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The map label for this gene is merR [H]

Identifier: 114331298

GI number: 114331298

Start: 1369597

End: 1370052

Strand: Reverse

Name: merR [H]

Synonym: Neut_1305

Alternate gene names: 114331298

Gene position: 1370052-1369597 (Counterclockwise)

Preceding gene: 114331308

Following gene: 114331296

Centisome position: 51.49

GC content: 60.96

Gene sequence:

>456_bases
ATGCAAATTAATTTTGAGAATCTGACCATTGGCGTTTTTGCCAAGGCGGCCGGGGTCAATGTGGAGACCATCCGGTTCTA
CCAGCGCAAGGGCCTGCTGCCGGAGCCAGACAAGCCCTATGGCAGCATTCGCCGCTATGGCGAGGCGGATGTAACACGAG
TGCGGTTCGTGAAATCGGCCCAGCGGCTGGGCTTTAGCCTGGACGAAATCGCCGAGCTACTGCGGCTGGAGGATGGCACC
CATTGCGAGGAAGCCAGCGGCCTGGCCGAGCACAAGCTCAAGGATGTGCGCGAGAAGATGGCCGACTTGGCACGCATGGA
GGCCGTGCTGTCTGAACTGGTGTGCGCCTGCCATGCGCGGAAAGGGAACGTTTCCTGCCCGCTGATTGCGTCACTGCAAG
ACGGAACGAAGCTCGCTGCATCGGCGCGGGGGAGTCACGGGGTGACTACGCCTTAG

Upstream 100 bases:

>100_bases
GCGCCGCGCCCGTTTTGTGGTTCAGACATACGCTTGTCCTTTCAAATTTGGTTTGGATAGCTTAAGCTTACTTCCGTAGT
TATGTACGGAGTCAAGCGAT

Downstream 100 bases:

>100_bases
CGTGCTTTATTTTCCGAATTCTGAGACGACCCCATATTGGAAGATTATCCATTGTCCTTACTGACTGCATTAATCAGCAC
CTCTCCATCTATAAACTGCC

Product: putative transcriptional regulator MerR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MQINFENLTIGVFAKAAGVNVETIRFYQRKGLLPEPDKPYGSIRRYGEADVTRVRFVKSAQRLGFSLDEIAELLRLEDGT
HCEEASGLAEHKLKDVREKMADLARMEAVLSELVCACHARKGNVSCPLIASLQDGTKLAASARGSHGVTTP

Sequences:

>Translated_151_residues
MQINFENLTIGVFAKAAGVNVETIRFYQRKGLLPEPDKPYGSIRRYGEADVTRVRFVKSAQRLGFSLDEIAELLRLEDGT
HCEEASGLAEHKLKDVREKMADLARMEAVLSELVCACHARKGNVSCPLIASLQDGTKLAASARGSHGVTTP
>Mature_151_residues
MQINFENLTIGVFAKAAGVNVETIRFYQRKGLLPEPDKPYGSIRRYGEADVTRVRFVKSAQRLGFSLDEIAELLRLEDGT
HCEEASGLAEHKLKDVREKMADLARMEAVLSELVCACHARKGNVSCPLIASLQDGTKLAASARGSHGVTTP

Specific function: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury merR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a pote

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=130, Percent_Identity=34.6153846153846, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011794
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16529; Mature: 16529

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQINFENLTIGVFAKAAGVNVETIRFYQRKGLLPEPDKPYGSIRRYGEADVTRVRFVKSA
CCCCCCCEEEEEEHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHH
QRLGFSLDEIAELLRLEDGTHCEEASGLAEHKLKDVREKMADLARMEAVLSELVCACHAR
HHHCCCHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KGNVSCPLIASLQDGTKLAASARGSHGVTTP
CCCCCCCEEECCCCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQINFENLTIGVFAKAAGVNVETIRFYQRKGLLPEPDKPYGSIRRYGEADVTRVRFVKSA
CCCCCCCEEEEEEHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHH
QRLGFSLDEIAELLRLEDGTHCEEASGLAEHKLKDVREKMADLARMEAVLSELVCACHAR
HHHCCCHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KGNVSCPLIASLQDGTKLAASARGSHGVTTP
CCCCCCCEEECCCCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6091128; 2551364 [H]