Click here to switch to the map view.

The map label for this gene is codA [H]

Identifier: 114331704

GI number: 114331704

Start: 1818562

End: 1819749

Strand: Direct

Name: codA [H]

Synonym: Neut_1722

Alternate gene names: 114331704

Gene position: 1818562-1819749 (Clockwise)

Preceding gene: 114331703

Following gene: 114331705

Centisome position: 68.34

GC content: 47.14

Gene sequence:

>1188_bases
GTGATCAAGCAGATCGGAAAAAACCTGCCCAAGGCCGACGAGGAGATTGATCTTCAGGGTCGACTCGTAATCCCGCCCTA
TGTGGATGCCCATTTGCATTTGGATTATGTATACACTGGCAAAAACGATGGGGCCATGAACTCAAGCGGCACACTGTTTG
AAGGTATTGCACGCTGGCATGATGTGAAAAAAACTCAAACCTTCGAAGCGGCCAAGGAACGCGCGTTGAAAGGTATTAAT
GAAGAGGTCTCCAAGGGTGTCCAGTTTATCCGCACGCATATTGACGTAGATGACCCCAAGCTGACAGGTTTGAAAGCTAT
GCTGGAAATACGCGAGCAACTCAAAGACAGTATTACCATCCAGATTGTAGCTTTTCCGCAAGAAGGGATGTATGCCTATA
AGGGCGGCGAAGAAATGGTTGAAGAAGCGTTGAAAATGGGCGCAGACTGCGTCGGGGCCATCCCGCATTTCGAATGGGCG
CGCGAGATCGGCGAAAAATCCATCCACCGAACCGTAGAGTTAGCCGTTAAATATAACAAACTGATCGATGTTCACTGCGA
TGAAACCGATGATGTTATGAGCCGTTTTGTTGAGTTGCTCAACGCACTGGTGATGTCTGAAGGTATTGGCTCCCGCACAG
CGGCCAGCCATACTTGCTCTTTTGGCTCCGCAGATAATGCTTATGCTTTTCGTATGATGAGATTATTCCAAAAGTCAGGG
CTGAATTTCATCTCTTTACCAACCGAAAATGCTTATCTGCAAGGCCGACAAGATACCTACCCAAAGCGTCGTGGTCTCAC
CCGCGTGAAAGAATTATGGGAGAGCGGTATCAATGTCTGTTTTGGCCAGGATTCCATCAATGATCCTTGGTACCCGGTAG
GTAATGGAAATATGATGAATATCCTGGATAACGGTATTCATCTGGCACAGACAATGTCGTTCGATGAATTAGATCGATGC
CTCAATCTAATTACATCCAACGGTGCCAAAACGCTGAATGTTGAAGATCAGTATGGCATCGAGGTGGGTAAACCGGCTAA
CTTTATCGTCTTGAATGCAAAATCGCCATTTGAGGCCGTACGCCAACGGGCTGACGTATTGGCATCTATCCGCAACGGCG
AATATCTATTTAAGCGTCCTGAACCTCGCTACGAGGTTGAATTCGATGCCTTTGAAAAGATTAGCTAA

Upstream 100 bases:

>100_bases
GAAGAAGGTTACCCTCTTAAACTCGATACATTATTGTCTTGACGGAGGGGTCCACTATAGACAGCACGATGAAACAAGTG
AGATTTCAGTCGATAAAGGG

Downstream 100 bases:

>100_bases
ATAAATACTTGACAGAAAATCTAACTTGGCATTAAGAAATAATAAGTTGCGGATTTTTTCTGGAAGGGAGATTTTCTGAA
TTTAGTCGATGTGAAAGAGG

Product: N-isopropylammelide isopropylaminohydrolase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MIKQIGKNLPKADEEIDLQGRLVIPPYVDAHLHLDYVYTGKNDGAMNSSGTLFEGIARWHDVKKTQTFEAAKERALKGIN
EEVSKGVQFIRTHIDVDDPKLTGLKAMLEIREQLKDSITIQIVAFPQEGMYAYKGGEEMVEEALKMGADCVGAIPHFEWA
REIGEKSIHRTVELAVKYNKLIDVHCDETDDVMSRFVELLNALVMSEGIGSRTAASHTCSFGSADNAYAFRMMRLFQKSG
LNFISLPTENAYLQGRQDTYPKRRGLTRVKELWESGINVCFGQDSINDPWYPVGNGNMMNILDNGIHLAQTMSFDELDRC
LNLITSNGAKTLNVEDQYGIEVGKPANFIVLNAKSPFEAVRQRADVLASIRNGEYLFKRPEPRYEVEFDAFEKIS

Sequences:

>Translated_395_residues
MIKQIGKNLPKADEEIDLQGRLVIPPYVDAHLHLDYVYTGKNDGAMNSSGTLFEGIARWHDVKKTQTFEAAKERALKGIN
EEVSKGVQFIRTHIDVDDPKLTGLKAMLEIREQLKDSITIQIVAFPQEGMYAYKGGEEMVEEALKMGADCVGAIPHFEWA
REIGEKSIHRTVELAVKYNKLIDVHCDETDDVMSRFVELLNALVMSEGIGSRTAASHTCSFGSADNAYAFRMMRLFQKSG
LNFISLPTENAYLQGRQDTYPKRRGLTRVKELWESGINVCFGQDSINDPWYPVGNGNMMNILDNGIHLAQTMSFDELDRC
LNLITSNGAKTLNVEDQYGIEVGKPANFIVLNAKSPFEAVRQRADVLASIRNGEYLFKRPEPRYEVEFDAFEKIS
>Mature_395_residues
MIKQIGKNLPKADEEIDLQGRLVIPPYVDAHLHLDYVYTGKNDGAMNSSGTLFEGIARWHDVKKTQTFEAAKERALKGIN
EEVSKGVQFIRTHIDVDDPKLTGLKAMLEIREQLKDSITIQIVAFPQEGMYAYKGGEEMVEEALKMGADCVGAIPHFEWA
REIGEKSIHRTVELAVKYNKLIDVHCDETDDVMSRFVELLNALVMSEGIGSRTAASHTCSFGSADNAYAFRMMRLFQKSG
LNFISLPTENAYLQGRQDTYPKRRGLTRVKELWESGINVCFGQDSINDPWYPVGNGNMMNILDNGIHLAQTMSFDELDRC
LNLITSNGAKTLNVEDQYGIEVGKPANFIVLNAKSPFEAVRQRADVLASIRNGEYLFKRPEPRYEVEFDAFEKIS

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=386, Percent_Identity=48.9637305699482, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI1786517, Length=366, Percent_Identity=23.4972677595628, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 44473; Mature: 44473

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKQIGKNLPKADEEIDLQGRLVIPPYVDAHLHLDYVYTGKNDGAMNSSGTLFEGIARWH
CCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHH
DVKKTQTFEAAKERALKGINEEVSKGVQFIRTHIDVDDPKLTGLKAMLEIREQLKDSITI
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEE
QIVAFPQEGMYAYKGGEEMVEEALKMGADCVGAIPHFEWAREIGEKSIHRTVELAVKYNK
EEEEECCCCCEEECCCHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECC
LIDVHCDETDDVMSRFVELLNALVMSEGIGSRTAASHTCSFGSADNAYAFRMMRLFQKSG
EEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
LNFISLPTENAYLQGRQDTYPKRRGLTRVKELWESGINVCFGQDSINDPWYPVGNGNMMN
CCEEECCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCEECCCCCCHH
ILDNGIHLAQTMSFDELDRCLNLITSNGAKTLNVEDQYGIEVGKPANFIVLNAKSPFEAV
HHHCCHHHHHHCCHHHHHHHHHHHHCCCCEEECCCHHCCEEECCCCCEEEEECCCHHHHH
RQRADVLASIRNGEYLFKRPEPRYEVEFDAFEKIS
HHHHHHHHHHCCCCEEEECCCCCEEEECCHHHCCC
>Mature Secondary Structure
MIKQIGKNLPKADEEIDLQGRLVIPPYVDAHLHLDYVYTGKNDGAMNSSGTLFEGIARWH
CCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHH
DVKKTQTFEAAKERALKGINEEVSKGVQFIRTHIDVDDPKLTGLKAMLEIREQLKDSITI
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEE
QIVAFPQEGMYAYKGGEEMVEEALKMGADCVGAIPHFEWAREIGEKSIHRTVELAVKYNK
EEEEECCCCCEEECCCHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECC
LIDVHCDETDDVMSRFVELLNALVMSEGIGSRTAASHTCSFGSADNAYAFRMMRLFQKSG
EEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
LNFISLPTENAYLQGRQDTYPKRRGLTRVKELWESGINVCFGQDSINDPWYPVGNGNMMN
CCEEECCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCEECCCCCCHH
ILDNGIHLAQTMSFDELDRCLNLITSNGAKTLNVEDQYGIEVGKPANFIVLNAKSPFEAV
HHHCCHHHHHHCCHHHHHHHHHHHHCCCCEEECCCHHCCEEECCCCCEEEEECCCHHHHH
RQRADVLASIRNGEYLFKRPEPRYEVEFDAFEKIS
HHHHHHHHHHCCCCEEEECCCCCEEEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]