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The map label for this gene is ddl [H]

Identifier: 113476541

GI number: 113476541

Start: 4621711

End: 4622796

Strand: Reverse

Name: ddl [H]

Synonym: Tery_2971

Alternate gene names: 113476541

Gene position: 4622796-4621711 (Counterclockwise)

Preceding gene: 113476542

Following gene: 113476540

Centisome position: 59.65

GC content: 40.88

Gene sequence:

>1086_bases
ATGAAGTTAGAAAAAATCAATCAAAATCAACACTCATCCTTAGCCACAATGAATAGATTACAAGTCTTGCACCTGGCAGG
TTCCCGTGTTTCCGAATTCTACTACAACCTATCAATACTCTATGCCAAAGAAGTAGTGCAACCAGTTGGAGTCAGCAGTT
ATTATGCAGTAGTACATCCTGATGGTCTTTGGCAGTTGGGAGCTTCTTTAGATTCATTATCAGAAAAGATGTTACTTCAG
GACATGATTCTGCAACTGCCTCAAATTGATGTTGTAGTTCCCCACATGTTCTGCTTTCTTGGTATGACCAGTTTCCGAGC
ATTTTTTGAGGATATGCTTAATCTACCTTTAGTGGGGTCACCATCCTATTGTACGGCACTAGCAACTAACAAAGCTCAGA
CGCGGAATGTTGTTTTGGCATCTGGGGTACAAGTAGCTAAAGCGCAGCAACTAGGGCGGGGAGAAACTTTAACAATGAAA
CCTCCTTTTGTTGTGAAACCAACTTCGGAAGATAATTCTTTGGGGTTAACATTGGTGTGGGATGAATCTCAGATAGAAGC
AGCCTTGGATAAGGGGTTTGAATTAGACAATAAATTGTTGGTTGAAGATTATATTCCTGGAAGGGAATTGCGTGTAGCTG
TAGTTGAGCGAGAGAGTAAGTTGTCTGTCTTGCCGATGATAGAATATTTAGTCACAGAAGAACACCCTATTAGAACTGTA
CATGATAAATATGTACTTCAATCTGATGGAACTCCTGGAAAGCAACCTGAGAAACCTATAGCTCAACCAATTTGTCCGGC
GAATGTTACTCCAGAGTTATTTGAAAAACTAGTAAACGCAGCTAAAAATGCTCATATTGCATTGGGTTGTCGCGACTATT
CTTTGTATGATTTCCGGGTACATGCTGAAACTAATGAGCCATATTTTCTGGAAGCAGGCTTATTCTGGGGTTTTGGGAAA
ATTAGTATGATTTCGCGGATGCTTCAAGCTGATGGGCAAAGTTTGGAGGATGTATCCCTAGAGTTGTGGAGTGCAGCAGC
AGGAAGAACTCGTGTGGCTTGTGGTTCTTTATTTAAGTGGAATTAA

Upstream 100 bases:

>100_bases
TTATCAAAAAAGTTATTCGACCTATGTTAATTACTTAATAATTGAAGTATCAAAATTCCTAAATACTGTTAGTATAGAAC
AATCTAAAATAACAATAATT

Downstream 100 bases:

>100_bases
AAAAGCGGATAACTGTTAGTATTTAATTAGTCAAAAAATATAAAATAAAAATAATTAGTAATGAAATTAGAAGAAATTAA
TCAAAATCAACACTCATCCT

Product: D-alanine--D-alanine ligase

Products: NA

Alternate protein names: D-Ala-D-Ala ligase; D-alanylalanine synthetase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MKLEKINQNQHSSLATMNRLQVLHLAGSRVSEFYYNLSILYAKEVVQPVGVSSYYAVVHPDGLWQLGASLDSLSEKMLLQ
DMILQLPQIDVVVPHMFCFLGMTSFRAFFEDMLNLPLVGSPSYCTALATNKAQTRNVVLASGVQVAKAQQLGRGETLTMK
PPFVVKPTSEDNSLGLTLVWDESQIEAALDKGFELDNKLLVEDYIPGRELRVAVVERESKLSVLPMIEYLVTEEHPIRTV
HDKYVLQSDGTPGKQPEKPIAQPICPANVTPELFEKLVNAAKNAHIALGCRDYSLYDFRVHAETNEPYFLEAGLFWGFGK
ISMISRMLQADGQSLEDVSLELWSAAAGRTRVACGSLFKWN

Sequences:

>Translated_361_residues
MKLEKINQNQHSSLATMNRLQVLHLAGSRVSEFYYNLSILYAKEVVQPVGVSSYYAVVHPDGLWQLGASLDSLSEKMLLQ
DMILQLPQIDVVVPHMFCFLGMTSFRAFFEDMLNLPLVGSPSYCTALATNKAQTRNVVLASGVQVAKAQQLGRGETLTMK
PPFVVKPTSEDNSLGLTLVWDESQIEAALDKGFELDNKLLVEDYIPGRELRVAVVERESKLSVLPMIEYLVTEEHPIRTV
HDKYVLQSDGTPGKQPEKPIAQPICPANVTPELFEKLVNAAKNAHIALGCRDYSLYDFRVHAETNEPYFLEAGLFWGFGK
ISMISRMLQADGQSLEDVSLELWSAAAGRTRVACGSLFKWN
>Mature_361_residues
MKLEKINQNQHSSLATMNRLQVLHLAGSRVSEFYYNLSILYAKEVVQPVGVSSYYAVVHPDGLWQLGASLDSLSEKMLLQ
DMILQLPQIDVVVPHMFCFLGMTSFRAFFEDMLNLPLVGSPSYCTALATNKAQTRNVVLASGVQVAKAQQLGRGETLTMK
PPFVVKPTSEDNSLGLTLVWDESQIEAALDKGFELDNKLLVEDYIPGRELRVAVVERESKLSVLPMIEYLVTEEHPIRTV
HDKYVLQSDGTPGKQPEKPIAQPICPANVTPELFEKLVNAAKNAHIALGCRDYSLYDFRVHAETNEPYFLEAGLFWGFGK
ISMISRMLQADGQSLEDVSLELWSAAAGRTRVACGSLFKWN

Specific function: Cell wall formation [H]

COG id: COG1181

COG function: function code M; D-alanine-D-alanine ligase and related ATP-grasp enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Escherichia coli, GI1786579, Length=275, Percent_Identity=28, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786280, Length=240, Percent_Identity=25.8333333333333, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR000291
- InterPro:   IPR005905
- InterPro:   IPR011095
- InterPro:   IPR011127
- InterPro:   IPR013817
- InterPro:   IPR016185 [H]

Pfam domain/function: PF07478 Dala_Dala_lig_C; PF01820 Dala_Dala_lig_N [H]

EC number: =6.3.2.4 [H]

Molecular weight: Translated: 40241; Mature: 40241

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEKINQNQHSSLATMNRLQVLHLAGSRVSEFYYNLSILYAKEVVQPVGVSSYYAVVHP
CCCCCCCCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHEEEHHHHHCCCCCCCEEEEECC
DGLWQLGASLDSLSEKMLLQDMILQLPQIDVVVPHMFCFLGMTSFRAFFEDMLNLPLVGS
CCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PSYCTALATNKAQTRNVVLASGVQVAKAQQLGRGETLTMKPPFVVKPTSEDNSLGLTLVW
CCHHEEEECCCCHHCCEEEECCCHHHHHHHCCCCCEEEECCCEEEECCCCCCCEEEEEEE
DESQIEAALDKGFELDNKLLVEDYIPGRELRVAVVERESKLSVLPMIEYLVTEEHPIRTV
CCHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEC
HDKYVLQSDGTPGKQPEKPIAQPICPANVTPELFEKLVNAAKNAHIALGCRDYSLYDFRV
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCEEEEEEE
HAETNEPYFLEAGLFWGFGKISMISRMLQADGQSLEDVSLELWSAAAGRTRVACGSLFKW
EECCCCCEEEECCCEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCCCC
N
C
>Mature Secondary Structure
MKLEKINQNQHSSLATMNRLQVLHLAGSRVSEFYYNLSILYAKEVVQPVGVSSYYAVVHP
CCCCCCCCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHEEEHHHHHCCCCCCCEEEEECC
DGLWQLGASLDSLSEKMLLQDMILQLPQIDVVVPHMFCFLGMTSFRAFFEDMLNLPLVGS
CCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PSYCTALATNKAQTRNVVLASGVQVAKAQQLGRGETLTMKPPFVVKPTSEDNSLGLTLVW
CCHHEEEECCCCHHCCEEEECCCHHHHHHHCCCCCEEEECCCEEEECCCCCCCEEEEEEE
DESQIEAALDKGFELDNKLLVEDYIPGRELRVAVVERESKLSVLPMIEYLVTEEHPIRTV
CCHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEC
HDKYVLQSDGTPGKQPEKPIAQPICPANVTPELFEKLVNAAKNAHIALGCRDYSLYDFRV
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCEEEEEEE
HAETNEPYFLEAGLFWGFGKISMISRMLQADGQSLEDVSLELWSAAAGRTRVACGSLFKW
EECCCCCEEEECCCEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA