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The map label for this gene is speB [H]

Identifier: 114331426

GI number: 114331426

Start: 1517861

End: 1518829

Strand: Reverse

Name: speB [H]

Synonym: Neut_1437

Alternate gene names: 114331426

Gene position: 1518829-1517861 (Counterclockwise)

Preceding gene: 114331427

Following gene: 114331418

Centisome position: 57.08

GC content: 47.06

Gene sequence:

>969_bases
ATGTCGAACGGCCCTGTCAAAATTGATGGAGCAATAGTACGCAAAACACCTTATGGCATGCTGCGTGAACCGACCTTCTC
GGGCATACTTTCTTTTATGCGTTGCAGTTTTCGGAAAGACTTGACAGGTGCCGAGCTGGTGATCAGCGATATTCCACTGG
ATTTGGCGGTATCTTACCGTTCTGGCGCCCGGTTCGGACCACTGGGAATTCGCCAGGCTTCCGCTGAAGTGGCTTCGCTC
AAACCTTATCCATGGGGATTTGATCCATTCGAAAATCTTGCTGTGATCGATTTTGGAGACTGCTTTCTTGATGTACATAA
TCCAATGTCGATTCATGAGGCGATTATCGATCATGCCCGACATATTCTGGCATCTGGTGCGCGCATGTTGACGTTCGGTG
GTGATCACTCTATTTCTTATCCGTTGTTGAAAGCACATGTAGAGAAAACTGGCACTCCACTGTCTTTAATCCATTTTGAT
GCGCATTGTGATACCTGGCCAGATAATTCTCCAGCTTCACTGAATCATGGTTCCATGTTTTACAAAGCAGTGCAGGATGG
TTTGATTGATATCAAGCATTCGGTACAGATTGGTATTCGTACCTGGAATGATGATTTCATGGGGATTAATATTCTGGATG
CTGATCGAGTACATCGGGAGGGGACAGATGCAGTGGTTGCAGAAATTGAACGTATCGTCGGTAATCAGCCAGCCTATTTT
ACGTTTGATATCGATTGCCTTGATCCTGCTTATGCGCCGGGCACAGGCACACCGGTTTGTGGGGGGTTATCAACCGCACA
GGCGTTATCAATCATTCGCAGGCTTACTGCAATCAACCTGATTGGAATGGATATCGTAGAAGTATCTCCGCCCTATGATC
ACAGTCAGATAACCGCACTGGCTGCAGCACATATTGCTTGCGACTTGATTTGTCTGCTGGCAAAACGCAAAGCTGACGGG
CTGTTGTAA

Upstream 100 bases:

>100_bases
CAATGGTCTATCCTGCCTACTACCAGGATACCATCATGGCAGCGAGATTCTAACCACGTCATATAAGTACATTCAACGAT
AAAGGAAACAAAACCAGATC

Downstream 100 bases:

>100_bases
ATCCTGCTTGAATATGTGGACAGATTCATGTGTTCCGTACCAAACAGCAAGATCAGAATTTATATCCGCGATGCAGTGCT
ACAACGCCCGCTGTCAGATT

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MSNGPVKIDGAIVRKTPYGMLREPTFSGILSFMRCSFRKDLTGAELVISDIPLDLAVSYRSGARFGPLGIRQASAEVASL
KPYPWGFDPFENLAVIDFGDCFLDVHNPMSIHEAIIDHARHILASGARMLTFGGDHSISYPLLKAHVEKTGTPLSLIHFD
AHCDTWPDNSPASLNHGSMFYKAVQDGLIDIKHSVQIGIRTWNDDFMGINILDADRVHREGTDAVVAEIERIVGNQPAYF
TFDIDCLDPAYAPGTGTPVCGGLSTAQALSIIRRLTAINLIGMDIVEVSPPYDHSQITALAAAHIACDLICLLAKRKADG
LL

Sequences:

>Translated_322_residues
MSNGPVKIDGAIVRKTPYGMLREPTFSGILSFMRCSFRKDLTGAELVISDIPLDLAVSYRSGARFGPLGIRQASAEVASL
KPYPWGFDPFENLAVIDFGDCFLDVHNPMSIHEAIIDHARHILASGARMLTFGGDHSISYPLLKAHVEKTGTPLSLIHFD
AHCDTWPDNSPASLNHGSMFYKAVQDGLIDIKHSVQIGIRTWNDDFMGINILDADRVHREGTDAVVAEIERIVGNQPAYF
TFDIDCLDPAYAPGTGTPVCGGLSTAQALSIIRRLTAINLIGMDIVEVSPPYDHSQITALAAAHIACDLICLLAKRKADG
LL
>Mature_321_residues
SNGPVKIDGAIVRKTPYGMLREPTFSGILSFMRCSFRKDLTGAELVISDIPLDLAVSYRSGARFGPLGIRQASAEVASLK
PYPWGFDPFENLAVIDFGDCFLDVHNPMSIHEAIIDHARHILASGARMLTFGGDHSISYPLLKAHVEKTGTPLSLIHFDA
HCDTWPDNSPASLNHGSMFYKAVQDGLIDIKHSVQIGIRTWNDDFMGINILDADRVHREGTDAVVAEIERIVGNQPAYFT
FDIDCLDPAYAPGTGTPVCGGLSTAQALSIIRRLTAINLIGMDIVEVSPPYDHSQITALAAAHIACDLICLLAKRKADGL
L

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=296, Percent_Identity=40.8783783783784, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI10947139, Length=296, Percent_Identity=26.6891891891892, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4502215, Length=300, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1789306, Length=296, Percent_Identity=46.2837837837838, Blast_Score=257, Evalue=7e-70,
Organism=Drosophila melanogaster, GI24638886, Length=206, Percent_Identity=28.6407766990291, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 34982; Mature: 34851

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNGPVKIDGAIVRKTPYGMLREPTFSGILSFMRCSFRKDLTGAELVISDIPLDLAVSYR
CCCCCEEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEC
SGARFGPLGIRQASAEVASLKPYPWGFDPFENLAVIDFGDCFLDVHNPMSIHEAIIDHAR
CCCCCCCCCCHHHCCHHHHCCCCCCCCCCHHCEEEEEECCEEEECCCCHHHHHHHHHHHH
HILASGARMLTFGGDHSISYPLLKAHVEKTGTPLSLIHFDAHCDTWPDNSPASLNHGSMF
HHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCHHH
YKAVQDGLIDIKHSVQIGIRTWNDDFMGINILDADRVHREGTDAVVAEIERIVGNQPAYF
HHHHHCCCEEEEEEEEEEEEEECCCEEEEEEECHHHHHCCCCHHHHHHHHHHHCCCCCEE
TFDIDCLDPAYAPGTGTPVCGGLSTAQALSIIRRLTAINLIGMDIVEVSPPYDHSQITAL
EEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHH
AAAHIACDLICLLAKRKADGLL
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SNGPVKIDGAIVRKTPYGMLREPTFSGILSFMRCSFRKDLTGAELVISDIPLDLAVSYR
CCCCEEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEC
SGARFGPLGIRQASAEVASLKPYPWGFDPFENLAVIDFGDCFLDVHNPMSIHEAIIDHAR
CCCCCCCCCCHHHCCHHHHCCCCCCCCCCHHCEEEEEECCEEEECCCCHHHHHHHHHHHH
HILASGARMLTFGGDHSISYPLLKAHVEKTGTPLSLIHFDAHCDTWPDNSPASLNHGSMF
HHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCHHH
YKAVQDGLIDIKHSVQIGIRTWNDDFMGINILDADRVHREGTDAVVAEIERIVGNQPAYF
HHHHHCCCEEEEEEEEEEEEEECCCEEEEEEECHHHHHCCCCHHHHHHHHHHHCCCCCEE
TFDIDCLDPAYAPGTGTPVCGGLSTAQALSIIRRLTAINLIGMDIVEVSPPYDHSQITAL
EEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHH
AAAHIACDLICLLAKRKADGLL
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]