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The map label for this gene is mutT [H]

Identifier: 113477480

GI number: 113477480

Start: 6264531

End: 6264926

Strand: Reverse

Name: mutT [H]

Synonym: Tery_4056

Alternate gene names: 113477480

Gene position: 6264926-6264531 (Counterclockwise)

Preceding gene: 113477481

Following gene: 113477478

Centisome position: 80.84

GC content: 33.08

Gene sequence:

>396_bases
ATGGCATTATCTAATAAGTTAATTGGCGTTGCTGTCATCTGGGATGAAACAGGAAAAATATTAATTGATAAACGAAGATT
AGGGGATTCGTTTGGTGGTTTATGGGAATTTCCTGGAGGTAAAAAAGAAGCTGGTGAAACAATAGAAAATTGTATTAAAA
GGGAAGTTTTAGAGGAGTTGGGAATTGAGGTTGCAGTAGAAAAGCATTTAATTACAATAGAGTATAATTATTCTGAAATT
AGACTCATCCTTCATGTATATCATTGTCGTTACTTGCGGGGAATACCAAAAGCTATAGAATGTGATGAGTTTAGGTGGGT
AACATTAGATGAGATAGATAGATTTACTTTTCCTGAAGCTAATGAGCAAATTATTACTGCTTTGAAGAAAATATGA

Upstream 100 bases:

>100_bases
TAAGTTTGGGTAATTTTAGTAGAACGGTTAATTAGTCAATTTTTAATCATTCCCTTGGTTGCTAGACTAAGGGTTTTTTT
TATTAGAAATAAGAATTAAT

Downstream 100 bases:

>100_bases
ATCTAAGTAGATTGATTTTGAATATACTGTTTCCAGACTTTATTTAAACTAAAATAAGTTGTCTGATATTCTTGTTTTAT
ATCTAATAATAATCGTCTTT

Product: mutator MutT protein

Products: NA

Alternate protein names: 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase [H]

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MALSNKLIGVAVIWDETGKILIDKRRLGDSFGGLWEFPGGKKEAGETIENCIKREVLEELGIEVAVEKHLITIEYNYSEI
RLILHVYHCRYLRGIPKAIECDEFRWVTLDEIDRFTFPEANEQIITALKKI

Sequences:

>Translated_131_residues
MALSNKLIGVAVIWDETGKILIDKRRLGDSFGGLWEFPGGKKEAGETIENCIKREVLEELGIEVAVEKHLITIEYNYSEI
RLILHVYHCRYLRGIPKAIECDEFRWVTLDEIDRFTFPEANEQIITALKKI
>Mature_130_residues
ALSNKLIGVAVIWDETGKILIDKRRLGDSFGGLWEFPGGKKEAGETIENCIKREVLEELGIEVAVEKHLITIEYNYSEIR
LILHVYHCRYLRGIPKAIECDEFRWVTLDEIDRFTFPEANEQIITALKKI

Specific function: Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus lea

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786288, Length=124, Percent_Identity=32.258064516129, Blast_Score=67, Evalue=5e-13,
Organism=Escherichia coli, GI1788056, Length=122, Percent_Identity=31.1475409836066, Blast_Score=64, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.2.2.-

Molecular weight: Translated: 15135; Mature: 15004

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSNKLIGVAVIWDETGKILIDKRRLGDSFGGLWEFPGGKKEAGETIENCIKREVLEEL
CCCCCCEEEEEEEECCCCCEEEEHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHC
GIEVAVEKHLITIEYNYSEIRLILHVYHCRYLRGIPKAIECDEFRWVTLDEIDRFTFPEA
CCEEEEEEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHCCCCCCCC
NEQIITALKKI
CHHHHHHHHCC
>Mature Secondary Structure 
ALSNKLIGVAVIWDETGKILIDKRRLGDSFGGLWEFPGGKKEAGETIENCIKREVLEEL
CCCCCEEEEEEEECCCCCEEEEHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHC
GIEVAVEKHLITIEYNYSEIRLILHVYHCRYLRGIPKAIECDEFRWVTLDEIDRFTFPEA
CCEEEEEEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHCCCCCCCC
NEQIITALKKI
CHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]