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The map label for this gene is apeB [H]

Identifier: 114331349

GI number: 114331349

Start: 1429207

End: 1430511

Strand: Reverse

Name: apeB [H]

Synonym: Neut_1358

Alternate gene names: 114331349

Gene position: 1430511-1429207 (Counterclockwise)

Preceding gene: 114331350

Following gene: 114331345

Centisome position: 53.76

GC content: 48.58

Gene sequence:

>1305_bases
ATGATAGCTCAAACGTATGTGCAGAATCTGCTGGATTTTATCGACAAAAGTCCAAGCCCATGGCATGCCGTTGCTTCGAT
CGAAGCAGAGATCGAAAAATTTCAATTCATCCGGCTTGATGAAACAGCCAGATGGCAGTTACATCCGGGCAGGCGCTACT
ATGTGGTGCGAGATGATTCCTCAATTATATTATTCGTACCGGGACAGACACCACCGGCAGAATCTGGATTCAGAATTATC
GGCGCACATACCGATTCTCCCGGATTGCGAATCAGACCCAATGCCGCAACTGCCAGTGATGGTATTGTCCGGTTGGGGGT
TGAAGTTTATGGCGGCCCCATTCTCGCCACTTTTGCTGATCGTGATCTAAGCCTGGCCGGGCGCGTCAGTTATTCCTACG
GGCAGGGACATCTTGCACATAAATTAGTGCGTATTGATCATCCTTTGCTGCGCATACCGAACCTGGCAATTCACATGAAC
CGGGGCGTCAATGAAGAAGGATTGAAGCTGCACAAACAGAATGAATTGTTGCCATTCCTTGCGCAATTGACCAACGATCA
ACTGCCGCAATCCTGTTTTTTGGCGCTGCTGGAACAGATGACAGGAATTGGTGCTTCACAAATCCTGTCCTGGGATTTGG
CTGTTTACGATACACAGAAAGGGGCATTCTGGGGGGCAAACCAGGAGTTTTATACCAATAGCCAGATTGATAATCTGGCG
TCCTGTCATGCCGGATTACAGGCAATGCTGGATGATACTGCGCTTAACCATGCCGCAAATACGTTTGTTTGCGCATTTTT
TGATCATGAAGAAATTGGCAGTGAAAGCCATATTGGTGCGGGCGGCAGTTTCTTGACAGATTTGTTACAGCGGATCAGCC
TGGCCACTTCTCCAGATCACGAAGATGCTGCGCGTGCACTAGCGCAGAGTTTTCTCATTAGTGCAGATATGGCACATGCC
TATCACCCCAACTTTCCCTCGGCTTATGATGCAGATCACAAGGTATCCGTGAACCAGGGGCCGGTAATCAAATTCAATGC
CAATCACCGCTATAGCTCAGAAAGTATTTCTGCCGCTCATTTCATTCACTGGTGTGAAGCAGCGGATGTACCTTATCAGC
GCTATTCACATCGCTCAGATTTACCTTGTGGCAGCACAATCGGGCCAATGACTTCAGCCAAACTGGGTATACGCAGTATT
GATATCGGTTGCCCGATGTGGGCCATGCACAGCATCCGGGAGAGCGCGGGCGTGCAGGATCACGAATATATGATCAAAGT
GTTGAAACAGTTTTTATTGAGTTAG

Upstream 100 bases:

>100_bases
CGTTTTGTCAGCTTCGATTCGCGCCTGAACCCGGACATTGTTTCAGGTGCAAGCCAACAACATATTGTAATTTTATAACT
TCCCTTTAAAAACAGAGATC

Downstream 100 bases:

>100_bases
CGTACCAGCCGCTCCTGATCAGGATGATCCGGCAAACAATCCGCCGGAGCGCTGGACCGTTCTGGAAACGGCTTGATCAA
TAATATTGCTGTTTCCGGTA

Product: putative aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MIAQTYVQNLLDFIDKSPSPWHAVASIEAEIEKFQFIRLDETARWQLHPGRRYYVVRDDSSIILFVPGQTPPAESGFRII
GAHTDSPGLRIRPNAATASDGIVRLGVEVYGGPILATFADRDLSLAGRVSYSYGQGHLAHKLVRIDHPLLRIPNLAIHMN
RGVNEEGLKLHKQNELLPFLAQLTNDQLPQSCFLALLEQMTGIGASQILSWDLAVYDTQKGAFWGANQEFYTNSQIDNLA
SCHAGLQAMLDDTALNHAANTFVCAFFDHEEIGSESHIGAGGSFLTDLLQRISLATSPDHEDAARALAQSFLISADMAHA
YHPNFPSAYDADHKVSVNQGPVIKFNANHRYSSESISAAHFIHWCEAADVPYQRYSHRSDLPCGSTIGPMTSAKLGIRSI
DIGCPMWAMHSIRESAGVQDHEYMIKVLKQFLLS

Sequences:

>Translated_434_residues
MIAQTYVQNLLDFIDKSPSPWHAVASIEAEIEKFQFIRLDETARWQLHPGRRYYVVRDDSSIILFVPGQTPPAESGFRII
GAHTDSPGLRIRPNAATASDGIVRLGVEVYGGPILATFADRDLSLAGRVSYSYGQGHLAHKLVRIDHPLLRIPNLAIHMN
RGVNEEGLKLHKQNELLPFLAQLTNDQLPQSCFLALLEQMTGIGASQILSWDLAVYDTQKGAFWGANQEFYTNSQIDNLA
SCHAGLQAMLDDTALNHAANTFVCAFFDHEEIGSESHIGAGGSFLTDLLQRISLATSPDHEDAARALAQSFLISADMAHA
YHPNFPSAYDADHKVSVNQGPVIKFNANHRYSSESISAAHFIHWCEAADVPYQRYSHRSDLPCGSTIGPMTSAKLGIRSI
DIGCPMWAMHSIRESAGVQDHEYMIKVLKQFLLS
>Mature_434_residues
MIAQTYVQNLLDFIDKSPSPWHAVASIEAEIEKFQFIRLDETARWQLHPGRRYYVVRDDSSIILFVPGQTPPAESGFRII
GAHTDSPGLRIRPNAATASDGIVRLGVEVYGGPILATFADRDLSLAGRVSYSYGQGHLAHKLVRIDHPLLRIPNLAIHMN
RGVNEEGLKLHKQNELLPFLAQLTNDQLPQSCFLALLEQMTGIGASQILSWDLAVYDTQKGAFWGANQEFYTNSQIDNLA
SCHAGLQAMLDDTALNHAANTFVCAFFDHEEIGSESHIGAGGSFLTDLLQRISLATSPDHEDAARALAQSFLISADMAHA
YHPNFPSAYDADHKVSVNQGPVIKFNANHRYSSESISAAHFIHWCEAADVPYQRYSHRSDLPCGSTIGPMTSAKLGIRSI
DIGCPMWAMHSIRESAGVQDHEYMIKVLKQFLLS

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=452, Percent_Identity=38.716814159292, Blast_Score=304, Evalue=9e-83,
Organism=Caenorhabditis elegans, GI17552916, Length=434, Percent_Identity=35.2534562211982, Blast_Score=265, Evalue=3e-71,
Organism=Saccharomyces cerevisiae, GI6321905, Length=463, Percent_Identity=36.2850971922246, Blast_Score=285, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6322746, Length=451, Percent_Identity=27.4944567627494, Blast_Score=186, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 47947; Mature: 47947

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAQTYVQNLLDFIDKSPSPWHAVASIEAEIEKFQFIRLDETARWQLHPGRRYYVVRDDS
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEECCCEEEEECCCCEEEEEECCC
SIILFVPGQTPPAESGFRIIGAHTDSPGLRIRPNAATASDGIVRLGVEVYGGPILATFAD
EEEEEECCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCCCEEEEEEEECCCEEEEEECC
RDLSLAGRVSYSYGQGHLAHKLVRIDHPLLRIPNLAIHMNRGVNEEGLKLHKQNELLPFL
CCCCEEEEEEECCCCCHHHHHHHHHCCCHHHCCCEEEEECCCCCHHHCEECCCCCHHHHH
AQLTNDQLPQSCFLALLEQMTGIGASQILSWDLAVYDTQKGAFWGANQEFYTNSQIDNLA
HHHHCCCCCHHHHHHHHHHHHCCCHHHHHEEEEEEEECCCCCEECCCCCEECCCCHHHHH
SCHAGLQAMLDDTALNHAANTFVCAFFDHEEIGSESHIGAGGSFLTDLLQRISLATSPDH
HHHHHHHHHHHHHHHHHCCCEEEEEEECHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCH
EDAARALAQSFLISADMAHAYHPNFPSAYDADHKVSVNQGPVIKFNANHRYSSESISAAH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCHHH
FIHWCEAADVPYQRYSHRSDLPCGSTIGPMTSAKLGIRSIDIGCPMWAMHSIRESAGVQD
HHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHCCCEEEECCCCHHHHHHHHHHCCCCH
HEYMIKVLKQFLLS
HHHHHHHHHHHHCC
>Mature Secondary Structure
MIAQTYVQNLLDFIDKSPSPWHAVASIEAEIEKFQFIRLDETARWQLHPGRRYYVVRDDS
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEECCCEEEEECCCCEEEEEECCC
SIILFVPGQTPPAESGFRIIGAHTDSPGLRIRPNAATASDGIVRLGVEVYGGPILATFAD
EEEEEECCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCCCEEEEEEEECCCEEEEEECC
RDLSLAGRVSYSYGQGHLAHKLVRIDHPLLRIPNLAIHMNRGVNEEGLKLHKQNELLPFL
CCCCEEEEEEECCCCCHHHHHHHHHCCCHHHCCCEEEEECCCCCHHHCEECCCCCHHHHH
AQLTNDQLPQSCFLALLEQMTGIGASQILSWDLAVYDTQKGAFWGANQEFYTNSQIDNLA
HHHHCCCCCHHHHHHHHHHHHCCCHHHHHEEEEEEEECCCCCEECCCCCEECCCCHHHHH
SCHAGLQAMLDDTALNHAANTFVCAFFDHEEIGSESHIGAGGSFLTDLLQRISLATSPDH
HHHHHHHHHHHHHHHHHCCCEEEEEEECHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCH
EDAARALAQSFLISADMAHAYHPNFPSAYDADHKVSVNQGPVIKFNANHRYSSESISAAH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCHHH
FIHWCEAADVPYQRYSHRSDLPCGSTIGPMTSAKLGIRSIDIGCPMWAMHSIRESAGVQD
HHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHCCCEEEECCCCHHHHHHHHHHCCCCH
HEYMIKVLKQFLLS
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA