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The map label for this gene is nusA [H]

Identifier: 113477415

GI number: 113477415

Start: 6152058

End: 6153338

Strand: Reverse

Name: nusA [H]

Synonym: Tery_3978

Alternate gene names: 113477415

Gene position: 6153338-6152058 (Counterclockwise)

Preceding gene: 113477416

Following gene: 113477414

Centisome position: 79.4

GC content: 37.55

Gene sequence:

>1281_bases
ATGTCAATGGTTAGTTTGCCTGGACTTAAAGAGTTAATCGGAAATATTAGTAAAGAACGTAATTTACCAAAACAAGCAGT
TCAGACTGCTTTACGAGAAGCTCTATTAAAAGGATATGAACGCTACAGACGAACTCAACGTGTAGATGGAGTCAACTTCA
CAGATGATTACTTCGAAAATTTTGAAATAGAACTGGATATTGAAGAAGAAGGTTATCGAGTATTAGCTACAAAAACTATT
GTTGAAGAAGTAACAAATCCAGATCATCATATAGCTCTCCAAGAAGTTTTAGAAGTAGCCTCAGAAGCTCAGTTAAATGA
TACAGTATTCTTGGATGTGACACCCGAAAAAAATGAATTTGGTCGCATGGCTGCTATACAGACTAAACAAGTATTAGCTC
AAAAGCTACGAGATCAACAACGAAAAATGATTCAAGAAGAATTTCAAGATTTAGAAGGAGAAGTTCTCCAAGCCAGAGTT
TTGAGATTTGAAAAACAGTCAGTTATCTTAGCTGTAAGTAGTGGATTTGGTAGACTAGAAGTAGAAGCTGAACTGCCTAA
AAAAGAACAACTACCTAATGATAACTACCGTGCTAATGCTACTTTTAAAGTCTATTTGAAGCGAGTTTGTGAAGGGTCAA
CTCGTGGGCCTCAATTACTTGTGTCTAGAGCTGATGCCGGCTTAGTGGTTTATTTATTTGAAAATGAAGTCCCAGAAATT
GAAGATGAAGTCGTAAGAATTGTGGCAGTTGCTAGAGAGGCAAATCCCCCATCTCGGCATGTTGGTCCCAGAACTAAAAT
AGCAGTTGATACTTTAGAAAGGGATGTAGATCCAGTGGGAGCTTGCATTGGTGCAAGGGGCTCAAGAATTCAGGTAGTTG
TGAATGAGTTGAGAGGTGAAAAAATAGATGTAATTCGCTGGTCTCCAGACCCTTCTATATATATAGCTAATTCTCTTAGT
CCAGCTAGAGTAGATGAAGTTCGTTTAATTGATCCAGAGGAAAGGAGGTCTCATATTTTGGTGTCTGAAGACCAACTTAG
TTTGGCTATCGGCAAGGAAGGACAAAATGTGCGTTTAGCTGCTCGTTTGACAGGGTGGAAAATTGATATTAAGGACACAA
ATAGATATGACCATGCTGAAGAAGATAGCAAAGTTGCGGCTGAAGTCTCTCATCGTCAAGCGTTAGCTGAACAAGAAGAA
AATAAAATTGAGGAATCAGAATTAGAAGTAATAGAAAATACTTTCGACAAAAATTTTAATGAACCAGATGATTCTTTTTA
A

Upstream 100 bases:

>100_bases
ATCTAGAGTAACCCAGATTATTAATGCCCTAATATCACCAAGATTTAAATAAATTAGCCTCAATAACAATAATTCATAAC
AATTTAGAGGATAAAAAAAT

Downstream 100 bases:

>100_bases
TTCAAATTACAATTAATCTAATTAATTTTATCTCCTCGCATTTGATGAAATAATTAACATTTATTACTCAGAGAAGATTT
TCTTAATTAAGAACAACTTT

Product: transcription elongation factor NusA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSMVSLPGLKELIGNISKERNLPKQAVQTALREALLKGYERYRRTQRVDGVNFTDDYFENFEIELDIEEEGYRVLATKTI
VEEVTNPDHHIALQEVLEVASEAQLNDTVFLDVTPEKNEFGRMAAIQTKQVLAQKLRDQQRKMIQEEFQDLEGEVLQARV
LRFEKQSVILAVSSGFGRLEVEAELPKKEQLPNDNYRANATFKVYLKRVCEGSTRGPQLLVSRADAGLVVYLFENEVPEI
EDEVVRIVAVAREANPPSRHVGPRTKIAVDTLERDVDPVGACIGARGSRIQVVVNELRGEKIDVIRWSPDPSIYIANSLS
PARVDEVRLIDPEERRSHILVSEDQLSLAIGKEGQNVRLAARLTGWKIDIKDTNRYDHAEEDSKVAAEVSHRQALAEQEE
NKIEESELEVIENTFDKNFNEPDDSF

Sequences:

>Translated_426_residues
MSMVSLPGLKELIGNISKERNLPKQAVQTALREALLKGYERYRRTQRVDGVNFTDDYFENFEIELDIEEEGYRVLATKTI
VEEVTNPDHHIALQEVLEVASEAQLNDTVFLDVTPEKNEFGRMAAIQTKQVLAQKLRDQQRKMIQEEFQDLEGEVLQARV
LRFEKQSVILAVSSGFGRLEVEAELPKKEQLPNDNYRANATFKVYLKRVCEGSTRGPQLLVSRADAGLVVYLFENEVPEI
EDEVVRIVAVAREANPPSRHVGPRTKIAVDTLERDVDPVGACIGARGSRIQVVVNELRGEKIDVIRWSPDPSIYIANSLS
PARVDEVRLIDPEERRSHILVSEDQLSLAIGKEGQNVRLAARLTGWKIDIKDTNRYDHAEEDSKVAAEVSHRQALAEQEE
NKIEESELEVIENTFDKNFNEPDDSF
>Mature_425_residues
SMVSLPGLKELIGNISKERNLPKQAVQTALREALLKGYERYRRTQRVDGVNFTDDYFENFEIELDIEEEGYRVLATKTIV
EEVTNPDHHIALQEVLEVASEAQLNDTVFLDVTPEKNEFGRMAAIQTKQVLAQKLRDQQRKMIQEEFQDLEGEVLQARVL
RFEKQSVILAVSSGFGRLEVEAELPKKEQLPNDNYRANATFKVYLKRVCEGSTRGPQLLVSRADAGLVVYLFENEVPEIE
DEVVRIVAVAREANPPSRHVGPRTKIAVDTLERDVDPVGACIGARGSRIQVVVNELRGEKIDVIRWSPDPSIYIANSLSP
ARVDEVRLIDPEERRSHILVSEDQLSLAIGKEGQNVRLAARLTGWKIDIKDTNRYDHAEEDSKVAAEVSHRQALAEQEEN
KIEESELEVIENTFDKNFNEPDDSF

Specific function: Participates in both the termination and antitermination of transcription. Interacts with RNA polymerase and binds RNA [H]

COG id: COG0195

COG function: function code K; Transcription elongation factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI1789560, Length=355, Percent_Identity=31.5492957746479, Blast_Score=181, Evalue=6e-47,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1612 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004087
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004088
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013735
- InterPro:   IPR010213 [H]

Pfam domain/function: PF08529 NusA_N; PF00575 S1 [H]

EC number: NA

Molecular weight: Translated: 48344; Mature: 48213

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMVSLPGLKELIGNISKERNLPKQAVQTALREALLKGYERYRRTQRVDGVNFTDDYFEN
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCC
FEIELDIEEEGYRVLATKTIVEEVTNPDHHIALQEVLEVASEAQLNDTVFLDVTPEKNEF
EEEEEEECCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
GRMAAIQTKQVLAQKLRDQQRKMIQEEFQDLEGEVLQARVLRFEKQSVILAVSSGFGRLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEE
VEAELPKKEQLPNDNYRANATFKVYLKRVCEGSTRGPQLLVSRADAGLVVYLFENEVPEI
EEECCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCH
EDEVVRIVAVAREANPPSRHVGPRTKIAVDTLERDVDPVGACIGARGSRIQVVVNELRGE
HHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHCCCCHHHHHHCCCCCEEEEEHHHHCCC
KIDVIRWSPDPSIYIANSLSPARVDEVRLIDPEERRSHILVSEDQLSLAIGKEGQNVRLA
EEEEEEECCCCCEEEECCCCCCCCCCEEEECCHHHCCEEEEECCCEEEEECCCCCCEEEE
ARLTGWKIDIKDTNRYDHAEEDSKVAAEVSHRQALAEQEENKIEESELEVIENTFDKNFN
EEEECEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
EPDDSF
CCCCCC
>Mature Secondary Structure 
SMVSLPGLKELIGNISKERNLPKQAVQTALREALLKGYERYRRTQRVDGVNFTDDYFEN
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCC
FEIELDIEEEGYRVLATKTIVEEVTNPDHHIALQEVLEVASEAQLNDTVFLDVTPEKNEF
EEEEEEECCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
GRMAAIQTKQVLAQKLRDQQRKMIQEEFQDLEGEVLQARVLRFEKQSVILAVSSGFGRLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEE
VEAELPKKEQLPNDNYRANATFKVYLKRVCEGSTRGPQLLVSRADAGLVVYLFENEVPEI
EEECCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCH
EDEVVRIVAVAREANPPSRHVGPRTKIAVDTLERDVDPVGACIGARGSRIQVVVNELRGE
HHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHCCCCHHHHHHCCCCCEEEEEHHHHCCC
KIDVIRWSPDPSIYIANSLSPARVDEVRLIDPEERRSHILVSEDQLSLAIGKEGQNVRLA
EEEEEEECCCCCEEEECCCCCCCCCCEEEECCHHHCCEEEEECCCEEEEECCCCCCEEEE
ARLTGWKIDIKDTNRYDHAEEDSKVAAEVSHRQALAEQEENKIEESELEVIENTFDKNFN
EEEECEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
EPDDSF
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]