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The map label for this gene is fabH [H]

Identifier: 114797280

GI number: 114797280

Start: 876077

End: 877198

Strand: Reverse

Name: fabH [H]

Synonym: HNE_0857

Alternate gene names: 114797280

Gene position: 877198-876077 (Counterclockwise)

Preceding gene: 114798297

Following gene: 114799013

Centisome position: 23.68

GC content: 61.05

Gene sequence:

>1122_bases
ATGCCGAGCCCCGTGATTTCCGCCACTGGTCTGTGGACCCCGCCCAACTCGATTTCCAACGCTGAACTGGTCGCCAGCTA
CAATGCCTGGGCCGACAACTGGAATGTCGAGAACGCCGCCGACATCAGCTCCGGCCTGCTGGAGCCCAAAACCCATTCCT
CCGTCGAGTTCATCGAGAAGGCCTCGGGCATCAAGGCGCGCTATGTGATCGACAAGGAGGGCGTGCTGAACCCCGATATC
ATGACCCCGCGCATTCCTGAGCGGCCGAATGAACAGATTTCCGTACTGGCCGAAATGGCCGTGCATGCCGCGCGCGACGC
GCTCAAGCGGGCCGGGCGCGACCCGAAGGACATCGGCGCGGTGATCTGCGCGGCGTCCAACATGCAGCGCGCCTATCCGG
CGATGGCGATTGAAGTGCAGGAAGCGCTCGGCATCGAGGGATTTGCGTTTGATATGAACGTGGCCTGCTCCTCAGCCACG
TTCGGCATTCAGACGGCGGCGGACTTTATCCGCTCGGGCAATGCCAGATCGGTGCTGGTGGTGAACCCCGAAATCTGTTC
GGGCCATCTCAACTTCACCGACCGCGACAGCCATTTCATCTTTGGTGATGTGGCCACCGCCATCCTGGTAGAAGACGAGG
CGATTGCCCCGGCCGGGCACTGGAAGATCCTGGGTTCGCGGCTGAAGACGCAATTTTCCAACAACATCCGCAACAATTTC
GGCTTCCTGAACCGCGCGGCGCCTGACGGCATCGGCACGCCGGACAAGCTGTTCGTTCAGGAAGGCCGCAAGGTGTTCAA
GGAAGTGGTGCCGATGGTGGCAGAGATGATCAATGGTCATCTGGGCGAACTGGGCATCGAGGCGGGCGCTCTGAAACGCA
TGTGGCTGCATCAGGCCAACGCCAACATGAACCGGCTGATCTCATCGAAGGTGCTGGGCCATGAGGCGAGCGACGCTGAA
AGCCCTACAGTGCTCGACACCTACGCCAACACGTCTTCGGCGGGCTCGATCATCGCCTTCCATCTGCACTCGGAAGACTT
CACGGCCGGACAGAAAGGCCTGATCTGCTCGTTCGGAGCAGGCTATTCGGCTGGAACTGTTGTGGTGGAGCGGGTGGGCT
GA

Upstream 100 bases:

>100_bases
CCTTGTGCTTTGCCCGCAACGCGCGTTACAGCTTTCCCTACAAGGATATAGCTAGAAGGGCCTGACGCTTGCGCGCGGAC
AGGCGCCGCCGGAGACCCCT

Downstream 100 bases:

>100_bases
TCGCCCGGAAACGACTATTCGTCGAAGTCTTCGGTGAACAGGTCGCCCCAGAGGGCGCGGCGGCTGGCTTTGGCCGCCTC
GATGACCACAATGATGGCAC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MPSPVISATGLWTPPNSISNAELVASYNAWADNWNVENAADISSGLLEPKTHSSVEFIEKASGIKARYVIDKEGVLNPDI
MTPRIPERPNEQISVLAEMAVHAARDALKRAGRDPKDIGAVICAASNMQRAYPAMAIEVQEALGIEGFAFDMNVACSSAT
FGIQTAADFIRSGNARSVLVVNPEICSGHLNFTDRDSHFIFGDVATAILVEDEAIAPAGHWKILGSRLKTQFSNNIRNNF
GFLNRAAPDGIGTPDKLFVQEGRKVFKEVVPMVAEMINGHLGELGIEAGALKRMWLHQANANMNRLISSKVLGHEASDAE
SPTVLDTYANTSSAGSIIAFHLHSEDFTAGQKGLICSFGAGYSAGTVVVERVG

Sequences:

>Translated_373_residues
MPSPVISATGLWTPPNSISNAELVASYNAWADNWNVENAADISSGLLEPKTHSSVEFIEKASGIKARYVIDKEGVLNPDI
MTPRIPERPNEQISVLAEMAVHAARDALKRAGRDPKDIGAVICAASNMQRAYPAMAIEVQEALGIEGFAFDMNVACSSAT
FGIQTAADFIRSGNARSVLVVNPEICSGHLNFTDRDSHFIFGDVATAILVEDEAIAPAGHWKILGSRLKTQFSNNIRNNF
GFLNRAAPDGIGTPDKLFVQEGRKVFKEVVPMVAEMINGHLGELGIEAGALKRMWLHQANANMNRLISSKVLGHEASDAE
SPTVLDTYANTSSAGSIIAFHLHSEDFTAGQKGLICSFGAGYSAGTVVVERVG
>Mature_372_residues
PSPVISATGLWTPPNSISNAELVASYNAWADNWNVENAADISSGLLEPKTHSSVEFIEKASGIKARYVIDKEGVLNPDIM
TPRIPERPNEQISVLAEMAVHAARDALKRAGRDPKDIGAVICAASNMQRAYPAMAIEVQEALGIEGFAFDMNVACSSATF
GIQTAADFIRSGNARSVLVVNPEICSGHLNFTDRDSHFIFGDVATAILVEDEAIAPAGHWKILGSRLKTQFSNNIRNNFG
FLNRAAPDGIGTPDKLFVQEGRKVFKEVVPMVAEMINGHLGELGIEAGALKRMWLHQANANMNRLISSKVLGHEASDAES
PTVLDTYANTSSAGSIIAFHLHSEDFTAGQKGLICSFGAGYSAGTVVVERVG

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=327, Percent_Identity=26.9113149847095, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 39950; Mature: 39818

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPVISATGLWTPPNSISNAELVASYNAWADNWNVENAADISSGLLEPKTHSSVEFIEK
CCCCCEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHH
ASGIKARYVIDKEGVLNPDIMTPRIPERPNEQISVLAEMAVHAARDALKRAGRDPKDIGA
HCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHE
VICAASNMQRAYPAMAIEVQEALGIEGFAFDMNVACSSATFGIQTAADFIRSGNARSVLV
EEEECCCHHHHCCHHEEEHHHHHCCCCEEEECEEEECCCCCCHHHHHHHHHCCCCCEEEE
VNPEICSGHLNFTDRDSHFIFGDVATAILVEDEAIAPAGHWKILGSRLKTQFSNNIRNNF
ECHHHHCCCCCCCCCCCCEEEHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GFLNRAAPDGIGTPDKLFVQEGRKVFKEVVPMVAEMINGHLGELGIEAGALKRMWLHQAN
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCC
ANMNRLISSKVLGHEASDAESPTVLDTYANTSSAGSIIAFHLHSEDFTAGQKGLICSFGA
CCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEECCC
GYSAGTVVVERVG
CCCCCEEEEEECC
>Mature Secondary Structure 
PSPVISATGLWTPPNSISNAELVASYNAWADNWNVENAADISSGLLEPKTHSSVEFIEK
CCCCEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHH
ASGIKARYVIDKEGVLNPDIMTPRIPERPNEQISVLAEMAVHAARDALKRAGRDPKDIGA
HCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHE
VICAASNMQRAYPAMAIEVQEALGIEGFAFDMNVACSSATFGIQTAADFIRSGNARSVLV
EEEECCCHHHHCCHHEEEHHHHHCCCCEEEECEEEECCCCCCHHHHHHHHHCCCCCEEEE
VNPEICSGHLNFTDRDSHFIFGDVATAILVEDEAIAPAGHWKILGSRLKTQFSNNIRNNF
ECHHHHCCCCCCCCCCCCEEEHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GFLNRAAPDGIGTPDKLFVQEGRKVFKEVVPMVAEMINGHLGELGIEAGALKRMWLHQAN
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCC
ANMNRLISSKVLGHEASDAESPTVLDTYANTSSAGSIIAFHLHSEDFTAGQKGLICSFGA
CCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEECCC
GYSAGTVVVERVG
CCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA