGCCATACGGACTTGACGGCGGCCTTGTTCTTCCAAGGATACAAGGCGT
CCGAATTTGTCCGGGGATGA

Upstream 100 bases:

>100_bases
ATCAGGATCGCAGGGTGCATCCCCTACAACTAAGGACTTGCGAGCCCTGAGGAAAGCCACCTAGAGACGGCCTGCTTCGA
AGAGGGCCTTGAGAATGCAC

Downstream 100 bases:

>100_bases
CCGGAAATGTCCAAACTCCGCACACGCCTGTTCCAGTCCTGGTTCCGCCTCAGCCGCCCGATGACCCTCGGCGTGCGCGC
CGCGGTGGAGAATGAGGCGG

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDWVLVAVSSAADARLGELAKNSVSAVGGTPNGWSSLSDTGPLQAGALRFSAASESLGALRAALEAAGPIDAAILPAARF
GRKRLIISDMDSTIIGQECIDEIADAVGLKAKISEITERAMRGELDFEAALTERVAMLKGLPLDALARTLEERITLNPGA
RTLIATMKAHGAATLLVSGGFTYFTSRVAALAGFESHQGNTLIDDGAALTGEVGQPILGRVAKRTALLEAAASLGAAAED
AIAMGDGANDLDMIRASGLGVAYKAKPVVAAEAAGSIRHTDLTAALFFQGYKASEFVRG

Sequences:

>Translated_299_residues
MDWVLVAVSSAADARLGELAKNSVSAVGGTPNGWSSLSDTGPLQAGALRFSAASESLGALRAALEAAGPIDAAILPAARF
GRKRLIISDMDSTIIGQECIDEIADAVGLKAKISEITERAMRGELDFEAALTERVAMLKGLPLDALARTLEERITLNPGA
RTLIATMKAHGAATLLVSGGFTYFTSRVAALAGFESHQGNTLIDDGAALTGEVGQPILGRVAKRTALLEAAASLGAAAED
AIAMGDGANDLDMIRASGLGVAYKAKPVVAAEAAGSIRHTDLTAALFFQGYKASEFVRG
>Mature_299_residues
MDWVLVAVSSAADARLGELAKNSVSAVGGTPNGWSSLSDTGPLQAGALRFSAASESLGALRAALEAAGPIDAAILPAARF
GRKRLIISDMDSTIIGQECIDEIADAVGLKAKISEITERAMRGELDFEAALTERVAMLKGLPLDALARTLEERITLNPGA
RTLIATMKAHGAATLLVSGGFTYFTSRVAALAGFESHQGNTLIDDGAALTGEVGQPILGRVAKRTALLEAAASLGAAAED
AIAMGDGANDLDMIRASGLGVAYKAKPVVAAEAAGSIRHTDLTAALFFQGYKASEFVRG

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=105, Percent_Identity=37.1428571428571, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1790849, Length=199, Percent_Identity=43.21608040201, Blast_Score=135, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6321647, Length=240, Percent_Identity=31.25, Blast_Score=132, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24661601, Length=208, Percent_Identity=27.4038461538462, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 30680; Mature: 30680

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWVLVAVSSAADARLGELAKNSVSAVGGTPNGWSSLSDTGPLQAGALRFSAASESLGAL
CCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHEEEHHHHHHHHHH
RAALEAAGPIDAAILPAARFGRKRLIISDMDSTIIGQECIDEIADAVGLKAKISEITERA
HHHHHHCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
MRGELDFEAALTERVAMLKGLPLDALARTLEERITLNPGARTLIATMKAHGAATLLVSGG
HCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCHHHHHHHHHHCCCEEEEEECC
FTYFTSRVAALAGFESHQGNTLIDDGAALTGEVGQPILGRVAKRTALLEAAASLGAAAED
HHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
AIAMGDGANDLDMIRASGLGVAYKAKPVVAAEAAGSIRHTDLTAALFFQGYKASEFVRG
HEEECCCCCHHHHHHHCCCCEEEECCCEEEHHCCCCCCHHHHHHHHHHCCCCHHHHCCC
>Mature Secondary Structure
MDWVLVAVSSAADARLGELAKNSVSAVGGTPNGWSSLSDTGPLQAGALRFSAASESLGAL
CCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHEEEHHHHHHHHHH
RAALEAAGPIDAAILPAARFGRKRLIISDMDSTIIGQECIDEIADAVGLKAKISEITERA
HHHHHHCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
MRGELDFEAALTERVAMLKGLPLDALARTLEERITLNPGARTLIATMKAHGAATLLVSGG
HCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCHHHHHHHHHHCCCEEEEEECC
FTYFTSRVAALAGFESHQGNTLIDDGAALTGEVGQPILGRVAKRTALLEAAASLGAAAED
HHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
AIAMGDGANDLDMIRASGLGVAYKAKPVVAAEAAGSIRHTDLTAALFFQGYKASEFVRG
HEEECCCCCHHHHHHHCCCCEEEECCCEEEHHCCCCCCHHHHHHHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]