Click here to switch to the map view.

The map label for this gene is menC [H]

Identifier: 113477491

GI number: 113477491

Start: 6281793

End: 6282737

Strand: Reverse

Name: menC [H]

Synonym: Tery_4068

Alternate gene names: 113477491

Gene position: 6282737-6281793 (Counterclockwise)

Preceding gene: 113477492

Following gene: 113477490

Centisome position: 81.07

GC content: 32.06

Gene sequence:

>945_bases
ATGCATTATAAACTAAAAATTTTTCCCTATAAACGGAACTTCAAACAACCTTTAAAAACAAGTCATGGTATTTGGCGTAT
TAGAGAAGGAATAATTTTAAAACTAACCAATAAAACTGGAGAAATAGGTTTAGGTGAAATTGCACCTTTAAGTTTTTTTG
GTTCGGAAACTTTGTCGGAAGCTTTAGATTTTTGTCACCAGTTACCACCAAAAATTACAACAGAAACTATTTTTTCTATT
CCCGATAATTTACCTAGTTGTAAATTTGGCTTTGAGTCAGCTTGGGAAAATTTTCAAGAAGTACAAGTACAGGAAAAAGA
AGAATTAAACCCGAAATTTTACAGTGCTCTATTACCAGCAGGAAAAGCAGCTTTAGAAACTTGGCAGCAACTTTGGCAAA
AAGGATACCGCACTTTCAAATGGAAAATTGGACTTGATCAAATTCAAACAGAAATAAAGATATTTCAGCAGTTAGTTAAA
GAACTCCCTACCGGAATAAATTTAAGATTGGATGCCAATGGAGGATTAAATTTTGAAGAAGCAAAACAATGGTTAGAAAT
ATGCGAAAATATCAATATAATTGAGTTACTTGAGCAACCTTTACCTGTTGATAAATTTATCGAAATGTTGGATTTAAGTA
ATTTCTATTCTACCCCTATTGCCTTAGATGAATCTGTTGCTAACCTCAGCAAAATGCAACAATATTATCAACAAGGTTGG
CAAGGAATATTCGTAATTAAACCTGCTATTTTTGGTTCCCGTATTGATCTCTGTAACTTTTGTCAAAATTATCTCATTGA
TGCAGTTTTTTCTTCAGTATTTGAAACAAAAATTGCTAGAAAAGCATCATTGCAGCTTGCCACAAAATTACAACCAAACT
TAAGAAAAAACCGTGCTTTTGGTTTTGGTATCACCCACTTTTTTGATGCAGATATAGAAAATTAA

Upstream 100 bases:

>100_bases
TAAAAGTTATATTTGCACAACATGACCCAGGAAAAGCCAAATACTTACCAATAAAAATGTAAGAAAGTTAAGTTTTTCCA
GAAAATCTTACAAAAAAAAT

Downstream 100 bases:

>100_bases
GCCAAAACTCAAAAATTTATGTCTTTATCTGCGGGAGGGAGTCAAAATTTATCTATATATTTTTCAGAAATGAAATATTT
TAGTTACCAGCTAATTTGAC

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MHYKLKIFPYKRNFKQPLKTSHGIWRIREGIILKLTNKTGEIGLGEIAPLSFFGSETLSEALDFCHQLPPKITTETIFSI
PDNLPSCKFGFESAWENFQEVQVQEKEELNPKFYSALLPAGKAALETWQQLWQKGYRTFKWKIGLDQIQTEIKIFQQLVK
ELPTGINLRLDANGGLNFEEAKQWLEICENINIIELLEQPLPVDKFIEMLDLSNFYSTPIALDESVANLSKMQQYYQQGW
QGIFVIKPAIFGSRIDLCNFCQNYLIDAVFSSVFETKIARKASLQLATKLQPNLRKNRAFGFGITHFFDADIEN

Sequences:

>Translated_314_residues
MHYKLKIFPYKRNFKQPLKTSHGIWRIREGIILKLTNKTGEIGLGEIAPLSFFGSETLSEALDFCHQLPPKITTETIFSI
PDNLPSCKFGFESAWENFQEVQVQEKEELNPKFYSALLPAGKAALETWQQLWQKGYRTFKWKIGLDQIQTEIKIFQQLVK
ELPTGINLRLDANGGLNFEEAKQWLEICENINIIELLEQPLPVDKFIEMLDLSNFYSTPIALDESVANLSKMQQYYQQGW
QGIFVIKPAIFGSRIDLCNFCQNYLIDAVFSSVFETKIARKASLQLATKLQPNLRKNRAFGFGITHFFDADIEN
>Mature_314_residues
MHYKLKIFPYKRNFKQPLKTSHGIWRIREGIILKLTNKTGEIGLGEIAPLSFFGSETLSEALDFCHQLPPKITTETIFSI
PDNLPSCKFGFESAWENFQEVQVQEKEELNPKFYSALLPAGKAALETWQQLWQKGYRTFKWKIGLDQIQTEIKIFQQLVK
ELPTGINLRLDANGGLNFEEAKQWLEICENINIIELLEQPLPVDKFIEMLDLSNFYSTPIALDESVANLSKMQQYYQQGW
QGIFVIKPAIFGSRIDLCNFCQNYLIDAVFSSVFETKIARKASLQLATKLQPNLRKNRAFGFGITHFFDADIEN

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR001354
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 36188; Mature: 36188

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYKLKIFPYKRNFKQPLKTSHGIWRIREGIILKLTNKTGEIGLGEIAPLSFFGSETLSE
CCEEEEEEECCCCHHHHHHHCCCHHEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
ALDFCHQLPPKITTETIFSIPDNLPSCKFGFESAWENFQEVQVQEKEELNPKFYSALLPA
HHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
GKAALETWQQLWQKGYRTFKWKIGLDQIQTEIKIFQQLVKELPTGINLRLDANGGLNFEE
CHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
AKQWLEICENINIIELLEQPLPVDKFIEMLDLSNFYSTPIALDESVANLSKMQQYYQQGW
HHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
QGIFVIKPAIFGSRIDLCNFCQNYLIDAVFSSVFETKIARKASLQLATKLQPNLRKNRAF
CEEEEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
GFGITHFFDADIEN
CCCHHHHCCCCCCC
>Mature Secondary Structure
MHYKLKIFPYKRNFKQPLKTSHGIWRIREGIILKLTNKTGEIGLGEIAPLSFFGSETLSE
CCEEEEEEECCCCHHHHHHHCCCHHEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
ALDFCHQLPPKITTETIFSIPDNLPSCKFGFESAWENFQEVQVQEKEELNPKFYSALLPA
HHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
GKAALETWQQLWQKGYRTFKWKIGLDQIQTEIKIFQQLVKELPTGINLRLDANGGLNFEE
CHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
AKQWLEICENINIIELLEQPLPVDKFIEMLDLSNFYSTPIALDESVANLSKMQQYYQQGW
HHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
QGIFVIKPAIFGSRIDLCNFCQNYLIDAVFSSVFETKIARKASLQLATKLQPNLRKNRAF
CEEEEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
GFGITHFFDADIEN
CCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]