Click here to switch to the map view.

The map label for this gene is menB [H]

Identifier: 113477508

GI number: 113477508

Start: 6306413

End: 6307276

Strand: Reverse

Name: menB [H]

Synonym: Tery_4088

Alternate gene names: 113477508

Gene position: 6307276-6306413 (Counterclockwise)

Preceding gene: 113477512

Following gene: 113477504

Centisome position: 81.38

GC content: 40.39

Gene sequence:

>864_bases
ATGAATATTAGATATATGAGTAATCAGCTTTCACAAGTAGAATGGCAAGTTGTTAAAGAGTATAACGATATTCTTTACCA
CAAAACTGATGGAATTGCCAAAATAACTATTAATCGTCCTCACAAACGTAATGCCTTTCGCCCTAAAACTGTATTTGAAC
TTTATGATGCTTTTGTTGACGCTCGTGAAGACCCTAATATTGGAGTGGTTTTGTTGACAGGTGCGGGACCCCATAAAGAC
GGTAAATATGCTTTCTGTTCTGGTGGAGACCAAAGTGTACGAGGTACAGCAGGTTATGTAGATGAGGCCGGAGTGCCACG
GTTGAATGTCTTGGACTTACAACGGTTAATTCGTTCCATGCCTAAAGTTGTCATAGCTTTAGTAGCTGGATATGCTATTG
GTGGAGGCCATGTTTTGCATATTATTTGTGACCTAACTATTGCCGCAGATAATGCAATTTTTGGTCAAACTGGCCCCAAG
GTAGGTAGTTTTGATGGAGGCTTTGGGGCTAGTTATTTAGCAAGAATTGTTGGTCAGAAAAAAGCACGAGAAATTTGGTT
TCTCTGTCGGCAATACACAGCTGAACAAGCTTTAGACATGGGTTTGGTTAATTGTGTTGTACCAGTAGAGGAGTTAGAAA
CAGAAGGTATTAAGTGGGCATTTGAAATTTTGGCAAAAAGCCCGATCGCTATTCGTTGTCTCAAAGCAGCTTTTAATGCT
GATTGTGATGGACAAGCTGGTCTACAAGAATTGGCAGGTAATGCTACTCTTCTTTATTACATGACAGAGGAAGGAGCTGA
AGGTAAAAAGGCGTTTTTAGAAAAACGGTCTCCAGACTTTCGTAAATATCCTTGGCTACCGTGA

Upstream 100 bases:

>100_bases
AATGATATAGAGGTTTAACAAATGCTTTCCGTGCACTGACCCCCATTAAACCGTAGCCTATTTAGAGAAGTTTTTTGGGT
TATATTTGTTGAGCAACATT

Downstream 100 bases:

>100_bases
CCTTTGTGCCACTTGTCTAGCATTTTTCATTAACAGCAAATTGCTTATAAAGCCTCGTCTCTTCGGGGCGACTTTTATTT
AATTTTGCTCTGATAAAAAT

Product: naphthoate synthase

Products: NA

Alternate protein names: DHNA-CoA synthase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MNIRYMSNQLSQVEWQVVKEYNDILYHKTDGIAKITINRPHKRNAFRPKTVFELYDAFVDAREDPNIGVVLLTGAGPHKD
GKYAFCSGGDQSVRGTAGYVDEAGVPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHIICDLTIAADNAIFGQTGPK
VGSFDGGFGASYLARIVGQKKAREIWFLCRQYTAEQALDMGLVNCVVPVEELETEGIKWAFEILAKSPIAIRCLKAAFNA
DCDGQAGLQELAGNATLLYYMTEEGAEGKKAFLEKRSPDFRKYPWLP

Sequences:

>Translated_287_residues
MNIRYMSNQLSQVEWQVVKEYNDILYHKTDGIAKITINRPHKRNAFRPKTVFELYDAFVDAREDPNIGVVLLTGAGPHKD
GKYAFCSGGDQSVRGTAGYVDEAGVPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHIICDLTIAADNAIFGQTGPK
VGSFDGGFGASYLARIVGQKKAREIWFLCRQYTAEQALDMGLVNCVVPVEELETEGIKWAFEILAKSPIAIRCLKAAFNA
DCDGQAGLQELAGNATLLYYMTEEGAEGKKAFLEKRSPDFRKYPWLP
>Mature_287_residues
MNIRYMSNQLSQVEWQVVKEYNDILYHKTDGIAKITINRPHKRNAFRPKTVFELYDAFVDAREDPNIGVVLLTGAGPHKD
GKYAFCSGGDQSVRGTAGYVDEAGVPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHIICDLTIAADNAIFGQTGPK
VGSFDGGFGASYLARIVGQKKAREIWFLCRQYTAEQALDMGLVNCVVPVEELETEGIKWAFEILAKSPIAIRCLKAAFNA
DCDGQAGLQELAGNATLLYYMTEEGAEGKKAFLEKRSPDFRKYPWLP

Specific function: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) [H]

COG id: COG0447

COG function: function code H; Dihydroxynaphthoic acid synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=257, Percent_Identity=32.295719844358, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI31542718, Length=268, Percent_Identity=29.4776119402985, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI4502327, Length=268, Percent_Identity=29.1044776119403, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788597, Length=278, Percent_Identity=70.5035971223022, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1787659, Length=263, Percent_Identity=30.0380228136882, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI221142681, Length=265, Percent_Identity=32.0754716981132, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082183, Length=263, Percent_Identity=29.6577946768061, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787660, Length=272, Percent_Identity=31.6176470588235, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788682, Length=209, Percent_Identity=27.7511961722488, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=253, Percent_Identity=30.4347826086957, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17554946, Length=252, Percent_Identity=29.7619047619048, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17540714, Length=218, Percent_Identity=30.2752293577982, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17549921, Length=214, Percent_Identity=30.3738317757009, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=293, Percent_Identity=28.6689419795222, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17535521, Length=214, Percent_Identity=27.1028037383178, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=212, Percent_Identity=28.7735849056604, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536985, Length=224, Percent_Identity=25.8928571428571, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20129971, Length=269, Percent_Identity=31.2267657992565, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24653477, Length=269, Percent_Identity=31.2267657992565, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24653139, Length=273, Percent_Identity=29.6703296703297, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI19922422, Length=291, Percent_Identity=27.4914089347079, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357171, Length=191, Percent_Identity=30.8900523560209, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24650670, Length=217, Percent_Identity=27.6497695852535, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24654903, Length=197, Percent_Identity=25.8883248730964, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376
- InterPro:   IPR010198 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.1.3.36 [H]

Molecular weight: Translated: 31651; Mature: 31651

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRYMSNQLSQVEWQVVKEYNDILYHKTDGIAKITINRPHKRNAFRPKTVFELYDAFVD
CCCCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHC
AREDPNIGVVLLTGAGPHKDGKYAFCSGGDQSVRGTAGYVDEAGVPRLNVLDLQRLIRSM
CCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
PKVVIALVAGYAIGGGHVLHIICDLTIAADNAIFGQTGPKVGSFDGGFGASYLARIVGQK
HHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCEECCCCCCCCCCCCCCHHHHHHHHHCCH
KAREIWFLCRQYTAEQALDMGLVNCVVPVEELETEGIKWAFEILAKSPIAIRCLKAAFNA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCC
DCDGQAGLQELAGNATLLYYMTEEGAEGKKAFLEKRSPDFRKYPWLP
CCCCCHHHHHHCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNIRYMSNQLSQVEWQVVKEYNDILYHKTDGIAKITINRPHKRNAFRPKTVFELYDAFVD
CCCCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHC
AREDPNIGVVLLTGAGPHKDGKYAFCSGGDQSVRGTAGYVDEAGVPRLNVLDLQRLIRSM
CCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
PKVVIALVAGYAIGGGHVLHIICDLTIAADNAIFGQTGPKVGSFDGGFGASYLARIVGQK
HHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCEECCCCCCCCCCCCCCHHHHHHHHHCCH
KAREIWFLCRQYTAEQALDMGLVNCVVPVEELETEGIKWAFEILAKSPIAIRCLKAAFNA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCC
DCDGQAGLQELAGNATLLYYMTEEGAEGKKAFLEKRSPDFRKYPWLP
CCCCCHHHHHHCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]