BacMap

Definition	Hyphomonas neptunium ATCC 15444 chromosome, complete genome.
Accession	NC_008358
Length	3,705,021

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The map label for this gene is ligD [H]

Identifier: 114797103

GI number: 114797103

Start: 919253

End: 920101

Strand: Reverse

Name: ligD [H]

Synonym: HNE_0901

Alternate gene names: 114797103

Gene position: 920101-919253 (Counterclockwise)

Preceding gene: 114798468

Following gene: 114799089

Centisome position: 24.83

GC content: 62.54

Gene sequence:

>849_bases
ATGAAACATCTGGAAGGAAAGACCGCGTTCGTGACCGGCGCGGCGTCTGGCATTGGCCTGGGCATTGCCACGGCGCTGGC
GCAGGCGGGCGTGAAGGTGATGCTGTGCGACATCGAGAAGGCGGCGCTGGACAAGGCCGTTGCCACCTTGCGCGAGACCA
ATGCCGATGTGGACGGCGTGGTGGCGGACGTGTCGCTGAAGGACAATCTGCAACGCGCGGCCGACGAGACCATCGCGCGG
TTTGGCAAGGTGCATATCCTCGTCAACAATGCCGGCGTGGGCGGCGGGGGCGATTATGGCACCTGGAATGATGCGGGCTG
GAACTGGGTGGTGGGCGTCAATCTGATGTCTGTGGTTTGGGGCATCGAGATTTTCGGGCCGCTGATCGAAGCACATGGCG
AGGGCGGACAGATTGTGTCCACCGCGTCGATTGCCGGTATGGTGGCACTGACCAACCCTGCCTATGATGTGACGAAGTTT
GGCGTGGTGGCGCTGTCGGAAGATCTGCGACCGAAGCTGGCCGCGCGCGGGATTGGCGTCTCGGTGCTCTGCCCCGGCGT
GATCCGCACGAATATCGTGGACTCAGGGCGCAATATCCCGAGCCGCTTTGCCGGACAGATCCAGACGGTTCCGACCGAAG
GACCGGGGACGGAAATTCTCAAAGCCGTGACCGAGGCGATCGCGAGCGGGATTGATCCGCTCTATGTGGGCGAGCTGGTG
CGCGAGGCGATCGAGAATGACTGGCCGCATATTTTCACCGACATGCAGTTTGAGCCGCACATTGAGGCGAGGTTTGCGGC
GATCAAGGAGGGGTTTGACCGGATACGGGACCGGGTGCCCCGGTACTGA

Upstream 100 bases:

>100_bases
GAGCAGCCGCCTTTGGCGATGACGCAGGGTGAGGCCCCCGCCGCGATTGCGCGGGTGATTTTCGTGGCGCAGGGTGGCCG
CAAAAATCGGGAGGAAATCA

Downstream 100 bases:

>100_bases
GTCCCTCTCCCTACCCCTTCAGCATATCGCGCGAGATAATCACCCGCATCACTTCGTTGGTGCCTTCGAGGATCTGGTGG
ACCCTCAAGTCACGGACGAT

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKHLEGKTAFVTGAASGIGLGIATALAQAGVKVMLCDIEKAALDKAVATLRETNADVDGVVADVSLKDNLQRAADETIAR
FGKVHILVNNAGVGGGGDYGTWNDAGWNWVVGVNLMSVVWGIEIFGPLIEAHGEGGQIVSTASIAGMVALTNPAYDVTKF
GVVALSEDLRPKLAARGIGVSVLCPGVIRTNIVDSGRNIPSRFAGQIQTVPTEGPGTEILKAVTEAIASGIDPLYVGELV
REAIENDWPHIFTDMQFEPHIEARFAAIKEGFDRIRDRVPRY

Sequences:

>Translated_282_residues
MKHLEGKTAFVTGAASGIGLGIATALAQAGVKVMLCDIEKAALDKAVATLRETNADVDGVVADVSLKDNLQRAADETIAR
FGKVHILVNNAGVGGGGDYGTWNDAGWNWVVGVNLMSVVWGIEIFGPLIEAHGEGGQIVSTASIAGMVALTNPAYDVTKF
GVVALSEDLRPKLAARGIGVSVLCPGVIRTNIVDSGRNIPSRFAGQIQTVPTEGPGTEILKAVTEAIASGIDPLYVGELV
REAIENDWPHIFTDMQFEPHIEARFAAIKEGFDRIRDRVPRY
>Mature_282_residues
MKHLEGKTAFVTGAASGIGLGIATALAQAGVKVMLCDIEKAALDKAVATLRETNADVDGVVADVSLKDNLQRAADETIAR
FGKVHILVNNAGVGGGGDYGTWNDAGWNWVVGVNLMSVVWGIEIFGPLIEAHGEGGQIVSTASIAGMVALTNPAYDVTKF
GVVALSEDLRPKLAARGIGVSVLCPGVIRTNIVDSGRNIPSRFAGQIQTVPTEGPGTEILKAVTEAIASGIDPLYVGELV
REAIENDWPHIFTDMQFEPHIEARFAAIKEGFDRIRDRVPRY

Specific function: Catalyzes the C alpha dehydrogenation of arylglycerol- beta-aryl ether (C alpha alcohol type) (compound IV) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI31542939, Length=205, Percent_Identity=34.1463414634146, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI142976729, Length=198, Percent_Identity=31.8181818181818, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI224922801, Length=186, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI40807363, Length=245, Percent_Identity=27.7551020408163, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI32483357, Length=197, Percent_Identity=31.4720812182741, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI5031737, Length=196, Percent_Identity=29.5918367346939, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI22507405, Length=217, Percent_Identity=29.9539170506912, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI310128830, Length=257, Percent_Identity=24.9027237354086, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI310115468, Length=257, Percent_Identity=24.9027237354086, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=30.4123711340206, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI19743808, Length=279, Percent_Identity=26.5232974910394, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI150247226, Length=208, Percent_Identity=29.8076923076923, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI109715829, Length=202, Percent_Identity=27.2277227722772, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI210032110, Length=194, Percent_Identity=27.8350515463918, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI40548397, Length=210, Percent_Identity=27.1428571428571, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI214010158, Length=210, Percent_Identity=27.1428571428571, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI214010156, Length=210, Percent_Identity=27.1428571428571, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI22758144, Length=210, Percent_Identity=27.1428571428571, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=30.3191489361702, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI19923817, Length=228, Percent_Identity=26.7543859649123, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI87082100, Length=244, Percent_Identity=34.4262295081967, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789208, Length=212, Percent_Identity=30.6603773584906, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1786701, Length=213, Percent_Identity=31.924882629108, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787335, Length=193, Percent_Identity=32.1243523316062, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787905, Length=198, Percent_Identity=30.3030303030303, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082160, Length=209, Percent_Identity=26.7942583732057, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790717, Length=194, Percent_Identity=25.2577319587629, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=193, Percent_Identity=36.2694300518135, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=197, Percent_Identity=32.994923857868, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI193203115, Length=197, Percent_Identity=28.9340101522843, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=195, Percent_Identity=28.7179487179487, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17567345, Length=204, Percent_Identity=28.4313725490196, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=203, Percent_Identity=30.0492610837438, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=206, Percent_Identity=29.126213592233, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=223, Percent_Identity=27.8026905829596, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=204, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=205, Percent_Identity=28.2926829268293, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=209, Percent_Identity=29.1866028708134, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=205, Percent_Identity=28.2926829268293, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=202, Percent_Identity=30.1980198019802, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=194, Percent_Identity=27.8350515463918, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=243, Percent_Identity=25.5144032921811, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21355319, Length=194, Percent_Identity=35.5670103092784, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24640492, Length=235, Percent_Identity=25.1063829787234, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281364494, Length=204, Percent_Identity=31.8627450980392, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=30.2083333333333, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI23397609, Length=229, Percent_Identity=30.1310043668122, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=30.2564102564103, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24581726, Length=202, Percent_Identity=27.2277227722772, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI221510726, Length=208, Percent_Identity=31.7307692307692, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24639444, Length=194, Percent_Identity=32.9896907216495, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281364892, Length=174, Percent_Identity=31.0344827586207, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358495, Length=261, Percent_Identity=26.4367816091954, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21357041, Length=201, Percent_Identity=29.8507462686567, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24663911, Length=204, Percent_Identity=27.4509803921569, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29829; Mature: 29829

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHLEGKTAFVTGAASGIGLGIATALAQAGVKVMLCDIEKAALDKAVATLRETNADVDGV
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCE
VADVSLKDNLQRAADETIARFGKVHILVNNAGVGGGGDYGTWNDAGWNWVVGVNLMSVVW
EEECCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHH
GIEIFGPLIEAHGEGGQIVSTASIAGMVALTNPAYDVTKFGVVALSEDLRPKLAARGIGV
HHHHHHHHHHCCCCCCCEEEHHHHHEEEEECCCCHHHHHHHHHEECHHHHHHHHHCCCCC
SVLCPGVIRTNIVDSGRNIPSRFAGQIQTVPTEGPGTEILKAVTEAIASGIDPLYVGELV
EEECCHHHHHHHHHCCCCCCHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
REAIENDWPHIFTDMQFEPHIEARFAAIKEGFDRIRDRVPRY
HHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKHLEGKTAFVTGAASGIGLGIATALAQAGVKVMLCDIEKAALDKAVATLRETNADVDGV
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCE
VADVSLKDNLQRAADETIARFGKVHILVNNAGVGGGGDYGTWNDAGWNWVVGVNLMSVVW
EEECCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHH
GIEIFGPLIEAHGEGGQIVSTASIAGMVALTNPAYDVTKFGVVALSEDLRPKLAARGIGV
HHHHHHHHHHCCCCCCCEEEHHHHHEEEEECCCCHHHHHHHHHEECHHHHHHHHHCCCCC
SVLCPGVIRTNIVDSGRNIPSRFAGQIQTVPTEGPGTEILKAVTEAIASGIDPLYVGELV
EEECCHHHHHHHHHCCCCCCHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
REAIENDWPHIFTDMQFEPHIEARFAAIKEGFDRIRDRVPRY
HHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1744051; 8495726; 7764263 [H]